{"id":"https://openalex.org/W2470697378","doi":"https://doi.org/10.15407/fz56.04.047","title":"Changes of vascular reactivity and reactive oxygen species in conditions of varying duration of permanent stay in the alienation zone in mice","display_name":"Changes of vascular reactivity and reactive oxygen species in conditions of varying duration of permanent stay in the alienation zone in mice","publication_year":2010,"publication_date":"2010-07-15","ids":{"openalex":"https://openalex.org/W2470697378","doi":"https://doi.org/10.15407/fz56.04.047","mag":"2470697378","pmid":"https://pubmed.ncbi.nlm.nih.gov/20968037"},"language":"uk","primary_location":{"id":"doi:10.15407/fz56.04.047","doi":"https://doi.org/10.15407/fz56.04.047","is_oa":true,"landing_page_url":"https://doi.org/10.15407/fz56.04.047","pdf_url":"https://fz.kiev.ua/journals/2010_V.56/Fiziologichnyi%20Zhurnal%2056(4)_2010/Fiziologichnyi Zhurnal 56(4)__2010_47-58.pdf","source":{"id":"https://openalex.org/S4210192914","display_name":"F\u00ecz\u00ecolog\u00ec\u010dnij \u017eurnal","issn_l":"0015-3311","issn":["0015-3311","0201-8489","2522-9028","2522-9036"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fiziolohichny\u012d zhurnal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://fz.kiev.ua/journals/2010_V.56/Fiziologichnyi%20Zhurnal%2056(4)_2010/Fiziologichnyi Zhurnal 56(4)__2010_47-58.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110798588","display_name":"M M Tkachenko","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MM Tkachenko","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113751828","display_name":"A V Kotsiuruba","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"AV Kotsiuruba","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074960175","display_name":"O V Baziliuk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"OV Baziliuk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021709492","display_name":"IV Horot'","orcid":"https://orcid.org/0000-0003-0467-7812","observed_orcids":["https://orcid.org/0000-0003-0467-7812"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"IV Horot'","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5077669285","display_name":"V F Sahach","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"VF Sahach","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.39418952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"56","issue":"4","first_page":"47","last_page":"58"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.013399999588727951,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-reactivity","display_name":"vascular reactivity","score":0.9350000023841858},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7210000157356262},{"id":"https://openalex.org/keywords/endothelium-dependent-relaxation","display_name":"endothelium-dependent relaxation","score":0.796999990940094},{"id":"https://openalex.org/keywords/thoracic-aorta","display_name":"thoracic aorta","score":0.8140000104904175},{"id":"https://openalex.org/keywords/acetylcholine","display_name":"acetylcholine","score":0.8320000171661377},{"id":"https://openalex.org/keywords/arginine-metabolism","display_name":"arginine metabolism","score":0.8149999976158142},{"id":"https://openalex.org/keywords/low-dose-radiation","display_name":"low-dose radiation","score":0.8230000138282776},{"id":"https://openalex.org/keywords/superoxide-radicals","display_name":"superoxide","score":0.8149999976158142},{"id":"https://openalex.org/keywords/hydroxyl-radicals","display_name":"hydroxyl radicals","score":0.9440000057220459},{"id":"https://openalex.org/keywords/mitochondrial-oxidative-stress","display_name":"mitochondrial oxidative stress","score":0.6200000047683716},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.5}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6482411026954651},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.6309374570846558},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.6184985041618347},{"id":"https://openalex.org/C2776864027","wikidata":"https://www.wikidata.org/wiki/Q615993","display_name":"Thoracic aorta","level":3,"score":0.6146330237388611},{"id":"https://openalex.org/C2775910092","wikidata":"https://www.wikidata.org/wiki/Q180623","display_name":"Acetylcholine","level":2,"score":0.6026333570480347},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.5740074515342712},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.5615606904029846},{"id":"https://openalex.org/C139066938","wikidata":"https://www.wikidata.org/wiki/Q185056","display_name":"Radical","level":2,"score":0.5478770136833191},{"id":"https://openalex.org/C164007495","wikidata":"https://www.wikidata.org/wiki/Q24721374","display_name":"Arginase","level":4,"score":0.5227584838867188},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.5059825778007507},{"id":"https://openalex.org/C2780795997","wikidata":"https://www.wikidata.org/wiki/Q413283","display_name":"Superoxide","level":3,"score":0.5045980215072632},{"id":"https://openalex.org/C2776910235","wikidata":"https://www.wikidata.org/wiki/Q18574","display_name":"Reactivity (psychology)","level":3,"score":0.4738624095916748},{"id":"https://openalex.org/C2776029896","wikidata":"https://www.wikidata.org/wiki/Q3935810","display_name":"Relaxation (psychology)","level":2,"score":0.4306182265281677},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3807483911514282},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3579862713813782},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.3495509624481201},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3347311019897461},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15011847019195557},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12785929441452026},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12702015042304993},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D004307","descriptor_name":"Dose-Response Relationship, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009131","descriptor_name":"Muscle, Smooth, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009131","descriptor_name":"Muscle, Smooth, Vascular","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014455","descriptor_name":"Ukraine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014664","descriptor_name":"Vasodilation","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D047852","descriptor_name":"Chernobyl Nuclear Accident","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.15407/fz56.04.047","doi":"https://doi.org/10.15407/fz56.04.047","is_oa":true,"landing_page_url":"https://doi.org/10.15407/fz56.04.047","pdf_url":"https://fz.kiev.ua/journals/2010_V.56/Fiziologichnyi%20Zhurnal%2056(4)_2010/Fiziologichnyi Zhurnal 56(4)__2010_47-58.pdf","source":{"id":"https://openalex.org/S4210192914","display_name":"F\u00ecz\u00ecolog\u00ec\u010dnij \u017eurnal","issn_l":"0015-3311","issn":["0015-3311","0201-8489","2522-9028","2522-9036"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fiziolohichny\u012d zhurnal","raw_type":"journal-article"},{"id":"pmid:20968037","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20968037","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)","raw_type":"English Abstract"}],"best_oa_location":{"id":"doi:10.15407/fz56.04.047","doi":"https://doi.org/10.15407/fz56.04.047","is_oa":true,"landing_page_url":"https://doi.org/10.15407/fz56.04.047","pdf_url":"https://fz.kiev.ua/journals/2010_V.56/Fiziologichnyi%20Zhurnal%2056(4)_2010/Fiziologichnyi Zhurnal 56(4)__2010_47-58.pdf","source":{"id":"https://openalex.org/S4210192914","display_name":"F\u00ecz\u00ecolog\u00ec\u010dnij \u017eurnal","issn_l":"0015-3311","issn":["0015-3311","0201-8489","2522-9028","2522-9036"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fiziolohichny\u012d zhurnal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2470697378.pdf","grobid_xml":"https://content.openalex.org/works/W2470697378.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1973133531","https://openalex.org/W1976851726","https://openalex.org/W2044062716","https://openalex.org/W2047440399","https://openalex.org/W2049413621","https://openalex.org/W2058137293","https://openalex.org/W2060023756","https://openalex.org/W2099576328","https://openalex.org/W2157553830","https://openalex.org/W2159827287"],"related_works":["https://openalex.org/W1995149139","https://openalex.org/W2065092575","https://openalex.org/W2419009117","https://openalex.org/W2995311045","https://openalex.org/W3930824","https://openalex.org/W2157530334","https://openalex.org/W2077980705","https://openalex.org/W2049241488","https://openalex.org/W2168817183","https://openalex.org/W1988516416"],"abstract_inverted_index":{"Peculiarities":[0],"of":[1,11,14,19,29,34,60,64,66,69,76,82,86,93,95,98,100,108,113,116,119,126,128,131,146,149,152,157,164,166,173,175],"changes":[2],"in":[3,8,25,49,111,142],"the":[4,9,26,35,50,70,101],"vascular":[5],"reactivity":[6],"and":[7,16,31,40,46,79,135],"content":[10],"reactive":[12,129],"forms":[13,130],"oxygen":[15],"stable":[17],"metabolites":[18],"nitric":[20],"oxide":[21],"(NO)":[22],"were":[23,44],"studied":[24],"aorta":[27,103],"preparations":[28],"C57BL/6":[30],"BALB/c":[32],"mice":[33],"two":[36],"age":[37],"groups":[38],"(6":[39],"18":[41],"mo.),":[42],"which":[43,138],"born":[45],"permanently":[47],"kept":[48],"Chernobyl":[51],"alienation":[52],"zone.":[53],"The":[54],"results":[55],"obtained":[56],"showed":[57],"a":[58,90,154,170],"disturbance":[59],"acetylcholine-induced":[61],"endothelium-dependent":[62,96,176],"reactions":[63,97],"relaxation":[65,99],"smooth":[67,104],"muscles":[68],"thoracic":[71,102],"aorta.":[72],"A":[73,106],"lower":[74,80],"level":[75,81,156,172],"NO":[77,109],"synthesis":[78,110],"oxidative":[83],"arginase":[84],"metabolism":[85],"arginine":[87],"corresponded":[88,168],"to":[89,169],"higher":[91,171],"degree":[92],"damage":[94,174],"muscles.":[105],"decrease":[107],"conditions":[112,145],"permanent":[114,147],"effects":[115,148],"low":[117,150],"doses":[118,151],"radiation":[120,153],"was":[121],"conditioned":[122],"by":[123],"an":[124],"increase":[125],"generation":[127,165],"oxygen,":[132],"namely,":[133],"superoxide":[134],"hydroxyl":[136],"radicals,":[137],"might":[139],"be":[140],"formed":[141],"mitochondria.":[143],"In":[144],"lesser":[155,162],"protein":[158],"nitrosothilation,":[159],"same":[160],"as":[161],"one":[163],"OH-radical,":[167],"reactions.":[177]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-07-22T00:00:00"}