{"id":"https://openalex.org/W2474636231","doi":"https://doi.org/10.1104/pp.16.01195","title":"Cytosolic Glutamine Synthetase Gln1;2 Is the Main Isozyme Contributing to GS1 Activity and Can Be Up-Regulated to Relieve Ammonium Toxicity","display_name":"Cytosolic Glutamine Synthetase Gln1;2 Is the Main Isozyme Contributing to GS1 Activity and Can Be Up-Regulated to Relieve Ammonium Toxicity","publication_year":2016,"publication_date":"2016-05-26","ids":{"openalex":"https://openalex.org/W2474636231","doi":"https://doi.org/10.1104/pp.16.01195","mag":"2474636231","pmid":"https://pubmed.ncbi.nlm.nih.gov/27231101","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4936538"},"language":"en","primary_location":{"id":"doi:10.1104/pp.16.01195","doi":"https://doi.org/10.1104/pp.16.01195","is_oa":true,"landing_page_url":"https://doi.org/10.1104/pp.16.01195","pdf_url":null,"source":{"id":"https://openalex.org/S42294715","display_name":"PLANT PHYSIOLOGY","issn_l":"0032-0889","issn":["0032-0889","1532-2548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1104/pp.16.01195","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056433561","display_name":"Miao Guan","orcid":"https://orcid.org/0000-0002-3927-6990","observed_orcids":["https://orcid.org/0000-0002-3927-6990"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Miao Guan","raw_affiliation_strings":["Department of Plant and Environmental Sciences and Copenhagen Plant Science Center, Faculty of Science, University of Copenhagen, DK-1871 Frederiksberg C, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-3927-6990","affiliations":[{"raw_affiliation_string":"Department of Plant and Environmental Sciences and Copenhagen Plant Science Center, Faculty of Science, University of Copenhagen, DK-1871 Frederiksberg C, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008563318","display_name":"Thomas C. de Bang","orcid":"https://orcid.org/0000-0002-5019-6422","observed_orcids":["https://orcid.org/0000-0002-5019-6422"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Thomas C. de Bang","raw_affiliation_strings":["Department of Plant and Environmental Sciences and Copenhagen Plant Science Center, Faculty of Science, University of Copenhagen, DK-1871 Frederiksberg C, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-5019-6422","affiliations":[{"raw_affiliation_string":"Department of Plant and Environmental Sciences and Copenhagen Plant Science Center, Faculty of Science, University of Copenhagen, DK-1871 Frederiksberg C, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004045096","display_name":"Carsten Pedersen","orcid":"https://orcid.org/0000-0002-9520-2232","observed_orcids":["https://orcid.org/0000-0002-9520-2232"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Carsten Pedersen","raw_affiliation_strings":["Department of Plant and Environmental Sciences and Copenhagen Plant Science Center, Faculty of Science, University of Copenhagen, DK-1871 Frederiksberg C, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant and Environmental Sciences and Copenhagen Plant Science Center, Faculty of Science, University of Copenhagen, DK-1871 Frederiksberg C, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008567312","display_name":"Jan Kofod Schjoerring","orcid":"https://orcid.org/0000-0002-2852-3298","observed_orcids":["https://orcid.org/0000-0002-2852-3298"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Jan K. Schjoerring","raw_affiliation_strings":["Department of Plant and Environmental Sciences and Copenhagen Plant Science Center, Faculty of Science, University of Copenhagen, DK-1871 Frederiksberg C, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-2852-3298","affiliations":[{"raw_affiliation_string":"Department of Plant and Environmental Sciences and Copenhagen Plant Science Center, Faculty of Science, University of Copenhagen, DK-1871 Frederiksberg C, Denmark","institution_ids":["https://openalex.org/I124055696"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I124055696"],"apc_list":{"value":3851,"currency":"USD","value_usd":3851},"apc_paid":{"value":3851,"currency":"USD","value_usd":3851},"fwci":11.0983,"has_fulltext":false,"cited_by_count":125,"citation_normalized_percentile":{"value":0.98734209,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"171","issue":"3","first_page":"1921","last_page":"1933"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11247","display_name":"Plant nutrient uptake and metabolism","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11247","display_name":"Plant nutrient uptake and metabolism","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12566","display_name":"Nitrogen and Sulfur Effects on Brassica","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11470","display_name":"Legume Nitrogen Fixing Symbiosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glutamine-synthetase","display_name":"glutamine synthetase","score":0.8960000276565552},{"id":"https://openalex.org/keywords/isoenzymes","display_name":"isozymes","score":0.6869999766349792},{"id":"https://openalex.org/keywords/ammonia-assimilation","display_name":"ammonium assimilation","score":0.8880000114440918},{"id":"https://openalex.org/keywords/ammonium-toxicity","display_name":"ammonium toxicity","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ammonium-detoxification","display_name":"ammonium detoxification","score":0.8859999775886536},{"id":"https://openalex.org/keywords/nitrogen-assimilation","display_name":"nitrogen assimilation","score":0.5630000233650208},{"id":"https://openalex.org/keywords/amino-acid-synthesis","display_name":"amino acid synthesis","score":0.8360000252723694},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.7900000214576721},{"id":"https://openalex.org/keywords/knockout-mutants","display_name":"knockout mutants","score":0.5809999704360962},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.5339999794960022}],"concepts":[{"id":"https://openalex.org/C2779289688","wikidata":"https://www.wikidata.org/wiki/Q418306","display_name":"Glutamine synthetase","level":4,"score":0.9130520820617676},{"id":"https://openalex.org/C119795356","wikidata":"https://www.wikidata.org/wiki/Q407801","display_name":"Isozyme","level":3,"score":0.852238655090332},{"id":"https://openalex.org/C98539663","wikidata":"https://www.wikidata.org/wiki/Q220599","display_name":"Cytosol","level":3,"score":0.6797851324081421},{"id":"https://openalex.org/C2779870022","wikidata":"https://www.wikidata.org/wiki/Q190901","display_name":"Ammonium","level":2,"score":0.6506836414337158},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.5636849999427795},{"id":"https://openalex.org/C2779349466","wikidata":"https://www.wikidata.org/wiki/Q181619","display_name":"Glutamine","level":3,"score":0.4647836685180664},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46208521723747253},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4125971794128418},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3671033978462219},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3453691601753235},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.3342835605144501},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.07649001479148865},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D005974","descriptor_name":"Glutamate-Ammonia Ligase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005974","descriptor_name":"Glutamate-Ammonia Ligase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008658","descriptor_name":"Inactivation, Metabolic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009584","descriptor_name":"Nitrogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018520","descriptor_name":"Plant Shoots","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018520","descriptor_name":"Plant Shoots","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064751","descriptor_name":"Ammonium Compounds","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1104/pp.16.01195","doi":"https://doi.org/10.1104/pp.16.01195","is_oa":true,"landing_page_url":"https://doi.org/10.1104/pp.16.01195","pdf_url":null,"source":{"id":"https://openalex.org/S42294715","display_name":"PLANT PHYSIOLOGY","issn_l":"0032-0889","issn":["0032-0889","1532-2548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Physiology","raw_type":"journal-article"},{"id":"pmid:27231101","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27231101","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant physiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4936538","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4936538/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Physiol","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/d26b95c8-3c52-4cdb-bf7f-2928f29ac99d","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/d26b95c8-3c52-4cdb-bf7f-2928f29ac99d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Guan, M, de Bang, T C, Pedersen, C & Schj\u00f8rring, J K 2016, 'Cytosolic glutamine synthetase Gln1;2 is the main isozyme contributing to GS1 activity and can be up-regulated to relieve ammonium toxicity', Plant Physiology, vol. 171, no. 3, pp. 1921-1933. https://doi.org/10.1104/pp.16.01195","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1104/pp.16.01195","doi":"https://doi.org/10.1104/pp.16.01195","is_oa":true,"landing_page_url":"https://doi.org/10.1104/pp.16.01195","pdf_url":null,"source":{"id":"https://openalex.org/S42294715","display_name":"PLANT PHYSIOLOGY","issn_l":"0032-0889","issn":["0032-0889","1532-2548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.8409000039100647,"display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5589603111","display_name":null,"funder_award_id":"4084-00001B","funder_id":"https://openalex.org/F4320313796","funder_display_name":"Innovationsfonden"},{"id":"https://openalex.org/G6486973401","display_name":null,"funder_award_id":"2009618037","funder_id":"https://openalex.org/F4320322725","funder_display_name":"China Scholarship Council"}],"funders":[{"id":"https://openalex.org/F4320313796","display_name":"Innovationsfonden","ror":"https://ror.org/00daj4111"},{"id":"https://openalex.org/F4320322725","display_name":"China Scholarship Council","ror":"https://ror.org/04atp4p48"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W578953693","https://openalex.org/W1521651633","https://openalex.org/W1554255426","https://openalex.org/W1845619518","https://openalex.org/W1944200683","https://openalex.org/W1946618353","https://openalex.org/W1977660801","https://openalex.org/W1977904704","https://openalex.org/W1985447935","https://openalex.org/W1999634250","https://openalex.org/W2001139474","https://openalex.org/W2004443005","https://openalex.org/W2012973442","https://openalex.org/W2016527764","https://openalex.org/W2021782442","https://openalex.org/W2027827779","https://openalex.org/W2030307073","https://openalex.org/W2038330351","https://openalex.org/W2040418973","https://openalex.org/W2046941968","https://openalex.org/W2053427298","https://openalex.org/W2055445256","https://openalex.org/W2062721433","https://openalex.org/W2066807957","https://openalex.org/W2079389083","https://openalex.org/W2081787475","https://openalex.org/W2082056844","https://openalex.org/W2083797275","https://openalex.org/W2085420439","https://openalex.org/W2086491289","https://openalex.org/W2091226051","https://openalex.org/W2094902022","https://openalex.org/W2095424461","https://openalex.org/W2101243221","https://openalex.org/W2108244474","https://openalex.org/W2113094233","https://openalex.org/W2113930201","https://openalex.org/W2116122104","https://openalex.org/W2123288588","https://openalex.org/W2128876341","https://openalex.org/W2135580017","https://openalex.org/W2136905758","https://openalex.org/W2142368802","https://openalex.org/W2145742161","https://openalex.org/W2147301693","https://openalex.org/W2147754135","https://openalex.org/W2149271112","https://openalex.org/W2154854735","https://openalex.org/W2161321807","https://openalex.org/W2161645265","https://openalex.org/W2165482953","https://openalex.org/W2171219018","https://openalex.org/W2299203112","https://openalex.org/W2324678770","https://openalex.org/W2333840291"],"related_works":["https://openalex.org/W2563987430","https://openalex.org/W2793855296","https://openalex.org/W2147301693","https://openalex.org/W2021782442","https://openalex.org/W2149271112","https://openalex.org/W2036070632","https://openalex.org/W7098764974","https://openalex.org/W2171219018","https://openalex.org/W2199065332","https://openalex.org/W2805244717"],"abstract_inverted_index":{"Cytosolic":[0],"GS1":[1,19,26,151,196],"(Gln":[2],"synthetase)":[3],"is":[4,189],"central":[5],"for":[6,101,178],"ammonium":[7,12,55,102,118,165,179,208],"assimilation":[8,180],"in":[9,28,62,76,85,99,156,198,221],"plants.":[10],"High":[11],"treatment":[13,56],"enhanced":[14],"the":[15,18,34,37,40,89,93,122,129,135,140,164,190],"expression":[16,38,48],"of":[17,39,49,92,121,134,148,170,219],"isogene":[20],"Gln-1;2":[21,98,175,188,220],"encoding":[22],"a":[23,68,81,215],"low-affinity":[24],"high-capacity":[25],"protein":[27],"Arabidopsis":[29,222],"(Arabidopsis":[30],"thaliana)":[31],"shoots.":[32,223],"Under":[33],"same":[35],"conditions,":[36],"high-affinity":[41],"low-capacity":[42],"isoform":[43],"Gln-1;1":[44,96],"was":[45,73,144,153,176],"reduced.":[46],"The":[47],"Gln-1;3":[50],"did":[51],"not":[52],"respond":[53],"to":[54,128,194,206,212],"while":[57,132,168],"Gln-1;4":[58],"and":[59,97,105,139,159,181,202],"Gln-1;5":[60],"isogenes":[61,95],"all":[63],"cases":[64],"were":[65,109,126],"expressed":[66,75],"at":[67,80],"very":[69,82],"low":[70,83],"level.":[71],"Gln-2":[72],"highly":[74],"shoots":[77,100],"but":[78],"only":[79],"level":[84],"roots.":[86],"To":[87],"investigate":[88],"specific":[90],"functions":[91],"two":[94],"detoxification,":[103],"single":[104,123,137],"double":[106,142],"knock-out":[107],"mutants":[108],"grown":[110],"under":[111],"standard":[112],"N":[113,149],"supply":[114],"or":[115],"with":[116,162],"high":[117],"provision.":[119],"Phenotypes":[120],"mutant":[124,138,143],"gln1;1":[125],"similar":[127],"wild":[130],"type,":[131],"growth":[133,200],"gln1;2":[136,158],"gln1;1:gln1;2":[141,160],"significantly":[145,154],"impaired":[146],"irrespective":[147],"regime.":[150],"activity":[152,197],"reduced":[155],"both":[157],"Along":[161],"this,":[163],"content":[166],"increased":[167],"that":[169,174,187],"Gln":[171],"decreased,":[172],"showing":[173],"essential":[177],"amino":[182],"acid":[183],"synthesis.":[184],"We":[185],"conclude":[186],"main":[191],"isozyme":[192],"contributing":[193],"shoot":[195,217],"vegetative":[199],"stages":[201],"can":[203],"be":[204],"up-regulated":[205],"relieve":[207],"toxicity.":[209],"This":[210],"reveals,":[211],"our":[213],"knowledge,":[214],"novel":[216],"function":[218]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":20},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":14},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-07-22T00:00:00"}