{"id":"https://openalex.org/W2462433763","doi":null,"title":"Seroepidemiologic study of human coronavirus OC43 infections in Italy.","display_name":"Seroepidemiologic study of human coronavirus OC43 infections in Italy.","publication_year":1978,"publication_date":"1978-09-30","ids":{"openalex":"https://openalex.org/W2462433763","mag":"2462433763","pmid":"https://pubmed.ncbi.nlm.nih.gov/216378"},"language":"en","primary_location":{"id":"pmid:216378","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/216378","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bollettino dell'Istituto sieroterapico milanese","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069668709","display_name":"Giuseppe Gerna","orcid":"https://orcid.org/0000-0001-5956-2786","observed_orcids":["https://orcid.org/0000-0001-5956-2786"]},"institutions":[{"id":"https://openalex.org/I4210151645","display_name":"Policlinico San Matteo Fondazione","ror":"https://ror.org/05w1q1c88","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210151645","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Gerna","raw_affiliation_strings":["IRCCS Fondazione Policlinico San Matteo - Pavia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Fondazione Policlinico San Matteo - Pavia","institution_ids":["https://openalex.org/I4210151645"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111566811","display_name":"Ercole Cattaneo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Cattaneo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103647215","display_name":"P. M. Cereda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Cereda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5108436109","display_name":"Maria Grazia Revello","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151645","display_name":"Policlinico San Matteo Fondazione","ror":"https://ror.org/05w1q1c88","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210151645","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M G Revello","raw_affiliation_strings":["IRCCS Fondazione Policlinico San Matteo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Fondazione Policlinico San Matteo","institution_ids":["https://openalex.org/I4210151645"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.4929316,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"57","issue":"4","first_page":"535","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.5121999979019165,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.5121999979019165,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.21780000627040863,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.16750000417232513,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hcov-oc43","display_name":"HCoV-OC43","score":0.9959999918937683},{"id":"https://openalex.org/keywords/seroepidemiology","display_name":"seroepidemiology","score":0.9120000004768372},{"id":"https://openalex.org/keywords/seroprevalence","display_name":"seroprevalence","score":0.8529999852180481},{"id":"https://openalex.org/keywords/reinfection","display_name":"reinfection","score":0.9190000295639038},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.8399999737739563},{"id":"https://openalex.org/keywords/hemagglutination-inhibition-test","display_name":"hemagglutination inhibition test","score":0.9160000085830688},{"id":"https://openalex.org/keywords/complement-fixation-test","display_name":"complement fixation test","score":0.9800000190734863},{"id":"https://openalex.org/keywords/mouse-hepatitis-virus","display_name":"mouse hepatitis virus","score":0.3919999897480011},{"id":"https://openalex.org/keywords/northern-italy","display_name":"Northern Italy","score":0.6439999938011169}],"concepts":[{"id":"https://openalex.org/C152669594","wikidata":"https://www.wikidata.org/wiki/Q904197","display_name":"Complement fixation test","level":4,"score":0.8239274024963379},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7617663145065308},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7033254504203796},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6831367015838623},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.667061448097229},{"id":"https://openalex.org/C2779567548","wikidata":"https://www.wikidata.org/wiki/Q18907882","display_name":"Mouse hepatitis virus","level":5,"score":0.5723138451576233},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.536952018737793},{"id":"https://openalex.org/C2777648638","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus","level":5,"score":0.4711678922176361},{"id":"https://openalex.org/C2777410769","wikidata":"https://www.wikidata.org/wiki/Q2282887","display_name":"HBsAg","level":4,"score":0.45106226205825806},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4255833327770233},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.3822169005870819},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3650912046432495},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2901371419429779},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17083603143692017},{"id":"https://openalex.org/C2780593183","wikidata":"https://www.wikidata.org/wiki/Q6844","display_name":"Hepatitis B virus","level":3,"score":0.15988531708717346},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.08645063638687134},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003168","descriptor_name":"Complement Fixation Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003332","descriptor_name":"Coronaviridae","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003333","descriptor_name":"Coronaviridae Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003333","descriptor_name":"Coronaviridae Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D003333","descriptor_name":"Coronaviridae Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006385","descriptor_name":"Hemagglutination Inhibition Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012621","descriptor_name":"Seasons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014776","descriptor_name":"Virus Cultivation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:216378","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/216378","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bollettino dell'Istituto sieroterapico milanese","raw_type":"Journal Article"},{"id":"mag:2462433763","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/216378","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2088398949","https://openalex.org/W2131020673","https://openalex.org/W1964852361","https://openalex.org/W7098493283","https://openalex.org/W2336133541","https://openalex.org/W1492635936","https://openalex.org/W2070411318","https://openalex.org/W1514321728","https://openalex.org/W1984051965","https://openalex.org/W2164299265"],"abstract_inverted_index":{"Human":[0],"Coronavirus":[1],"OC43":[2,48,61,98,119],"from":[3,27,39,140],"suckling":[4],"mouse":[5,148,152],"brain":[6],"(SMB)":[7],"suspension":[8],"has":[9],"been":[10],"adapted":[11],"to":[12,76],"grow":[13],"in":[14,33,50,85,100,126],"human":[15],"embryonic":[16],"lung":[17],"fibroblast":[18],"cell":[19,29,141],"cultures.":[20],"Complement-fixing":[21],"and":[22,31,63,88,143],"hemagglutinating":[23],"antigens":[24,38],"were":[25],"prepared":[26,139],"infected":[28],"cultures":[30],"used":[32],"parallel":[34],"with":[35,130],"the":[36,45,57,72,77,122],"same":[37],"SMB":[40],"for":[41,56,82],"a":[42,68,94,115,127,134],"study":[43],"of":[44,47,59,71,90,97,118,137,146],"prevalence":[46,96],"antibody":[49,83,99,132],"Northern":[51,101],"Italy":[52],"as":[53,55,74,151],"well":[54],"serodiagnosis":[58,89],"recent":[60],"infections":[62],"reinfections.":[64],"Results":[65],"show":[66],"(i)":[67],"higher":[69],"sensitivity":[70],"hemagglutination-inhibition":[73],"compared":[75],"complement":[78],"fixation":[79],"test":[80],"both":[81],"detection":[84],"seroepidemiological":[86],"studies":[87],"acute":[91],"infections,":[92],"(ii)":[93],"high":[95,116],"Italy,":[102],"so":[103],"that":[104],"only":[105],"exceptionally":[106],"are":[107],"people":[108],"older":[109],"than":[110],"12":[111],"years":[112],"seronegative,":[113],"(iii)":[114],"rate":[117],"reinfections":[120],"during":[121],"winter-spring":[123],"season":[124],"1976/77":[125],"population":[128],"sample":[129],"preexisting":[131],"(iv)":[133],"good":[135],"quality":[136],"reagents":[138],"cultures,":[142],"hence":[144],"free":[145],"contaminating":[147],"viruses,":[149],"such":[150],"hepatitis":[153],"virus.":[154]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-07-22T00:00:00"}