{"id":"https://openalex.org/W2468638892","doi":null,"title":"[Enzymologic study of the structural organization of the matrix or rat liver peroxisomes].","display_name":"[Enzymologic study of the structural organization of the matrix or rat liver peroxisomes].","publication_year":1978,"publication_date":"1978-06-01","ids":{"openalex":"https://openalex.org/W2468638892","mag":"2468638892","pmid":"https://pubmed.ncbi.nlm.nih.gov/29368"},"language":"ru","primary_location":{"id":"pmid:29368","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tsitologiia","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075233649","display_name":"Antonenkov Vd","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V D Antonenkov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5073128232","display_name":"A M Gerasimov","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A M Gerasimov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.44360902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":"6","first_page":"676","last_page":"81"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.45899999141693115,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.45899999141693115,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.08950000256299973,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.08869999647140503,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/liver-peroxisomes","display_name":"liver peroxisomes","score":0.8870000243186951},{"id":"https://openalex.org/keywords/enzyme-solubilization","display_name":"enzyme solubilization","score":0.8140000104904175},{"id":"https://openalex.org/keywords/ionic-strength","display_name":"ionic strength","score":0.703000009059906},{"id":"https://openalex.org/keywords/ph","display_name":"pH","score":0.843999981880188},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.8339999914169312},{"id":"https://openalex.org/keywords/isocitrate-dehydrogenase","display_name":"isocitrate dehydrogenase","score":0.9760000109672546},{"id":"https://openalex.org/keywords/glycerophosphate-dehydrogenase","display_name":"glycerophosphate dehydrogenase","score":0.9940000176429749},{"id":"https://openalex.org/keywords/lactate-dehydrogenase","display_name":"lactate dehydrogenase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/urate-oxidase","display_name":"uricase","score":0.996999979019165},{"id":"https://openalex.org/keywords/nadh-cytochrome-c-reductase","display_name":"NADH-cytochrome c reductase","score":0.9520000219345093},{"id":"https://openalex.org/keywords/d-amino-acid-oxidase","display_name":"D-amino acid oxidase","score":0.9940000176429749},{"id":"https://openalex.org/keywords/peroxisomal-membrane","display_name":"peroxisomal membrane","score":0.7450000047683716},{"id":"https://openalex.org/keywords/triton-x-100","display_name":"Triton X-100","score":0.7749999761581421},{"id":"https://openalex.org/keywords/enzyme-association","display_name":"enzyme association","score":0.4749999940395355},{"id":"https://openalex.org/keywords/rat-liver","display_name":"rat liver","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C127078168","wikidata":"https://www.wikidata.org/wiki/Q138639","display_name":"Peroxisome","level":3,"score":0.8991041779518127},{"id":"https://openalex.org/C2776943133","wikidata":"https://www.wikidata.org/wiki/Q18057009","display_name":"Urate oxidase","level":3,"score":0.8267456889152527},{"id":"https://openalex.org/C38485361","wikidata":"https://www.wikidata.org/wiki/Q576379","display_name":"Oxidase test","level":3,"score":0.684772253036499},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6813680529594421},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6023396253585815},{"id":"https://openalex.org/C123249941","wikidata":"https://www.wikidata.org/wiki/Q306116","display_name":"Cytochrome c oxidase","level":3,"score":0.5787118673324585},{"id":"https://openalex.org/C2776317432","wikidata":"https://www.wikidata.org/wiki/Q412547","display_name":"Dehydrogenase","level":3,"score":0.5101830959320068},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5057306289672852},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000594","descriptor_name":"Amino Acid Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002374","descriptor_name":"Catalase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005993","descriptor_name":"Glycerolphosphate Dehydrogenase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007521","descriptor_name":"Isocitrate Dehydrogenase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007770","descriptor_name":"L-Lactate Dehydrogenase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008830","descriptor_name":"Microbodies","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D008830","descriptor_name":"Microbodies","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009251","descriptor_name":"NADPH-Ferrihemoprotein Reductase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009940","descriptor_name":"Organoids","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014503","descriptor_name":"Urate Oxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:29368","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tsitologiia","raw_type":"Comparative Study"},{"id":"mag:2468638892","doi":null,"is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pubmed/29368","pdf_url":null,"source":{"id":"https://openalex.org/S2753356998","display_name":"Tsitologiya","issn_l":"0041-3771","issn":["0041-3771"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Tsitologiya","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2001274658","https://openalex.org/W2080667215","https://openalex.org/W2049509016","https://openalex.org/W1966079498","https://openalex.org/W7095284012","https://openalex.org/W2126925971","https://openalex.org/W2101812574","https://openalex.org/W2094618104","https://openalex.org/W2124608049","https://openalex.org/W2085062077"],"abstract_inverted_index":{"The":[0],"effect":[1],"of":[2,10,13,16,67],"ionic":[3],"strength":[4],"and":[5,32,44,57,84],"pH":[6],"on":[7],"the":[8,14,39,65,74,101],"release":[9],"some":[11],"enzymes":[12],"matrix":[15],"peroxisomes":[17],"in":[18,100],"rat's":[19],"liver":[20],"was":[21],"studied.":[22],"Catalase,":[23],"L":[24],"ALpha-hydroxy":[25],"acid":[26,59,81,94],"oxidase,":[27,52],"isocitrate":[28],"dehydrogenase,":[29],"glycerophosphate":[30],"dehydrogenase":[31,34],"lactate":[33],"were":[35,61],"easily":[36],"released":[37],"from":[38],"particles":[40],"during":[41],"their":[42],"lysis":[43],"treatment":[45],"with":[46,97],"0.16":[47],"M":[48],"KCl,":[49],"whereas":[50],"urate":[51,98],"NADH":[53],"cytochrome":[54],"c":[55],"reductase":[56],"D-amino":[58,93],"oxidase":[60,82,95,99],"not":[62],"solubilized.":[63],"After":[64],"solubilization":[66],"peroxisomal":[68,102],"membrane":[69],"by":[70],"0.2%":[71],"Triton":[72],"X-100,":[73],"remaining":[75],"core":[76],"contained":[77],"about":[78],"50%":[79],"amino":[80],"activity,":[83],"had":[85],"1.28--1.30":[86],"g/cm3":[87],"density.":[88],"These":[89],"results":[90],"suggest":[91],"that":[92],"associates":[96],"core.":[103]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-07-22T00:00:00"}