{"id":"https://openalex.org/W2478842425","doi":"https://doi.org/10.1002/9781118695692.ch51","title":"The Murphy Indole Synthesis","display_name":"The Murphy Indole Synthesis","publication_year":2016,"publication_date":"2016-06-17","ids":{"openalex":"https://openalex.org/W2478842425","doi":"https://doi.org/10.1002/9781118695692.ch51","mag":"2478842425"},"language":"en","primary_location":{"id":"doi:10.1002/9781118695692.ch51","doi":"https://doi.org/10.1002/9781118695692.ch51","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781118695692.ch51","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indole Ring Synthesis","raw_type":"other"},"volume":{"id":"https://openalex.org/W4248040139","display_name":"Indole Ring Synthesis"},"type":"other","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049245360","display_name":"Gordon W. Gribble","orcid":"https://orcid.org/0000-0002-7573-0927","observed_orcids":["https://orcid.org/0000-0002-7573-0927"]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gordon W. Gribble","raw_affiliation_strings":["Department of Chemistry, Dartmouth College, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Dartmouth College, USA","institution_ids":["https://openalex.org/I107672454"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5049245360"],"corresponding_institution_ids":["https://openalex.org/I107672454"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"412","last_page":"413"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12973","display_name":"Synthesis of Indole Derivatives","score":0.7470999956130981,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12973","display_name":"Synthesis of Indole Derivatives","score":0.7470999956130981,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10701","display_name":"Radical Photochemical Reactions","score":0.2280000001192093,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11611","display_name":"Cyclopropane Reaction Mechanisms","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/indole-synthesis","display_name":"indole synthesis","score":0.9070000052452087},{"id":"https://openalex.org/keywords/aryl-diazonium-salts","display_name":"aryl diazonium salts","score":0.7710000276565552},{"id":"https://openalex.org/keywords/o-nitroaniline","display_name":"o-nitroaniline","score":0.8050000071525574},{"id":"https://openalex.org/keywords/aryl-radicals","display_name":"aryl radicals","score":0.6639999747276306},{"id":"https://openalex.org/keywords/tetrakis-dimethylamino-ethylene","display_name":"tetrakis(dimethylamino)ethylene","score":0.9259999990463257},{"id":"https://openalex.org/keywords/radical-cyclization","display_name":"radical cyclization","score":0.7850000262260437}],"concepts":[{"id":"https://openalex.org/C192527728","wikidata":"https://www.wikidata.org/wiki/Q1465700","display_name":"Indole test","level":2,"score":0.8383856415748596},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7858284711837769},{"id":"https://openalex.org/C139066938","wikidata":"https://www.wikidata.org/wiki/Q185056","display_name":"Radical","level":2,"score":0.7067157030105591},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.6903917789459229},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.6824106574058533},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.5822855234146118},{"id":"https://openalex.org/C126661725","wikidata":"https://www.wikidata.org/wiki/Q903420","display_name":"Isomerization","level":3,"score":0.5735622644424438},{"id":"https://openalex.org/C2778597550","wikidata":"https://www.wikidata.org/wiki/Q151313","display_name":"Ethylene","level":3,"score":0.48308423161506653},{"id":"https://openalex.org/C2909835963","wikidata":"https://www.wikidata.org/wiki/Q410255","display_name":"Diazonium Compounds","level":2,"score":0.47829657793045044},{"id":"https://openalex.org/C2781076698","wikidata":"https://www.wikidata.org/wiki/Q718074","display_name":"Aryl","level":3,"score":0.4496423006057739},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.43187594413757324},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.36604249477386475},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.3310585021972656},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.13779717683792114},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.084759920835495},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.07570663094520569},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9781118695692.ch51","doi":"https://doi.org/10.1002/9781118695692.ch51","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781118695692.ch51","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indole Ring Synthesis","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1984139543","https://openalex.org/W2021150201","https://openalex.org/W2041806672","https://openalex.org/W2064905356","https://openalex.org/W2099349537","https://openalex.org/W2110435559","https://openalex.org/W2139561438","https://openalex.org/W2159253086","https://openalex.org/W2951388146"],"related_works":["https://openalex.org/W7028640787","https://openalex.org/W4400068279","https://openalex.org/W2159253086","https://openalex.org/W2950220006","https://openalex.org/W2952609012","https://openalex.org/W2505436283","https://openalex.org/W2758950617","https://openalex.org/W4313389827","https://openalex.org/W1980663602","https://openalex.org/W2029705774"],"abstract_inverted_index":{"Following":[0],"the":[1,4,41,60,84],"exploration":[2],"of":[3,7,62,86],"synthetic":[5],"utility":[6],"aren-ediazonium":[8],"salts":[9,31],"in":[10,70],"radical":[11,57],"formation":[12],"and":[13,66,74],"cyclization,":[14],"radical-polar":[15],"crossover,":[16],"Murphy":[17,56,73],"described":[18],"a":[19,80],"new":[20,81],"indole":[21,44],"synthesis":[22],"based":[23],"on":[24],"his":[25],"methodology.":[26],"The":[27,55],"requisite":[28],"precursor":[29],"diazonium":[30],"can":[32,50],"be":[33,51],"rapidly":[34],"assembled":[35],"from":[36,89],"o-nitroaniline.":[37],"In":[38],"cases":[39],"where":[40],"fully":[42],"aromatic":[43],"ring":[45],"is":[46,67],"not":[47],"obtained,":[48],"isomerization":[49],"achieved":[52],"with":[53],"acid.":[54],"indolization":[58],"avoids":[59],"use":[61],"toxic":[63],"tin":[64],"compounds":[65],"often":[68],"superior":[69],"product":[71],"yield.":[72],"coworkers":[75],"presented":[76],"tetrakis(dimethylamino)ethylene":[77],"(TDAE)":[78],"as":[79],"reagent":[82],"for":[83],"generation":[85],"aryl":[87],"radicals":[88],"arenediazonium":[90],"salts.":[91]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-08-23T00:00:00"}