{"id":"https://openalex.org/W2470929699","doi":null,"title":"[Management of micro-inflammation in uremia].","display_name":"[Management of micro-inflammation in uremia].","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2470929699","mag":"2470929699","pmid":"https://pubmed.ncbi.nlm.nih.gov/14650756"},"language":"fr","primary_location":{"id":"pmid:14650756","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14650756","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrologie","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071660720","display_name":"Ziad A. Massy","orcid":"https://orcid.org/0000-0001-5771-5996","observed_orcids":["https://orcid.org/0000-0001-5771-5996"]},"institutions":[{"id":"https://openalex.org/I4210096553","display_name":"Centre Hospitalier Universitaire Amiens-Picardie","ror":"https://ror.org/010567a58","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210096553"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Z A Massy","raw_affiliation_strings":["Service de pharmacologie clinique, Service de n\u00e9phrologie, Centre hospitalier universitaire, Amiens. massy@necker.fr","Service de pharmacologie clinique, Service de n\u00e9phrologie, Centre hospitalier universitaire, Amiens"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de pharmacologie clinique, Service de n\u00e9phrologie, Centre hospitalier universitaire, Amiens. massy@necker.fr","institution_ids":["https://openalex.org/I4210096553"]},{"raw_affiliation_string":"Service de pharmacologie clinique, Service de n\u00e9phrologie, Centre hospitalier universitaire, Amiens","institution_ids":["https://openalex.org/I4210096553"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085783572","display_name":"G. Choukroun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Choukroun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"24","issue":"7","first_page":"415","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.7540000081062317},{"id":"https://openalex.org/keywords/uremia","display_name":"uremia","score":0.8080000281333923},{"id":"https://openalex.org/keywords/anti-inflammatory-therapy","display_name":"anti-inflammatory therapy","score":0.8029999732971191},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.9240000247955322},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":1.0},{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":0.9319999814033508},{"id":"https://openalex.org/keywords/inflammation-management","display_name":"inflammation management","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.8911691904067993},{"id":"https://openalex.org/C2776635150","wikidata":"https://www.wikidata.org/wiki/Q13365776","display_name":"Uremia","level":2,"score":0.8382494449615479},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7935286164283752},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.5121805667877197},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.4583022892475128},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3501385748386383},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3084491491317749}],"mesh":[{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D014511","descriptor_name":"Uremia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:14650756","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14650756","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrologie","raw_type":"English Abstract"},{"id":"mag:2470929699","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14650756","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9907000064849854,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1567127662","https://openalex.org/W1978163194","https://openalex.org/W1988226887","https://openalex.org/W2013180282","https://openalex.org/W2041213396","https://openalex.org/W2051580480","https://openalex.org/W2065813468","https://openalex.org/W2070396041","https://openalex.org/W2084676615","https://openalex.org/W2085598380","https://openalex.org/W2107529916","https://openalex.org/W2125195890","https://openalex.org/W2132446707","https://openalex.org/W2134924827","https://openalex.org/W2146460451","https://openalex.org/W2158745632","https://openalex.org/W2164718332","https://openalex.org/W2395289703","https://openalex.org/W2406529774"],"related_works":["https://openalex.org/W59247452","https://openalex.org/W2105234132","https://openalex.org/W2139709054","https://openalex.org/W2121538400","https://openalex.org/W2041083337","https://openalex.org/W2382925827","https://openalex.org/W3194467544","https://openalex.org/W2409557043","https://openalex.org/W2386037867","https://openalex.org/W6994421686"],"abstract_inverted_index":{"Chronic":[0],"micro-inflammation":[1,16,75],"is":[2,28,55,61],"commonly":[3],"observed":[4],"in":[5,47],"patients":[6],"with":[7],"chronic":[8],"renal":[9],"failure.":[10],"However,":[11,53],"the":[12,21],"causes":[13],"of":[14,25],"this":[15],"remain":[17],"mainly":[18],"indeterminated.":[19],"Therefore,":[20],"appropriate":[22],"therapeutic":[23],"management":[24],"uremic":[26,51,74],"microinflammation":[27],"not":[29,62],"yet":[30],"established.":[31],"Meanwhile,":[32],"it":[33,54],"appears":[34],"to":[35,38,49,72],"be":[36],"reasonable":[37],"use":[39],"current":[40],"non-specific":[41],"anti-inflammatory":[42],"therapies":[43],"(e.g.":[44,67],"ACEI,":[45],"statins)":[46],"order":[48],"reduce":[50],"micro-inflammation.":[52],"clear":[56],"that":[57],"such":[58],"an":[59],"approach":[60],"sufficient,":[63],"and":[64],"further":[65],"strategies":[66],"vitamin":[68],"E)":[69],"are":[70],"warranted":[71],"optimize":[73],"prevention.":[76]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-07-22T00:00:00"}