{"id":"https://openalex.org/W2473463147","doi":null,"title":"Sustained oscillations of transmembrane Ca2+ fluxes in mitochondria and their possible biological significance.","display_name":"Sustained oscillations of transmembrane Ca2+ fluxes in mitochondria and their possible biological significance.","publication_year":2000,"publication_date":"2000-01-01","ids":{"openalex":"https://openalex.org/W2473463147","mag":"2473463147","pmid":"https://pubmed.ncbi.nlm.nih.gov/11051078"},"language":"en","primary_location":{"id":"pmid:11051078","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11051078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Membrane & cell biology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032889493","display_name":"Y V Evtodienko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210088122","display_name":"Institute of Theoretical and Experimental Biophysics","ror":"https://ror.org/008ebms37","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210088122","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Y V Evtodienko","raw_affiliation_strings":["Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region. evtodienko@venus.iteb.serpukhov.su","Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino Moscow Region"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region. evtodienko@venus.iteb.serpukhov.su","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210088122"]},{"raw_affiliation_string":"Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino Moscow Region","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210088122"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5032889493"],"corresponding_institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210088122"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.22004512,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"14","issue":"1","first_page":"1","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13415","display_name":"Calcium signaling and nucleotide metabolism","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transmembrane-calcium-flux","display_name":"transmembrane calcium flux","score":0.9290000200271606},{"id":"https://openalex.org/keywords/mitochondrial-permeability-transition-pore","display_name":"mitochondrial permeability transition pore","score":0.8460000157356262},{"id":"https://openalex.org/keywords/mitochondrial-matrix-calcium","display_name":"mitochondrial matrix calcium","score":0.8149999976158142},{"id":"https://openalex.org/keywords/phospholipid-peroxidation","display_name":"phospholipid peroxidation","score":0.9419999718666077},{"id":"https://openalex.org/keywords/phospholipid-hydrolysis","display_name":"phospholipid hydrolysis","score":0.9620000123977661},{"id":"https://openalex.org/keywords/calcium-oscillations","display_name":"calcium oscillations","score":0.8569999933242798},{"id":"https://openalex.org/keywords/calcium-wave-propagation","display_name":"calcium wave propagation","score":0.9490000009536743},{"id":"https://openalex.org/keywords/osmotic-shock","display_name":"osmotic shock","score":0.7870000004768372},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9430000185966492},{"id":"https://openalex.org/keywords/mitochondrial-calcium-efflux","display_name":"mitochondrial calcium efflux","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.7680867314338684},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7645747065544128},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.6125543713569641},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.5650198459625244},{"id":"https://openalex.org/C181911157","wikidata":"https://www.wikidata.org/wiki/Q389844","display_name":"Membrane potential","level":2,"score":0.5481590628623962},{"id":"https://openalex.org/C2778439541","wikidata":"https://www.wikidata.org/wiki/Q7106412","display_name":"Oscillation (cell signaling)","level":2,"score":0.4747113287448883},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.4555058479309082},{"id":"https://openalex.org/C75385678","wikidata":"https://www.wikidata.org/wiki/Q4896390","display_name":"Inner mitochondrial membrane","level":3,"score":0.4533675014972687},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.41321560740470886},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28346186876296997},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09206423163414001},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.09040030837059021},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007425","descriptor_name":"Intracellular Membranes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:11051078","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11051078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Membrane & cell biology","raw_type":"Journal Article"},{"id":"mag:2473463147","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11051078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2031621714","https://openalex.org/W2007973190","https://openalex.org/W2046490162","https://openalex.org/W1968480697","https://openalex.org/W2018776448","https://openalex.org/W2325076316","https://openalex.org/W2061678202","https://openalex.org/W24729677","https://openalex.org/W2287136702","https://openalex.org/W2016479661"],"abstract_inverted_index":{"Sustained":[0],"oscillations":[1,25,54,69,113,125],"of":[2,5,23,38,53,59,67,90,129],"transmembrane":[3],"fluxes":[4],"Ca2+":[6,29,94,99,124],"and":[7,35,62,84,96,135],"other":[8],"ions":[9],"in":[10,43,64,77,81,92,97,114],"isolated":[11],"mitochondria":[12,91,107,128],"are":[13,17,55,102,108],"described.":[14],"The":[15,57,104],"data":[16,73,86],"presented":[18],"that":[19,106,123],"the":[20,24,27,32,39,44,51,65,78,85,88,98],"major":[21],"cause":[22],"is":[26,70,117,121],"Ca2+-induced":[28],"efflux":[30],"from":[31,132],"mitochondrial":[33,46,79],"matrix":[34,80],"spontaneous":[36],"opening/closing":[37],"permeability":[40],"transition":[41],"pore":[42],"inner":[45],"membrane.":[47],"Conditions":[48],"favourable":[49],"for":[50],"generation":[52,66],"considered.":[56],"role":[58],"phospholipid":[60],"peroxidation":[61],"hydrolysis":[63],"[Ca2+]":[68,75,112],"emphasized.":[71],"Literature":[72],"concerning":[74],"changes":[76],"intact":[82,115],"cells":[83,116,131],"on":[87],"participation":[89],"intracellular":[93],"oscillation":[95],"wave":[100],"propagation":[101],"reviewed.":[103],"hypothesis":[105],"able":[109],"to":[110],"generate":[111],"put":[118],"forward.":[119],"It":[120],"assumed":[122],"can":[126],"protect":[127],"resting":[130],"osmotic":[133],"shock":[134],"oxidative":[136],"stress.":[137]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-07-22T00:00:00"}