{"id":"https://openalex.org/W2430420587","doi":"https://doi.org/10.1177/0885328216656099","title":"The impact of decellularization agents on renal tissue extracellular matrix","display_name":"The impact of decellularization agents on renal tissue extracellular matrix","publication_year":2016,"publication_date":"2016-06-16","ids":{"openalex":"https://openalex.org/W2430420587","doi":"https://doi.org/10.1177/0885328216656099","mag":"2430420587","pmid":"https://pubmed.ncbi.nlm.nih.gov/27312837"},"language":"en","primary_location":{"id":"doi:10.1177/0885328216656099","doi":"https://doi.org/10.1177/0885328216656099","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0885328216656099","pdf_url":null,"source":{"id":"https://openalex.org/S89326922","display_name":"Journal of Biomaterials Applications","issn_l":"0885-3282","issn":["0885-3282","1530-8022"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomaterials Applications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019972181","display_name":"Nafiseh Poornejad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nafiseh Poornejad","raw_affiliation_strings":["Department of Chemical Engineering, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005932181","display_name":"Lara B. Schaumann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lara B Schaumann","raw_affiliation_strings":["Department of Chemical Engineering, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078835630","display_name":"Evan Buckmiller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evan M Buckmiller","raw_affiliation_strings":["Department of Genetics and Biotechnology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Biotechnology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055476014","display_name":"Nima Momtahan","orcid":"https://orcid.org/0000-0002-4220-2351","observed_orcids":["https://orcid.org/0000-0002-4220-2351"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nima Momtahan","raw_affiliation_strings":["Department of Chemical Engineering, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006432458","display_name":"Jason R. Gassman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason R Gassman","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041902544","display_name":"Ho Hin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ho Hin Ma","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110180345","display_name":"Beverly L. Roeder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beverly L Roeder","raw_affiliation_strings":["Department of Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009991971","display_name":"Paul R. Reynolds","orcid":"https://orcid.org/0000-0002-0931-3025","observed_orcids":["https://orcid.org/0000-0002-0931-3025"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul R Reynolds","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002306237","display_name":"Alonzo D. Cook","orcid":"https://orcid.org/0000-0002-6032-4926","observed_orcids":["https://orcid.org/0000-0002-6032-4926"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alonzo D Cook","raw_affiliation_strings":["Department of Chemical Engineering, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5002306237"],"corresponding_institution_ids":["https://openalex.org/I100005738"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":7.01,"has_fulltext":false,"cited_by_count":78,"citation_normalized_percentile":{"value":0.97165168,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"31","issue":"4","first_page":"521","last_page":"533"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/decellularization","display_name":"decellularization","score":0.9440000057220459},{"id":"https://openalex.org/keywords/renal-extracellular-matrix","display_name":"renal extracellular matrix","score":0.8230000138282776},{"id":"https://openalex.org/keywords/kidney-tissue-engineering","display_name":"kidney tissue engineering","score":0.6010000109672546},{"id":"https://openalex.org/keywords/sodium-hydroxide","display_name":"sodium hydroxide","score":0.9409999847412109},{"id":"https://openalex.org/keywords/peracetic-acid","display_name":"peracetic acid","score":0.9879999756813049},{"id":"https://openalex.org/keywords/triton-x-100","display_name":"Triton X-100","score":1.0},{"id":"https://openalex.org/keywords/sodium-dodecyl-sulfate","display_name":"sodium dodecyl sulfate","score":0.996999979019165},{"id":"https://openalex.org/keywords/trypsin-edta","display_name":"trypsin-EDTA","score":0.9940000176429749},{"id":"https://openalex.org/keywords/glycosaminoglycans","display_name":"glycosaminoglycans","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fibroblast-growth-factor","display_name":"fibroblast growth factor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/recellularization","display_name":"recellularization","score":0.8529999852180481},{"id":"https://openalex.org/keywords/porcine-kidney","display_name":"porcine kidney","score":0.7789999842643738}],"concepts":[{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.97968590259552},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.7834205627441406},{"id":"https://openalex.org/C2777309684","wikidata":"https://www.wikidata.org/wiki/Q375140","display_name":"Peracetic acid","level":3,"score":0.7141690254211426},{"id":"https://openalex.org/C38240268","wikidata":"https://www.wikidata.org/wiki/Q17125118","display_name":"Trypsinization","level":4,"score":0.610905110836029},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5669471621513367},{"id":"https://openalex.org/C153074725","wikidata":"https://www.wikidata.org/wiki/Q407553","display_name":"Glycosaminoglycan","level":2,"score":0.5634159445762634},{"id":"https://openalex.org/C2778913249","wikidata":"https://www.wikidata.org/wiki/Q422241","display_name":"Sodium dodecyl sulfate","level":2,"score":0.5392701625823975},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.4976835548877716},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.497632771730423},{"id":"https://openalex.org/C2780381497","wikidata":"https://www.wikidata.org/wiki/Q463418","display_name":"Fibroblast","level":3,"score":0.4929356575012207},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.46643996238708496},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4519006609916687},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.4486919045448303},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3743289113044739},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.31342267990112305},{"id":"https://openalex.org/C2780340462","wikidata":"https://www.wikidata.org/wiki/Q127450","display_name":"Trypsin","level":3,"score":0.30205202102661133},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25165849924087524},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15249484777450562},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1046873927116394},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.09972813725471497},{"id":"https://openalex.org/C533411734","wikidata":"https://www.wikidata.org/wiki/Q171877","display_name":"Hydrogen peroxide","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002458","descriptor_name":"Cell Fractionation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002474","descriptor_name":"Cell-Free System","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008422","descriptor_name":"Materials Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013501","descriptor_name":"Surface-Active Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1177/0885328216656099","doi":"https://doi.org/10.1177/0885328216656099","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0885328216656099","pdf_url":null,"source":{"id":"https://openalex.org/S89326922","display_name":"Journal of Biomaterials Applications","issn_l":"0885-3282","issn":["0885-3282","1530-8022"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomaterials Applications","raw_type":"journal-article"},{"id":"pmid:27312837","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27312837","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomaterials applications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309475","display_name":"Northwestern University","ror":"https://ror.org/000e0be47"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W1125180050","https://openalex.org/W1137009008","https://openalex.org/W1533363236","https://openalex.org/W1846679141","https://openalex.org/W1967540288","https://openalex.org/W1969456018","https://openalex.org/W1974859278","https://openalex.org/W1979057640","https://openalex.org/W1982413446","https://openalex.org/W1984133400","https://openalex.org/W1987602789","https://openalex.org/W1987626869","https://openalex.org/W1994412421","https://openalex.org/W1999579326","https://openalex.org/W2001502638","https://openalex.org/W2002230244","https://openalex.org/W2008565536","https://openalex.org/W2011590786","https://openalex.org/W2012732104","https://openalex.org/W2017070241","https://openalex.org/W2018599317","https://openalex.org/W2019336268","https://openalex.org/W2022999860","https://openalex.org/W2027732308","https://openalex.org/W2030158820","https://openalex.org/W2034446023","https://openalex.org/W2042510811","https://openalex.org/W2045830142","https://openalex.org/W2050852585","https://openalex.org/W2054680082","https://openalex.org/W2059127559","https://openalex.org/W2059366516","https://openalex.org/W2059486645","https://openalex.org/W2064890385","https://openalex.org/W2074519869","https://openalex.org/W2077664488","https://openalex.org/W2079165554","https://openalex.org/W2084112522","https://openalex.org/W2085289337","https://openalex.org/W2101228997","https://openalex.org/W2106001254","https://openalex.org/W2110549425","https://openalex.org/W2118176349","https://openalex.org/W2121719770","https://openalex.org/W2133476128","https://openalex.org/W2136530946","https://openalex.org/W2144253718","https://openalex.org/W2168539681","https://openalex.org/W2175808656","https://openalex.org/W2180284487","https://openalex.org/W2317400971","https://openalex.org/W2320446888","https://openalex.org/W2401073297","https://openalex.org/W4230240787"],"related_works":["https://openalex.org/W2605851381","https://openalex.org/W2317400971","https://openalex.org/W2112956677","https://openalex.org/W2351717985","https://openalex.org/W3109878196","https://openalex.org/W4313545732","https://openalex.org/W2401073297","https://openalex.org/W4229032668","https://openalex.org/W4407641789","https://openalex.org/W2139320982"],"abstract_inverted_index":{"The":[0,97,138,237],"combination":[1],"of":[2,16,20,66,94,112,169,203,212,221,244,251],"patient-specific":[3],"cells":[4,37],"with":[5,234],"scaffolds":[6],"obtained":[7],"from":[8],"natural":[9],"sources":[10],"may":[11],"result":[12],"in":[13,28,108,153,166,187],"improved":[14],"regeneration":[15],"human":[17],"tissues.":[18],"Decellularization":[19],"the":[21,25,58,64,101,109,123,147,172,207,216,224,241,249,261,265],"native":[22],"tissue":[23,89],"is":[24],"first":[26],"step":[27],"this":[29,62],"technology.":[30],"Effective":[31],"decellularization":[32,68],"uses":[33],"agents":[34,69,182,247],"that":[35],"lyse":[36],"and":[38,84,106,115,133,157,162,171,176,193,248],"remove":[39],"all":[40],"cellular":[41,50,189,204],"materials,":[42],"leaving":[43],"intact":[44],"collagenous":[45,128],"extracellular":[46],"matrices":[47],"(ECMs).":[48],"Removing":[49],"remnants":[51],"prevents":[52],"an":[53,253],"immune":[54],"response":[55],"while":[56,263],"preserving":[57],"underlying":[59],"structure.":[60],"In":[61],"study,":[63],"impact":[65],"five":[67],"(0.1":[70],"N":[71],"NaOH,":[72],"1%":[73,79],"peracetic":[74,196],"acid,":[75,197],"3%":[76],"Triton":[77,163],"X-100,":[78],"sodium":[80],"dodecyl":[81],"sulfate":[82],"(SDS),":[83],"0.05%":[85],"trypsin/EDTA)":[86],"on":[87],"renal":[88,222],"was":[90,227],"examined":[91],"using":[92,219],"slices":[93,220],"porcine":[95],"kidneys.":[96],"NaOH":[98,192,225],"solution":[99,140],"induced":[100],"most":[102,124,173],"efficient":[103,186],"cell":[104,113,245,269],"removal,":[105],"resulted":[107,152,165],"highest":[110],"amount":[111],"viability":[114],"proliferation":[116],"after":[117,214],"recellularization,":[118],"although":[119],"it":[120,151],"also":[121],"produced":[122],"significant":[125,242],"damage":[126,145,259],"to":[127,142,146,229,256,260,267],"fiber":[129],"networks,":[130],"glycosaminoglycans":[131],"(GAGs)":[132],"fibroblast":[134],"growth":[135],"factor":[136],"(FGF).":[137],"SDS":[139],"led":[141],"less":[143,158],"severe":[144],"ECM":[148,262],"structure":[149],"but":[150],"lower":[154],"metabolic":[155],"activity":[156],"proliferation.":[159],"Peracetic":[160],"acid":[161],"X-100":[164],"minimum":[167],"disruption":[168],"ECMs":[170],"preserved":[174],"GAGs":[175],"FGF.":[177],"However,":[178],"these":[179],"last":[180],"two":[181],"were":[183],"not":[184],"as":[185,191],"removing":[188],"materials":[190],"SDS,":[194],"especially":[195],"which":[198],"left":[199],"more":[200],"than":[201],"80%":[202],"material":[205],"within":[206],"ECM.":[208],"As":[209],"a":[210,231],"proof":[211],"principle,":[213],"completing":[215],"comparison":[217],"studies":[218],"ECM,":[223],"process":[226],"used":[228],"decellularize":[230],"whole":[232],"kidney,":[233],"good":[235],"results.":[236],"overall":[238],"results":[239],"demonstrate":[240],"effect":[243],"lysing":[246],"importance":[250],"developing":[252],"optimized":[254],"protocol":[255],"avoid":[257],"extensive":[258],"retaining":[264],"ability":[266],"support":[268],"growth.":[270]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":10}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}