{"id":"https://openalex.org/W2467296285","doi":"https://doi.org/10.4137/bic.s31801","title":"Quantitative Perfusion and Permeability Biomarkers in Brain Cancer from Tomographic CT and MR Images","display_name":"Quantitative Perfusion and Permeability Biomarkers in Brain Cancer from Tomographic CT and MR Images","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2467296285","doi":"https://doi.org/10.4137/bic.s31801","mag":"2467296285","pmid":"https://pubmed.ncbi.nlm.nih.gov/27398030","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4933536"},"language":"en","primary_location":{"id":"doi:10.4137/bic.s31801","doi":"https://doi.org/10.4137/bic.s31801","is_oa":true,"landing_page_url":"https://doi.org/10.4137/bic.s31801","pdf_url":"https://journals.sagepub.com/doi/pdf/10.4137/BIC.S31801","source":{"id":"https://openalex.org/S4210234771","display_name":"Biomarkers in Cancer","issn_l":"1179-299X","issn":["1179-299X"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers in Cancer","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://journals.sagepub.com/doi/pdf/10.4137/BIC.S31801","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073131485","display_name":"Armin Eilaghi","orcid":"https://orcid.org/0000-0001-7238-8938","observed_orcids":["https://orcid.org/0000-0001-7238-8938"]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I2802418778","display_name":"Foothills Medical Centre","ror":"https://ror.org/020wfrz93","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2802418778"]},{"id":"https://openalex.org/I4405260330","display_name":"Hotchkiss Brain Institute","ror":"https://ror.org/03k51z204","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Armin Eilaghi","raw_affiliation_strings":["Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada","Department of Radiology, University of Calgary, Calgary, AB, Canada","Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada","Seaman Family MR Centre, Foothills Medical Centre, Calgary, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Department of Radiology, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]},{"raw_affiliation_string":"Seaman Family MR Centre, Foothills Medical Centre, Calgary, AB, Canada","institution_ids":["https://openalex.org/I2802418778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061256212","display_name":"Timothy Pok Chi Yeung","orcid":"https://orcid.org/0000-0003-0036-7403","observed_orcids":["https://orcid.org/0000-0003-0036-7403"]},"institutions":[{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]},{"id":"https://openalex.org/I4405252475","display_name":"Robarts Research Institute","ror":"https://ror.org/01psf3m26","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Timothy Yeung","raw_affiliation_strings":["Lawson Health Research Institute and Robarts Research Institute, London, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lawson Health Research Institute and Robarts Research Institute, London, ON, Canada","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4405252475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076869426","display_name":"Christopher D. d\u2019Esterre","orcid":"https://orcid.org/0000-0001-5568-9325","observed_orcids":["https://orcid.org/0000-0001-5568-9325"]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I2802418778","display_name":"Foothills Medical Centre","ror":"https://ror.org/020wfrz93","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2802418778"]},{"id":"https://openalex.org/I4405260330","display_name":"Hotchkiss Brain Institute","ror":"https://ror.org/03k51z204","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Christopher d'Esterre","raw_affiliation_strings":["Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada","Department of Radiology, University of Calgary, Calgary, AB, Canada","Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada","Seaman Family MR Centre, Foothills Medical Centre, Calgary, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Department of Radiology, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]},{"raw_affiliation_string":"Seaman Family MR Centre, Foothills Medical Centre, Calgary, AB, Canada","institution_ids":["https://openalex.org/I2802418778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019768466","display_name":"Glenn S. Bauman","orcid":"https://orcid.org/0000-0002-5279-7360","observed_orcids":["https://orcid.org/0000-0002-5279-7360"]},"institutions":[{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]},{"id":"https://openalex.org/I4405252475","display_name":"Robarts Research Institute","ror":"https://ror.org/01psf3m26","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Glenn Bauman","raw_affiliation_strings":["Lawson Health Research Institute and Robarts Research Institute, London, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lawson Health Research Institute and Robarts Research Institute, London, ON, Canada","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4405252475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047265985","display_name":"Slav Yartsev","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]},{"id":"https://openalex.org/I4405252475","display_name":"Robarts Research Institute","ror":"https://ror.org/01psf3m26","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Slav Yartsev","raw_affiliation_strings":["Lawson Health Research Institute and Robarts Research Institute, London, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lawson Health Research Institute and Robarts Research Institute, London, ON, Canada","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4405252475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106393366","display_name":"Jay Easaw","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jay Easaw","raw_affiliation_strings":["Department of Oncology, University of Calgary, Calgary, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111601032","display_name":"Enrico Fainardi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]},{"id":"https://openalex.org/I4210126260","display_name":"Arcispedale Sant'Anna","ror":"https://ror.org/026yzxh70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210126260"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Enrico Fainardi","raw_affiliation_strings":["Neuroradiology Unit, Department of Neurosciences and Rehabilitation, Azienda Ospedaliero-Universitaria, Arcispedale S. Anna, Ferrara, Italy","Neuroradiology Unit, Department of Radiology, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroradiology Unit, Department of Neurosciences and Rehabilitation, Azienda Ospedaliero-Universitaria, Arcispedale S. Anna, Ferrara, Italy","institution_ids":["https://openalex.org/I4210126260"]},{"raw_affiliation_string":"Neuroradiology Unit, Department of Radiology, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013499153","display_name":"Ting\u2010Yim Lee","orcid":"https://orcid.org/0000-0001-7605-9752","observed_orcids":["https://orcid.org/0000-0001-7605-9752"]},"institutions":[{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]},{"id":"https://openalex.org/I4405252475","display_name":"Robarts Research Institute","ror":"https://ror.org/01psf3m26","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ting-Yim Lee","raw_affiliation_strings":["Lawson Health Research Institute and Robarts Research Institute, London, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lawson Health Research Institute and Robarts Research Institute, London, ON, Canada","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4405252475"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085398611","display_name":"Richard Frayne","orcid":"https://orcid.org/0000-0003-0358-1210","observed_orcids":["https://orcid.org/0000-0003-0358-1210"]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I2802418778","display_name":"Foothills Medical Centre","ror":"https://ror.org/020wfrz93","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2802418778"]},{"id":"https://openalex.org/I4405260330","display_name":"Hotchkiss Brain Institute","ror":"https://ror.org/03k51z204","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Richard Frayne","raw_affiliation_strings":["Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada","Department of Radiology, University of Calgary, Calgary, AB, Canada","Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada","Seaman Family MR Centre, Foothills Medical Centre, Calgary, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Department of Radiology, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]},{"raw_affiliation_string":"Seaman Family MR Centre, Foothills Medical Centre, Calgary, AB, Canada","institution_ids":["https://openalex.org/I2802418778"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5085398611"],"corresponding_institution_ids":["https://openalex.org/I168635309","https://openalex.org/I2802418778","https://openalex.org/I4405260330"],"apc_list":null,"apc_paid":null,"fwci":0.0696,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.07480398,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"8s2","issue":"Suppl 2","first_page":"BIC.S31801","last_page":"BIC.S31801"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.5630000233650208,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.5630000233650208,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.16210000216960907,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.094200000166893,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dynamic-contrast-enhanced-imaging","display_name":"dynamic contrast-enhanced imaging","score":0.8479999899864197},{"id":"https://openalex.org/keywords/perfusion-imaging","display_name":"perfusion imaging","score":0.8870000243186951},{"id":"https://openalex.org/keywords/blood-brain-barrier-permeability","display_name":"blood-brain barrier permeability","score":0.9160000085830688},{"id":"https://openalex.org/keywords/brain-tumors","display_name":"brain tumors","score":0.671999990940094},{"id":"https://openalex.org/keywords/high-grade-glioma","display_name":"high-grade glioma","score":0.843999981880188},{"id":"https://openalex.org/keywords/treatment-response-monitoring","display_name":"treatment response monitoring","score":0.6759999990463257},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6389999985694885},{"id":"https://openalex.org/keywords/anti-angiogenic-therapy","display_name":"anti-angiogenic therapy","score":0.7549999952316284},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.6660000085830688},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.8659999966621399},{"id":"https://openalex.org/keywords/survival-prediction","display_name":"survival prediction","score":0.6610000133514404},{"id":"https://openalex.org/keywords/treatment-planning","display_name":"treatment planning","score":0.3840000033378601}],"concepts":[{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.7067550420761108},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.696188747882843},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6856909394264221},{"id":"https://openalex.org/C135691158","wikidata":"https://www.wikidata.org/wiki/Q7168308","display_name":"Perfusion scanning","level":3,"score":0.6407232284545898},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.544762134552002},{"id":"https://openalex.org/C113045295","wikidata":"https://www.wikidata.org/wiki/Q7916465","display_name":"Vascular permeability","level":2,"score":0.5242027044296265},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.5165807008743286},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.5132903456687927},{"id":"https://openalex.org/C37557685","wikidata":"https://www.wikidata.org/wiki/Q1896673","display_name":"Blood volume","level":2,"score":0.5027902126312256},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.49755385518074036},{"id":"https://openalex.org/C196822366","wikidata":"https://www.wikidata.org/wiki/Q270524","display_name":"Parenchyma","level":2,"score":0.4719967842102051},{"id":"https://openalex.org/C120882062","wikidata":"https://www.wikidata.org/wiki/Q28352","display_name":"Permeability (electromagnetism)","level":3,"score":0.4541766345500946},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.4453403651714325},{"id":"https://openalex.org/C2779130545","wikidata":"https://www.wikidata.org/wiki/Q233309","display_name":"Brain tumor","level":2,"score":0.4197227358818054},{"id":"https://openalex.org/C2994142346","wikidata":"https://www.wikidata.org/wiki/Q353268","display_name":"Dynamic contrast","level":3,"score":0.415092408657074},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.41410359740257263},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3892304599285126},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.33726194500923157},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13024550676345825},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.09300613403320312},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":9,"locations":[{"id":"doi:10.4137/bic.s31801","doi":"https://doi.org/10.4137/bic.s31801","is_oa":true,"landing_page_url":"https://doi.org/10.4137/bic.s31801","pdf_url":"https://journals.sagepub.com/doi/pdf/10.4137/BIC.S31801","source":{"id":"https://openalex.org/S4210234771","display_name":"Biomarkers in Cancer","issn_l":"1179-299X","issn":["1179-299X"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers in Cancer","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3904740","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4933536","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:27398030","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27398030","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers in cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4933536","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4933536/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomark Cancer","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:83fd579c60ab48e6919a60ce0b4711af","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/83fd579c60ab48e6919a60ce0b4711af","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomarkers in Cancer, Vol 8s2 (2016)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:df3aa5fc6a0841a7b0df925961f870b2","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/df3aa5fc6a0841a7b0df925961f870b2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomarkers in Cancer, Vol 2016, Iss Suppl. 2, Pp 47-59 (2016)","raw_type":"article"},{"id":"pmh:oai:flore.unifi.it:2158/1103398","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2158/1103398","pdf_url":null,"source":{"id":"https://openalex.org/S4306402033","display_name":"Florence Research (University of Florence)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45084792","host_organization_name":"University of Florence","host_organization_lineage":["https://openalex.org/I45084792"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:flore.unifi.it:2158/1139102","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2158/1139102","pdf_url":null,"source":{"id":"https://openalex.org/S4306402033","display_name":"Florence Research (University of Florence)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45084792","host_organization_name":"University of Florence","host_organization_lineage":["https://openalex.org/I45084792"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:libertasacademica.com/5740","doi":null,"is_oa":false,"landing_page_url":"http://insights.sagepub.com/redirect_file.php?fileId=7639&filename=5740-BIC-Quantitative-Perfusion-and-Permeability-Biomarkers-in-Brain-Cancer-fro.pdf&fileType=pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://insights.sagepub.com/quantitative-perfusion-and-permeability-biomarkers-in-brain-cancer-fro-article-a5740","raw_type":null}],"best_oa_location":{"id":"doi:10.4137/bic.s31801","doi":"https://doi.org/10.4137/bic.s31801","is_oa":true,"landing_page_url":"https://doi.org/10.4137/bic.s31801","pdf_url":"https://journals.sagepub.com/doi/pdf/10.4137/BIC.S31801","source":{"id":"https://openalex.org/S4210234771","display_name":"Biomarkers in Cancer","issn_l":"1179-299X","issn":["1179-299X"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomarkers in Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2467296285.pdf"},"referenced_works_count":116,"referenced_works":["https://openalex.org/W23426813","https://openalex.org/W110679595","https://openalex.org/W232170561","https://openalex.org/W313973297","https://openalex.org/W1560814177","https://openalex.org/W1624957772","https://openalex.org/W1893588436","https://openalex.org/W1922824775","https://openalex.org/W1944705852","https://openalex.org/W1959628099","https://openalex.org/W1965493282","https://openalex.org/W1970203323","https://openalex.org/W1972423289","https://openalex.org/W1972526069","https://openalex.org/W1974003523","https://openalex.org/W1975371010","https://openalex.org/W1976833053","https://openalex.org/W1977549251","https://openalex.org/W1978223237","https://openalex.org/W1984134781","https://openalex.org/W1985341993","https://openalex.org/W1985978765","https://openalex.org/W1986186581","https://openalex.org/W1986800076","https://openalex.org/W1988850064","https://openalex.org/W1994554829","https://openalex.org/W1999946694","https://openalex.org/W2008525396","https://openalex.org/W2009633034","https://openalex.org/W2019865884","https://openalex.org/W2020784028","https://openalex.org/W2026359197","https://openalex.org/W2031561757","https://openalex.org/W2032246527","https://openalex.org/W2033089300","https://openalex.org/W2034599771","https://openalex.org/W2037529037","https://openalex.org/W2039585276","https://openalex.org/W2041399543","https://openalex.org/W2041481362","https://openalex.org/W2041532314","https://openalex.org/W2042083282","https://openalex.org/W2042098439","https://openalex.org/W2043692938","https://openalex.org/W2052455429","https://openalex.org/W2053686058","https://openalex.org/W2056829262","https://openalex.org/W2059051635","https://openalex.org/W2062594348","https://openalex.org/W2063798166","https://openalex.org/W2066301450","https://openalex.org/W2066419144","https://openalex.org/W2066907008","https://openalex.org/W2074145540","https://openalex.org/W2076725220","https://openalex.org/W2080157863","https://openalex.org/W2080505000","https://openalex.org/W2081119236","https://openalex.org/W2082500638","https://openalex.org/W2088317370","https://openalex.org/W2091011326","https://openalex.org/W2092078486","https://openalex.org/W2094802222","https://openalex.org/W2095365904","https://openalex.org/W2096287682","https://openalex.org/W2096882618","https://openalex.org/W2097181552","https://openalex.org/W2099242902","https://openalex.org/W2099906722","https://openalex.org/W2100435375","https://openalex.org/W2100481498","https://openalex.org/W2100714292","https://openalex.org/W2112268717","https://openalex.org/W2112957672","https://openalex.org/W2114967314","https://openalex.org/W2116641010","https://openalex.org/W2117278204","https://openalex.org/W2118311655","https://openalex.org/W2124089189","https://openalex.org/W2124441852","https://openalex.org/W2124538292","https://openalex.org/W2125053937","https://openalex.org/W2125647485","https://openalex.org/W2126262617","https://openalex.org/W2126568303","https://openalex.org/W2132168322","https://openalex.org/W2134420328","https://openalex.org/W2135368782","https://openalex.org/W2137762696","https://openalex.org/W2141171960","https://openalex.org/W2142104626","https://openalex.org/W2147535764","https://openalex.org/W2148132443","https://openalex.org/W2148977460","https://openalex.org/W2150721101","https://openalex.org/W2152353759","https://openalex.org/W2155146490","https://openalex.org/W2157872540","https://openalex.org/W2160290709","https://openalex.org/W2162184131","https://openalex.org/W2162643152","https://openalex.org/W2163203871","https://openalex.org/W2163298126","https://openalex.org/W2163554796","https://openalex.org/W2165448374","https://openalex.org/W2167293680","https://openalex.org/W2169144207","https://openalex.org/W2169961966","https://openalex.org/W2171994473","https://openalex.org/W2186582486","https://openalex.org/W2219978888","https://openalex.org/W2339319747","https://openalex.org/W2375878541","https://openalex.org/W2413452454","https://openalex.org/W4244244128","https://openalex.org/W4293529598"],"related_works":["https://openalex.org/W2119013933","https://openalex.org/W2078409717","https://openalex.org/W2069877386","https://openalex.org/W2087653797","https://openalex.org/W15726272","https://openalex.org/W2608904475","https://openalex.org/W2144746276","https://openalex.org/W2271138928","https://openalex.org/W4214949627","https://openalex.org/W6991547467"],"abstract_inverted_index":{"Dynamic":[0],"contrast-enhanced":[1,91],"perfusion":[2,92],"and":[3,9,21,27,37,52,71,87,93,104,125,131],"permeability":[4,40,94],"imaging,":[5],"using":[6],"computed":[7,88],"tomography":[8,89],"magnetic":[10,85],"resonance":[11,86],"systems,":[12],"are":[13,96,134],"important":[14],"techniques":[15,30,110],"for":[16,111],"assessing":[17],"the":[18,63,76,82,105],"vascular":[19],"supply":[20],"hemodynamics":[22],"of":[23,75,84,108],"healthy":[24],"brain":[25,117],"parenchyma":[26],"tumors.":[28],"These":[29,55],"can":[31],"measure":[32],"blood":[33,35],"flow,":[34],"volume,":[36],"blood-brain":[38],"barrier":[39],"surface":[41],"area":[42],"product":[43],"and,":[44],"thus,":[45],"may":[46],"provide":[47],"information":[48],"complementary":[49],"to":[50,61,67,72],"clinical":[51],"pathological":[53],"assessments.":[54],"have":[56],"been":[57],"used":[58],"as":[59],"biomarkers":[60],"enhance":[62],"treatment":[64,69,77],"planning":[65],"process,":[66],"optimize":[68],"decision-making,":[70],"enable":[73],"monitoring":[74],"noninvasively.":[78],"In":[79],"this":[80],"review,":[81],"principles":[83],"dynamic":[90],"imaging":[95],"described":[97],"(with":[98],"an":[99],"emphasis":[100],"on":[101],"their":[102],"commonalities),":[103],"potential":[106],"values":[107],"these":[109],"differentiating":[112],"high-grade":[113],"gliomas":[114],"from":[115,122],"other":[116],"lesions,":[118],"distinguishing":[119],"true":[120],"progression":[121],"posttreatment":[123],"effects,":[124],"predicting":[126],"survival":[127],"after":[128],"radiotherapy,":[129],"chemotherapy,":[130],"antiangiogenic":[132],"treatments":[133],"presented.":[135]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-07-22T00:00:00"}