{"id":"https://openalex.org/W2476910046","doi":"https://doi.org/10.1007/978-3-642-69770-8_213","title":"DNA Restriction Fragment Length Polymorphism of the Human Class II Genes as Analyzed by Southern Blotting Technique","display_name":"DNA Restriction Fragment Length Polymorphism of the Human Class II Genes as Analyzed by Southern Blotting Technique","publication_year":1984,"publication_date":"1984-01-01","ids":{"openalex":"https://openalex.org/W2476910046","doi":"https://doi.org/10.1007/978-3-642-69770-8_213","mag":"2476910046"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-69770-8_213","doi":"https://doi.org/10.1007/978-3-642-69770-8_213","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-69770-8_213","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histocompatibility Testing 1984","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4298018328","display_name":"Histocompatibility Testing 1984"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064106919","display_name":"Kam Man Hui","orcid":"https://orcid.org/0000-0003-1820-1399","observed_orcids":["https://orcid.org/0000-0003-1820-1399"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K. M. Hui","raw_affiliation_strings":["Department of Immunology, The London Hospital Medical College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, The London Hospital Medical College, London, UK","institution_ids":["https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071424723","display_name":"A. V. Groves","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. V. Groves","raw_affiliation_strings":["Department of Immunology, The London Hospital Medical College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, The London Hospital Medical College, London, UK","institution_ids":["https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006181606","display_name":"Dolores Jaraquemada","orcid":"https://orcid.org/0000-0003-3328-740X","observed_orcids":["https://orcid.org/0000-0003-3328-740X"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. Jaraquemada","raw_affiliation_strings":["Department of Immunology, The London Hospital Medical College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, The London Hospital Medical College, London, UK","institution_ids":["https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056347519","display_name":"Frank G. Grosveld","orcid":"https://orcid.org/0000-0002-7051-4715","observed_orcids":["https://orcid.org/0000-0002-7051-4715"]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"F. Grosveld","raw_affiliation_strings":["Laboratory of Gene Structure and Expression, National Institute for Medical Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression, National Institute for Medical Research, London, UK","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110135635","display_name":"J. Awad","orcid":"https://orcid.org/0000-0002-1264-1847","observed_orcids":["https://orcid.org/0000-0002-1264-1847"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Awad","raw_affiliation_strings":["Department of Immunology, The London Hospital Medical College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, The London Hospital Medical College, London, UK","institution_ids":["https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052488118","display_name":"Cristina Navarrete","orcid":"https://orcid.org/0000-0002-4431-3784","observed_orcids":["https://orcid.org/0000-0002-4431-3784"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C. Navarrete","raw_affiliation_strings":["Department of Immunology, The London Hospital Medical College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, The London Hospital Medical College, London, UK","institution_ids":["https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059986913","display_name":"John Trowsdale","orcid":"https://orcid.org/0000-0002-0150-5698","observed_orcids":["https://orcid.org/0000-0002-0150-5698"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Trowsdale","raw_affiliation_strings":["Imperial Cancer Research Fund, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imperial Cancer Research Fund, London, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"E. Murray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285715","display_name":"National Institute for Medical Research","ror":"https://ror.org/00146rb91","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054","https://openalex.org/I4210087105","https://openalex.org/I4405285715","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. Murray","raw_affiliation_strings":["Laboratory of Gene Structure and Expression, National Institute for Medical Research, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Gene Structure and Expression, National Institute for Medical Research, London, UK","institution_ids":["https://openalex.org/I4405285715"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008893540","display_name":"HILLIARD FESTENSTEIN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"H. Festenstein","raw_affiliation_strings":["Department of Immunology, The London Hospital Medical College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, The London Hospital Medical College, London, UK","institution_ids":["https://openalex.org/I166337079"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.6159,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.97165992,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"590","last_page":"594"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.05000000074505806,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hla-class-ii-genes","display_name":"HLA class II genes","score":0.9100000262260437},{"id":"https://openalex.org/keywords/restriction-fragment-length-polymorphism","display_name":"restriction fragment length polymorphism","score":0.8550000190734863},{"id":"https://openalex.org/keywords/hla-d-region","display_name":"HLA-D region","score":0.7720000147819519},{"id":"https://openalex.org/keywords/hla-dr","display_name":"HLA-DR","score":0.8989999890327454},{"id":"https://openalex.org/keywords/hla-dq","display_name":"HLA-DQ","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hla-dp","display_name":"HLA-DP","score":0.8930000066757202},{"id":"https://openalex.org/keywords/major-histocompatibility-complex","display_name":"major histocompatibility complex","score":0.9269999861717224},{"id":"https://openalex.org/keywords/human-leukocyte-antigen","display_name":"human leukocyte antigen","score":0.5580000281333923},{"id":"https://openalex.org/keywords/chromosome-6","display_name":"chromosome 6","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.6545417904853821},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6507317423820496},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5695849657058716},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.5505346655845642},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5219525694847107},{"id":"https://openalex.org/C2781209916","wikidata":"https://www.wikidata.org/wiki/Q3215756","display_name":"Typing","level":2,"score":0.5157911777496338},{"id":"https://openalex.org/C168007829","wikidata":"https://www.wikidata.org/wiki/Q857299","display_name":"Restriction fragment length polymorphism","level":4,"score":0.5118538737297058},{"id":"https://openalex.org/C133307689","wikidata":"https://www.wikidata.org/wiki/Q48749","display_name":"Southern blot","level":3,"score":0.5054879188537598},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4991452693939209},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4927113354206085},{"id":"https://openalex.org/C84289048","wikidata":"https://www.wikidata.org/wiki/Q7316314","display_name":"Restriction fragment","level":3,"score":0.4398420453071594},{"id":"https://openalex.org/C2779910283","wikidata":"https://www.wikidata.org/wiki/Q5630144","display_name":"HLA-DQ","level":5,"score":0.4343666434288025},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.4277122914791107},{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.21073028445243835},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.17302605509757996}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-69770-8_213","doi":"https://doi.org/10.1007/978-3-642-69770-8_213","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-69770-8_213","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histocompatibility Testing 1984","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W430181905","https://openalex.org/W1975402564","https://openalex.org/W1984156045","https://openalex.org/W1991309462","https://openalex.org/W2004484950","https://openalex.org/W2010867882","https://openalex.org/W2029987769","https://openalex.org/W2060892797","https://openalex.org/W2063450941","https://openalex.org/W2115976389","https://openalex.org/W2412955563"],"related_works":["https://openalex.org/W2414531262","https://openalex.org/W2498182490","https://openalex.org/W234978553","https://openalex.org/W1462897814","https://openalex.org/W6962719037","https://openalex.org/W2484294563","https://openalex.org/W2277013572","https://openalex.org/W2023724277","https://openalex.org/W2297499504","https://openalex.org/W70733418"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-24T09:50:30.924529","created_date":"2016-08-23T00:00:00"}