{"id":"https://openalex.org/W2460116951","doi":null,"title":"[Preliminary results of the 2nd multicenter study. Thrombocytapheresis with the Fresenius AS-104 blood cell separator and ring study of cell counting. Section of Therapeutic and Preparative Hemapheresis of the DGTI].","display_name":"[Preliminary results of the 2nd multicenter study. Thrombocytapheresis with the Fresenius AS-104 blood cell separator and ring study of cell counting. Section of Therapeutic and Preparative Hemapheresis of the DGTI].","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2460116951","mag":"2460116951","pmid":"https://pubmed.ncbi.nlm.nih.gov/7693271"},"language":"de","primary_location":{"id":"pmid:7693271","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7693271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beitrage zur Infusionstherapie = Contributions to infusion therapy","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108009774","display_name":"Norbert M\u00fcller","orcid":"https://orcid.org/0000-0001-6653-9103","observed_orcids":["https://orcid.org/0000-0001-6653-9103"]},"institutions":[{"id":"https://openalex.org/I4210119759","display_name":"Essen University Hospital","ror":"https://ror.org/02na8dn90","country_code":"DE","type":"funder","lineage":["https://openalex.org/I4210119759"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"N M\u00fcller","raw_affiliation_strings":["Institut f\u00fcr Transfusionsmedizin, Universit\u00e4tsklinikum Essen, BRD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Transfusionsmedizin, Universit\u00e4tsklinikum Essen, BRD","institution_ids":["https://openalex.org/I4210119759"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113758898","display_name":"V Kretschmer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Kretschmer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"H J Neumann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H J Neumann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5043556519","display_name":"T Weisswange","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Weisswange","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.33107896,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"31","issue":null,"first_page":"92","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.5957000255584717,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.5957000255584717,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.35519999265670776,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plateletpheresis","display_name":"plateletpheresis","score":0.8769999742507935},{"id":"https://openalex.org/keywords/thrombocytapheresis","display_name":"thrombocytapheresis","score":0.9240000247955322},{"id":"https://openalex.org/keywords/cell-separators","display_name":"cell separators","score":0.800000011920929},{"id":"https://openalex.org/keywords/multicenter-study","display_name":"multicenter study","score":0.734000027179718},{"id":"https://openalex.org/keywords/ring-study","display_name":"ring study","score":0.9409999847412109},{"id":"https://openalex.org/keywords/platelet-yield","display_name":"platelet yield","score":0.6769999861717224},{"id":"https://openalex.org/keywords/separation-efficiency","display_name":"separation efficiency","score":0.6439999938011169},{"id":"https://openalex.org/keywords/white-blood-cell-contamination","display_name":"white blood cell contamination","score":0.7570000290870667},{"id":"https://openalex.org/keywords/cell-counting","display_name":"cell counting","score":0.5130000114440918}],"concepts":[{"id":"https://openalex.org/C2779867487","wikidata":"https://www.wikidata.org/wiki/Q952508","display_name":"Plateletpheresis","level":4,"score":0.8738013505935669},{"id":"https://openalex.org/C185004128","wikidata":"https://www.wikidata.org/wiki/Q3011536","display_name":"Separator (oil production)","level":2,"score":0.6390673518180847},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.6358159780502319},{"id":"https://openalex.org/C2776738589","wikidata":"https://www.wikidata.org/wiki/Q618446","display_name":"Apheresis","level":3,"score":0.6069679260253906},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4032547175884247},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36271435022354126},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.22112411260604858},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.19602236151695251},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.17855224013328552},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12789905071258545},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001810","descriptor_name":"Blood Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002469","descriptor_name":"Cell Separation","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007958","descriptor_name":"Leukocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010976","descriptor_name":"Platelet Count","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D010983","descriptor_name":"Plateletpheresis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:7693271","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7693271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beitrage zur Infusionstherapie = Contributions to infusion therapy","raw_type":"English Abstract"},{"id":"mag:2460116951","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7693271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W32465906","https://openalex.org/W1993089213","https://openalex.org/W2419976729","https://openalex.org/W2799885860","https://openalex.org/W2082394946","https://openalex.org/W1964983076","https://openalex.org/W2471059472","https://openalex.org/W1973425275","https://openalex.org/W2050085883","https://openalex.org/W2014262689"],"abstract_inverted_index":{"Only":[0],"multicenter":[1,19],"studies":[2],"on":[3,91],"cell":[4,12,35,55,79],"separators":[5],"give":[6],"valid":[7],"data":[8,45],"to":[9,22],"compare":[10],"different":[11],"separators.":[13],"The":[14],"aim":[15],"of":[16,31,67,106,125,137],"the":[17,24,32,64,68,86,92,98,101,114,120,133],"2nd":[18],"study":[20,75],"was":[21],"evaluate":[23],"separation":[25,115],"protocol,":[26],"software":[27],"version":[28],"V":[29],"4.61,":[30],"Fresenius":[33],"AS-104":[34],"separator":[36],"for":[37,113],"efficiency":[38],"and":[39,54,60],"deviation":[40,118],"from":[41,46,100,119,132],"predicted":[42,121,134],"yields.":[43],"Plateletpheresis":[44],"twelve":[47],"hemapheresis":[48],"centers,":[49],"using":[50],"identical":[51],"apheresis":[52,87],"protocols":[53],"counting":[56,65],"methods,":[57],"were":[58,70,95],"registered":[59],"statistically":[61],"analyzed.":[62],"Additionally,":[63],"methods":[66],"centers":[69],"controlled":[71],"by":[72,97],"a":[73,84,140],"ring":[74,102],"with":[76],"biweekly":[77],"external":[78],"count":[80],"trials.":[81],"To":[82],"get":[83],"comparison,":[85],"data,":[88],"which":[89],"depend":[90],"center":[93],"effects,":[94],"corrected":[96],"values":[99],"study.":[103],"Preliminary":[104],"results":[105],"380":[107],"runs":[108,127],"are":[109],"45.2":[110],"+/-":[111],"8.1%":[112],"effectivity,":[116],"1.95%":[117],"yield,":[122],"whereby":[123],"90%":[124],"all":[126],"deviated":[128],"less":[129],"than":[130],"20%":[131],"yield.":[135],"50%":[136],"products":[138],"had":[139],"WBC":[141],"contamination":[142],"below":[143],"6":[144],"x":[145],"10(6).":[146]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-07-22T00:00:00"}