{"id":"https://openalex.org/W2473489829","doi":"https://doi.org/10.1007/978-1-4757-9145-7_100","title":"A Novel Gene Delivery System for Neuroactive Peptides in Brain Tissue","display_name":"A Novel Gene Delivery System for Neuroactive Peptides in Brain Tissue","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W2473489829","doi":"https://doi.org/10.1007/978-1-4757-9145-7_100","mag":"2473489829"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4757-9145-7_100","doi":"https://doi.org/10.1007/978-1-4757-9145-7_100","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4757-9145-7_100","pdf_url":null,"source":{"id":"https://openalex.org/S4210183919","display_name":"Advances in behavioral biology","issn_l":"0099-6246","issn":["0099-6246"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Behavioral Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4255066832","display_name":"Alzheimer\u2019s and Parkinson\u2019s Diseases"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103491448","display_name":"Edwin M. Meyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edwin M. Meyer","raw_affiliation_strings":["Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011122234","display_name":"Ping Wu","orcid":"https://orcid.org/0000-0003-0035-8494","observed_orcids":["https://orcid.org/0000-0003-0035-8494"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ping Wu","raw_affiliation_strings":["Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046313912","display_name":"Mike King","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mike King","raw_affiliation_strings":["Department of Pharmacodynamics College of Pharmacy, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacodynamics College of Pharmacy, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001238775","display_name":"Christopher M. de Fiebre","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher M. de Fiebre","raw_affiliation_strings":["Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053627197","display_name":"William J. Millard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William J. Millard","raw_affiliation_strings":["Department of Neuroscience College of Medicine, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience College of Medicine, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036726100","display_name":"Sean Olof Bryant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sean Bryant","raw_affiliation_strings":["Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028434157","display_name":"Yu-Ping Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu-Ping Gao","raw_affiliation_strings":["Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Therapeutics, University of Florida J. Hillis Miller Health Center, Box 100267, Gainesville, FL, 32610, USA","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I33213144"],"apc_list":null,"apc_paid":null,"fwci":0.4982,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.66410896,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"699","last_page":"707"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-delivery","display_name":"gene delivery","score":0.824999988079071},{"id":"https://openalex.org/keywords/neuropeptides","display_name":"neuropeptides","score":0.902999997138977},{"id":"https://openalex.org/keywords/brain-tissue","display_name":"brain tissue","score":0.953000009059906},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.878000020980835},{"id":"https://openalex.org/keywords/antisense-constructs","display_name":"antisense constructs","score":0.9520000219345093},{"id":"https://openalex.org/keywords/amyloid-precursor-protein","display_name":"amyloid precursor protein","score":0.9869999885559082},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.4819999933242798},{"id":"https://openalex.org/keywords/neurotransmission","display_name":"neurotransmission","score":0.6019999980926514},{"id":"https://openalex.org/keywords/neurotrophic-factors","display_name":"neurotrophic factors","score":0.5220000147819519}],"concepts":[{"id":"https://openalex.org/C2986936838","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Brain tissue","level":2,"score":0.6318314671516418},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5955139398574829},{"id":"https://openalex.org/C31705614","wikidata":"https://www.wikidata.org/wiki/Q423510","display_name":"Amyloid precursor protein","level":4,"score":0.5293850302696228},{"id":"https://openalex.org/C135983454","wikidata":"https://www.wikidata.org/wiki/Q2790163","display_name":"Gene delivery","level":4,"score":0.5111907124519348},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.47574707865715027},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.46972453594207764},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.4612167775630951},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.44686076045036316},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.43216073513031006},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4288583993911743},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.4107879102230072},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3985440731048584},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3880492150783539},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3751353621482849},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3407508134841919},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.328725129365921},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3096635341644287},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.291006863117218},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.2586546540260315},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2358182668685913},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0983324646949768}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4757-9145-7_100","doi":"https://doi.org/10.1007/978-1-4757-9145-7_100","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4757-9145-7_100","pdf_url":null,"source":{"id":"https://openalex.org/S4210183919","display_name":"Advances in behavioral biology","issn_l":"0099-6246","issn":["0099-6246"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Behavioral Biology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1534631025","https://openalex.org/W1677616940","https://openalex.org/W1806895515","https://openalex.org/W1841425779","https://openalex.org/W1842480026","https://openalex.org/W1876368667","https://openalex.org/W1966828982","https://openalex.org/W1982669158","https://openalex.org/W1988057141","https://openalex.org/W2000832493","https://openalex.org/W2022509291","https://openalex.org/W2036264239","https://openalex.org/W2039204610","https://openalex.org/W2045890604","https://openalex.org/W2050627108","https://openalex.org/W2050812642","https://openalex.org/W2059347225","https://openalex.org/W2062636887","https://openalex.org/W2067189573","https://openalex.org/W2076672023","https://openalex.org/W2077468883","https://openalex.org/W2084017165","https://openalex.org/W2085778900","https://openalex.org/W2092700504","https://openalex.org/W2144634347","https://openalex.org/W2157397275","https://openalex.org/W4211260918","https://openalex.org/W4244906151","https://openalex.org/W4323238558"],"related_works":["https://openalex.org/W4415777106","https://openalex.org/W3016790241","https://openalex.org/W7133342052","https://openalex.org/W4281662268","https://openalex.org/W1995801084","https://openalex.org/W4307995219","https://openalex.org/W2602280786","https://openalex.org/W2906882525","https://openalex.org/W1973385841","https://openalex.org/W4417485149"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-07-22T00:00:00"}