{"id":"https://openalex.org/W2463698338","doi":"https://doi.org/10.1007/978-3-319-06713-1_8","title":"Inflammation and Sickle Cell Anemia","display_name":"Inflammation and Sickle Cell Anemia","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2463698338","doi":"https://doi.org/10.1007/978-3-319-06713-1_8","mag":"2463698338"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-06713-1_8","doi":"https://doi.org/10.1007/978-3-319-06713-1_8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-06713-1_8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sickle Cell Anemia","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4243124425","display_name":"Sickle Cell Anemia"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036974436","display_name":"Camila Bononi Almeida","orcid":"https://orcid.org/0000-0002-1253-2165","observed_orcids":["https://orcid.org/0000-0002-1253-2165"]},"institutions":[{"id":"https://openalex.org/I2800288331","display_name":"Hospital Israelita Albert Einstein","ror":"https://ror.org/04cwrbc27","country_code":"BR","type":"funder","lineage":["https://openalex.org/I2800288331"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Camila Bononi de Almeida","raw_affiliation_strings":["Instituto Israelita de Ensino e Pesquisa Albert Einstein, Hospital Israelita Albert Einstein, S\u00e3o Paulo, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Israelita de Ensino e Pesquisa Albert Einstein, Hospital Israelita Albert Einstein, S\u00e3o Paulo, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I2800288331"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066832003","display_name":"Gregory James Kato","orcid":"https://orcid.org/0000-0003-4465-3217","observed_orcids":["https://orcid.org/0000-0003-4465-3217"]},"institutions":[{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory J. Kato","raw_affiliation_strings":["Sickle Cell Center of Excellence, University of Pittsburgh Medical Center, Pittsburgh, PA, 15261, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sickle Cell Center of Excellence, University of Pittsburgh Medical Center, Pittsburgh, PA, 15261, USA","institution_ids":["https://openalex.org/I4210134769"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067515209","display_name":"Nicola Conran","orcid":"https://orcid.org/0000-0001-5726-7919","observed_orcids":["https://orcid.org/0000-0001-5726-7919"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Nicola Conran","raw_affiliation_strings":["Hematology Center, School of Medical Science, University of Campinas \u2013 UNICAMP, Campinas, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology Center, School of Medical Science, University of Campinas \u2013 UNICAMP, Campinas, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I181391015"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5067515209"],"corresponding_institution_ids":["https://openalex.org/I181391015"],"apc_list":null,"apc_paid":null,"fwci":4.7572,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.94640943,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"177","last_page":"211"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sickle-cell-disease","display_name":"sickle cell disease","score":0.9980000257492065},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7950000166893005},{"id":"https://openalex.org/keywords/vaso-occlusive-crisis","display_name":"vaso-occlusive crisis","score":0.8989999890327454},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.8730000257492065},{"id":"https://openalex.org/keywords/damage-associated-molecular-patterns","display_name":"damage-associated molecular patterns","score":0.9729999899864197},{"id":"https://openalex.org/keywords/chronic-inflammation","display_name":"chronic inflammation","score":0.7260000109672546},{"id":"https://openalex.org/keywords/hydroxyurea","display_name":"hydroxyurea","score":0.8730000257492065},{"id":"https://openalex.org/keywords/anti-inflammatory-therapy","display_name":"anti-inflammatory therapy","score":0.921999990940094},{"id":"https://openalex.org/keywords/sickle-red-blood-cells","display_name":"sickle red blood cells","score":0.7860000133514404},{"id":"https://openalex.org/keywords/hemolysis","display_name":"hemolysis","score":0.8610000014305115},{"id":"https://openalex.org/keywords/leukocyte-recruitment","display_name":"leukocyte recruitment","score":0.7919999957084656},{"id":"https://openalex.org/keywords/acute-chest-syndrome","display_name":"acute chest syndrome","score":0.6539999842643738},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.6880000233650208}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7936325073242188},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.7119967937469482},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.6788681745529175},{"id":"https://openalex.org/C2778620579","wikidata":"https://www.wikidata.org/wiki/Q185034","display_name":"Sickle cell anemia","level":3,"score":0.5875680446624756},{"id":"https://openalex.org/C2779902561","wikidata":"https://www.wikidata.org/wiki/Q471706","display_name":"Hemolysis","level":2,"score":0.5614665150642395},{"id":"https://openalex.org/C2780441568","wikidata":"https://www.wikidata.org/wiki/Q7916864","display_name":"Vaso-occlusive crisis","level":4,"score":0.5429214835166931},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5185444951057434},{"id":"https://openalex.org/C2780976302","wikidata":"https://www.wikidata.org/wiki/Q4677915","display_name":"Acute chest syndrome","level":4,"score":0.506334662437439},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.48817306756973267},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4300031363964081},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22734704613685608}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-319-06713-1_8","doi":"https://doi.org/10.1007/978-3-319-06713-1_8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-06713-1_8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sickle Cell Anemia","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":213,"referenced_works":["https://openalex.org/W2671029","https://openalex.org/W13114315","https://openalex.org/W47071877","https://openalex.org/W55056942","https://openalex.org/W94248761","https://openalex.org/W155387552","https://openalex.org/W187097231","https://openalex.org/W187823094","https://openalex.org/W204998232","https://openalex.org/W1490560016","https://openalex.org/W1526630390","https://openalex.org/W1540512844","https://openalex.org/W1541939279","https://openalex.org/W1553258707","https://openalex.org/W1563116489","https://openalex.org/W1575154971","https://openalex.org/W1604761302","https://openalex.org/W1633660980","https://openalex.org/W1671726658","https://openalex.org/W1735133062","https://openalex.org/W1783198039","https://openalex.org/W1834629292","https://openalex.org/W1855316965","https://openalex.org/W1870573284","https://openalex.org/W1912656294","https://openalex.org/W1924703325","https://openalex.org/W1926932414","https://openalex.org/W1955305991","https://openalex.org/W1964249139","https://openalex.org/W1967541128","https://openalex.org/W1968215721","https://openalex.org/W1968512491","https://openalex.org/W1969576341","https://openalex.org/W1974954205","https://openalex.org/W1977902516","https://openalex.org/W1978407650","https://openalex.org/W1979240926","https://openalex.org/W1979412100","https://openalex.org/W1980573671","https://openalex.org/W1980814594","https://openalex.org/W1980917698","https://openalex.org/W1981064726","https://openalex.org/W1981236618","https://openalex.org/W1981340903","https://openalex.org/W1981357811","https://openalex.org/W1984887661","https://openalex.org/W1985442806","https://openalex.org/W1986117502","https://openalex.org/W1988155241","https://openalex.org/W1988288321","https://openalex.org/W1991664249","https://openalex.org/W1993539946","https://openalex.org/W1996394439","https://openalex.org/W1999948518","https://openalex.org/W2001961608","https://openalex.org/W2003053340","https://openalex.org/W2003996101","https://openalex.org/W2005053160","https://openalex.org/W2006256646","https://openalex.org/W2006754069","https://openalex.org/W2007223732","https://openalex.org/W2007555505","https://openalex.org/W2007874528","https://openalex.org/W2008752209","https://openalex.org/W2009936217","https://openalex.org/W2010836598","https://openalex.org/W2010943728","https://openalex.org/W2011527402","https://openalex.org/W2014093734","https://openalex.org/W2014867851","https://openalex.org/W2015181601","https://openalex.org/W2016237453","https://openalex.org/W2018424384","https://openalex.org/W2018519248","https://openalex.org/W2018565869","https://openalex.org/W2019449116","https://openalex.org/W2019614174","https://openalex.org/W2020634990","https://openalex.org/W2021850499","https://openalex.org/W2022882100","https://openalex.org/W2024241294","https://openalex.org/W2024939795","https://openalex.org/W2026063712","https://openalex.org/W2026254409","https://openalex.org/W2026448131","https://openalex.org/W2026891878","https://openalex.org/W2027350051","https://openalex.org/W2027459471","https://openalex.org/W2027955104","https://openalex.org/W2028236795","https://openalex.org/W2030851049","https://openalex.org/W2031084334","https://openalex.org/W2031330301","https://openalex.org/W2032227357","https://openalex.org/W2034914402","https://openalex.org/W2035346271","https://openalex.org/W2035430913","https://openalex.org/W2036782492","https://openalex.org/W2037581234","https://openalex.org/W2038661530","https://openalex.org/W2040024980","https://openalex.org/W2040042755","https://openalex.org/W2040323431","https://openalex.org/W2041008947","https://openalex.org/W2042235665","https://openalex.org/W2042851093","https://openalex.org/W2043251376","https://openalex.org/W2044183384","https://openalex.org/W2044505929","https://openalex.org/W2046509298","https://openalex.org/W2047025675","https://openalex.org/W2048066714","https://openalex.org/W2049049472","https://openalex.org/W2049129790","https://openalex.org/W2050611373","https://openalex.org/W2051114755","https://openalex.org/W2051759508","https://openalex.org/W2051844111","https://openalex.org/W2052525169","https://openalex.org/W2053889157","https://openalex.org/W2055772077","https://openalex.org/W2055848370","https://openalex.org/W2056584805","https://openalex.org/W2057257459","https://openalex.org/W2058764214","https://openalex.org/W2062828619","https://openalex.org/W2063416975","https://openalex.org/W2063780946","https://openalex.org/W2064303583","https://openalex.org/W2064598070","https://openalex.org/W2066856450","https://openalex.org/W2066865593","https://openalex.org/W2067770510","https://openalex.org/W2070251534","https://openalex.org/W2072813591","https://openalex.org/W2073821065","https://openalex.org/W2074901521","https://openalex.org/W2075981185","https://openalex.org/W2076539822","https://openalex.org/W2077940334","https://openalex.org/W2078506890","https://openalex.org/W2079333020","https://openalex.org/W2079362390","https://openalex.org/W2081861029","https://openalex.org/W2082268007","https://openalex.org/W2084688358","https://openalex.org/W2085961346","https://openalex.org/W2089273197","https://openalex.org/W2089600954","https://openalex.org/W2089864728","https://openalex.org/W2090450186","https://openalex.org/W2090689552","https://openalex.org/W2091647374","https://openalex.org/W2092186941","https://openalex.org/W2092572278","https://openalex.org/W2096936713","https://openalex.org/W2098272848","https://openalex.org/W2098776090","https://openalex.org/W2098847286","https://openalex.org/W2099411992","https://openalex.org/W2100360129","https://openalex.org/W2108267327","https://openalex.org/W2109880818","https://openalex.org/W2111176771","https://openalex.org/W2111453087","https://openalex.org/W2113023385","https://openalex.org/W2114872207","https://openalex.org/W2115068232","https://openalex.org/W2118531218","https://openalex.org/W2118742454","https://openalex.org/W2119859914","https://openalex.org/W2122039897","https://openalex.org/W2125247175","https://openalex.org/W2125425147","https://openalex.org/W2126649096","https://openalex.org/W2127860753","https://openalex.org/W2128017989","https://openalex.org/W2129935236","https://openalex.org/W2132078656","https://openalex.org/W2132736072","https://openalex.org/W2133445175","https://openalex.org/W2133496985","https://openalex.org/W2137102515","https://openalex.org/W2137359256","https://openalex.org/W2137639629","https://openalex.org/W2137979583","https://openalex.org/W2138889414","https://openalex.org/W2140044845","https://openalex.org/W2145194552","https://openalex.org/W2145946501","https://openalex.org/W2147182596","https://openalex.org/W2150594596","https://openalex.org/W2155652067","https://openalex.org/W2158519357","https://openalex.org/W2160219813","https://openalex.org/W2161677619","https://openalex.org/W2166262520","https://openalex.org/W2167271197","https://openalex.org/W2171564382","https://openalex.org/W2289512502","https://openalex.org/W2302447608","https://openalex.org/W2313541759","https://openalex.org/W2315662306","https://openalex.org/W2322074970","https://openalex.org/W2324788201","https://openalex.org/W2332694299","https://openalex.org/W2336959523","https://openalex.org/W2398489281","https://openalex.org/W2405940089","https://openalex.org/W2440722156","https://openalex.org/W2565107431","https://openalex.org/W4232655934","https://openalex.org/W4241694836"],"related_works":["https://openalex.org/W2794850401","https://openalex.org/W2730312366","https://openalex.org/W2461483782","https://openalex.org/W868376623","https://openalex.org/W2150182456","https://openalex.org/W7130453252","https://openalex.org/W1982955412","https://openalex.org/W4404806394","https://openalex.org/W7155043584","https://openalex.org/W2522034994"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-07-22T00:00:00"}