{"id":"https://openalex.org/W2432939862","doi":null,"title":"Age dependent changes in mitochondrial FoF1 ATP synthase in regenerating rat-liver.","display_name":"Age dependent changes in mitochondrial FoF1 ATP synthase in regenerating rat-liver.","publication_year":1994,"publication_date":"1994-05-01","ids":{"openalex":"https://openalex.org/W2432939862","mag":"2432939862","pmid":"https://pubmed.ncbi.nlm.nih.gov/8081201"},"language":"en","primary_location":{"id":"pmid:8081201","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8081201","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry and molecular biology international","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008985346","display_name":"Ferruccio GUERRIERI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F Guerrieri","raw_affiliation_strings":["Institute of Medical Biochemistry and Chemistry, University of Bari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biochemistry and Chemistry, University of Bari, Italy","institution_ids":["https://openalex.org/I5561750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027211419","display_name":"Martin Kalous","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Kalous","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110163208","display_name":"G. Capozza","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Capozza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054725924","display_name":"Leonilde Muolo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Muolo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055590460","display_name":"Z Drahota","orcid":"https://orcid.org/0000-0003-2117-6809","observed_orcids":["https://orcid.org/0000-0003-2117-6809"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Z Drahota","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"S Papa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Papa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.637,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.64407592,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":92},"biblio":{"volume":"33","issue":"1","first_page":"117","last_page":"29"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.010400000028312206,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/f0f1-atp-synthase","display_name":"F0F1-ATP synthase","score":0.9390000104904175},{"id":"https://openalex.org/keywords/liver-regeneration","display_name":"liver regeneration","score":0.8980000019073486},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.8119999766349792},{"id":"https://openalex.org/keywords/partial-hepatectomy","display_name":"partial hepatectomy","score":0.9279999732971191},{"id":"https://openalex.org/keywords/mitochondrial-atpase-activity","display_name":"mitochondrial ATPase activity","score":0.5789999961853027},{"id":"https://openalex.org/keywords/respiratory-control-index","display_name":"respiratory control index","score":0.7870000004768372},{"id":"https://openalex.org/keywords/submitochondrial-particles","display_name":"submitochondrial particles","score":0.8320000171661377},{"id":"https://openalex.org/keywords/age-related-changes","display_name":"age-related changes","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C60538801","wikidata":"https://www.wikidata.org/wiki/Q7631706","display_name":"Submitochondrial particle","level":3,"score":0.9552799463272095},{"id":"https://openalex.org/C112243037","wikidata":"https://www.wikidata.org/wiki/Q22327117","display_name":"ATP synthase","level":3,"score":0.8333120346069336},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.6853358745574951},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.47797176241874695},{"id":"https://openalex.org/C2776795407","wikidata":"https://www.wikidata.org/wiki/Q19597761","display_name":"Liver regeneration","level":3,"score":0.4575670063495636},{"id":"https://openalex.org/C75385678","wikidata":"https://www.wikidata.org/wiki/Q4896390","display_name":"Inner mitochondrial membrane","level":3,"score":0.44175297021865845},{"id":"https://openalex.org/C100206155","wikidata":"https://www.wikidata.org/wiki/Q570714","display_name":"Bioenergetics","level":3,"score":0.4346825182437897},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4275129437446594},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42617303133010864},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41502249240875244},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40031176805496216},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.3690381348133087}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006180","descriptor_name":"Proton-Translocating ATPases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006498","descriptor_name":"Hepatectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008930","descriptor_name":"Mitochondria, Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8081201","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8081201","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry and molecular biology international","raw_type":"Comparative Study"},{"id":"mag:2432939862","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8081201","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W17634757","https://openalex.org/W2098490878","https://openalex.org/W35445048","https://openalex.org/W2016041548","https://openalex.org/W2082404317","https://openalex.org/W263615600","https://openalex.org/W2413540174","https://openalex.org/W1971773954","https://openalex.org/W1964133951","https://openalex.org/W2408495683"],"abstract_inverted_index":{"The":[0],"effect":[1],"of":[2,14,55,60,75,77,87,129,145,147,157],"aging":[3],"on":[4,9],"rat":[5],"liver":[6,16,33,88,135],"regeneration":[7,136],"and":[8,114,152],"the":[10,37,42,57,68,73,99,109,115,123,126,130,143,149,153,158],"FoF1-ATP":[11,131],"synthase":[12,132],"complex":[13],"isolated":[15],"mitochondria":[17,63],"was":[18,34,45,50,101,112],"followed":[19,102],"after":[20],"partial":[21],"(70%)":[22],"hepatectomy.":[23],"ATP":[24,78],"hydrolase":[25],"activity":[26,44],"in":[27,64,79,98,107,125,142],"submitochondrial":[28,82],"particles":[29],"prepared":[30],"from":[31],"regenerating":[32],"first":[35,85],"depressed;":[36],"time":[38],"needed":[39],"to":[40],"reach":[41],"lowest":[43],"age":[46],"dependent.":[47],"This":[48,84],"decrease":[49,54],"accompanied":[51,138],"by":[52,94,103,139],"parallel":[53,140],"i)":[56],"respiratory":[58,69],"rate":[59,74],"succinate":[61,80],"supplemented":[62,81],"state":[65],"III;":[66],"ii)":[67],"control":[70],"index;":[71],"iii)":[72],"synthesis":[76],"particles.":[83],"phase":[86,97,106],"regeneration,":[89],"characterized":[90],"at":[91],"all":[92],"ages":[93],"a":[95,104],"lag":[96],"growth,":[100],"second":[105],"which":[108],"tissue":[110],"mass":[111],"restored":[113],"enzyme":[116],"activities":[117,128],"normalized.":[118],"Immunoblot":[119],"analysis":[120],"showed":[121],"that":[122],"changes":[124,141],"catalytic":[127,150],"observed":[133],"during":[134],"were":[137],"amount":[144],"subunits":[146],"both":[148],"(F1)":[151],"membrane":[154],"(Fo)":[155],"sector":[156],"complex.":[159]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}