{"id":"https://openalex.org/W2470745271","doi":"https://doi.org/10.1001/jamainternmed.2016.2417","title":"Association of Specific Dietary Fats With Total and Cause-Specific Mortality","display_name":"Association of Specific Dietary Fats With Total and Cause-Specific Mortality","publication_year":2016,"publication_date":"2016-07-05","ids":{"openalex":"https://openalex.org/W2470745271","doi":"https://doi.org/10.1001/jamainternmed.2016.2417","mag":"2470745271","pmid":"https://pubmed.ncbi.nlm.nih.gov/27379574","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5123772"},"language":"en","primary_location":{"id":"doi:10.1001/jamainternmed.2016.2417","doi":"https://doi.org/10.1001/jamainternmed.2016.2417","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamainternmed.2016.2417","pdf_url":"https://jamanetwork.com/journals/jamainternalmedicine/articlepdf/2530902/ioi160037.pdf","source":{"id":"https://openalex.org/S65364685","display_name":"JAMA Internal Medicine","issn_l":"2168-6106","issn":["2168-6106","2168-6114"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Internal Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://jamanetwork.com/journals/jamainternalmedicine/articlepdf/2530902/ioi160037.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090405129","display_name":"Dong D. Wang","orcid":"https://orcid.org/0000-0002-0897-3048","observed_orcids":["https://orcid.org/0000-0002-0897-3048"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dong D. Wang","raw_affiliation_strings":["Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100385634","display_name":"Yanping Li","orcid":"https://orcid.org/0000-0002-0412-2748","observed_orcids":["https://orcid.org/0000-0002-0412-2748","https://orcid.org/0009-0005-2211-0272","https://orcid.org/0009-0007-2718-8436"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yanping Li","raw_affiliation_strings":["Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046838165","display_name":"Stephanie E. Chiuve","orcid":"https://orcid.org/0000-0002-3524-8917","observed_orcids":["https://orcid.org/0000-0002-3524-8917"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephanie E. Chiuve","raw_affiliation_strings":["Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts2Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts","Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts2Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067413533","display_name":"Meir J. Stampfer","orcid":"https://orcid.org/0000-0001-8865-935X","observed_orcids":["https://orcid.org/0000-0001-8865-935X"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meir J. Stampfer","raw_affiliation_strings":["Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts2Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts3Department of Epidemiology,","Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts2Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts3Department of Epidemiology,","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049411008","display_name":"JoAnn E. Manson","orcid":"https://orcid.org/0000-0002-9426-7595","observed_orcids":["https://orcid.org/0000-0002-9426-7595"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JoAnn E. Manson","raw_affiliation_strings":["Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts4Channing Division for Net","Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts4Channing Division for Net","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054114697","display_name":"Eric B. Rimm","orcid":"https://orcid.org/0000-0002-1402-7250","observed_orcids":["https://orcid.org/0000-0002-1402-7250"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric B. Rimm","raw_affiliation_strings":["Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts4Channing Division for Network Medicine, Brigham and Women\u2019s Hospital a","Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts4Channing Division for Network Medicine, Brigham and Women\u2019s Hospital a","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083991449","display_name":"Walter Churchill Willett","orcid":"https://orcid.org/0000-0003-1458-7597","observed_orcids":["https://orcid.org/0000-0003-1458-7597"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Walter C. Willett","raw_affiliation_strings":["Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts4Channing Division for Network Medicine, Brigham and Women\u2019s Hospital a","Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts4Channing Division for Network Medicine, Brigham and Women\u2019s Hospital a","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056459536","display_name":"Frank B. Hu","orcid":"https://orcid.org/0000-0002-8233-6274","observed_orcids":["https://orcid.org/0000-0002-8233-6274","https://orcid.org/0000-0002-8412-2261"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Frank B. Hu","raw_affiliation_strings":["Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts4Channing Division for Network Medicine, Brigham and Women\u2019s Hospital a","Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts4Channing Division for Network Medicine, Brigham and Women\u2019s Hospital a","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Channing Division for Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5056459536"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"],"apc_list":null,"apc_paid":null,"fwci":51.5042,"has_fulltext":true,"cited_by_count":443,"citation_normalized_percentile":{"value":0.9987897,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"176","issue":"8","first_page":"1134","last_page":"1134"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.7797999978065491,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.7797999978065491,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.218299999833107,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12314","display_name":"Nuts composition and effects","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dietary-fat","display_name":"dietary fat","score":0.8519999980926514},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.828000009059906},{"id":"https://openalex.org/keywords/cause-specific-mortality","display_name":"cause-specific mortality","score":0.9990000128746033},{"id":"https://openalex.org/keywords/saturated-fat","display_name":"saturated fat","score":0.968999981880188},{"id":"https://openalex.org/keywords/polyunsaturated-fatty-acids","display_name":"polyunsaturated fatty acids","score":0.9049999713897705},{"id":"https://openalex.org/keywords/monounsaturated-fatty-acids","display_name":"monounsaturated fatty acids","score":0.9990000128746033},{"id":"https://openalex.org/keywords/trans-fatty-acids","display_name":"trans fatty acids","score":0.8700000047683716},{"id":"https://openalex.org/keywords/fat-replacement","display_name":"fat replacement","score":0.6579999923706055},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.4650000035762787},{"id":"https://openalex.org/keywords/cancer-mortality","display_name":"cancer mortality","score":0.5659999847412109},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.46399998664855957},{"id":"https://openalex.org/keywords/nurses-health-study","display_name":"Nurses' Health Study","score":0.7879999876022339},{"id":"https://openalex.org/keywords/health-professionals-follow-up-study","display_name":"Health Professionals Follow-up Study","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dietary-assessment","display_name":"dietary assessment","score":0.4169999957084656},{"id":"https://openalex.org/keywords/men","display_name":"men","score":0.9950000047683716},{"id":"https://openalex.org/keywords/cohort-studies","display_name":"cohort studies","score":0.4490000009536743},{"id":"https://openalex.org/keywords/risk-factors-for-mortality","display_name":"mortality risk factors","score":0.49399998784065247}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.949664294719696},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.6231932640075684},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5674692392349243},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.47643882036209106},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.46393898129463196},{"id":"https://openalex.org/C3020261727","wikidata":"https://www.wikidata.org/wiki/Q970537","display_name":"Saturated fat","level":3,"score":0.4545830488204956},{"id":"https://openalex.org/C2777654188","wikidata":"https://www.wikidata.org/wiki/Q16947724","display_name":"National Death Index","level":4,"score":0.45305106043815613},{"id":"https://openalex.org/C29374701","wikidata":"https://www.wikidata.org/wiki/Q1931388","display_name":"Cause of death","level":3,"score":0.42460721731185913},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.41434818506240845},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.38420116901397705},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.3680979609489441},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35278230905532837},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.26153627038002014},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.08040478825569153},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D002423","descriptor_name":"Cause of Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004042","descriptor_name":"Dietary Fats, Unsaturated","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005518","descriptor_name":"Food Preferences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057140","descriptor_name":"Fast Foods","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D057141","descriptor_name":"Food, Preserved","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1001/jamainternmed.2016.2417","doi":"https://doi.org/10.1001/jamainternmed.2016.2417","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamainternmed.2016.2417","pdf_url":"https://jamanetwork.com/journals/jamainternalmedicine/articlepdf/2530902/ioi160037.pdf","source":{"id":"https://openalex.org/S65364685","display_name":"JAMA Internal Medicine","issn_l":"2168-6106","issn":["2168-6106","2168-6114"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Internal Medicine","raw_type":"journal-article"},{"id":"pmid:27379574","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27379574","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA internal medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5123772","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5123772","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"JAMA Intern Med","raw_type":"Text"},{"id":"pmh:oai:dash.harvard.edu:1/41263108","doi":null,"is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:41263108","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1001/jamainternmed.2016.2417","doi":"https://doi.org/10.1001/jamainternmed.2016.2417","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamainternmed.2016.2417","pdf_url":"https://jamanetwork.com/journals/jamainternalmedicine/articlepdf/2530902/ioi160037.pdf","source":{"id":"https://openalex.org/S65364685","display_name":"JAMA Internal Medicine","issn_l":"2168-6106","issn":["2168-6106","2168-6114"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Internal Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1255269144","display_name":"Dietary Patterns and Risk of Cardiovascular Disease","funder_award_id":"R01HL060712","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3581670783","display_name":"Dietary Etiologies of Heart Disease","funder_award_id":"R01HL035464","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3711098856","display_name":"Boston Nutrition Obesity Research Center","funder_award_id":"P30DK046200","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3965309116","display_name":"Dietary and Hormonal Determinants of Cancer in Women","funder_award_id":"P01CA087969","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7490235434","display_name":"Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health Study","funder_award_id":"UM1CA186107","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7908535992","display_name":"Cancer Epidemiology Cohort in Male Health Professionals","funder_award_id":"UM1CA167552","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000029955","display_name":null,"funder_award_id":"DK46200","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000122174","display_name":null,"funder_award_id":"CA-167552","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000190097","display_name":null,"funder_award_id":"CA 87969","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000911446","display_name":"RISK FACTORS FOR CVD IN WOMEN","funder_award_id":"R01HL034594","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000914019","display_name":"Risk Factors for Ischemic Stroke in Women","funder_award_id":"R01HL088521","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320316600","display_name":"California Walnut Commission","ror":"https://ror.org/03bg0ms48"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2470745271.pdf","grobid_xml":"https://content.openalex.org/works/W2470745271.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W1275357281","https://openalex.org/W1575865313","https://openalex.org/W1749005812","https://openalex.org/W1893861488","https://openalex.org/W1919063129","https://openalex.org/W1939555998","https://openalex.org/W1957265225","https://openalex.org/W1961127914","https://openalex.org/W1978718896","https://openalex.org/W2015008724","https://openalex.org/W2026316419","https://openalex.org/W2026876318","https://openalex.org/W2037420920","https://openalex.org/W2042346472","https://openalex.org/W2047224923","https://openalex.org/W2048457876","https://openalex.org/W2071703951","https://openalex.org/W2072883380","https://openalex.org/W2095768296","https://openalex.org/W2095864849","https://openalex.org/W2097178513","https://openalex.org/W2097226936","https://openalex.org/W2101513524","https://openalex.org/W2102323857","https://openalex.org/W2108791220","https://openalex.org/W2114995439","https://openalex.org/W2121413294","https://openalex.org/W2124522325","https://openalex.org/W2125288278","https://openalex.org/W2126271291","https://openalex.org/W2127287605","https://openalex.org/W2132710304","https://openalex.org/W2134471782","https://openalex.org/W2135902361","https://openalex.org/W2136604885","https://openalex.org/W2141656946","https://openalex.org/W2145941565","https://openalex.org/W2151255074","https://openalex.org/W2151604950","https://openalex.org/W2152692075","https://openalex.org/W2156924995","https://openalex.org/W2164707581","https://openalex.org/W2166000498","https://openalex.org/W2201393646","https://openalex.org/W2320460462","https://openalex.org/W2331989640","https://openalex.org/W2523217664","https://openalex.org/W2768747829","https://openalex.org/W3140330662","https://openalex.org/W3140984365","https://openalex.org/W4230403489","https://openalex.org/W4235003976","https://openalex.org/W4247636554","https://openalex.org/W4252616805","https://openalex.org/W7073873518","https://openalex.org/W7075730542"],"related_works":["https://openalex.org/W2555318194","https://openalex.org/W2910421614","https://openalex.org/W2982125443","https://openalex.org/W3043468756","https://openalex.org/W3014947543","https://openalex.org/W3192754427","https://openalex.org/W4407758055","https://openalex.org/W2034572238","https://openalex.org/W2955389705","https://openalex.org/W4402555253"],"abstract_inverted_index":{"IMPORTANCE:":[0],"Previous":[1],"studies":[2],"have":[3,373],"shown":[4],"distinct":[5],"associations":[6,30,375],"between":[7],"specific":[8,17,32,220],"dietary":[9,18,33,183,221,371,385],"fat":[10,19,102,185,390],"and":[11,20,24,37,69,93,96,108,129,159,179,249,275,292,378,391],"cardiovascular":[12,90],"disease.":[13],"However,":[14],"evidence":[15],"on":[16,116],"mortality":[21,39,117,195,215,284,304,333,351],"remains":[22],"limited":[23],"inconsistent.":[25],"OBJECTIVE:":[26],"To":[27],"examine":[28],"the":[29,58,74,124,130],"of":[31,89,123,127,168,213,219,265,285,308,323,370],"fats":[34,222,269,372],"with":[35,187,193,270,279,332,346,376,393],"total":[36,184,188,194,214,283,303,350,377],"cause-specific":[38,160,379],"in":[40,282],"2":[41,97,111],"large":[42],"ongoing":[43],"cohort":[44,51],"studies.":[45],"DESIGN,":[46],"SETTING,":[47],"AND":[48,156,366],"PARTICIPANTS:":[49],"This":[50],"study":[52],"investigated":[53],"83":[54],"349":[55],"women":[56],"from":[57,73,120,137,146,267,273],"Nurses'":[59],"Health":[60,75],"Study":[61,78],"(July":[62],"1,":[63,80],"1980,":[64],"to":[65,82,112,150,335,387],"June":[66],"30,":[67],"2012)":[68,85],"42":[70],"884":[71],"men":[72],"Professionals":[76],"Follow-up":[77],"(February":[79],"1986,":[81],"January":[83],"31,":[84],"who":[86],"were":[87,144,173,223],"free":[88],"disease,":[91],"cancer,":[92],"types":[94,369],"1":[95],"diabetes":[98],"at":[99,106],"baseline.":[100],"Dietary":[101],"intake":[103,311,343],"was":[104,118,190,277,312,329,344],"assessed":[105],"baseline":[107],"updated":[109],"every":[110],"4":[113],"years.":[114],"Information":[115],"obtained":[119],"systematic":[121],"searches":[122],"vital":[125],"records":[126],"states":[128],"National":[131],"Death":[132],"Index,":[133],"supplemented":[134],"by":[135],"reports":[136],"family":[138],"members":[139],"or":[140],"postal":[141],"authorities.":[142],"Data":[143],"analyzed":[145],"September":[147],"18,":[148],"2014,":[149],"March":[151],"27,":[152],"2016.":[153],"MAIN":[154],"OUTCOMES":[155],"MEASURES:":[157],"Total":[158],"mortality.":[161,380],"RESULTS:":[162],"During":[163],"3":[164],"439":[165],"954":[166],"person-years":[167],"follow-up,":[169],"33":[170],"304":[171],"deaths":[172],"documented.":[174],"After":[175],"adjustment":[176],"for":[177,209,228,235,244,254,259,261,302,320,363],"known":[178],"suspected":[180],"risk":[181],"factors,":[182],"compared":[186],"carbohydrates":[189],"inversely":[191,330],"associated":[192,278,331,345],"(hazard":[196],"ratio":[197],"[HR]":[198],"comparing":[199,216,305,353],"extreme":[200,217,306,354],"quintiles,":[201,355],"0.84;":[202],"95%":[203,289,296,357],"CI,":[204,226,233,242,252,290,297,315,358],"0.81-0.88;":[205],"P":[206,317,360],"<":[207,257,318],".001":[208,258,319],"trend).":[210,321,364],"The":[211,300],"HRs":[212],"quintiles":[218,307],"1.08":[224],"(95%":[225,232,241,251,314],"1.03-1.14)":[227],"saturated":[229,268,389],"fat,":[230],"0.81":[231],"0.78-0.84)":[234],"polyunsaturated":[236],"fatty":[237,246],"acid":[238,247],"(PUFA),":[239],"0.89":[240],"0.84-0.94)":[243],"monounsaturated":[245],"(MUFA),":[248],"1.13":[250],"1.07-1.18)":[253],"trans-fat":[255,392],"(P":[256],"trend":[260],"all).":[262],"Replacing":[263],"5%":[264],"energy":[266,272],"equivalent":[271],"PUFA":[274,310,342],"MUFA":[276],"estimated":[280],"reductions":[281],"27%":[286],"(HR,":[287,294],"0.73;":[288],"0.70-0.77)":[291],"13%":[293],"0.87;":[295],"0.82-0.93),":[298],"respectively.":[299],"HR":[301],"\u03c9-6":[309,324],"0.85":[313],"0.81-0.89;":[316],"Intake":[322],"PUFA,":[325],"especially":[326],"linoleic":[327],"acid,":[328],"owing":[334],"most":[336],"major":[337],"causes,":[338],"whereas":[339],"marine":[340],"\u03c9-3":[341],"a":[347],"modestly":[348],"lower":[349],"(HR":[352],"0.96;":[356],"0.93-1.00;":[359],"=":[361],".002":[362],"CONCLUSIONS":[365],"RELEVANCE:":[367],"Different":[368],"divergent":[374],"These":[381],"findings":[382],"support":[383],"current":[384],"recommendations":[386],"replace":[388],"unsaturated":[394],"fats.":[395]},"counts_by_year":[{"year":2026,"cited_by_count":21},{"year":2025,"cited_by_count":31},{"year":2024,"cited_by_count":32},{"year":2023,"cited_by_count":34},{"year":2022,"cited_by_count":39},{"year":2021,"cited_by_count":54},{"year":2020,"cited_by_count":48},{"year":2019,"cited_by_count":53},{"year":2018,"cited_by_count":69},{"year":2017,"cited_by_count":38},{"year":2016,"cited_by_count":21}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-07-22T00:00:00"}