{"id":"https://openalex.org/W2434525932","doi":"https://doi.org/10.1182/blood.v93.9.3140.409a42_3140_3147","title":"Prevention of Transfusion-Associated Graft-Versus-Host Disease by Photochemical Treatment","display_name":"Prevention of Transfusion-Associated Graft-Versus-Host Disease by Photochemical Treatment","publication_year":1999,"publication_date":"1999-05-01","ids":{"openalex":"https://openalex.org/W2434525932","doi":"https://doi.org/10.1182/blood.v93.9.3140.409a42_3140_3147","mag":"2434525932","pmid":"https://pubmed.ncbi.nlm.nih.gov/10216113"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v93.9.3140.409a42_3140_3147","doi":"https://doi.org/10.1182/blood.v93.9.3140.409a42_3140_3147","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v93.9.3140.409a42_3140_3147","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026477342","display_name":"Joshua A. Grass","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154640","display_name":"Cerus (United States)","ror":"https://ror.org/04z9rrc30","country_code":"US","type":"company","lineage":["https://openalex.org/I4210154640"]},{"id":"https://openalex.org/I4390039285","display_name":"U-M Rogel Cancer Center","ror":"https://ror.org/05asdy483","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445","https://openalex.org/I4390039285"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua A. Grass","raw_affiliation_strings":["From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","From the Cerus Corporation Concord, CA","the University of Michigan Cancer Center Ann Arbor, MI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","institution_ids":["https://openalex.org/I4390039285"]},{"raw_affiliation_string":"From the Cerus Corporation Concord, CA","institution_ids":["https://openalex.org/I4210154640"]},{"raw_affiliation_string":"the University of Michigan Cancer Center Ann Arbor, MI","institution_ids":["https://openalex.org/I4390039285"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086449649","display_name":"Tamim Wafa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154640","display_name":"Cerus (United States)","ror":"https://ror.org/04z9rrc30","country_code":"US","type":"company","lineage":["https://openalex.org/I4210154640"]},{"id":"https://openalex.org/I4390039285","display_name":"U-M Rogel Cancer Center","ror":"https://ror.org/05asdy483","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445","https://openalex.org/I4390039285"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tamim Wafa","raw_affiliation_strings":["From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","From the Cerus Corporation Concord, CA","the University of Michigan Cancer Center Ann Arbor, MI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","institution_ids":["https://openalex.org/I4390039285"]},{"raw_affiliation_string":"From the Cerus Corporation Concord, CA","institution_ids":["https://openalex.org/I4210154640"]},{"raw_affiliation_string":"the University of Michigan Cancer Center Ann Arbor, MI","institution_ids":["https://openalex.org/I4390039285"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071019111","display_name":"Aaron Reames","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154640","display_name":"Cerus (United States)","ror":"https://ror.org/04z9rrc30","country_code":"US","type":"company","lineage":["https://openalex.org/I4210154640"]},{"id":"https://openalex.org/I4390039285","display_name":"U-M Rogel Cancer Center","ror":"https://ror.org/05asdy483","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445","https://openalex.org/I4390039285"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron Reames","raw_affiliation_strings":["From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","From the Cerus Corporation Concord, CA","the University of Michigan Cancer Center Ann Arbor, MI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","institution_ids":["https://openalex.org/I4390039285"]},{"raw_affiliation_string":"From the Cerus Corporation Concord, CA","institution_ids":["https://openalex.org/I4210154640"]},{"raw_affiliation_string":"the University of Michigan Cancer Center Ann Arbor, MI","institution_ids":["https://openalex.org/I4390039285"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076578124","display_name":"David S. Wages","orcid":"https://orcid.org/0000-0001-7407-6727","observed_orcids":["https://orcid.org/0000-0001-7407-6727"]},"institutions":[{"id":"https://openalex.org/I4210154640","display_name":"Cerus (United States)","ror":"https://ror.org/04z9rrc30","country_code":"US","type":"company","lineage":["https://openalex.org/I4210154640"]},{"id":"https://openalex.org/I4390039285","display_name":"U-M Rogel Cancer Center","ror":"https://ror.org/05asdy483","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445","https://openalex.org/I4390039285"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Wages","raw_affiliation_strings":["From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","From the Cerus Corporation Concord, CA","the University of Michigan Cancer Center Ann Arbor, MI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","institution_ids":["https://openalex.org/I4390039285"]},{"raw_affiliation_string":"From the Cerus Corporation Concord, CA","institution_ids":["https://openalex.org/I4210154640"]},{"raw_affiliation_string":"the University of Michigan Cancer Center Ann Arbor, MI","institution_ids":["https://openalex.org/I4390039285"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051775780","display_name":"Laurence Corash","orcid":"https://orcid.org/0000-0002-8615-9869","observed_orcids":["https://orcid.org/0000-0002-8615-9869"]},"institutions":[{"id":"https://openalex.org/I4210154640","display_name":"Cerus (United States)","ror":"https://ror.org/04z9rrc30","country_code":"US","type":"company","lineage":["https://openalex.org/I4210154640"]},{"id":"https://openalex.org/I4390039285","display_name":"U-M Rogel Cancer Center","ror":"https://ror.org/05asdy483","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445","https://openalex.org/I4390039285"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurence Corash","raw_affiliation_strings":["From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","From the Cerus Corporation Concord, CA","the University of Michigan Cancer Center Ann Arbor, MI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","institution_ids":["https://openalex.org/I4390039285"]},{"raw_affiliation_string":"From the Cerus Corporation Concord, CA","institution_ids":["https://openalex.org/I4210154640"]},{"raw_affiliation_string":"the University of Michigan Cancer Center Ann Arbor, MI","institution_ids":["https://openalex.org/I4390039285"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023099227","display_name":"James L.M. Ferrara","orcid":"https://orcid.org/0000-0001-8595-3940","observed_orcids":["https://orcid.org/0000-0001-8595-3940"]},"institutions":[{"id":"https://openalex.org/I4210154640","display_name":"Cerus (United States)","ror":"https://ror.org/04z9rrc30","country_code":"US","type":"company","lineage":["https://openalex.org/I4210154640"]},{"id":"https://openalex.org/I4390039285","display_name":"U-M Rogel Cancer Center","ror":"https://ror.org/05asdy483","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445","https://openalex.org/I4390039285"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James L.M. Ferrara","raw_affiliation_strings":["From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","From the Cerus Corporation Concord, CA","the University of Michigan Cancer Center Ann Arbor, MI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","institution_ids":["https://openalex.org/I4390039285"]},{"raw_affiliation_string":"From the Cerus Corporation Concord, CA","institution_ids":["https://openalex.org/I4210154640"]},{"raw_affiliation_string":"the University of Michigan Cancer Center Ann Arbor, MI","institution_ids":["https://openalex.org/I4390039285"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108356232","display_name":"Lily Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154640","display_name":"Cerus (United States)","ror":"https://ror.org/04z9rrc30","country_code":"US","type":"company","lineage":["https://openalex.org/I4210154640"]},{"id":"https://openalex.org/I4390039285","display_name":"U-M Rogel Cancer Center","ror":"https://ror.org/05asdy483","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445","https://openalex.org/I4390039285"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lily Lin","raw_affiliation_strings":["From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","From the Cerus Corporation Concord, CA","the University of Michigan Cancer Center Ann Arbor, MI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Cerus Corporation Concord, CA; the University of Michigan Cancer Center Ann Arbor, MI; and the Baxter Healthcare Corporation, Fenwal Division, Viral Inactivation, Round Lake, IL","institution_ids":["https://openalex.org/I4390039285"]},{"raw_affiliation_string":"From the Cerus Corporation Concord, CA","institution_ids":["https://openalex.org/I4210154640"]},{"raw_affiliation_string":"the University of Michigan Cancer Center Ann Arbor, MI","institution_ids":["https://openalex.org/I4390039285"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":5.1037,"has_fulltext":false,"cited_by_count":155,"citation_normalized_percentile":{"value":0.96161855,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"93","issue":"9","first_page":"3140","last_page":"3147"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.5853999853134155,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.5853999853134155,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.39089998602867126,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transfusion-associated-graft-versus-host-disease","display_name":"transfusion-associated graft-versus-host disease","score":0.9419999718666077},{"id":"https://openalex.org/keywords/photochemical-treatment","display_name":"photochemical treatment","score":0.9390000104904175},{"id":"https://openalex.org/keywords/uva-irradiation","display_name":"UVA irradiation","score":0.8330000042915344},{"id":"https://openalex.org/keywords/platelet-concentrates","display_name":"platelet concentrates","score":0.7590000033378601},{"id":"https://openalex.org/keywords/gamma-irradiation","display_name":"gamma irradiation","score":0.7630000114440918},{"id":"https://openalex.org/keywords/t-cell-inactivation","display_name":"T cell inactivation","score":0.7770000100135803},{"id":"https://openalex.org/keywords/thymic-hypoplasia","display_name":"thymic hypoplasia","score":0.8050000071525574},{"id":"https://openalex.org/keywords/pancytopenia","display_name":"pancytopenia","score":0.7239999771118164},{"id":"https://openalex.org/keywords/splenomegaly","display_name":"splenomegaly","score":0.8769999742507935}],"concepts":[{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.776272177696228},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.669886589050293},{"id":"https://openalex.org/C2779382419","wikidata":"https://www.wikidata.org/wiki/Q1757427","display_name":"Pancytopenia","level":3,"score":0.6330957412719727},{"id":"https://openalex.org/C2779972918","wikidata":"https://www.wikidata.org/wiki/Q1194520","display_name":"Graft-versus-host disease","level":3,"score":0.5831477046012878},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.576619029045105},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.5132830142974854},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.46781301498413086},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4136219620704651},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3410533666610718},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2175593376159668}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004906","descriptor_name":"Erythrocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005720","descriptor_name":"Gamma Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007958","descriptor_name":"Leukocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010778","descriptor_name":"Photochemotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011564","descriptor_name":"Furocoumarins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D014466","descriptor_name":"Ultraviolet Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017710","descriptor_name":"Lymphocyte Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1182/blood.v93.9.3140.409a42_3140_3147","doi":"https://doi.org/10.1182/blood.v93.9.3140.409a42_3140_3147","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v93.9.3140.409a42_3140_3147","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"doi:10.1182/blood.v93.9.3140","doi":"https://doi.org/10.1182/blood.v93.9.3140","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v93.9.3140","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmid:10216113","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10216113","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2289578583","display_name":"PARTNERS IN ASTHMA EDUCATION","funder_award_id":"K07HL003340","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5207524439","display_name":null,"funder_award_id":"HL 3340","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7172930911","display_name":null,"funder_award_id":"CA 34952","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W19838161","https://openalex.org/W207432979","https://openalex.org/W269416423","https://openalex.org/W1510827637","https://openalex.org/W1544331058","https://openalex.org/W1967935272","https://openalex.org/W1969658034","https://openalex.org/W1980605805","https://openalex.org/W1981302144","https://openalex.org/W2002237213","https://openalex.org/W2041147614","https://openalex.org/W2114599943","https://openalex.org/W2137165273","https://openalex.org/W2145812705","https://openalex.org/W2334062077","https://openalex.org/W2413780691","https://openalex.org/W2418447058","https://openalex.org/W2462660974","https://openalex.org/W3147784190","https://openalex.org/W6715907728"],"related_works":["https://openalex.org/W2249632132","https://openalex.org/W1998256984","https://openalex.org/W2100788438","https://openalex.org/W2980037475","https://openalex.org/W2750464378","https://openalex.org/W2325471533","https://openalex.org/W2151624673","https://openalex.org/W2171745843","https://openalex.org/W4220725324","https://openalex.org/W2795369545"],"abstract_inverted_index":{"Photochemical":[0],"treatment":[1,55],"(PCT)":[2],"with":[3,59,104,199,211,215],"the":[4,30,121,171,183],"psoralen":[5],"S-59":[6,107,223],"and":[7,20,94,108,114,159,167,176,188,204,224,230,263],"long":[8],"wavelength":[9],"ultraviolet":[10],"light":[11],"(UVA)":[12],"inactivates":[13],"high":[14,258],"titers":[15],"of":[16,32,123,149,162,178,191,260,281],"contaminating":[17],"viruses,":[18],"bacteria,":[19],"leukocytes":[21,102,213],"in":[22,40,53,125,170,182,238,254,265],"human":[23],"platelet":[24],"concentrates.":[25],"The":[26],"present":[27],"study":[28],"evaluated":[29],"efficacy":[31],"PCT":[33,96,271],"to":[34,46,119,256,276],"prevent":[35],"transfusion-associated":[36],"graft-versus-host":[37],"disease":[38],"(TA-GVHD)":[39],"vivo":[41],"using":[42],"a":[43,129],"well-characterized":[44],"parent":[45],"F1":[47],"murine":[48,246],"transfusion":[49],"model.":[50],"Recipient":[51],"mice":[52,66,75,85,98,127,209],"four":[54],"groups":[56],"were":[57,117,249],"transfused":[58,210],"10(8)":[60],"splenic":[61,69,79,92,101,212],"leukocytes.":[62],"(1)":[63],"Control":[64],"group":[65,74,84,97,173,185],"received":[67,76,86,99],"syngeneic":[68],"leukocyte":[70],"transfusions;":[71],"(2)":[72],"GVHD":[73,184],"untreated":[77],"allogeneic":[78,91,100],"leukocytes;":[80,93],"(3)":[81],"gamma":[82,87,218,277],"radiation":[83,219],"irradiated":[88],"(2,500":[89,216],"cGy)":[90,217],"(4)":[95],"treated":[103,214],"150":[105,221],"micromol/L":[106,222],"2.1":[109,225],"J/cm2":[110,226],"UVA.":[111],"Multiple":[112],"biological":[113],"clinical":[115,147,187],"parameters":[116],"used":[118],"monitor":[120],"development":[122],"TA-GVHD":[124,150],"recipient":[126],"over":[128],"10-week":[130],"posttransfusion":[131],"observation":[132],"period:":[133],"peripheral":[134],"blood":[135],"cell":[136],"levels,":[137],"spleen":[138],"size,":[139],"engraftment":[140,198],"by":[141,251],"donor":[142,200],"T":[143,202,247],"cells,":[144,203],"thymic":[145,205],"cellularity,":[146],"signs":[148],"(weight":[151],"loss,":[152],"activity,":[153],"posture,":[154],"fur":[155],"texture,":[156],"skin":[157],"integrity),":[158],"histologic":[160],"lesions":[161,190],"liver,":[163],"spleen,":[164],"bone":[165],"marrow,":[166],"skin.":[168],"Mice":[169,181],"control":[172],"remained":[174,228],"healthy":[175,229],"free":[177],"detectable":[179,234],"disease.":[180],"developed":[186],"histological":[189],"TA-GVHD,":[192],"including":[193],"pancytopenia,":[194],"marked":[195],"splenomegaly,":[196],"wasting,":[197],"derived":[201],"hypoplasia.":[206],"In":[207],"contrast,":[208],"or":[220],"UVA":[227],"did":[231],"not":[232],"develop":[233],"TA-GVHD.":[235,282],"Using":[236],"an":[237,273],"vitro":[239],"T-cell":[240],"proliferation":[241],"assay,":[242],"greater":[243],"than":[244],"10(5.1)":[245],"cells":[248],"inactivated":[250],"PCT.":[252],"Therefore,":[253],"addition":[255],"inactivating":[257],"levels":[259],"pathogenic":[261],"viruses":[262],"bacteria":[264],"PC,":[266],"these":[267],"data":[268],"indicate":[269],"that":[270],"is":[272],"effective":[274],"alternative":[275],"irradiation":[278],"for":[279],"prevention":[280]},"counts_by_year":[{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}