{"id":"https://openalex.org/W2476968031","doi":"https://doi.org/10.1201/9781420008517-19","title":"RNA Silencing in the Aspergilli","display_name":"RNA Silencing in the Aspergilli","publication_year":2007,"publication_date":"2007-12-07","ids":{"openalex":"https://openalex.org/W2476968031","doi":"https://doi.org/10.1201/9781420008517-19","mag":"2476968031"},"language":"en","primary_location":{"id":"doi:10.1201/9781420008517-19","doi":"https://doi.org/10.1201/9781420008517-19","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9781420008517-19","pdf_url":null,"source":{"id":"https://openalex.org/S4306463075","display_name":"CRC Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aspergilli","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W1786205426","display_name":"The Aspergilli"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072578150","display_name":"Thomas M. Hammond","orcid":"https://orcid.org/0000-0002-0812-4759","observed_orcids":["https://orcid.org/0000-0002-0812-4759"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas M. Hammond","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5031263971","display_name":"Nancy P. Keller","orcid":"https://orcid.org/0000-0002-4386-9473","observed_orcids":["https://orcid.org/0000-0002-4386-9473"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nancy P. Keller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4567,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.69939436,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"217","last_page":"230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.4392000138759613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.4392000138759613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.19140000641345978,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.05889999866485596,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna-silencing","display_name":"RNA silencing","score":0.9890000224113464},{"id":"https://openalex.org/keywords/aspergillus","display_name":"Aspergillus","score":0.8519999980926514},{"id":"https://openalex.org/keywords/aspergillus-fumigatus","display_name":"Aspergillus fumigatus","score":0.8949999809265137},{"id":"https://openalex.org/keywords/aspergillus-flavus","display_name":"Aspergillus flavus","score":0.9929999709129333},{"id":"https://openalex.org/keywords/aspergillus-parasiticus","display_name":"Aspergillus parasiticus","score":1.0},{"id":"https://openalex.org/keywords/aspergillus-nidulans","display_name":"Aspergillus nidulans","score":0.9950000047683716},{"id":"https://openalex.org/keywords/dicer","display_name":"Dicer","score":0.7720000147819519},{"id":"https://openalex.org/keywords/argonaute-proteins","display_name":"Argonaute proteins","score":0.9850000143051147},{"id":"https://openalex.org/keywords/rna-dependent-rna-polymerase","display_name":"RNA-dependent RNA polymerase","score":0.9860000014305115},{"id":"https://openalex.org/keywords/meiotic-silencing","display_name":"meiotic silencing","score":0.7300000190734863},{"id":"https://openalex.org/keywords/quelling","display_name":"quelling","score":0.9459999799728394},{"id":"https://openalex.org/keywords/small-rna","display_name":"small RNA","score":0.718999981880188},{"id":"https://openalex.org/keywords/antiviral-defense","display_name":"antiviral defense","score":0.6520000100135803}],"concepts":[{"id":"https://openalex.org/C2191507","wikidata":"https://www.wikidata.org/wiki/Q7277185","display_name":"RNA silencing","level":5,"score":0.489122211933136},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3022531270980835},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.29952144622802734},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.26702553033828735},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21053650975227356},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08209392428398132}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1201/9781420008517-19","doi":"https://doi.org/10.1201/9781420008517-19","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9781420008517-19","pdf_url":null,"source":{"id":"https://openalex.org/S4306463075","display_name":"CRC Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aspergilli","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W1989454102"],"related_works":["https://openalex.org/W1969538789","https://openalex.org/W2150058986","https://openalex.org/W4362604826","https://openalex.org/W3082667343","https://openalex.org/W7098143711","https://openalex.org/W2363345973","https://openalex.org/W7096056061","https://openalex.org/W2099275684","https://openalex.org/W1983871012","https://openalex.org/W2132348613"],"abstract_inverted_index":{"CONTENTS":[0],"13.1":[1,113],"Introduction":[2,114],".............................................................................................................................":[3],"197":[4],"13.2":[5],"Experimental":[6,26,37],"RNA":[7,27,38,45,51,61,75,84,142,148,152,160,175,204,233,260,297,333],"Silencing":[8,28,39,46,52,62,85,92,102],".................................................................................................":[9],"198":[10,15,24],"13.2.1":[11],"Aspergillus":[12,17,21,43,55,60,83],"fumigatus":[13],"................................................................................................":[14],"13.2.2":[16],"fl":[18],"avus":[19],"and":[20,69,133,144,158,208,224,237,314],"parasiticus":[22],".........................................................":[23],"13.2.3":[25],"During":[29],"Infection":[30],"........................................................":[31,88],"199":[32,41,49],"13.3":[33],"Genetic":[34],"Analysis":[35],"of":[36,82,217,308,317,327,356],"................................................................":[40],"13.3.1":[42],"nidulans":[44,56],"Model":[47],".............................................................":[48,103],"13.3.2":[50],"Proteins":[53],"in":[54,86,140,180,243,259,291,302,311,320],"......................................................":[57],"200":[58,66],"13.4":[59],"Gene":[63],"Evolution":[64],"...........................................................................":[65],"13.4.1":[67],"Dicers":[68],"Argonautes":[70],"...............................................................................................":[71],"201":[72,78],"13.4.2":[73],"RNA-Dependent":[74],"Polymerases":[76],"..........................................................................":[77],"13.5":[79],"Possible":[80],"Roles":[81],"Nature":[87],"203":[89,94],"13.5.1":[90],"Meiotic":[91],".......................................................................................................":[93],"13.5.2":[95],"Quelling":[96],".....................................................................................................................":[97],"204":[98,104],"13.5.3":[99],"RNAi-Mediated":[100],"Heterochromatic":[101],"13.6":[105],"Future":[106],"Directions":[107],"....................................................................................................................":[108],"205":[109],"References":[110],"..........................................................................................................................................":[111],"206":[112],"Small":[115],"noncoding":[116],"RNAs":[117,184,274],"have":[118,293],"numerous":[119],"biological":[120,289],"functions,":[121],"mediating":[122],"processes":[123,262,346],"such":[124,193],"as":[125,194],"post-transcriptional":[126],"gene":[127],"silencing,":[128,130],"heterochromatic":[129,318,324],"antiviral":[131],"defense,":[132],"transposable":[134],"element":[135],"control.1-3":[136],"The":[137,228],"proteins":[138,154,213],"involved":[139],"small":[141,174,183,203,232,273],"use":[143],"production":[145],"are":[146,155,185,214,255,347],"called":[147],"silencing":[149,153,197,261,307,319,334],"proteins.":[150],"Core":[151],"Dicer,":[156],"Argonaute,":[157],"RNA-dependent":[159],"polymerase":[161],"(RDRP).":[162],"Dicer":[163,267],"is":[164,329,352],"an":[165],"RNAseIII-containing":[166],"protein":[167],"responsible":[168],"for":[169,266,275],"processing":[170,268],"dsRNA":[171,265],"into":[172,187,277],"various":[173],"species,":[176],"typically":[177],"21-25":[178],"nt":[179],"length.4,5":[181],"Dicer-processed":[182],"incorporated":[186,202],"Argonaute":[188,212],"-":[189],"containing":[190],"effector":[191,278],"complexes,":[192,245],"RISC":[195,244],"(RNA-induced":[196],"complex),":[198],"which":[199],"uses":[200],"the":[201,238,281,349],"to":[205,257,296],"fi":[206],"nd":[207],"cleave":[209],"complementary":[210],"mRNA.6":[211],"made":[215],"up":[216],"two":[218],"major":[219],"domains,":[220],"a":[221,225,247,285],"PAZ":[222,229],"domain":[223,230],"Piwi":[226,239],"domain.7,8":[227],"has":[231],"binding":[234],"activity":[235,249],"9,10":[236],"domain,":[240],"at":[241],"least":[242],"contains":[246],"\u201cslicer\u201d":[248],"that":[250,361],"degrades":[251],"target":[252],"mRNAs.11-13":[253],"RDRPs":[254],"thought":[256],"participate":[258],"by":[263,270],"forming":[264,272],"or":[269],"directly":[271],"incorporation":[276],"complexes.2,14-16":[279],"In":[280],"last":[282],"10":[283],"years":[284],"few":[286],"specifi":[287,340],"c":[288,341],"phenomena":[290],"fungi":[292],"been":[294],"linked":[295],"silencing.":[298],"These":[299],"include":[300],"cosuppression":[301],"Neurospora":[303],"crassa":[304],"(quelling),17":[305],"meiotic":[306],"unpaired":[309],"DNA":[310],"N.":[312],"crassa,18":[313],"some":[315],"types":[316],"Schizosaccharomyces":[321],"pombe":[322],"(RNAi-mediated":[323],"silencing).19":[325],"Most":[326],"what":[328],"known":[330],"about":[331],"fungal":[332,358],"stems":[335],"from":[336],"work":[337],"on":[338],"these":[339,345],"phenomena.":[342],"How":[343],"common":[344],"across":[348],"Fungal":[350],"Kingdom":[351],"unknown,":[353],"but":[354],"analysis":[355],"available":[357],"genomes":[359],"suggests":[360],"they":[362],"cannot":[363],"be":[364],"fundamentally":[365],"conserved.":[366]},"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-08-23T00:00:00"}