{"id":"https://openalex.org/W2473145116","doi":null,"title":"Chronic exercise increases sensitivity to the conditioned rewarding effects of cocaine.","display_name":"Chronic exercise increases sensitivity to the conditioned rewarding effects of cocaine.","publication_year":2008,"publication_date":"2008-07-01","ids":{"openalex":"https://openalex.org/W2473145116","mag":"2473145116","pmid":"https://pubmed.ncbi.nlm.nih.gov/18799826","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3867018"},"language":"en","primary_location":{"id":"pmid:18799826","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18799826","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacological reports : PR","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3867018","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068894138","display_name":"Mark A. Smith","orcid":"https://orcid.org/0000-0002-0429-2798","observed_orcids":["https://orcid.org/0000-0002-0429-2798"]},"institutions":[{"id":"https://openalex.org/I141720752","display_name":"Davidson College","ror":"https://ror.org/02f7k4z58","country_code":"US","type":"education","lineage":["https://openalex.org/I141720752"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark A Smith","raw_affiliation_strings":["Department of Psychology and Program in Neuroscience, Davidson College, Davidson, NC 28035-7037, USA. masmith@davidson.edu","Department of Psychology and Program in Neuroscience, Davidson College, Davidson, NC 28035-7037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology and Program in Neuroscience, Davidson College, Davidson, NC 28035-7037, USA. masmith@davidson.edu","institution_ids":["https://openalex.org/I141720752"]},{"raw_affiliation_string":"Department of Psychology and Program in Neuroscience, Davidson College, Davidson, NC 28035-7037, USA","institution_ids":["https://openalex.org/I141720752"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026677244","display_name":"Samantha R. Gergans","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Samantha R Gergans","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083024568","display_name":"Jordan C. Iordanou","orcid":"https://orcid.org/0000-0002-1928-0167","observed_orcids":["https://orcid.org/0000-0002-1928-0167"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jordan C Iordanou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103548795","display_name":"Megan A. Lyle","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Megan A Lyle","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4991,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.56790192,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"60","issue":"4","first_page":"561","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exercise-training","display_name":"exercise training","score":0.996999979019165},{"id":"https://openalex.org/keywords/cocaine","display_name":"cocaine","score":0.949999988079071},{"id":"https://openalex.org/keywords/conditioned-place-preference","display_name":"conditioned place preference","score":0.9549999833106995},{"id":"https://openalex.org/keywords/drug-reward","display_name":"drug reward","score":0.5139999985694885},{"id":"https://openalex.org/keywords/sedentary-behavior","display_name":"sedentary behavior","score":0.6290000081062317},{"id":"https://openalex.org/keywords/female-rats","display_name":"female rats","score":0.6629999876022339},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.38199999928474426}],"concepts":[{"id":"https://openalex.org/C35124327","wikidata":"https://www.wikidata.org/wiki/Q5159285","display_name":"Conditioned place preference","level":3,"score":0.7398677468299866},{"id":"https://openalex.org/C2780655333","wikidata":"https://www.wikidata.org/wiki/Q333203","display_name":"Weaning","level":2,"score":0.5378197431564331},{"id":"https://openalex.org/C2781249084","wikidata":"https://www.wikidata.org/wiki/Q908656","display_name":"Preference","level":2,"score":0.49508705735206604},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4860256314277649},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44099345803260803},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4101666808128357},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3021756410598755},{"id":"https://openalex.org/C2777389121","wikidata":"https://www.wikidata.org/wiki/Q81225","display_name":"Morphine","level":2,"score":0.07801413536071777},{"id":"https://openalex.org/C175444787","wikidata":"https://www.wikidata.org/wiki/Q39072","display_name":"Microeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003042","descriptor_name":"Cocaine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003042","descriptor_name":"Cocaine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003216","descriptor_name":"Conditioning, Operant","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012201","descriptor_name":"Reward","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018765","descriptor_name":"Dopamine Uptake Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D018765","descriptor_name":"Dopamine Uptake Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D020318","descriptor_name":"Rats, Long-Evans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmid:18799826","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18799826","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacological reports : PR","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2851197","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3867018","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3867018","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3867018/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Pharmacol Rep","raw_type":"Text"},{"id":"mag:2473145116","doi":null,"is_oa":false,"landing_page_url":"http://www.if-pan.krakow.pl/pjp/pdf/2008/4_561.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S180401253","display_name":"Pharmacological Reports","issn_l":"1734-1140","issn":["1734-1140","2299-5684"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Pharmacological Reports","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2851197","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3867018","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8504866575","display_name":"Social and Enviromental Influences on Opioid Sensitivity","funder_award_id":"R15DA014255","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"}],"funders":[{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1768834600","https://openalex.org/W1819264397","https://openalex.org/W1913760354","https://openalex.org/W1980618099","https://openalex.org/W2000696407","https://openalex.org/W2003412165","https://openalex.org/W2021066060","https://openalex.org/W2049768701","https://openalex.org/W2049981427","https://openalex.org/W2054047875","https://openalex.org/W2058868791","https://openalex.org/W2059537506","https://openalex.org/W2059567897","https://openalex.org/W2069325625","https://openalex.org/W2072630058","https://openalex.org/W2080970664","https://openalex.org/W2084445735","https://openalex.org/W2105999601","https://openalex.org/W4321429251"],"related_works":["https://openalex.org/W2163024301","https://openalex.org/W2131004597","https://openalex.org/W2140837625","https://openalex.org/W2002629369","https://openalex.org/W2275219801","https://openalex.org/W2090912640","https://openalex.org/W2802198850","https://openalex.org/W1992235968","https://openalex.org/W2046235071","https://openalex.org/W1590727693"],"abstract_inverted_index":{"The":[0],"purpose":[1],"of":[2,18,43,63,88,103],"this":[3,76,79],"study":[4],"was":[5,81],"to":[6,13,29,73,98],"determine":[7],"whether":[8],"chronic":[9,94],"exercise":[10,33,95],"alters":[11],"sensitivity":[12,97],"the":[14,41,48,85,99],"conditioned":[15,49,57,100],"rewarding":[16,101],"effects":[17,42,102],"cocaine.":[19,89,104],"Female":[20],"rats":[21,66,72],"were":[22,45,67],"obtained":[23],"at":[24,84],"weaning":[25],"and":[26,78],"randomly":[27],"assigned":[28],"either":[30],"sedentary":[31,71],"or":[32],"conditions.":[34],"After":[35],"6":[36],"weeks":[37],"under":[38],"these":[39],"conditions,":[40],"cocaine":[44,74],"examined":[46],"in":[47,60,75],"place":[50,58],"preference":[51,59],"procedure.":[52],"Cocaine":[53],"produced":[54],"a":[55],"dose-dependent":[56],"both":[61],"groups":[62],"rats.":[64],"Exercising":[65],"more":[68],"sensitive":[69],"than":[70],"procedure,":[77],"effect":[80],"most":[82],"pronounced":[83],"highest":[86],"dose":[87],"These":[90],"data":[91],"suggest":[92],"that":[93],"increases":[96]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-07-22T00:00:00"}