{"id":"https://openalex.org/W2462394897","doi":null,"title":"Selective effect of cefoxitin prophylaxis on post-cesarean-section microbial flora.","display_name":"Selective effect of cefoxitin prophylaxis on post-cesarean-section microbial flora.","publication_year":1990,"publication_date":"1990-02-01","ids":{"openalex":"https://openalex.org/W2462394897","mag":"2462394897","pmid":"https://pubmed.ncbi.nlm.nih.gov/2406439"},"language":"en","primary_location":{"id":"pmid:2406439","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2406439","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of reproductive medicine","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109140658","display_name":"Mahmoud Ismail","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M A Ismail","raw_affiliation_strings":["Department of Medicine, University of Illinois College of Medicine, Chicago"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Illinois College of Medicine, Chicago","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":null,"display_name":"K E Nelson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K E Nelson","raw_affiliation_strings":["The University of Chicago,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Chicago,","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P Larson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P Larson","raw_affiliation_strings":["The University of Chicago,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Chicago,","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052357516","display_name":"Vijai K. Moses","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V K Moses","raw_affiliation_strings":["The University of Chicago,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Chicago,","institution_ids":["https://openalex.org/I40347166"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3882,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.84106376,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"35","issue":"2","first_page":"168","last_page":"74"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11080","display_name":"Surgical site infection prevention","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11080","display_name":"Surgical site infection prevention","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10453","display_name":"Maternal and Perinatal Health Interventions","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cefoxitin","display_name":"cefoxitin","score":1.0},{"id":"https://openalex.org/keywords/antibiotic-prophylaxis","display_name":"antibiotic prophylaxis","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cesarean-section","display_name":"cesarean section","score":0.9739999771118164},{"id":"https://openalex.org/keywords/postoperative-infection","display_name":"postoperative infection","score":0.9070000052452087},{"id":"https://openalex.org/keywords/anaerobic-bacteria","display_name":"anaerobic bacteria","score":0.9739999771118164},{"id":"https://openalex.org/keywords/enterococcus","display_name":"Enterococcus","score":0.9760000109672546},{"id":"https://openalex.org/keywords/bacteriuria","display_name":"bacteriuria","score":0.9179999828338623},{"id":"https://openalex.org/keywords/urinary-tract-infection","display_name":"urinary tract infection","score":0.9589999914169312},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"antibiotic resistance","score":0.6159999966621399},{"id":"https://openalex.org/keywords/superinfection","display_name":"superinfection","score":0.6759999990463257},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.5580000281333923}],"concepts":[{"id":"https://openalex.org/C2776124114","wikidata":"https://www.wikidata.org/wiki/Q2353907","display_name":"Cefoxitin","level":4,"score":0.9451370239257812},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8803082704544067},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.6459648609161377},{"id":"https://openalex.org/C2778602436","wikidata":"https://www.wikidata.org/wiki/Q4774943","display_name":"Antibiotic prophylaxis","level":3,"score":0.5490685701370239},{"id":"https://openalex.org/C2777831542","wikidata":"https://www.wikidata.org/wiki/Q537478","display_name":"Vaginal flora","level":3,"score":0.5392554998397827},{"id":"https://openalex.org/C2779617845","wikidata":"https://www.wikidata.org/wiki/Q1563808","display_name":"Superinfection","level":3,"score":0.47307926416397095},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.46840518712997437},{"id":"https://openalex.org/C2776216170","wikidata":"https://www.wikidata.org/wiki/Q632522","display_name":"Bacteriuria","level":3,"score":0.46578899025917053},{"id":"https://openalex.org/C2777234453","wikidata":"https://www.wikidata.org/wiki/Q2033092","display_name":"Flora (microbiology)","level":3,"score":0.46041184663772583},{"id":"https://openalex.org/C2780585763","wikidata":"https://www.wikidata.org/wiki/Q517258","display_name":"Enterococcus","level":3,"score":0.46007686853408813},{"id":"https://openalex.org/C2776688490","wikidata":"https://www.wikidata.org/wiki/Q1069606","display_name":"Chemoprophylaxis","level":2,"score":0.4568636119365692},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.43804463744163513},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.35479801893234253},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34705936908721924},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.32519862055778503},{"id":"https://openalex.org/C2777744392","wikidata":"https://www.wikidata.org/wiki/Q5880","display_name":"Vagina","level":2,"score":0.19163331389427185},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.13179820775985718},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0978347659111023},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09266746044158936},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002440","descriptor_name":"Cefoxitin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002584","descriptor_name":"Cervix Uteri","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002585","descriptor_name":"Cesarean Section","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004756","descriptor_name":"Enterobacteriaceae Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D004756","descriptor_name":"Enterobacteriaceae Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015163","descriptor_name":"Superinfection","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D015163","descriptor_name":"Superinfection","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2406439","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2406439","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of reproductive medicine","raw_type":"Clinical Trial"},{"id":"mag:2462394897","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2406439","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2065992437","https://openalex.org/W1933120338","https://openalex.org/W110966475","https://openalex.org/W2019112978","https://openalex.org/W2417008821","https://openalex.org/W1567075064","https://openalex.org/W2080752365","https://openalex.org/W2409301588","https://openalex.org/W1661739532","https://openalex.org/W2473879630"],"abstract_inverted_index":{"A":[0],"double-blind":[1],"study":[2],"was":[3,19,28,34,80],"done":[4],"to":[5,53,58,65,131],"test":[6],"the":[7,12,25,32,60,70,75,78,83,93,101,132,137,153,158],"efficacy":[8],"of":[9,14,74,85,96,125,144,155,157],"cefoxitin":[10],"in":[11,21,69,90,106],"prevention":[13],"post-cesarean-section":[15],"infection.":[16],"The":[17,142],"antibiotic":[18,79,165],"given":[20,29,40],"three":[22,110],"2-g":[23],"doses;":[24],"initial":[26],"dose":[27],"immediately":[30],"after":[31,140],"cord":[33],"clamped,":[35],"and":[36,42,63,109,147],"subsequent":[37],"doses":[38],"were":[39,88,134],"four":[41],"eight":[43],"hours":[44],"later.":[45],"Cefoxitin":[46],"prophylaxis":[47,166],"significantly":[48],"reduced":[49],"morbidity":[50],"serious":[51],"enough":[52],"require":[54],"therapeutic":[55],"antibiotics":[56],"or":[57],"prolong":[59],"hospital":[61],"stay":[62],"led":[64],"an":[66],"overall":[67],"reduction":[68,156],"anaerobic":[71],"microbial":[72],"flora":[73],"endocervix.":[76],"However,":[77],"selective":[81],"for":[82,167],"overgrowth":[84],"enterococci,":[86],"which":[87],"present":[89],"nearly":[91],"half":[92],"postoperative":[94],"cultures":[95],"patients":[97,112],"who":[98],"had":[99,113],"received":[100],"drug.":[102],"Enterococcal":[103],"sepsis":[104],"occurred":[105],"one":[107],"patient,":[108],"other":[111],"significant":[114],"bacteriuria":[115],"and/or":[116],"urinary":[117],"tract":[118],"infections":[119],"from":[120,136],"enterococci.":[121],"No":[122],"cefoxitin-resistant":[123],"strains":[124],"Enterobacteriaceae,":[126],"among":[127],"species":[128],"normally":[129],"sensitive":[130],"drug,":[133],"isolated":[135],"stool":[138],"samples":[139],"prophylaxis.":[141],"risk":[143,160],"enterococcal":[145],"colonization":[146],"superinfection":[148],"must":[149],"be":[150],"weighted":[151],"against":[152],"benefits":[154],"infection":[159],"when":[161],"deciding":[162],"upon":[163],"routine":[164],"cesarean":[168],"section.":[169]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-07-22T00:00:00"}