{"id":"https://openalex.org/W2431326093","doi":null,"title":"Nocturnal mechanical ventilation improves exercise capacity in kyphoscoliotic patients with respiratory impairment.","display_name":"Nocturnal mechanical ventilation improves exercise capacity in kyphoscoliotic patients with respiratory impairment.","publication_year":2003,"publication_date":"2003-10-01","ids":{"openalex":"https://openalex.org/W2431326093","mag":"2431326093","pmid":"https://pubmed.ncbi.nlm.nih.gov/15148837"},"language":"en","primary_location":{"id":"pmid:15148837","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15148837","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","raw_type":"Comment"},"volume":null,"type":"letter","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079012152","display_name":"Salvatore Fuschillo","orcid":"https://orcid.org/0000-0002-1393-4473","observed_orcids":["https://orcid.org/0000-0002-1393-4473"]},"institutions":[{"id":"https://openalex.org/I4210105320","display_name":"Fondazione Salvatore Maugeri","ror":"https://ror.org/01e8tvg28","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210105320","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S Fuschillo","raw_affiliation_strings":["Division of Pneumology, Salvatore Maugeri Foundation IRCCS, Scientific Institute of Telese Terme (BN), Via Bagni Vecchi 1, 82037 Telese Terme, BN, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pneumology, Salvatore Maugeri Foundation IRCCS, Scientific Institute of Telese Terme (BN), Via Bagni Vecchi 1, 82037 Telese Terme, BN, Italy","institution_ids":["https://openalex.org/I4210105320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004030902","display_name":"Alberto De Felice","orcid":"https://orcid.org/0000-0003-1673-0780","observed_orcids":["https://orcid.org/0000-0003-1673-0780"]},"institutions":[{"id":"https://openalex.org/I4210091499","display_name":"Istituti Clinici Scientifici Maugeri","ror":"https://ror.org/00mc77d93","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210091499","https://openalex.org/I4210105320","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A De Felice","raw_affiliation_strings":["Istituti Clinici Scientifici Maugeri Spa \u2013 Societ\u00e0 Benefit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituti Clinici Scientifici Maugeri Spa \u2013 Societ\u00e0 Benefit","institution_ids":["https://openalex.org/I4210091499"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077500733","display_name":"Carlo Gaudiosi","orcid":"https://orcid.org/0000-0002-8724-9719","observed_orcids":["https://orcid.org/0000-0002-8724-9719"]},"institutions":[{"id":"https://openalex.org/I4210105320","display_name":"Fondazione Salvatore Maugeri","ror":"https://ror.org/01e8tvg28","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210105320","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"C Gaudiosi","raw_affiliation_strings":["Fondazione Salvatore Maugeri, Pavia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Salvatore Maugeri, Pavia","institution_ids":["https://openalex.org/I4210105320"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110308836","display_name":"Gianni Balzano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091499","display_name":"Istituti Clinici Scientifici Maugeri","ror":"https://ror.org/00mc77d93","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210091499","https://openalex.org/I4210105320","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Balzano","raw_affiliation_strings":["Istituti Clinici Scientifici Maugeri Spa \u2013 Societ\u00e0 Benefit"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituti Clinici Scientifici Maugeri Spa \u2013 Societ\u00e0 Benefit","institution_ids":["https://openalex.org/I4210091499"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"59","issue":"4","first_page":"281","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.7699999809265137,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.7699999809265137,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.12729999423027039,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11030","display_name":"Scoliosis diagnosis and treatment","score":0.056699998676776886,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kyphoscoliosis","display_name":"kyphoscoliosis","score":0.9259999990463257},{"id":"https://openalex.org/keywords/nasal-intermittent-positive-pressure-ventilation","display_name":"nasal intermittent positive pressure ventilation","score":0.9879999756813049},{"id":"https://openalex.org/keywords/exercise-capacity","display_name":"exercise capacity","score":0.8949999809265137},{"id":"https://openalex.org/keywords/exercise-induced-hypoxemia","display_name":"exercise-induced hypoxemia","score":0.7820000052452087},{"id":"https://openalex.org/keywords/nocturnal-hypoxemia","display_name":"nocturnal hypoxemia","score":0.8730000257492065},{"id":"https://openalex.org/keywords/respiratory-failure","display_name":"respiratory failure","score":0.7620000243186951},{"id":"https://openalex.org/keywords/6-minute-walk-test","display_name":"6-minute walk test","score":0.7519999742507935},{"id":"https://openalex.org/keywords/arterial-oxygen-saturation","display_name":"arterial oxygen saturation","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C2779405702","wikidata":"https://www.wikidata.org/wiki/Q2856379","display_name":"Kyphoscoliosis","level":3,"score":0.8676590919494629},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7948942184448242},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.634706974029541},{"id":"https://openalex.org/C2779537118","wikidata":"https://www.wikidata.org/wiki/Q618362","display_name":"Arterial blood","level":2,"score":0.6308685541152954},{"id":"https://openalex.org/C2777334680","wikidata":"https://www.wikidata.org/wiki/Q1607611","display_name":"Nocturnal","level":2,"score":0.6106511950492859},{"id":"https://openalex.org/C79959777","wikidata":"https://www.wikidata.org/wiki/Q754333","display_name":"Respiratory minute volume","level":3,"score":0.5208257436752319},{"id":"https://openalex.org/C8213797","wikidata":"https://www.wikidata.org/wiki/Q754250","display_name":"Respiratory rate","level":4,"score":0.5192773342132568},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.4822536110877991},{"id":"https://openalex.org/C2780333948","wikidata":"https://www.wikidata.org/wiki/Q653305","display_name":"Spirometry","level":3,"score":0.4503194987773895},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.4431339502334595},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.43208351731300354},{"id":"https://openalex.org/C2777257755","wikidata":"https://www.wikidata.org/wiki/Q3493813","display_name":"Tidal volume","level":3,"score":0.4316033720970154},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.42729029059410095},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2458379864692688},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.17348608374595642},{"id":"https://openalex.org/C2780955175","wikidata":"https://www.wikidata.org/wiki/Q174857","display_name":"Scoliosis","level":2,"score":0.07126256823539734},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001784","descriptor_name":"Blood Gas Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007385","descriptor_name":"Intermittent Positive-Pressure Ventilation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007738","descriptor_name":"Kyphosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007738","descriptor_name":"Kyphosis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011659","descriptor_name":"Pulmonary Gas Exchange","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012129","descriptor_name":"Respiratory Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012494","descriptor_name":"Sampling Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012600","descriptor_name":"Scoliosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012600","descriptor_name":"Scoliosis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014797","descriptor_name":"Vital Capacity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017079","descriptor_name":"Exercise Tolerance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:15148837","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15148837","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace","raw_type":"Comment"},{"id":"mag:2431326093","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15148837","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2061614170","https://openalex.org/W2062860590","https://openalex.org/W2107254734","https://openalex.org/W2143601787","https://openalex.org/W139683470","https://openalex.org/W4253693889","https://openalex.org/W2091587141","https://openalex.org/W2416753111","https://openalex.org/W2079403894","https://openalex.org/W72242995"],"abstract_inverted_index":{"BACKGROUND:":[0],"Patients":[1],"with":[2,5,68,80,216,224],"severe":[3,81,225],"kyphoscoliosis,":[4],"or":[6,18],"without":[7],"stable":[8],"respiratory":[9,43],"failure,":[10,44],"frequently":[11],"experience":[12],"oxyhaemoglobin":[13,88,161,204],"desaturation":[14,205],"during":[15,27],"sleep,":[16],"exercise,":[17],"both.":[19],"Nasal":[20],"Intermittent":[21],"Positive":[22],"Pressure":[23],"Ventilation":[24],"(NIPPV)":[25],"applied":[26,93],"sleep":[28],"has":[29],"been":[30],"demonstrated":[31],"to":[32,35,60,150,169,188],"be":[33],"able":[34],"control":[36],"nocturnal":[37,69,85,146,217],"desaturations":[38],"and":[39,83,86,128,136,202],"also":[40],"improve":[41],"diurnal":[42],"if":[45],"this":[46,50,57],"is":[47],"present,":[48],"in":[49,74,108,222],"group":[51,76],"of":[52,56,64,77,101,125,140,154,160,214],"patients.":[53],"The":[54,178],"aim":[55],"study":[58],"was":[59,92],"evaluate":[61],"the":[62,138,141,152],"effect":[63],"a":[65,75,97,102],"seven-day":[66],"treatment":[67,215],"NIPPV":[70,91,142,218],"on":[71],"exercise":[72,220],"tolerance":[73],"6":[78],"patients":[79,223],"kyphoscoliosis":[82],"significant":[84],"exercise-induced":[87,203],"desaturation.":[89],"METHODS:":[90],"each":[94,112],"night":[95,155],"for":[96],"week":[98],"by":[99,208],"means":[100],"volume":[103],"cycled":[104],"pressure":[105],"ventilator":[106],"set":[107],"assisted/controlled":[109],"mode.":[110],"In":[111],"patient":[113],"lung":[114],"function,":[115],"daytime":[116,197],"arterial":[117,126,198],"blood":[118,199],"gas":[119,200],"analysis,":[120,201],"overnight":[121],"non":[122],"invasive":[123],"recording":[124],"saturation,":[127],"6-minutes":[129],"walking":[130,180],"test":[131],"were":[132,206],"carried":[133],"out":[134],"initially":[135],"at":[137],"end":[139],"course.":[143],"RESULTS:":[144],"During":[145],"NIPPV,":[147],"as":[148],"compared":[149],"baseline,":[151],"percent":[153],"time":[156],"spent":[157],"below":[158],"90%":[159],"saturation":[162],"significantly":[163,182],"fell":[164],"from":[165,184],"20":[166],"+/-":[167,171,186,190],"12.8":[168],"2.3":[170],"1.9":[172],"(Student":[173],"t-test:":[174],"p":[175],"=":[176,194],"0.017).":[177],"6-minute":[179],"distance":[181],"increased":[183],"244.7":[185],"132.2":[187],"340":[189],"122.3":[191],"m":[192],"(p":[193],"0.0097).":[195],"Spirometry,":[196],"unaffected":[207],"treatment.":[209],"CONCLUSION:":[210],"A":[211],"one-week":[212],"course":[213],"improves":[219],"capacity":[221],"kyphoscoliosis.":[226]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}