{"id":"https://openalex.org/W2473983240","doi":null,"title":"Receptor-mediated endocytosis of transferrin and ferritin by guinea-pig reticulocytes. Uptake by a common endocytic pathway.","display_name":"Receptor-mediated endocytosis of transferrin and ferritin by guinea-pig reticulocytes. Uptake by a common endocytic pathway.","publication_year":1987,"publication_date":"1987-04-01","ids":{"openalex":"https://openalex.org/W2473983240","mag":"2473983240","pmid":"https://pubmed.ncbi.nlm.nih.gov/3036529"},"language":"en","primary_location":{"id":"pmid:3036529","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3036529","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of cell biology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015461060","display_name":"G D Blight","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G D Blight","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111843091","display_name":"Evan Huxley Morgan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E H Morgan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6731,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.6167426,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"43","issue":"2","first_page":"260","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.029600000008940697,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transferrin","display_name":"transferrin","score":0.8100000023841858},{"id":"https://openalex.org/keywords/ferritin","display_name":"ferritin","score":1.0},{"id":"https://openalex.org/keywords/reticulocytes","display_name":"reticulocytes","score":0.8700000047683716},{"id":"https://openalex.org/keywords/receptor-mediated-endocytosis","display_name":"receptor-mediated endocytosis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/coated-pits","display_name":"coated pits","score":0.8450000286102295},{"id":"https://openalex.org/keywords/multivesicular-endosomes","display_name":"multivesicular endosomes","score":0.9459999799728394},{"id":"https://openalex.org/keywords/exocytosis","display_name":"exocytosis","score":0.6930000185966492},{"id":"https://openalex.org/keywords/transferrin-receptor","display_name":"transferrin receptor","score":0.699999988079071},{"id":"https://openalex.org/keywords/guinea-pig","display_name":"guinea pig","score":0.5709999799728394},{"id":"https://openalex.org/keywords/iron-absorption","display_name":"iron absorption","score":0.35499998927116394},{"id":"https://openalex.org/keywords/receptor-recycling","display_name":"receptor recycling","score":0.4429999887943268}],"concepts":[{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.9198126792907715},{"id":"https://openalex.org/C79747257","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytic cycle","level":4,"score":0.8952541351318359},{"id":"https://openalex.org/C22814914","wikidata":"https://www.wikidata.org/wiki/Q410473","display_name":"Transferrin","level":2,"score":0.8306715488433838},{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.8111701011657715},{"id":"https://openalex.org/C102747710","wikidata":"https://www.wikidata.org/wiki/Q824237","display_name":"Endosome","level":3,"score":0.7528977394104004},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.6553045511245728},{"id":"https://openalex.org/C32264632","wikidata":"https://www.wikidata.org/wiki/Q1134983","display_name":"Transferrin receptor","level":3,"score":0.5952522158622742},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5909327268600464},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.45127904415130615},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.44366446137428284},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4427696764469147},{"id":"https://openalex.org/C117943116","wikidata":"https://www.wikidata.org/wiki/Q1135604","display_name":"Receptor-mediated endocytosis","level":4,"score":0.4420641362667084},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4060420095920563},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.39790186285972595},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.338707834482193},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.20975711941719055}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004705","descriptor_name":"Endocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004910","descriptor_name":"Erythrocyte Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004910","descriptor_name":"Erythrocyte Membrane","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D005293","descriptor_name":"Ferritins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011990","descriptor_name":"Receptors, Transferrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D033862","descriptor_name":"Iron-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:3036529","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3036529","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of cell biology","raw_type":"Journal Article"},{"id":"mag:2473983240","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3036529","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2047167908","https://openalex.org/W2005993715","https://openalex.org/W2039375795","https://openalex.org/W2071138678","https://openalex.org/W2025457574","https://openalex.org/W2410758188","https://openalex.org/W1647656396","https://openalex.org/W1975765794","https://openalex.org/W129731631","https://openalex.org/W1930247312"],"abstract_inverted_index":{"Earlier":[0],"studies":[1],"have":[2,28],"shown":[3],"that":[4,143,160],"transferrin":[5,38,146],"binds":[6],"to":[7,66,99,131],"specific":[8,29],"receptors":[9,30],"on":[10],"the":[11,49,67,84,96,110,150],"reticulocyte":[12],"surface,":[13],"clusters":[14],"in":[15,83,167],"coated":[16,86,155],"pits":[17,87,156],"and":[18,37,55,80,88,113,117,145,157],"is":[19],"then":[20],"internalized":[21,148],"via":[22],"endocytic":[23,122,135],"vesicles.":[24,91],"Guinea-pig":[25],"reticulocytes":[26,42],"also":[27],"for":[31],"ferritin.":[32],"In":[33],"this":[34],"paper":[35],"ferritin":[36,54,81,116,144],"endocytosis":[39],"by":[40,45,77,119],"guinea-pig":[41],"was":[43],"studied":[44],"electron":[46,51],"microscopy":[47],"using":[48],"natural":[50],"density":[52],"of":[53,133],"colloidal":[56],"gold-transferrin":[57],"(AuTf).":[58],"At":[59,70],"4":[60],"degrees":[61,72],"C":[62,73],"both":[63],"ligands":[64,97],"bound":[65],"cell":[68],"surface.":[69],"37":[71],"progressive":[74],"uptake":[75],"occurred":[76],"endocytosis.":[78],"AuTf":[79,126],"clustered":[82],"same":[85,151],"small":[89],"intracellular":[90],"After":[92],"60":[93],"min":[94],"incubations":[95],"colocalized":[98],"large":[100],"multivesicular":[101],"endosomes":[102],"(MVE),":[103],"still":[104],"membrane-bound.":[105],"MVE":[106],"subsequently":[107],"fused":[108],"with":[109,125],"plasma":[111],"membrane":[112],"released":[114],"AuTf,":[115],"inclusions":[118],"exocytosis.":[120],"All":[121],"structures":[123,136],"labelled":[124],"contained":[127,137],"ferritin,":[128],"but":[129,159],"23":[130],"35%":[132],"ferritin-labelled":[134],"no":[138],"AuTf.":[139],"These":[140],"data":[141],"suggest":[142],"are":[147,163],"through":[149],"pathway":[152],"involving":[153],"receptors,":[154],"vesicles,":[158],"these":[161],"proteins":[162],"recycled":[164],"only":[165],"partly":[166],"common.":[168]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-07-22T00:00:00"}