{"id":"https://openalex.org/W2473490107","doi":null,"title":"Early improvement of left ventricular function during caloric restriction in obesity.","display_name":"Early improvement of left ventricular function during caloric restriction in obesity.","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W2473490107","mag":"2473490107","pmid":"https://pubmed.ncbi.nlm.nih.gov/3804560"},"language":"en","primary_location":{"id":"pmid:3804560","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3804560","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of obesity","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112191287","display_name":"Francesco Caviezel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F Caviezel","raw_affiliation_strings":["University of Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Milan","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090370201","display_name":"Alberto Margonato","orcid":"https://orcid.org/0000-0003-2673-1031","observed_orcids":["https://orcid.org/0000-0003-2673-1031"]},"institutions":[{"id":"https://openalex.org/I4210133214","display_name":"IRCCS Ospedale San Raffaele","ror":"https://ror.org/039zxt351","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210133214","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Margonato","raw_affiliation_strings":["IRCCS Ospedale San Raffaele"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Ospedale San Raffaele","institution_ids":["https://openalex.org/I4210133214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007971455","display_name":"Giorgio Slaviero","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Slaviero","raw_affiliation_strings":["University of Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Milan","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091370811","display_name":"F Bonetti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Bonetti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075788822","display_name":"Gabriele Vicedomini","orcid":"https://orcid.org/0000-0002-2300-3621","observed_orcids":["https://orcid.org/0000-0002-2300-3621"]},"institutions":[{"id":"https://openalex.org/I4210099239","display_name":"IRCCS Policlinico San Donato","ror":"https://ror.org/01220jp31","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210099239","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Vicedomini","raw_affiliation_strings":["IRCCS Policlinico San Donato"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Policlinico San Donato","institution_ids":["https://openalex.org/I4210099239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076800261","display_name":"Anna Giulia Cattaneo","orcid":"https://orcid.org/0000-0001-5685-3684","observed_orcids":["https://orcid.org/0000-0001-5685-3684"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A G Cattaneo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110847047","display_name":"Gioia Pozza","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Pozza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.48154225,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"10","issue":"6","first_page":"421","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.049800001084804535,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/left-ventricular-function","display_name":"left ventricular function","score":0.906000018119812},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8040000200271606},{"id":"https://openalex.org/keywords/caloric-restriction","display_name":"caloric restriction","score":0.996999979019165},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.8169999718666077},{"id":"https://openalex.org/keywords/systolic-time-intervals","display_name":"systolic time intervals","score":0.9179999828338623},{"id":"https://openalex.org/keywords/pre-ejection-period","display_name":"pre-ejection period","score":0.875},{"id":"https://openalex.org/keywords/exercise-testing","display_name":"exercise testing","score":0.48399999737739563},{"id":"https://openalex.org/keywords/systolic-blood-pressure","display_name":"systolic blood pressure","score":0.8500000238418579},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.902999997138977},{"id":"https://openalex.org/keywords/cardiac-function","display_name":"cardiac function","score":0.6259999871253967}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8979649543762207},{"id":"https://openalex.org/C2781277698","wikidata":"https://www.wikidata.org/wiki/Q861974","display_name":"Dieting","level":4,"score":0.7848718762397766},{"id":"https://openalex.org/C190362976","wikidata":"https://www.wikidata.org/wiki/Q845261","display_name":"Caloric theory","level":2,"score":0.7770625352859497},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5883954167366028},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5602430105209351},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5421794652938843},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5304751992225647},{"id":"https://openalex.org/C2994137971","wikidata":"https://www.wikidata.org/wiki/Q130964","display_name":"Caloric intake","level":3,"score":0.5287613272666931},{"id":"https://openalex.org/C2778345441","wikidata":"https://www.wikidata.org/wiki/Q6460735","display_name":"Meal","level":2,"score":0.5274615287780762},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.4330568313598633},{"id":"https://openalex.org/C111566952","wikidata":"https://www.wikidata.org/wiki/Q1303462","display_name":"Cardiac function curve","level":3,"score":0.4309063255786896},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4276390075683594},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.12164822220802307}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003971","descriptor_name":"Diastole","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005080","descriptor_name":"Exercise Test","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013599","descriptor_name":"Systole","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:3804560","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3804560","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of obesity","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unisr.it:20.500.11768/11937","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/20.500.11768/11937","pdf_url":null,"source":{"id":"https://openalex.org/S7407055348","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 Vita-Salute San Raffaele","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2473490107","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3804560","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2003403155","https://openalex.org/W2144528132","https://openalex.org/W2412202777","https://openalex.org/W2285569212","https://openalex.org/W87834032","https://openalex.org/W2597463069","https://openalex.org/W2900896288","https://openalex.org/W2418167634","https://openalex.org/W2568140817","https://openalex.org/W2500253736"],"abstract_inverted_index":{"Left":[0],"ventricular":[1],"function":[2],"(LVF)":[3],"was":[4],"studied":[5],"in":[6,68,132],"25":[7],"obese":[8],"patients":[9,45],"(four":[10],"males":[11],"and":[12,85,96,102,120],"21":[13],"females)":[14],"by":[15],"serial":[16],"poligraphic":[17],"measurements,":[18],"namely":[19,80],"systolic":[20,98],"time":[21],"intervals":[22],"(STI),":[23],"during":[24,106],"a":[25],"short":[26],"period":[27,82],"of":[28,58,78,118,129],"dieting":[29],"(2721":[30],"kJ/day":[31],"(650":[32],"kcal/day)":[33],"as":[34],"single":[35],"daily":[36],"meal":[37],"regimen).":[38],"In":[39],"the":[40,44,53,56,59,126],"same":[41],"period,":[42],"all":[43],"underwent":[46],"also":[47,109],"three":[48],"standardized":[49],"exercise":[50],"tests":[51],"at":[52],"cycloergometer.":[54],"At":[55],"end":[57],"study":[60],"(20th":[61],"day),":[62],"statistically":[63],"significant":[64],"differences":[65],"were":[66,88,108],"obtained":[67],"weight":[69],"loss":[70],"(P":[71,90],"less":[72,91],"than":[73,92],"0.001);":[74],"two":[75],"main":[76],"parameters":[77],"STI,":[79],"pre-ejection":[81],"index":[83],"(PEPI)":[84],"PEP/LVET":[86],"ratio":[87],"lowered":[89],"0.001):":[93],"furthermore,":[94],"peak":[95],"recovery":[97],"blood":[99],"pressure":[100],"(SBP)":[101],"heart":[103],"rate":[104],"(HR)":[105],"exercising,":[107],"significantly":[110],"reduced.":[111],"These":[112],"data":[113],"suggest":[114],"that":[115],"an":[116],"improvement":[117],"LVF":[119],"cardiac":[121],"performance":[122],"are":[123],"present":[124],"since":[125],"early":[127],"phases":[128],"caloric":[130],"restriction":[131],"obesity.":[133]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-07-22T00:00:00"}