{"id":"https://openalex.org/W2472425284","doi":"https://doi.org/10.1016/j.lfs.2016.06.019","title":"Inducible nitric oxide inhibitor aminoguanidine, ameliorates deleterious effects of lipopolysaccharide on memory and long term potentiation in rat","display_name":"Inducible nitric oxide inhibitor aminoguanidine, ameliorates deleterious effects of lipopolysaccharide on memory and long term potentiation in rat","publication_year":2016,"publication_date":"2016-06-25","ids":{"openalex":"https://openalex.org/W2472425284","doi":"https://doi.org/10.1016/j.lfs.2016.06.019","mag":"2472425284","pmid":"https://pubmed.ncbi.nlm.nih.gov/27341994"},"language":"en","primary_location":{"id":"doi:10.1016/j.lfs.2016.06.019","doi":"https://doi.org/10.1016/j.lfs.2016.06.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.lfs.2016.06.019","pdf_url":null,"source":{"id":"https://openalex.org/S175775512","display_name":"Life Sciences","issn_l":"0024-3205","issn":["0024-3205","1879-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005277756","display_name":"Akbar Anaeigoudari","orcid":"https://orcid.org/0000-0002-1422-393X","observed_orcids":["https://orcid.org/0000-0002-1422-393X"]},"institutions":[{"id":"https://openalex.org/I1280764379","display_name":"University of Jiroft","ror":"https://ror.org/00mz6ad23","country_code":"IR","type":"education","lineage":["https://openalex.org/I1280764379"]},{"id":"https://openalex.org/I4405281540","display_name":"Jiroft University of Medical Sciences","ror":"https://ror.org/04gy83161","country_code":"IR","type":"education","lineage":["https://openalex.org/I4405281540"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Akbar Anaeigoudari","raw_affiliation_strings":["Department of Physiology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran","institution_ids":["https://openalex.org/I1280764379","https://openalex.org/I4405281540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050273143","display_name":"Mohammad Soukhtanloo","orcid":"https://orcid.org/0000-0003-2145-125X","observed_orcids":["https://orcid.org/0000-0003-2145-125X"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Soukhtanloo","raw_affiliation_strings":["Department of Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran","institution_ids":["https://openalex.org/I165560825"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082924880","display_name":"Parham Reisi","orcid":"https://orcid.org/0000-0002-7552-4680","observed_orcids":["https://orcid.org/0000-0002-7552-4680"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Parham Reisi","raw_affiliation_strings":["Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042901205","display_name":"Farimah Beheshti","orcid":"https://orcid.org/0000-0003-1524-2339","observed_orcids":["https://orcid.org/0000-0003-1524-2339"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Farimah Beheshti","raw_affiliation_strings":["Neurogenic Inflammation Research Center and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurogenic Inflammation Research Center and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran","institution_ids":["https://openalex.org/I165560825"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081215156","display_name":"Mahmoud Hosseini","orcid":"https://orcid.org/0000-0001-6425-5123","observed_orcids":["https://orcid.org/0000-0001-6425-5123","https://orcid.org/0000-0002-9843-3394"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Mahmoud Hosseini","raw_affiliation_strings":["Neurocognitive Research Center and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurocognitive Research Center and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran","institution_ids":["https://openalex.org/I165560825"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5081215156"],"corresponding_institution_ids":["https://openalex.org/I165560825"],"apc_list":{"value":3810,"currency":"USD","value_usd":3810},"apc_paid":null,"fwci":4.9299,"has_fulltext":false,"cited_by_count":69,"citation_normalized_percentile":{"value":0.9542841,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"158","issue":null,"first_page":"22","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.9355000257492065,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.9355000257492065,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.016599999740719795,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.012000000104308128,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aminoguanidine","display_name":"aminoguanidine","score":0.9739999771118164},{"id":"https://openalex.org/keywords/inducible-nitric-oxide-synthase-inhibition","display_name":"inducible nitric oxide synthase inhibition","score":0.8949999809265137},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.8759999871253967},{"id":"https://openalex.org/keywords/lipopolysaccharide","display_name":"lipopolysaccharide","score":0.996999979019165},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.9769999980926514},{"id":"https://openalex.org/keywords/memory-impairment","display_name":"memory impairment","score":0.843999981880188},{"id":"https://openalex.org/keywords/long-term-potentiation","display_name":"long-term potentiation","score":0.9559999704360962},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.7870000004768372},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9789999723434448},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.7369999885559082},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.8180000185966492},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9160000085830688},{"id":"https://openalex.org/keywords/learning-and-memory","display_name":"learning and memory","score":0.574999988079071}],"concepts":[{"id":"https://openalex.org/C25274449","wikidata":"https://www.wikidata.org/wiki/Q1805481","display_name":"Long-term potentiation","level":3,"score":0.9369202852249146},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.8174020051956177},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.6328959465026855},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5570670366287231},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5414490699768066},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.5237172245979309},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.48139524459838867},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2390194535255432},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2373267412185669},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23499330878257751},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22166889905929565},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.05904793739318848},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006146","descriptor_name":"Guanidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008315","descriptor_name":"Malondialdehyde","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D019706","descriptor_name":"Excitatory Postsynaptic Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052247","descriptor_name":"Nitric Oxide Synthase Type II","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.lfs.2016.06.019","doi":"https://doi.org/10.1016/j.lfs.2016.06.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.lfs.2016.06.019","pdf_url":null,"source":{"id":"https://openalex.org/S175775512","display_name":"Life Sciences","issn_l":"0024-3205","issn":["0024-3205","1879-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life Sciences","raw_type":"journal-article"},{"id":"pmid:27341994","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27341994","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8399740117","display_name":null,"funder_award_id":"921568","funder_id":"https://openalex.org/F4320322855","funder_display_name":"Mashhad University of Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320322855","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W191793640","https://openalex.org/W194801233","https://openalex.org/W1506745757","https://openalex.org/W1546852035","https://openalex.org/W1558869300","https://openalex.org/W1561059599","https://openalex.org/W1607892649","https://openalex.org/W1733395966","https://openalex.org/W1911139940","https://openalex.org/W1966073374","https://openalex.org/W1974966491","https://openalex.org/W1975677874","https://openalex.org/W1977427213","https://openalex.org/W1983915057","https://openalex.org/W1984863334","https://openalex.org/W1985333845","https://openalex.org/W1990930862","https://openalex.org/W1994009282","https://openalex.org/W2000996522","https://openalex.org/W2001900724","https://openalex.org/W2003026610","https://openalex.org/W2006819627","https://openalex.org/W2007452107","https://openalex.org/W2007510319","https://openalex.org/W2012992792","https://openalex.org/W2014006342","https://openalex.org/W2015663762","https://openalex.org/W2023136593","https://openalex.org/W2023559607","https://openalex.org/W2035139640","https://openalex.org/W2036695525","https://openalex.org/W2037416030","https://openalex.org/W2040506111","https://openalex.org/W2046055108","https://openalex.org/W2051061580","https://openalex.org/W2054326893","https://openalex.org/W2058302603","https://openalex.org/W2073170210","https://openalex.org/W2087544157","https://openalex.org/W2089024181","https://openalex.org/W2092756896","https://openalex.org/W2093895802","https://openalex.org/W2094759938","https://openalex.org/W2101116833","https://openalex.org/W2103411291","https://openalex.org/W2108772424","https://openalex.org/W2119126576","https://openalex.org/W2119487571","https://openalex.org/W2127614776","https://openalex.org/W2132573038","https://openalex.org/W2136637511","https://openalex.org/W2138215031","https://openalex.org/W2142234953","https://openalex.org/W2145367523","https://openalex.org/W2158221809","https://openalex.org/W2159446195","https://openalex.org/W2283508593","https://openalex.org/W2333809409","https://openalex.org/W2342356818","https://openalex.org/W2343827751"],"related_works":["https://openalex.org/W1914536245","https://openalex.org/W2223308719","https://openalex.org/W2037416030","https://openalex.org/W2000996522","https://openalex.org/W1462959463","https://openalex.org/W3030915132","https://openalex.org/W4399135676","https://openalex.org/W2702374653","https://openalex.org/W2896784416","https://openalex.org/W2755900475"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-07-22T00:00:00"}