{"id":"https://openalex.org/W246456751","doi":null,"title":"Role of oxidative injury in affecting the foetal & placental weights on exposure to tobacco smoke.","display_name":"Role of oxidative injury in affecting the foetal & placental weights on exposure to tobacco smoke.","publication_year":2015,"publication_date":"2015-04-01","ids":{"openalex":"https://openalex.org/W246456751","mag":"246456751","pmid":"https://pubmed.ncbi.nlm.nih.gov/25976572"},"language":"en","primary_location":{"id":"pmid:25976572","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25976572","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JPMA. The Journal of the Pakistan Medical Association","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104094571","display_name":"Huma Musarrat Khan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801712768","display_name":"Foundation University Medical College","ror":"https://ror.org/020jkns84","country_code":"PK","type":"education","lineage":["https://openalex.org/I2801712768"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Huma Musarrat Khan","raw_affiliation_strings":["Department of Anatomy, Foundation University Medical College"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Foundation University Medical College","institution_ids":["https://openalex.org/I2801712768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111060383","display_name":"Muhammad Yunus Khan","orcid":"https://orcid.org/0009-0009-3309-3147","observed_orcids":["https://orcid.org/0009-0009-3309-3147"]},"institutions":[{"id":"https://openalex.org/I2801020214","display_name":"College of Physicians and Surgeons Pakistan","ror":"https://ror.org/0039pbm21","country_code":"PK","type":"education","lineage":["https://openalex.org/I2801020214"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Muhammad Yunus Khan","raw_affiliation_strings":["Department of Anatomy, CPSP Regional Center Islamabad"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, CPSP Regional Center Islamabad","institution_ids":["https://openalex.org/I2801020214"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112183637","display_name":"Liaqat Ali Minhas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Liaqat Ali Minhas","raw_affiliation_strings":["Rawal Institute of Medical Sciences, Rawalpindi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rawal Institute of Medical Sciences, Rawalpindi","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3277,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.63880515,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"65","issue":"4","first_page":"383","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.67330002784729,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.67330002784729,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.23080000281333923,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.07240000367164612,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prenatal-tobacco-exposure","display_name":"prenatal tobacco exposure","score":0.859000027179718},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8149999976158142},{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.8009999990463257},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.6679999828338623},{"id":"https://openalex.org/keywords/vitamin-supplementation","display_name":"vitamin supplementation","score":0.9150000214576721},{"id":"https://openalex.org/keywords/fetal-weight","display_name":"fetal weight","score":0.8899999856948853},{"id":"https://openalex.org/keywords/placental-weight","display_name":"placental weight","score":1.0},{"id":"https://openalex.org/keywords/placenta","display_name":"placenta","score":0.5860000252723694},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.3619999885559082},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8124426603317261},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.5678329467773438},{"id":"https://openalex.org/C2778355491","wikidata":"https://www.wikidata.org/wiki/Q2386268","display_name":"Tobacco smoke","level":2,"score":0.5324909090995789},{"id":"https://openalex.org/C2993351451","wikidata":"https://www.wikidata.org/wiki/Q2386268","display_name":"Cigarette smoke","level":2,"score":0.508922815322876},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.4363487660884857},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.435308575630188},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.3734856843948364},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.371346116065979},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3600468337535858},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35215455293655396},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.3247101306915283},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1323569416999817},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010929","descriptor_name":"Placentation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014028","descriptor_name":"Tobacco Smoke Pollution","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D014815","descriptor_name":"Vitamins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020011","descriptor_name":"Protective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D020567","descriptor_name":"Fetal Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D049188","descriptor_name":"Prenatal Injuries","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D049188","descriptor_name":"Prenatal Injuries","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D049188","descriptor_name":"Prenatal Injuries","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:25976572","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25976572","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JPMA. The Journal of the Pakistan Medical Association","raw_type":"Journal Article"},{"id":"mag:246456751","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25976572","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1772525138","https://openalex.org/W1924451767","https://openalex.org/W1964304628","https://openalex.org/W1980247788","https://openalex.org/W1985573886","https://openalex.org/W2024706817","https://openalex.org/W2033898136","https://openalex.org/W2039109269","https://openalex.org/W2052840575","https://openalex.org/W2059107557","https://openalex.org/W2072855036","https://openalex.org/W2086453933","https://openalex.org/W2089955483","https://openalex.org/W2091218738","https://openalex.org/W2100155139","https://openalex.org/W2104991520","https://openalex.org/W2119701631","https://openalex.org/W2153126087","https://openalex.org/W2159232369","https://openalex.org/W2184458594","https://openalex.org/W2268023181","https://openalex.org/W2311215963","https://openalex.org/W2397481123","https://openalex.org/W2412368050"],"related_works":["https://openalex.org/W2184458594","https://openalex.org/W2556665795","https://openalex.org/W2318019193","https://openalex.org/W1976946444","https://openalex.org/W2060425781","https://openalex.org/W1990308536","https://openalex.org/W2431039229","https://openalex.org/W2139341308","https://openalex.org/W68275551","https://openalex.org/W2102330748"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"investigate":[2],"the":[3,68,97,102,121,155,231,249,256,272],"role":[4],"of":[5,33,39,223,285],"oxidative":[6,265],"injury":[7,266],"in":[8,14,82,141,161,172,179,196,230,271],"affecting":[9],"foetal":[10,122,159,177,225,251],"and":[11,74,89,101,104,120,143,226,235,252,255],"placental":[12,123,194,228,253],"weights":[13,229,254],"mice":[15,35,57,151],"by":[16,268,282],"exposing":[17],"them":[18],"to":[19,53,78,245,264,279],"tobacco":[20,80,246,273],"smoke":[21,81,247,274],"with":[22,26,88,92],"or":[23],"without":[24,90],"supplementation":[25,91],"antioxidants.":[27,286],"METHODS:":[28],"The":[29,56,108,113,157,175,192,221],"randomized":[30],"control":[31],"trial":[32],"pregnant":[34],"at":[36,43],"day":[37],"one":[38],"gestation":[40],"was":[41,125,129,164,167,182,185,199,202,214],"conducted":[42],"Anatomy":[44],"Department":[45],"CPSP":[46],"Regional":[47],"Center":[48],"Islamabad,":[49],"from":[50,189],"March":[51],"2005":[52],"October":[54],"2005.":[55],"were":[58,76,99,106,111,118,136,237],"divided":[59],"into":[60],"three":[61],"groups:":[62],"Group":[63,147,162,173,180,197,207,211,218],"C":[64,148,208],"had":[65,149],"controls,":[66],"while":[67,146],"two":[69],"other":[70],"groups,":[71,145],"groups":[72,232],"S":[73,142,163,190,198,219,234],"SV":[75,144,181,212,236],"exposed":[77],"secondary":[79],"a":[83],"whole":[84],"body":[85],"exposure":[86,244],"chamber":[87],"vitamins":[93],"respectively.":[94,241],"At":[95],"term,":[96],"animals":[98],"sacrificed":[100],"placentae":[103],"foetuses":[105],"weighed.":[107],"average":[109],"values":[110],"calculated.":[112,126],"means":[114],"for":[115,131],"each":[116,140],"group":[117],"analysed":[119],"ratio":[124,222],"SPSS":[127],"17":[128],"used":[130],"statistical":[132],"analysis.":[133],"RESULTS:":[134],"There":[135],"44":[137],"mice;":[138],"15(34%)":[139],"14(32%)":[150],"who":[152],"acted":[153],"as":[154,275],"controls.":[156],"mean":[158,176,193,224,227,250],"weight":[160,178,195],"0.65\u00b10.52g":[165],"which":[166,184,201],"significantly":[168,187,203,215],"less":[169,204],"(p<0.0001)":[170],"than1.48\u00b10.19g":[171],"C.":[174],"0.97\u00b10.65g":[183],"not":[186],"different":[188],"(p=0.124).":[191],"0.16\u00b10.02g":[200],"than":[205,217],"0.21\u00b10.05gin":[206],"(p=0.014).":[209],"In":[210],"it":[213,276],"more":[216],"(p<0.0001).":[220],"C,":[233],"7.05,":[238],"3.92":[239],"and4.41":[240],"CONCLUSIONS:":[242],"Prenatal":[243],"decreased":[248],"foetal-placental":[257],"ratio.":[258],"This":[259],"may":[260],"partly":[261],"be":[262],"attributed":[263],"induced":[267],"free":[269],"radicals":[270],"is":[277],"prevented":[278],"some":[280],"extent":[281],"simultaneous":[283],"administration":[284]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}