{"id":"https://openalex.org/W2462736809","doi":null,"title":"Oleic acid uptake by jejunal and ileal rat brush border membrane vesicles.","display_name":"Oleic acid uptake by jejunal and ileal rat brush border membrane vesicles.","publication_year":1996,"publication_date":"1996-01-19","ids":{"openalex":"https://openalex.org/W2462736809","mag":"2462736809","pmid":"https://pubmed.ncbi.nlm.nih.gov/9386269"},"language":"en","primary_location":{"id":"pmid:9386269","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9386269","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of medical research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036137976","display_name":"Rafael Prieto","orcid":"https://orcid.org/0000-0001-8814-900X","observed_orcids":["https://orcid.org/0000-0001-8814-900X"]},"institutions":[{"id":"https://openalex.org/I50441567","display_name":"Universitat de les Illes Balears","ror":"https://ror.org/03e10x626","country_code":"ES","type":"education","lineage":["https://openalex.org/I50441567"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"R M Prieto","raw_affiliation_strings":["Department of Fundamental Biology and Health Sciences, Universitat de les Illes Balears, Cra. de Valldemossa, km. 7,5, Palma de Mallorca E-07071, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Fundamental Biology and Health Sciences, Universitat de les Illes Balears, Cra. de Valldemossa, km. 7,5, Palma de Mallorca E-07071, Spain","institution_ids":["https://openalex.org/I50441567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072719414","display_name":"Wolfgang Stremmel","orcid":"https://orcid.org/0000-0002-8545-1753","observed_orcids":["https://orcid.org/0000-0002-8545-1753"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W Stremmel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"C Sales","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Sales","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058664595","display_name":"J A Tur","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J A Tur","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.3675764,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"1","issue":"4","first_page":"199","last_page":"203"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.2498999983072281,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.2498999983072281,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.18629999458789825,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.11249999701976776,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brush-border-membrane-vesicles","display_name":"brush border membrane vesicles","score":0.8550000190734863},{"id":"https://openalex.org/keywords/jejunum","display_name":"jejunum","score":0.859000027179718},{"id":"https://openalex.org/keywords/ileum","display_name":"ileum","score":1.0},{"id":"https://openalex.org/keywords/carrier-mediated-transport","display_name":"carrier-mediated transport","score":0.7059999704360962},{"id":"https://openalex.org/keywords/fat-absorption","display_name":"fat absorption","score":0.9200000166893005},{"id":"https://openalex.org/keywords/small-intestine","display_name":"small intestine","score":0.6169999837875366},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.3409999907016754}],"concepts":[{"id":"https://openalex.org/C2776366702","wikidata":"https://www.wikidata.org/wiki/Q185765","display_name":"Jejunum","level":2,"score":0.8821699619293213},{"id":"https://openalex.org/C2777226302","wikidata":"https://www.wikidata.org/wiki/Q233345","display_name":"Ileum","level":2,"score":0.8335729837417603},{"id":"https://openalex.org/C5426402","wikidata":"https://www.wikidata.org/wiki/Q2462753","display_name":"Brush border","level":4,"score":0.7933305501937866},{"id":"https://openalex.org/C2781403372","wikidata":"https://www.wikidata.org/wiki/Q207688","display_name":"Oleic acid","level":2,"score":0.7684683799743652},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.652224063873291},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49822068214416504},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4548828899860382},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.44731175899505615},{"id":"https://openalex.org/C2777882243","wikidata":"https://www.wikidata.org/wiki/Q11090","display_name":"Small intestine","level":2,"score":0.4283936023712158},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.35608622431755066},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34858083724975586},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32371658086776733},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10369858145713806}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003594","descriptor_name":"Cytoplasmic Granules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007082","descriptor_name":"Ileum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007082","descriptor_name":"Ileum","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D007583","descriptor_name":"Jejunum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007583","descriptor_name":"Jejunum","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008871","descriptor_name":"Microvilli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019301","descriptor_name":"Oleic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:9386269","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9386269","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of medical research","raw_type":"Journal Article"},{"id":"mag:2462736809","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9386269","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2416776276","https://openalex.org/W2044642802","https://openalex.org/W2031464857","https://openalex.org/W2887849734","https://openalex.org/W2068177417","https://openalex.org/W1990711113","https://openalex.org/W1895895933","https://openalex.org/W2035158136","https://openalex.org/W2083717074","https://openalex.org/W2550347995"],"abstract_inverted_index":{"In":[0],"previous":[1],"works,":[2],"a":[3,32,46,137,150,159],"membrane":[4,15,66],"fatty":[5,49],"acid":[6,133],"transport":[7,139,163],"system":[8],"has":[9,60],"been":[10,61],"identified":[11],"in":[12,24,53,75,141,166],"brush":[13,64],"border":[14,65],"vesicles,":[16],"but":[17],"no":[18],"different":[19],"intestinal":[20],"regions":[21],"were":[22],"considered":[23],"these":[25],"studies.":[26],"To":[27],"test":[28],"the":[29,39,76,129,147],"existence":[30,148],"of":[31,35,45,58,72,149,162],"proximal-to-distal":[33,151],"gradient":[34,152],"fat":[36,154],"absorption":[37,155],"along":[38],"small":[40],"intestine,":[41],"transmembrane":[42],"influx":[43],"kinetics":[44,86],"representative":[47],"long-chain":[48],"acid,":[50,52],"3H-oleic":[51],"both":[54,78,142],"jejunum":[55,143],"and":[56,80,97,106,117,144],"ileum":[57,167],"rat":[59],"studied":[62],"using":[63],"vesicles":[67],"(BBMV).":[68],"With":[69],"increasing":[70],"concentration":[71],"unbound":[73],"oleate":[74],"medium,":[77],"jejunal":[79],"ileal":[81],"BBMV":[82],"showed":[83],"saturable":[84],"uptake":[85,134],"(Vmax":[87],"=":[88,99,108,119],"0.15":[89],"+/-":[90,101,110,121],"0.01":[91],"nmol.mg":[92,112],"protein-1":[93,113],"x":[94,114],"5":[95,115],"min-1":[96],"Km":[98,118],"136":[100],"29.1":[102],"nmol":[103,123],"for":[104,124,153],"jejunum,":[105],"Vmax":[107],"0.23":[109],"0.03":[111],"min1":[116],"196":[120],"50.3":[122],"ileum).":[125],"These":[126],"results":[127],"support":[128],"hypothesis":[130],"that":[131],"oleic":[132],"occurs":[135],"via":[136],"carrier-mediated":[138],"mechanism":[140],"ileum.":[145],"Furthermore,":[146],"was":[156],"apparent":[157],"with":[158],"higher":[160],"density":[161],"units":[164],"(Vmax)":[165],"compared":[168],"to":[169],"jejunum.":[170]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-07-22T00:00:00"}