{"id":"https://openalex.org/W2473045695","doi":"https://doi.org/10.1016/j.bpj.2015.11.1833","title":"Dynamic Stabilization of Expressed Proteins in Engineered Diatom Biosilica","display_name":"Dynamic Stabilization of Expressed Proteins in Engineered Diatom Biosilica","publication_year":2016,"publication_date":"2016-02-01","ids":{"openalex":"https://openalex.org/W2473045695","doi":"https://doi.org/10.1016/j.bpj.2015.11.1833","mag":"2473045695"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpj.2015.11.1833","doi":"https://doi.org/10.1016/j.bpj.2015.11.1833","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2015.11.1833","pdf_url":"http://www.cell.com/article/S0006349515030167/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0006349515030167/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007996234","display_name":"Yijia Xiong","orcid":"https://orcid.org/0000-0002-9832-1472","observed_orcids":["https://orcid.org/0000-0002-9832-1472"]},"institutions":[{"id":"https://openalex.org/I93393672","display_name":"Western University of Health Sciences","ror":"https://ror.org/05167c961","country_code":"US","type":"education","lineage":["https://openalex.org/I93393672"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yijia Xiong","raw_affiliation_strings":["Basic Medical Sciences, Western University of Health Sciences, Lebanon, OR, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basic Medical Sciences, Western University of Health Sciences, Lebanon, OR, USA","institution_ids":["https://openalex.org/I93393672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043698827","display_name":"Nicole R. Ford","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole R. Ford","raw_affiliation_strings":["Marine Biotechnology Group, Pacific Northwest National Laboratory, Sequim, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Biotechnology Group, Pacific Northwest National Laboratory, Sequim, WA, USA","institution_ids":["https://openalex.org/I142606810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016455680","display_name":"Karen A. Hecht","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen A. Hecht","raw_affiliation_strings":["Marine Biotechnology Group, Pacific Northwest National Laboratory, Sequim, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Biotechnology Group, Pacific Northwest National Laboratory, Sequim, WA, USA","institution_ids":["https://openalex.org/I142606810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055453612","display_name":"Guritno Roesijadi","orcid":"https://orcid.org/0000-0001-5479-4596","observed_orcids":["https://orcid.org/0000-0001-5479-4596"]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guritno Roesijadi","raw_affiliation_strings":["Marine Biotechnology Group, Pacific Northwest National Laboratory, Sequim, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Biotechnology Group, Pacific Northwest National Laboratory, Sequim, WA, USA","institution_ids":["https://openalex.org/I142606810"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034507169","display_name":"Thomas C. Squier","orcid":"https://orcid.org/0000-0003-0735-3194","observed_orcids":["https://orcid.org/0000-0003-0735-3194"]},"institutions":[{"id":"https://openalex.org/I93393672","display_name":"Western University of Health Sciences","ror":"https://ror.org/05167c961","country_code":"US","type":"education","lineage":["https://openalex.org/I93393672"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas C. Squier","raw_affiliation_strings":["Basic Medical Sciences, Western University of Health Sciences, Lebanon, OR, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basic Medical Sciences, Western University of Health Sciences, Lebanon, OR, USA","institution_ids":["https://openalex.org/I93393672"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05908896,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"110","issue":"3","first_page":"341a","last_page":"341a"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12012","display_name":"Diatoms and Algae Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12012","display_name":"Diatoms and Algae Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diatom-biosilica","display_name":"diatom biosilica","score":0.8500000238418579},{"id":"https://openalex.org/keywords/thalassiosira-pseudonana","display_name":"Thalassiosira pseudonana","score":0.9330000281333923},{"id":"https://openalex.org/keywords/protein-immobilization","display_name":"protein immobilization","score":0.7549999952316284},{"id":"https://openalex.org/keywords/scfv-antibodies","display_name":"scFv antibodies","score":0.7020000219345093},{"id":"https://openalex.org/keywords/trinitrotoluene-detection","display_name":"trinitrotoluene detection","score":0.8550000190734863},{"id":"https://openalex.org/keywords/enhanced-green-fluorescent-protein","display_name":"enhanced green fluorescent protein","score":0.8209999799728394},{"id":"https://openalex.org/keywords/frustule","display_name":"frustule","score":0.7649999856948853},{"id":"https://openalex.org/keywords/self-assembly","display_name":"self-assembly","score":0.6819999814033508},{"id":"https://openalex.org/keywords/protein-stability","display_name":"protein stability","score":0.4059999883174896},{"id":"https://openalex.org/keywords/biosensor-materials","display_name":"biosensor materials","score":0.4129999876022339}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7360064387321472},{"id":"https://openalex.org/C2778114769","wikidata":"https://www.wikidata.org/wiki/Q3089359","display_name":"Frustule","level":3,"score":0.6980888843536377},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.6282902359962463},{"id":"https://openalex.org/C142613039","wikidata":"https://www.wikidata.org/wiki/Q272983","display_name":"Green fluorescent protein","level":3,"score":0.6076179146766663},{"id":"https://openalex.org/C147816474","wikidata":"https://www.wikidata.org/wiki/Q169525","display_name":"Protein engineering","level":3,"score":0.5655754804611206},{"id":"https://openalex.org/C102362939","wikidata":"https://www.wikidata.org/wiki/Q417062","display_name":"Chaotropic agent","level":2,"score":0.523825466632843},{"id":"https://openalex.org/C2779260011","wikidata":"https://www.wikidata.org/wiki/Q412287","display_name":"mCherry","level":4,"score":0.5230570435523987},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.5133146643638611},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5092943906784058},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.16978847980499268},{"id":"https://openalex.org/C2778902744","wikidata":"https://www.wikidata.org/wiki/Q162678","display_name":"Diatom","level":2,"score":0.15048211812973022},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1354677975177765},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10178890824317932},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bpj.2015.11.1833","doi":"https://doi.org/10.1016/j.bpj.2015.11.1833","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2015.11.1833","pdf_url":"http://www.cell.com/article/S0006349515030167/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bpj.2015.11.1833","doi":"https://doi.org/10.1016/j.bpj.2015.11.1833","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2015.11.1833","pdf_url":"http://www.cell.com/article/S0006349515030167/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2473045695.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2346579734","https://openalex.org/W2226382113","https://openalex.org/W2766671507","https://openalex.org/W2105653748","https://openalex.org/W4403542699","https://openalex.org/W2598816767","https://openalex.org/W2583865651","https://openalex.org/W3000732919","https://openalex.org/W2943538495","https://openalex.org/W2980034803"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-07-22T00:00:00"}