{"id":"https://openalex.org/W2432230000","doi":null,"title":"Managing long-term therapy for panic disorder.","display_name":"Managing long-term therapy for panic disorder.","publication_year":1990,"publication_date":"1990-11-01","ids":{"openalex":"https://openalex.org/W2432230000","mag":"2432230000","pmid":"https://pubmed.ncbi.nlm.nih.gov/2228994"},"language":"en","primary_location":{"id":"pmid:2228994","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2228994","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112010237","display_name":"G. D. Burrows","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I2800453128","display_name":"Austin Hospital","ror":"https://ror.org/010mv7n52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800453128","https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"G D Burrows","raw_affiliation_strings":["Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I2800453128"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112010237"],"corresponding_institution_ids":["https://openalex.org/I165779595","https://openalex.org/I2800453128"],"apc_list":null,"apc_paid":null,"fwci":1.1009,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.81202312,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"51 Suppl","issue":null,"first_page":"9","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13118","display_name":"Psychological Treatments and Disorders","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/panic-disorder","display_name":"panic disorder","score":1.0},{"id":"https://openalex.org/keywords/long-term-treatment","display_name":"long-term treatment","score":0.8880000114440918},{"id":"https://openalex.org/keywords/benzodiazepines","display_name":"benzodiazepines","score":0.8939999938011169},{"id":"https://openalex.org/keywords/alprazolam","display_name":"alprazolam","score":0.9829999804496765},{"id":"https://openalex.org/keywords/tricyclic-antidepressants","display_name":"tricyclic antidepressants","score":0.953000009059906},{"id":"https://openalex.org/keywords/monoamine-oxidase-inhibitors","display_name":"monoamine oxidase inhibitors","score":0.9980000257492065},{"id":"https://openalex.org/keywords/combined-pharmacotherapy-and-psychotherapy","display_name":"combined psychotherapy and pharmacotherapy","score":0.9290000200271606},{"id":"https://openalex.org/keywords/medication-tapering","display_name":"medication tapering","score":0.9129999876022339},{"id":"https://openalex.org/keywords/treatment-duration","display_name":"treatment duration","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C2777196872","wikidata":"https://www.wikidata.org/wiki/Q319877","display_name":"Alprazolam","level":3,"score":0.8474228382110596},{"id":"https://openalex.org/C2781081902","wikidata":"https://www.wikidata.org/wiki/Q3539074","display_name":"Tricyclic","level":2,"score":0.7973335981369019},{"id":"https://openalex.org/C2777529043","wikidata":"https://www.wikidata.org/wiki/Q741713","display_name":"Panic disorder","level":3,"score":0.7376283407211304},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.715367317199707},{"id":"https://openalex.org/C2781073023","wikidata":"https://www.wikidata.org/wiki/Q1747559","display_name":"Phenelzine","level":4,"score":0.6175594925880432},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.540785551071167},{"id":"https://openalex.org/C2780712732","wikidata":"https://www.wikidata.org/wiki/Q208450","display_name":"Panic","level":3,"score":0.5253219604492188},{"id":"https://openalex.org/C2778173252","wikidata":"https://www.wikidata.org/wiki/Q83871","display_name":"Benzodiazepine","level":3,"score":0.5056579113006592},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.4959460198879242},{"id":"https://openalex.org/C2776024655","wikidata":"https://www.wikidata.org/wiki/Q410867","display_name":"Monoamine oxidase","level":3,"score":0.4860427975654602},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2742310166358948},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.2629050612449646},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22796562314033508},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000525","descriptor_name":"Alprazolam","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000929","descriptor_name":"Antidepressive Agents, Tricyclic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001569","descriptor_name":"Benzodiazepines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008996","descriptor_name":"Monoamine Oxidase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D010200","descriptor_name":"Panic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011613","descriptor_name":"Psychotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2228994","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2228994","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Journal Article"},{"id":"mag:2432230000","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2228994","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2009773419","https://openalex.org/W2068746830","https://openalex.org/W2052148871","https://openalex.org/W2418617480","https://openalex.org/W1890259382","https://openalex.org/W2406451703","https://openalex.org/W6983185748","https://openalex.org/W2026437336","https://openalex.org/W2029285692","https://openalex.org/W2000679042"],"abstract_inverted_index":{"Diagnostic":[0],"criteria":[1],"for":[2,23,73],"panic":[3],"disorder":[4],"have":[5,35],"been":[6,36],"well":[7],"defined;":[8],"but":[9],"treatment":[10,22],"modalities,":[11],"less":[12],"so.":[13],"Combined":[14],"psychotherapy":[15],"and":[16,32],"pharmacotherapy":[17],"is":[18,71],"the":[19,47,69],"most":[20],"effective":[21,38,54],"these":[24],"disorders.":[25],"Benzodiazepines,":[26],"tricyclic":[27],"antidepressants,":[28],"monoamine":[29],"oxidase":[30],"inhibitors,":[31],"other":[33],"medications":[34],"found":[37],"in":[39,55],"clinical":[40],"studies.":[41],"Alprazolam,":[42],"a":[43,56,83],"triazolo":[44],"analog":[45],"of":[46],"1,4":[48],"benzodiazepine":[49],"class,":[50],"recently":[51],"was":[52],"proved":[53],"cross-national":[57],"study":[58],"involving":[59],"approximately":[60],"1700":[61],"patients,":[62],"with":[63,68],"minimal":[64],"side":[65],"effects.":[66],"Therapy":[67],"medication":[70],"advised":[72],"at":[74,86],"least":[75,87],"6":[76],"months.":[77],"Medications":[78],"should":[79],"be":[80],"tapered":[81],"over":[82],"prolonged":[84],"period,":[85],"8":[88],"weeks,":[89],"especially":[90],"where":[91],"high":[92],"doses":[93],"are":[94],"employed.":[95]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}