{"id":"https://openalex.org/W2432007971","doi":null,"title":"Long-term comparative mortality in hyperthyroid patients treated with radio-iodine, a cohort study in England.","display_name":"Long-term comparative mortality in hyperthyroid patients treated with radio-iodine, a cohort study in England.","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W2432007971","mag":"2432007971","pmid":"https://pubmed.ncbi.nlm.nih.gov/11510510"},"language":"en","primary_location":{"id":"pmid:11510510","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11510510","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of insurance medicine (New York, N.Y.)","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011392053","display_name":"Richard B Singer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"R B Singer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5011392053"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.31836096,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"33","issue":"2","first_page":"133","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.006599999964237213,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperthyroidism","display_name":"hyperthyroidism","score":0.9890000224113464},{"id":"https://openalex.org/keywords/radioactive-iodine-therapy","display_name":"radioiodine therapy","score":0.9369999766349792},{"id":"https://openalex.org/keywords/iodine-131","display_name":"iodine-131","score":0.9940000176429749},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.9229999780654907},{"id":"https://openalex.org/keywords/standardized-mortality-ratio","display_name":"standardized mortality ratio","score":0.8700000047683716},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.921999990940094},{"id":"https://openalex.org/keywords/cerebrovascular-mortality","display_name":"cerebrovascular disease mortality","score":0.9940000176429749},{"id":"https://openalex.org/keywords/fracture-mortality","display_name":"fracture mortality","score":0.9789999723434448},{"id":"https://openalex.org/keywords/cancer-mortality","display_name":"cancer mortality","score":0.8809999823570251},{"id":"https://openalex.org/keywords/long-term-follow-up","display_name":"long-term follow-up","score":0.6600000262260437},{"id":"https://openalex.org/keywords/radiation-exposure","display_name":"radiation exposure","score":0.3140000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8630865812301636},{"id":"https://openalex.org/C102803821","wikidata":"https://www.wikidata.org/wiki/Q7598403","display_name":"Standardized mortality ratio","level":3,"score":0.6125127077102661},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5419501066207886},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.5384440422058105},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.4919871985912323},{"id":"https://openalex.org/C3018792137","wikidata":"https://www.wikidata.org/wiki/Q6914399","display_name":"Excess mortality","level":3,"score":0.4532226324081421},{"id":"https://openalex.org/C29374701","wikidata":"https://www.wikidata.org/wiki/Q1931388","display_name":"Cause of death","level":3,"score":0.4454440176486969},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.43281054496765137},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.42652150988578796},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3910977244377136},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3435094952583313},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28568151593208313},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1534695029258728},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004307","descriptor_name":"Dose-Response Relationship, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004739","descriptor_name":"England","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006980","descriptor_name":"Hyperthyroidism","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D006980","descriptor_name":"Hyperthyroidism","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013222","descriptor_name":"State Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:11510510","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11510510","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of insurance medicine (New York, N.Y.)","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.455.7458","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.455.7458","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://aaimedicine.org/journal-of-insurance-medicine/jim/2001/033-02-0133.pdf","raw_type":"text"},{"id":"mag:2432007971","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11510510","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2060905795"],"related_works":["https://openalex.org/W7100854916","https://openalex.org/W2060905795","https://openalex.org/W168270653","https://openalex.org/W2090770715","https://openalex.org/W1968700299","https://openalex.org/W2101280599","https://openalex.org/W2133378341","https://openalex.org/W2338086962","https://openalex.org/W2036814915","https://openalex.org/W2138054446"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,29],"focus":[2],"of":[3,40,51,93,104,115,138],"this":[4],"long-term":[5],"study":[6,30],"(entry":[7],"1950-1989,":[8],"follow-up":[9],"to":[10,86],"1996)":[11],"on":[12,19,34],"hyperthyroid":[13],"patients":[14,36],"treated":[15],"with":[16,59,97,135],"131I":[17],"was":[18,31,128,154,166],"all-cause":[20,132],"mortality":[21,84,127,133,153],"and":[22,77,80,100,141,145,148,162],"some":[23],"specific":[24],"causes":[25,92],"other":[26],"than":[27],"cancer.":[28],"carried":[32],"out":[33],"7209":[35],"who":[37],"were":[38,56,73,108],"residents":[39],"the":[41,67,112,119,157],"Midlands":[42],"area":[43],"around":[44],"Birmingham,":[45],"England.":[46],"In":[47],"a":[48],"total":[49],"exposure":[50],"105,028":[52],"patient-years,":[53],"3611":[54],"deaths":[55,61,149],"observed,":[57],"compared":[58],"3186":[60],"expected":[62,78],"from":[63,150],"age/sex-matched":[64],"rates":[65],"in":[66,95,156,170],"English":[68],"life":[69],"tables.":[70],"RESULTS:":[71],"Data":[72],"reported":[74,168],"for":[75,111,118,131,143],"observed":[76],"deaths,":[79,147],"SMR":[81,137],"values":[82],"(standardized":[83],"ratios":[85],"one":[87],"decimal":[88],"place)":[89],"by":[90,121],"selected":[91],"death":[94],"combinations":[96],"duration,":[98],"age,":[99],"3":[101],"dosage":[102,113],"groups":[103,114],"131I.":[105],"Exposure":[106],"data":[107],"given":[109],"only":[110,139],"131I,":[116],"not":[117],"results":[120],"age":[122],"or":[123],"duration.":[124],"CONCLUSIONS:":[125],"Comparative":[126],"significantly":[129],"increased":[130],"(but":[134],"an":[136],"1.13),":[140],"also":[142],"cardiovascular":[144],"cerebrovascular":[146],"fracture.":[151],"Excess":[152],"greatest":[155],"first":[158],"year":[159],"after":[160],"entry,":[161],"decreased":[163],"thereafter.":[164],"There":[165],"no":[167],"increase":[169],"cancer":[171],"mortality.":[172]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}