{"id":"https://openalex.org/W2468689986","doi":"https://doi.org/10.1590/0104-1428.2323","title":"Influence of PLGA and PLGA-PEG on the dissolution profile of oxaliplatin","display_name":"Influence of PLGA and PLGA-PEG on the dissolution profile of oxaliplatin","publication_year":2016,"publication_date":"2016-06-04","ids":{"openalex":"https://openalex.org/W2468689986","doi":"https://doi.org/10.1590/0104-1428.2323","mag":"2468689986"},"language":"nl","primary_location":{"id":"doi:10.1590/0104-1428.2323","doi":"https://doi.org/10.1590/0104-1428.2323","is_oa":true,"landing_page_url":"https://doi.org/10.1590/0104-1428.2323","pdf_url":"http://www.scielo.br/pdf/po/v26n2/0104-1428-po-0104-14282323.pdf","source":{"id":"https://openalex.org/S27902081","display_name":"Pol\u00edmeros","issn_l":"0104-1428","issn":["0104-1428","1678-5169","1984-7386"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312096","host_organization_name":"Associa\u00e7\u00e3o Brasileira de Pol\u00edmeros","host_organization_lineage":["https://openalex.org/P4310312096"],"host_organization_lineage_names":["Associa\u00e7\u00e3o Brasileira de Pol\u00edmeros"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pol\u00edmeros","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.scielo.br/pdf/po/v26n2/0104-1428-po-0104-14282323.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030660192","display_name":"Emiliane Daher Pereira","orcid":"https://orcid.org/0000-0002-4857-9512","observed_orcids":["https://orcid.org/0000-0002-4857-9512"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Emiliane Daher Pereira","raw_affiliation_strings":["Universidade Federal do Rio de Janeiro,  Brazil","Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio de Janeiro,  Brazil","institution_ids":["https://openalex.org/I122140584"]},{"raw_affiliation_string":"Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048135937","display_name":"Renata Cerruti da Costa","orcid":"https://orcid.org/0000-0001-7610-8745","observed_orcids":["https://orcid.org/0000-0001-7610-8745"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Renata Cerruti","raw_affiliation_strings":["Universidade Federal do Rio de Janeiro,  Brazil","Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio de Janeiro,  Brazil","institution_ids":["https://openalex.org/I122140584"]},{"raw_affiliation_string":"Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111540114","display_name":"Edson Rodrigo Fernandes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Edson Fernandes","raw_affiliation_strings":["Universidade Federal do Rio de Janeiro,  Brazil","Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio de Janeiro,  Brazil","institution_ids":["https://openalex.org/I122140584"]},{"raw_affiliation_string":"Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079783850","display_name":"Luis Pe\u00f1a","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2656126","display_name":"University of Havana","ror":"https://ror.org/04204gr61","country_code":"CU","type":"education","lineage":["https://openalex.org/I2656126"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"Luis Pe\u00f1a","raw_affiliation_strings":["Universidad de La Habana,  Cuba","Centro de Biomateriales, Universidad de La Habana, Havana, Cuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad de La Habana,  Cuba","institution_ids":["https://openalex.org/I2656126"]},{"raw_affiliation_string":"Centro de Biomateriales, Universidad de La Habana, Havana, Cuba","institution_ids":["https://openalex.org/I2656126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043192345","display_name":"Vivian M. Saez","orcid":"https://orcid.org/0000-0002-5427-1928","observed_orcids":["https://orcid.org/0000-0002-5427-1928"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]},{"id":"https://openalex.org/I2656126","display_name":"University of Havana","ror":"https://ror.org/04204gr61","country_code":"CU","type":"education","lineage":["https://openalex.org/I2656126"]}],"countries":["BR","CU"],"is_corresponding":false,"raw_author_name":"Vivian Saez","raw_affiliation_strings":["Universidade Federal do Rio de Janeiro,  Brazil; Universidad de La Habana,  Cuba","Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, BrazilCentro de Biomateriales, Universidad de La Habana, Havana, Cuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio de Janeiro,  Brazil; Universidad de La Habana,  Cuba","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I2656126"]},{"raw_affiliation_string":"Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, BrazilCentro de Biomateriales, Universidad de La Habana, Havana, Cuba","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I2656126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101767121","display_name":"Jos\u00e9 Carlos Pinto","orcid":"https://orcid.org/0000-0003-2631-1811","observed_orcids":["https://orcid.org/0000-0003-2631-1811"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Carlos Pinto","raw_affiliation_strings":["Universidade Federal do Rio de Janeiro,  Brazil","Programa de Engenharia Quimica, Instituto Alberto Luiz Coimbra de Pos-graduacao e Pesquisa de Engenharia - COPPE, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio de Janeiro,  Brazil","institution_ids":["https://openalex.org/I122140584"]},{"raw_affiliation_string":"Programa de Engenharia Quimica, Instituto Alberto Luiz Coimbra de Pos-graduacao e Pesquisa de Engenharia - COPPE, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078625990","display_name":"Jos\u00e9 Ram\u00f3n","orcid":"https://orcid.org/0000-0002-9174-582X","observed_orcids":["https://orcid.org/0000-0002-9174-582X"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]},{"id":"https://openalex.org/I2656126","display_name":"University of Havana","ror":"https://ror.org/04204gr61","country_code":"CU","type":"education","lineage":["https://openalex.org/I2656126"]}],"countries":["BR","CU"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Angel Ram\u00f3n","raw_affiliation_strings":["Universidade Federal do Rio de Janeiro,  Brazil; Universidad de La Habana,  Cuba; Universidade Federal do Rio de Janeiro,  Brazil","Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, BrazilCentro de Biomateriales, Universidad de La Habana, Havana, CubaPrograma de Engenharia Quimica, Instituto Alberto Luiz Coimbra de Pos-graduacao e Pesquisa de Engenharia - COPPE, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio de Janeiro,  Brazil; Universidad de La Habana,  Cuba; Universidade Federal do Rio de Janeiro,  Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I2656126"]},{"raw_affiliation_string":"Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, BrazilCentro de Biomateriales, Universidad de La Habana, Havana, CubaPrograma de Engenharia Quimica, Instituto Alberto Luiz Coimbra de Pos-graduacao e Pesquisa de Engenharia - COPPE, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I2656126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103817384","display_name":"Geiza E. Oliveira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]},{"id":"https://openalex.org/I51235708","display_name":"Universidade Federal do Esp\u00edrito Santo","ror":"https://ror.org/05sxf4h28","country_code":"BR","type":"education","lineage":["https://openalex.org/I51235708"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Geiza Esperandio Oliveira","raw_affiliation_strings":["Universidade Federal do Rio de Janeiro,  Brazil; Universidade Federal do Esp\u00edrito Santo,  Brazil","Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, BrazilDepartamento de Quimica, Universidade Federal do Espirito Santo - UFES, Vitoria, ES, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio de Janeiro,  Brazil; Universidade Federal do Esp\u00edrito Santo,  Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I51235708"]},{"raw_affiliation_string":"Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, BrazilDepartamento de Quimica, Universidade Federal do Espirito Santo - UFES, Vitoria, ES, Brazil","institution_ids":["https://openalex.org/I122140584","https://openalex.org/I51235708"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067000786","display_name":"Fernando Gomes de Souza","orcid":"https://orcid.org/0000-0002-8332-4953","observed_orcids":["https://orcid.org/0000-0002-8332-4953"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fernando Gomes de Souza J\u00fanior","raw_affiliation_strings":["Universidade Federal do Rio de Janeiro,  Brazil; Universidade Federal do Rio de Janeiro,  Brazil","Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, BrazilPrograma de Engenharia Civil, Instituto Alberto Luiz Coimbra de Pos-graduacao e Pesquisa de Engenharia - COPPE, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio de Janeiro,  Brazil; Universidade Federal do Rio de Janeiro,  Brazil","institution_ids":["https://openalex.org/I122140584"]},{"raw_affiliation_string":"Laboratorio de Biopolimeros e Sensores, Instituto de Macromoleculas, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, BrazilPrograma de Engenharia Civil, Instituto Alberto Luiz Coimbra de Pos-graduacao e Pesquisa de Engenharia - COPPE, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":800,"currency":"BRL","value_usd":152},"apc_paid":{"value":800,"currency":"BRL","value_usd":152},"fwci":2.0916,"has_fulltext":true,"cited_by_count":62,"citation_normalized_percentile":{"value":0.83494953,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"26","issue":"2","first_page":"137","last_page":"143"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.8633000254631042,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.8633000254631042,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.054499998688697815,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.026100000366568565,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oxaliplatin","display_name":"oxaliplatin","score":1.0},{"id":"https://openalex.org/keywords/plga","display_name":"PLGA","score":0.9049999713897705},{"id":"https://openalex.org/keywords/polyethylene-glycol","display_name":"polyethylene glycol","score":0.9819999933242798},{"id":"https://openalex.org/keywords/drug-release-profile","display_name":"drug release profile","score":0.6330000162124634},{"id":"https://openalex.org/keywords/dissolution","display_name":"dissolution","score":0.5350000262260437},{"id":"https://openalex.org/keywords/drug-polymer-interactions","display_name":"drug-polymer interactions","score":0.9300000071525574},{"id":"https://openalex.org/keywords/controlled-drug-release","display_name":"controlled drug release","score":0.6200000047683716},{"id":"https://openalex.org/keywords/anticancer-drug-delivery","display_name":"anticancer drug delivery","score":0.640999972820282},{"id":"https://openalex.org/keywords/biocompatibility","display_name":"biocompatibility","score":0.5329999923706055}],"concepts":[{"id":"https://openalex.org/C2780165375","wikidata":"https://www.wikidata.org/wiki/Q2102907","display_name":"PLGA","level":3,"score":0.7665202021598816},{"id":"https://openalex.org/C54400483","wikidata":"https://www.wikidata.org/wiki/Q1793202","display_name":"PEG ratio","level":2,"score":0.6326898336410522},{"id":"https://openalex.org/C2780962732","wikidata":"https://www.wikidata.org/wiki/Q422327","display_name":"Oxaliplatin","level":4,"score":0.5596557855606079},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.5554997324943542},{"id":"https://openalex.org/C2776964284","wikidata":"https://www.wikidata.org/wiki/Q410083","display_name":"Polyethylene glycol","level":2,"score":0.5190061330795288},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4826372265815735},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45579206943511963},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.43700069189071655},{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.42547234892845154},{"id":"https://openalex.org/C160892712","wikidata":"https://www.wikidata.org/wiki/Q901559","display_name":"Fourier transform infrared spectroscopy","level":2,"score":0.42028194665908813},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3997178375720978},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.26732656359672546},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.21453487873077393},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.09241896867752075},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.05533057451248169},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.04882723093032837},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1590/0104-1428.2323","doi":"https://doi.org/10.1590/0104-1428.2323","is_oa":true,"landing_page_url":"https://doi.org/10.1590/0104-1428.2323","pdf_url":"http://www.scielo.br/pdf/po/v26n2/0104-1428-po-0104-14282323.pdf","source":{"id":"https://openalex.org/S27902081","display_name":"Pol\u00edmeros","issn_l":"0104-1428","issn":["0104-1428","1678-5169","1984-7386"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312096","host_organization_name":"Associa\u00e7\u00e3o Brasileira de Pol\u00edmeros","host_organization_lineage":["https://openalex.org/P4310312096"],"host_organization_lineage_names":["Associa\u00e7\u00e3o Brasileira de Pol\u00edmeros"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pol\u00edmeros","raw_type":"journal-article"},{"id":"pmh:oai:scielo:S0104-14282016000200137","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282016000200137","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pol\u00edmeros v.26 n.2 2016","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2739998","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282016000200137","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pol\u00edmeros v.26 n.2 2016","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:ab62bfb28c584e209be13b6a3762d7c2","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ab62bfb28c584e209be13b6a3762d7c2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pol\u00edmeros, Vol 26, Iss 2, Pp 137-143","raw_type":"article"},{"id":"pmh:oai:redalyc.org:47046375006","doi":null,"is_oa":false,"landing_page_url":"https://www.redalyc.org/articulo.oa?id=47046375006","pdf_url":null,"source":{"id":"https://openalex.org/S4377196100","display_name":"Redalyc (Universidad Aut\u00f3noma del Estado de M\u00e9xico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I179647637","host_organization_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","host_organization_lineage":["https://openalex.org/I179647637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pol\u00edmeros: Ci\u00eancia e Tecnologia (Brasil) Num.2 Vol.26","raw_type":"art\u00edculo cient\u00edfico"}],"best_oa_location":{"id":"doi:10.1590/0104-1428.2323","doi":"https://doi.org/10.1590/0104-1428.2323","is_oa":true,"landing_page_url":"https://doi.org/10.1590/0104-1428.2323","pdf_url":"http://www.scielo.br/pdf/po/v26n2/0104-1428-po-0104-14282323.pdf","source":{"id":"https://openalex.org/S27902081","display_name":"Pol\u00edmeros","issn_l":"0104-1428","issn":["0104-1428","1678-5169","1984-7386"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312096","host_organization_name":"Associa\u00e7\u00e3o Brasileira de Pol\u00edmeros","host_organization_lineage":["https://openalex.org/P4310312096"],"host_organization_lineage_names":["Associa\u00e7\u00e3o Brasileira de Pol\u00edmeros"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pol\u00edmeros","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2468689986.pdf","grobid_xml":"https://content.openalex.org/works/W2468689986.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1966631624","https://openalex.org/W1978256874","https://openalex.org/W1978747630","https://openalex.org/W1982095120","https://openalex.org/W1983181930","https://openalex.org/W1988866063","https://openalex.org/W2001903101","https://openalex.org/W2008342394","https://openalex.org/W2009841111","https://openalex.org/W2015393080","https://openalex.org/W2022293366","https://openalex.org/W2023671240","https://openalex.org/W2027743405","https://openalex.org/W2029255146","https://openalex.org/W2029742977","https://openalex.org/W2030128478","https://openalex.org/W2031431719","https://openalex.org/W2032896586","https://openalex.org/W2035458207","https://openalex.org/W2037901026","https://openalex.org/W2039112796","https://openalex.org/W2039155953","https://openalex.org/W2046574646","https://openalex.org/W2050656614","https://openalex.org/W2055089903","https://openalex.org/W2057876241","https://openalex.org/W2059674127","https://openalex.org/W2059746305","https://openalex.org/W2069000687","https://openalex.org/W2078826690","https://openalex.org/W2079407952","https://openalex.org/W2082376230","https://openalex.org/W2087838893","https://openalex.org/W2092970481","https://openalex.org/W2093867661","https://openalex.org/W2095495590","https://openalex.org/W2095559227","https://openalex.org/W2133641362","https://openalex.org/W2139506346","https://openalex.org/W2148301564","https://openalex.org/W2153409108","https://openalex.org/W2166820203","https://openalex.org/W2171416093","https://openalex.org/W2320580673","https://openalex.org/W2322860057","https://openalex.org/W2332891049","https://openalex.org/W2808075006","https://openalex.org/W4229909943"],"related_works":["https://openalex.org/W2090319445","https://openalex.org/W2789649640","https://openalex.org/W4408261281","https://openalex.org/W2001881925","https://openalex.org/W2189069574","https://openalex.org/W2088480951","https://openalex.org/W2127586717","https://openalex.org/W2593676592","https://openalex.org/W2050207992","https://openalex.org/W2348972019"],"abstract_inverted_index":{"Oxaliplatin":[0,54,136],"was":[1,55,137,152],"inserted":[2],"into":[3],"polymeric":[4],"matrices":[5,59,103,113],"aiming":[6],"to":[7,20,22],"study":[8],"the":[9,23,58,61,85,90,93,98,105,109,122,159,165,168,175,184,188,191,196,199],"interaction":[10,99,157],"of":[11,40,84,92,108,155,177,187,198],"this":[12],"drug":[13,101,131,179,189],"with":[14,158],"these":[15,112],"polymers":[16,26,86],"and":[17,36,79,102,104,128,142,170,194],"its":[18],"capability":[19],"diffuse":[21],"environment.":[24],"Tested":[25],"were:":[27],"(1)":[28],"polyethylene":[29],"glycol":[30],"(PEG),":[31],"(2)":[32],"poly(lactic-co-glycolic":[33],"acid)":[34],"(PLGA),":[35],"(3)":[37],"a":[38,148,178],"copolymer":[39],"them":[41],"(PLGA-PEG).":[42],"The":[43],"latter":[44],"two":[45],"were":[46,87,114],"synthesized":[47],"by":[48,60,66,147],"us":[49],"using":[50],"polycondensation":[51],"in":[52,57,144],"bulk.":[53],"included":[56],"melt":[62],"mixing":[63],"process":[64],"followed":[65],"casting.":[67],"Fourier":[68],"tran":[69],"sform":[70],"infrared":[71],"spectroscopy":[72],"(FTIR),":[73],"proton":[74],"nuclear":[75],"magnetic":[76],"resonance":[77],"(1H-NMR)":[78],"X-ray":[80],"diffraction":[81],"(DRX)":[82],"studies":[83],"performed":[88],"proving":[89],"obtaining":[91,176],"desired":[94],"materials.":[95],"In":[96,125,162],"addition,":[97,163],"between":[100],"release":[106,132,180],"profile":[107],"oxaliplatin":[110,123,156],"from":[111,140],"analyzed.":[115],"Among":[116],"them,":[117],"PEG":[118,166],"did":[119],"not":[120],"control":[121],"release.":[124],"turn,":[126],"PLGA":[127,141],"PLGA-PEG":[129,143],"present":[130],"profiles":[133],"quite":[134],"similar.":[135],"completely":[138],"released":[139],"5":[145],"hours,":[146],"relaxation":[149],"mechanism.":[150],"There":[151],"no":[153],"evidence":[154],"different":[160],"polymers.":[161],"as":[164],"improves":[167],"biocompatibility":[169],"biomasking,":[171],"obtained":[172],"results":[173],"prove":[174],"system,":[181],"which":[182],"allowed":[183],"total":[185],"use":[186],"improving":[190],"cancer":[192],"treatment":[193],"even":[195],"welfare":[197],"patients.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-07-22T00:00:00"}