{"id":"https://openalex.org/W2471362283","doi":"https://doi.org/10.15407/animbiol18.02.152","title":"DEVELOPMENT OF TECHNOLOGY OF BLOOD COAGULATION FACTOR VIII PURIFICATION BY THE METHOD OF AFFINITY CHROMATOGRAPHY ON SILICA SORBENTS","display_name":"DEVELOPMENT OF TECHNOLOGY OF BLOOD COAGULATION FACTOR VIII PURIFICATION BY THE METHOD OF AFFINITY CHROMATOGRAPHY ON SILICA SORBENTS","publication_year":2016,"publication_date":"2016-07-01","ids":{"openalex":"https://openalex.org/W2471362283","doi":"https://doi.org/10.15407/animbiol18.02.152","mag":"2471362283"},"language":"en","primary_location":{"id":"doi:10.15407/animbiol18.02.152","doi":"https://doi.org/10.15407/animbiol18.02.152","is_oa":true,"landing_page_url":"https://doi.org/10.15407/animbiol18.02.152","pdf_url":"http://aminbiol.com.ua/20162pdf/19.pdf","source":{"id":"https://openalex.org/S4210202773","display_name":"The Animal Biology","issn_l":"1681-0015","issn":["1681-0015","2313-2191"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Animal Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://aminbiol.com.ua/20162pdf/19.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002061197","display_name":"N. Shurko","orcid":"https://orcid.org/0000-0003-3224-8679","observed_orcids":["https://orcid.org/0000-0003-3224-8679"]},"institutions":[{"id":"https://openalex.org/I103187081","display_name":"Smithsonian Institution","ror":"https://ror.org/01pp8nd67","country_code":"US","type":"government","lineage":["https://openalex.org/I103187081"]},{"id":"https://openalex.org/I4210109983","display_name":"Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/017wx6w12","country_code":"UA","type":"facility","lineage":["https://openalex.org/I4210109983","https://openalex.org/I4210144782"]},{"id":"https://openalex.org/I4210144782","display_name":"National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/042dnf796","country_code":"UA","type":"government","lineage":["https://openalex.org/I4210144782"]}],"countries":["UA","US"],"is_corresponding":false,"raw_author_name":"N. O. Shurko","raw_affiliation_strings":["Institute of Blood Pathology and Transfusion Medicine NAMS of Ukraine\u00bb , 45 gen. Chuprynky str. , Lviv 79044 , Ukraine,","SI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Blood Pathology and Transfusion Medicine NAMS of Ukraine\u00bb , 45 gen. Chuprynky str. , Lviv 79044 , Ukraine,","institution_ids":["https://openalex.org/I4210109983","https://openalex.org/I4210144782"]},{"raw_affiliation_string":"SI","institution_ids":["https://openalex.org/I103187081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090083446","display_name":"T. Danysh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109983","display_name":"Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/017wx6w12","country_code":"UA","type":"facility","lineage":["https://openalex.org/I4210109983","https://openalex.org/I4210144782"]},{"id":"https://openalex.org/I4210144782","display_name":"National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/042dnf796","country_code":"UA","type":"government","lineage":["https://openalex.org/I4210144782"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"T. V. Danysh","raw_affiliation_strings":["Institute of Blood Pathology and Transfusion Medicine NAMS of Ukraine\u00bb , 45 gen. Chuprynky str. , Lviv 79044 , Ukraine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Blood Pathology and Transfusion Medicine NAMS of Ukraine\u00bb , 45 gen. Chuprynky str. , Lviv 79044 , Ukraine,","institution_ids":["https://openalex.org/I4210109983","https://openalex.org/I4210144782"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1500,"currency":"UAH","value_usd":null},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"2","first_page":"152","last_page":"159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.0778999999165535,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/factor-viii","display_name":"factor VIII","score":0.8270000219345093},{"id":"https://openalex.org/keywords/affinity-chromatography","display_name":"affinity chromatography","score":0.925000011920929},{"id":"https://openalex.org/keywords/silica-sorbent","display_name":"silica sorbent","score":0.9890000224113464},{"id":"https://openalex.org/keywords/protein-purification","display_name":"protein purification","score":0.8339999914169312}],"concepts":[{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.7391210794448853},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6857749819755554},{"id":"https://openalex.org/C179247698","wikidata":"https://www.wikidata.org/wiki/Q382799","display_name":"Affinity chromatography","level":3,"score":0.611151933670044},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47631439566612244},{"id":"https://openalex.org/C2779532046","wikidata":"https://www.wikidata.org/wiki/Q308976","display_name":"Silica gel","level":2,"score":0.46081680059432983},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.363536536693573},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13631004095077515},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11502411961555481},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0635899007320404},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.15407/animbiol18.02.152","doi":"https://doi.org/10.15407/animbiol18.02.152","is_oa":true,"landing_page_url":"https://doi.org/10.15407/animbiol18.02.152","pdf_url":"http://aminbiol.com.ua/20162pdf/19.pdf","source":{"id":"https://openalex.org/S4210202773","display_name":"The Animal Biology","issn_l":"1681-0015","issn":["1681-0015","2313-2191"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Animal Biology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.15407/animbiol18.02.152","doi":"https://doi.org/10.15407/animbiol18.02.152","is_oa":true,"landing_page_url":"https://doi.org/10.15407/animbiol18.02.152","pdf_url":"http://aminbiol.com.ua/20162pdf/19.pdf","source":{"id":"https://openalex.org/S4210202773","display_name":"The Animal Biology","issn_l":"1681-0015","issn":["1681-0015","2313-2191"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Animal Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2471362283.pdf","grobid_xml":"https://content.openalex.org/works/W2471362283.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W36240055","https://openalex.org/W572043532","https://openalex.org/W1559966695","https://openalex.org/W1585891024","https://openalex.org/W1625642974","https://openalex.org/W1949172928","https://openalex.org/W1965625390","https://openalex.org/W1997180556","https://openalex.org/W2015533801","https://openalex.org/W2024630021","https://openalex.org/W2033247230","https://openalex.org/W2100837269","https://openalex.org/W2108762904","https://openalex.org/W2138001653","https://openalex.org/W2286481093","https://openalex.org/W4252796859","https://openalex.org/W6699863364","https://openalex.org/W6815242242"],"related_works":["https://openalex.org/W3010576815","https://openalex.org/W2038123685","https://openalex.org/W2298014806","https://openalex.org/W399330331","https://openalex.org/W4243808634","https://openalex.org/W2993620734","https://openalex.org/W98143338","https://openalex.org/W3105049629","https://openalex.org/W4239942014","https://openalex.org/W3023681494"],"abstract_inverted_index":{"\u0421\u0422\u0412\u041e\u0420\u0415\u041d\u041d\u042f":[0],"\u0422\u0415\u0425\u041d\u041e\u041b\u041e\u0413\u0406\u0407":[1],"\u041e\u0422\u0420\u0418\u041c\u0410\u041d\u041d\u042f":[2],"\u0424\u0410\u041a\u0422\u041e\u0420\u0410":[3],"VIII":[4],"\u0417\u0421\u0406\u0414\u0410\u041d\u041d\u042f":[5]},"counts_by_year":[],"updated_date":"2026-09-06T09:10:53.072986","created_date":"2016-07-22T00:00:00"}