{"id":"https://openalex.org/W2473405668","doi":"https://doi.org/10.1118/1.4958268","title":"TH\u2010EF\u2010BRA\u201011: Feasibility of Super\u2010Resolution Time\u2010Resolved 4DMRI for Multi\u2010Breath Volumetric Motion Simulation in Radiotherapy Planning","display_name":"TH\u2010EF\u2010BRA\u201011: Feasibility of Super\u2010Resolution Time\u2010Resolved 4DMRI for Multi\u2010Breath Volumetric Motion Simulation in Radiotherapy Planning","publication_year":2016,"publication_date":"2016-06-01","ids":{"openalex":"https://openalex.org/W2473405668","doi":"https://doi.org/10.1118/1.4958268","mag":"2473405668"},"language":"en","primary_location":{"id":"doi:10.1118/1.4958268","doi":"https://doi.org/10.1118/1.4958268","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.4958268","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110044275","display_name":"G Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G Li","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101428622","display_name":"Jie Wei","orcid":"https://orcid.org/0000-0003-1781-6412","observed_orcids":["https://orcid.org/0000-0003-1781-6412","https://orcid.org/0000-0003-2987-138X"]},"institutions":[{"id":"https://openalex.org/I125687163","display_name":"City College of New York","ror":"https://ror.org/00wmhkr98","country_code":"US","type":"education","lineage":["https://openalex.org/I125687163"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Wei","raw_affiliation_strings":["City College of New York, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"City College of New York, New York, NY","institution_ids":["https://openalex.org/I125687163"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059124819","display_name":"Kristen L. Zakian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K Zakian","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078382635","display_name":"Margie A. Hunt","orcid":"https://orcid.org/0000-0003-4334-4260","observed_orcids":["https://orcid.org/0000-0003-4334-4260"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Hunt","raw_affiliation_strings":["Mem Sloan-Kettering Cancer Ctr, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mem Sloan-Kettering Cancer Ctr, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026159944","display_name":"Joseph O. Deasy","orcid":"https://orcid.org/0000-0002-9437-266X","observed_orcids":["https://orcid.org/0000-0002-9437-266X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Deasy","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13942029,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"43","issue":"6Part47","first_page":"3899","last_page":"3900"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.019899999722838402,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/time-resolved-mri","display_name":"time-resolved MRI","score":0.902999997138977},{"id":"https://openalex.org/keywords/respiratory-motion","display_name":"respiratory motion","score":0.6610000133514404},{"id":"https://openalex.org/keywords/deformable-image-registration","display_name":"deformable image registration","score":0.843999981880188},{"id":"https://openalex.org/keywords/free-breathing-mri","display_name":"free-breathing MRI","score":0.6710000038146973},{"id":"https://openalex.org/keywords/breath-hold-mri","display_name":"breath-hold MRI","score":0.9610000252723694},{"id":"https://openalex.org/keywords/radiotherapy-treatment-planning","display_name":"radiotherapy treatment planning","score":0.9290000200271606},{"id":"https://openalex.org/keywords/demons-registration","display_name":"demons registration","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C54170458","wikidata":"https://www.wikidata.org/wiki/Q663554","display_name":"Voxel","level":2,"score":0.8211512565612793},{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.5875015258789062},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.5814028978347778},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5561643838882446},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.49107885360717773},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.4795401096343994},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4738633632659912},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4466964602470398},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.44643861055374146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2617315649986267},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.15444186329841614}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1118/1.4958268","doi":"https://doi.org/10.1118/1.4958268","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.4958268","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2588414402","https://openalex.org/W4401574909","https://openalex.org/W4403787102","https://openalex.org/W3012543301","https://openalex.org/W2043182646","https://openalex.org/W4401575118","https://openalex.org/W2108743063","https://openalex.org/W2939722840","https://openalex.org/W2979378685","https://openalex.org/W2805136501"],"abstract_inverted_index":{"Purpose:":[0],"To":[1],"develop":[2],"a":[3,31,45,85,170,174,261],"novel":[4],"super\u2010resolution":[5,25,136,251],"time\u2010resolved":[6,26,252],"4DMRI":[7,28,149,213,253],"technique":[8,254],"to":[9,106,134,186,274,279,296],"evaluate":[10],"multi\u2010breath,":[11],"irregular":[12],"and":[13,94,150,153,173,181,200,211,221,290],"complex":[14],"organ":[15],"motion":[16,108,176,266],"without":[17],"respiratory":[18],"surrogate":[19],"for":[20,264],"radiotherapy":[21],"planning.":[22],"Methods:":[23],"The":[24,65,110,160,205,233,250],"(TR)":[27],"approach":[29],"combines":[30],"series":[32],"of":[33,72,116,162,237],"low\u2010resolution":[34,280],"3D":[35,66,151,164,209,234],"cine":[36,67,152,165,210,235],"MRI":[37,193],"images":[38,68,146,166,202,224,236,278],"acquired":[39,82,120],"during":[40],"free":[41],"breathing":[42],"(FB)":[43],"with":[44,69,113,229,245],"high\u2010resolution":[46,276,286],"breath\u2010hold":[47],"(BH)":[48],"3DMRI":[49],"via":[50,258],"deformable":[51],"image":[52,112],"registration":[53],"(DIR).":[54],"Five":[55],"volunteers":[56],"participated":[57],"in":[58,102,218,302],"the":[59,103,122,163,191,222,238,306],"study":[60,300],"under":[61],"an":[62],"IRB\u2010approved":[63],"protocol.":[64],"voxel":[70,114,158,187,206],"size":[71,115],"5\u00d75\u00d75":[73],"mm3":[74,118],"at":[75],"two":[76],"volumes":[77],"per":[78],"second":[79],"(2Hz)":[80],"were":[81],"coronally":[83],"using":[84,121,144,156,169,190],"T1":[86],"fast":[87],"field":[88],"echo":[89],"sequence,":[90,195],"half\u2010scan":[91],"(0.8)":[92],"acceleration,":[93],"SENSE":[95],"(3)":[96],"parallel":[97],"imaging.":[98],"Phase\u2010encoding":[99],"was":[100,119,132,141,167],"set":[101],"lateral":[104],"direction":[105],"minimize":[107],"artifacts.":[109,248],"BH":[111,201,277],"2\u00d72\u00d72":[117],"same":[123,192],"sequence":[124],"within":[125],"10":[126],"seconds.":[127],"A":[128],"demons\u2010based":[129],"DIR":[130,197,269],"program":[131],"employed":[133],"produce":[135],"2Hz":[137,284],"4DMRI.":[138,287],"Registration":[139],"quality":[140],"visually":[142],"assessed":[143,155,168],"difference":[145,223],"between":[147,198,208],"TR":[148,212],"quantitatively":[154],"average":[157],"correlation.":[159],"fidelity":[161],"gel":[171,240],"phantom":[172,241],"1D":[175],"platform":[177],"by":[178,305],"comparing":[179],"mobile":[180,239],"static":[182],"images.":[183],"Results:":[184],"Owing":[185],"intensity":[188],"similarity":[189],"scanning":[194,247],"accurate":[196],"FB":[199,281],"is":[203,301],"achieved.":[204],"correlations":[207],"are":[214,292],"greater":[215],"than":[216],"0.92":[217],"all":[219],"cases":[220],"illustrate":[225],"minimal":[226,246],"residual":[227],"error":[228],"little":[230],"systematic":[231],"patterns.":[232],"preserve":[242],"object":[243],"geometry":[244],"Conclusion:":[249],"has":[255,271],"been":[256,272],"achieved":[257,273],"DIR,":[259],"providing":[260],"potential":[262],"solution":[263],"multi\u2010breath":[265],"assessment.":[267],"Accurate":[268],"mapping":[270],"map":[275],"images,":[282],"producing":[283],"volumetric":[285],"Further":[288],"validation":[289],"improvement":[291],"still":[293],"required":[294],"prior":[295],"clinical":[297],"applications.":[298],"This":[299],"part":[303],"supported":[304],"NIH":[307],"(U54CA137788/U54CA132378).":[308]},"counts_by_year":[],"updated_date":"2026-09-24T07:57:37.273135","created_date":"2016-07-22T00:00:00"}