{"id":"https://openalex.org/W242728265","doi":null,"title":"The role of reactive oxygen species in traumatic brain injury : Experimental studies in the rat","display_name":"The role of reactive oxygen species in traumatic brain injury : Experimental studies in the rat","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W242728265","mag":"242728265"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:uu-683","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-683","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-683","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009788180","display_name":"Niklas Marklund","orcid":"https://orcid.org/0000-0002-9797-5626","observed_orcids":["https://orcid.org/0000-0002-9797-5626"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Niklas Marklund","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9797-5626","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5009788180"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.8539999723434448},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":1.0},{"id":"https://openalex.org/keywords/nitrones","display_name":"nitrones","score":0.6850000023841858},{"id":"https://openalex.org/keywords/pbn","display_name":"PBN","score":0.7760000228881836},{"id":"https://openalex.org/keywords/fluid-percussion-injury","display_name":"fluid percussion injury","score":0.7860000133514404},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.878000020980835},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.5239999890327454},{"id":"https://openalex.org/keywords/regional-cerebral-blood-flow","display_name":"regional cerebral blood flow","score":0.8130000233650208},{"id":"https://openalex.org/keywords/glucose-uptake","display_name":"glucose uptake","score":0.7419999837875366},{"id":"https://openalex.org/keywords/p-hydroxybenzoic-acid","display_name":"p-hydroxybenzoic acid","score":0.8140000104904175},{"id":"https://openalex.org/keywords/microdialysis","display_name":"microdialysis","score":0.8199999928474426},{"id":"https://openalex.org/keywords/ros-detection","display_name":"ROS detection","score":0.8140000104904175},{"id":"https://openalex.org/keywords/cognitive-outcomes","display_name":"cognitive outcomes","score":0.8840000033378601}],"concepts":[{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.8017061948776245},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6041635870933533},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5793071985244751},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.5651325583457947},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.5348623394966125},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.4536241888999939},{"id":"https://openalex.org/C2781458332","wikidata":"https://www.wikidata.org/wiki/Q720026","display_name":"Brain damage","level":2,"score":0.43815332651138306},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3533979058265686},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2622360289096832},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.21739119291305542},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.06630775332450867}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:uu-683","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-683","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:242728265","doi":null,"is_oa":false,"landing_page_url":"http://www.diva-portal.org/smash/record.jsf?pid=diva2:168234","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:uu-683","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-683","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":340,"referenced_works":["https://openalex.org/W2510997","https://openalex.org/W9655650","https://openalex.org/W13863626","https://openalex.org/W18740259","https://openalex.org/W24370305","https://openalex.org/W33951803","https://openalex.org/W41215289","https://openalex.org/W67770790","https://openalex.org/W73575283","https://openalex.org/W74420308","https://openalex.org/W87832077","https://openalex.org/W109036740","https://openalex.org/W207654541","https://openalex.org/W303715455","https://openalex.org/W328479749","https://openalex.org/W1499834471","https://openalex.org/W1504288624","https://openalex.org/W1517525911","https://openalex.org/W1522782595","https://openalex.org/W1535816350","https://openalex.org/W1536213364","https://openalex.org/W1536773986","https://openalex.org/W1568752613","https://openalex.org/W1569629748","https://openalex.org/W1571964755","https://openalex.org/W1598606175","https://openalex.org/W1601923831","https://openalex.org/W1629254220","https://openalex.org/W1656784884","https://openalex.org/W1661017478","https://openalex.org/W1666499734","https://openalex.org/W1757543239","https://openalex.org/W1760228838","https://openalex.org/W1784600579","https://openalex.org/W1815348286","https://openalex.org/W1852779649","https://openalex.org/W1887482671","https://openalex.org/W1910491774","https://openalex.org/W1913875286","https://openalex.org/W1964187920","https://openalex.org/W1964919653","https://openalex.org/W1965078091","https://openalex.org/W1965173449","https://openalex.org/W1965179669","https://openalex.org/W1965336187","https://openalex.org/W1966558330","https://openalex.org/W1967148805","https://openalex.org/W1967544492","https://openalex.org/W1967889235","https://openalex.org/W1968210150","https://openalex.org/W1968829206","https://openalex.org/W1969023471","https://openalex.org/W1969343230","https://openalex.org/W1969512951","https://openalex.org/W1970392661","https://openalex.org/W1970413507","https://openalex.org/W1970761811","https://openalex.org/W1970863115","https://openalex.org/W1971938856","https://openalex.org/W1972608048","https://openalex.org/W1974252208","https://openalex.org/W1974633644","https://openalex.org/W1975070097","https://openalex.org/W1975634111","https://openalex.org/W1975716726","https://openalex.org/W1977188134","https://openalex.org/W1979362523","https://openalex.org/W1979470828","https://openalex.org/W1979840189","https://openalex.org/W1979986609","https://openalex.org/W1981082943","https://openalex.org/W1981425827","https://openalex.org/W1982386154","https://openalex.org/W1982583160","https://openalex.org/W1982687156","https://openalex.org/W1983455034","https://openalex.org/W1983690076","https://openalex.org/W1984616391","https://openalex.org/W1984857909","https://openalex.org/W1984950757","https://openalex.org/W1985243368","https://openalex.org/W1985285096","https://openalex.org/W1985555928","https://openalex.org/W1985722784","https://openalex.org/W1985736394","https://openalex.org/W1985788035","https://openalex.org/W1985815419","https://openalex.org/W1985853969","https://openalex.org/W1987018561","https://openalex.org/W1987036493","https://openalex.org/W1987787017","https://openalex.org/W1987999833","https://openalex.org/W1988414146","https://openalex.org/W1988603061","https://openalex.org/W1989378067","https://openalex.org/W1989812133","https://openalex.org/W1990188785","https://openalex.org/W1990755486","https://openalex.org/W1990772447","https://openalex.org/W1991162927","https://openalex.org/W1991481781","https://openalex.org/W1992229482","https://openalex.org/W1993257224","https://openalex.org/W1993889646","https://openalex.org/W1994150905","https://openalex.org/W1996125369","https://openalex.org/W1996375992","https://openalex.org/W1996614758","https://openalex.org/W1997251774","https://openalex.org/W1997312851","https://openalex.org/W1999169806","https://openalex.org/W2001135895","https://openalex.org/W2002769318","https://openalex.org/W2003147009","https://openalex.org/W2003159627","https://openalex.org/W2003213627","https://openalex.org/W2006652614","https://openalex.org/W2007348580","https://openalex.org/W2007562867","https://openalex.org/W2008453013","https://openalex.org/W2008710849","https://openalex.org/W2008935907","https://openalex.org/W2009166918","https://openalex.org/W2009294827","https://openalex.org/W2009530141","https://openalex.org/W2009792814","https://openalex.org/W2011320585","https://openalex.org/W2012370852","https://openalex.org/W2013700204","https://openalex.org/W2014083372","https://openalex.org/W2014681568","https://openalex.org/W2015268116","https://openalex.org/W2015312259","https://openalex.org/W2016316143","https://openalex.org/W2016871397","https://openalex.org/W2017765141","https://openalex.org/W2019114766","https://openalex.org/W2019544787","https://openalex.org/W2020338889","https://openalex.org/W2020569812","https://openalex.org/W2021218882","https://openalex.org/W2022647670","https://openalex.org/W2023105087","https://openalex.org/W2023468397","https://openalex.org/W2024267786","https://openalex.org/W2024867072","https://openalex.org/W2025372788","https://openalex.org/W2025446345","https://openalex.org/W2026672310","https://openalex.org/W2027006803","https://openalex.org/W2028608275","https://openalex.org/W2029094008","https://openalex.org/W2029430119","https://openalex.org/W2030312267","https://openalex.org/W2030704464","https://openalex.org/W2032350023","https://openalex.org/W2032545494","https://openalex.org/W2034425798","https://openalex.org/W2034668199","https://openalex.org/W2035271664","https://openalex.org/W2036393894","https://openalex.org/W2036802953","https://openalex.org/W2038226852","https://openalex.org/W2038664762","https://openalex.org/W2039188961","https://openalex.org/W2039471102","https://openalex.org/W2040429969","https://openalex.org/W2040685668","https://openalex.org/W2041204070","https://openalex.org/W2041391753","https://openalex.org/W2041933034","https://openalex.org/W2042808523","https://openalex.org/W2042958071","https://openalex.org/W2043423869","https://openalex.org/W2043804359","https://openalex.org/W2044326611","https://openalex.org/W2045410354","https://openalex.org/W2046128187","https://openalex.org/W2046204149","https://openalex.org/W2046242053","https://openalex.org/W2046331318","https://openalex.org/W2046613651","https://openalex.org/W2047296068","https://openalex.org/W2047482700","https://openalex.org/W2047906602","https://openalex.org/W2048083256","https://openalex.org/W2048180641","https://openalex.org/W2049189117","https://openalex.org/W2049232502","https://openalex.org/W2049428746","https://openalex.org/W2050166658","https://openalex.org/W2050843787","https://openalex.org/W2051600991","https://openalex.org/W2052771562","https://openalex.org/W2052853635","https://openalex.org/W2052862743","https://openalex.org/W2055112763","https://openalex.org/W2055271934","https://openalex.org/W2055298543","https://openalex.org/W2055742593","https://openalex.org/W2055947965","https://openalex.org/W2056027186","https://openalex.org/W2056180447","https://openalex.org/W2056380367","https://openalex.org/W2057621984","https://openalex.org/W2058137293","https://openalex.org/W2058608900","https://openalex.org/W2059222994","https://openalex.org/W2059580764","https://openalex.org/W2059640915","https://openalex.org/W2060433627","https://openalex.org/W2060697601","https://openalex.org/W2061450724","https://openalex.org/W2061497413","https://openalex.org/W2062482333","https://openalex.org/W2062566813","https://openalex.org/W2062754118","https://openalex.org/W2063960864","https://openalex.org/W2064196264","https://openalex.org/W2065264404","https://openalex.org/W2065730275","https://openalex.org/W2066277926","https://openalex.org/W2066876892","https://openalex.org/W2067280618","https://openalex.org/W2067624621","https://openalex.org/W2067668489","https://openalex.org/W2067682780","https://openalex.org/W2068121825","https://openalex.org/W2068235202","https://openalex.org/W2068493439","https://openalex.org/W2069471046","https://openalex.org/W2069767202","https://openalex.org/W2069972562","https://openalex.org/W2070114967","https://openalex.org/W2070139095","https://openalex.org/W2070719568","https://openalex.org/W2071896237","https://openalex.org/W2072643276","https://openalex.org/W2072698244","https://openalex.org/W2074035433","https://openalex.org/W2074572230","https://openalex.org/W2074595931","https://openalex.org/W2075212315","https://openalex.org/W2077529180","https://openalex.org/W2078070903","https://openalex.org/W2078603857","https://openalex.org/W2079413727","https://openalex.org/W2080279037","https://openalex.org/W2080433044","https://openalex.org/W2081219459","https://openalex.org/W2081230041","https://openalex.org/W2083863274","https://openalex.org/W2084159987","https://openalex.org/W2084546931","https://openalex.org/W2085360535","https://openalex.org/W2085365806","https://openalex.org/W2085459880","https://openalex.org/W2085542125","https://openalex.org/W2085664820","https://openalex.org/W2086545066","https://openalex.org/W2087916050","https://openalex.org/W2088084771","https://openalex.org/W2088387923","https://openalex.org/W2088519488","https://openalex.org/W2089691927","https://openalex.org/W2089870793","https://openalex.org/W2090544950","https://openalex.org/W2090678667","https://openalex.org/W2090821389","https://openalex.org/W2090872647","https://openalex.org/W2091112040","https://openalex.org/W2092116887","https://openalex.org/W2092345297","https://openalex.org/W2092434834","https://openalex.org/W2092553541","https://openalex.org/W2092721077","https://openalex.org/W2093281755","https://openalex.org/W2093708814","https://openalex.org/W2094216072","https://openalex.org/W2094334993","https://openalex.org/W2094544671","https://openalex.org/W2095150799","https://openalex.org/W2096186513","https://openalex.org/W2096821918","https://openalex.org/W2098015360","https://openalex.org/W2099484254","https://openalex.org/W2101462909","https://openalex.org/W2102632252","https://openalex.org/W2103105379","https://openalex.org/W2104233676","https://openalex.org/W2104730217","https://openalex.org/W2105215015","https://openalex.org/W2112027230","https://openalex.org/W2114798577","https://openalex.org/W2115577166","https://openalex.org/W2117104323","https://openalex.org/W2119332587","https://openalex.org/W2122720869","https://openalex.org/W2125683177","https://openalex.org/W2126608948","https://openalex.org/W2127002164","https://openalex.org/W2129342530","https://openalex.org/W2131347780","https://openalex.org/W2132889264","https://openalex.org/W2133739669","https://openalex.org/W2135781323","https://openalex.org/W2138302361","https://openalex.org/W2141185284","https://openalex.org/W2141537184","https://openalex.org/W2142084940","https://openalex.org/W2142101451","https://openalex.org/W2144983731","https://openalex.org/W2145748909","https://openalex.org/W2148464749","https://openalex.org/W2150833402","https://openalex.org/W2150854367","https://openalex.org/W2152426226","https://openalex.org/W2155747798","https://openalex.org/W2158406932","https://openalex.org/W2158600655","https://openalex.org/W2160099189","https://openalex.org/W2162892324","https://openalex.org/W2165083422","https://openalex.org/W2165292984","https://openalex.org/W2168460845","https://openalex.org/W2170604411","https://openalex.org/W2171723910","https://openalex.org/W2187723987","https://openalex.org/W2222897991","https://openalex.org/W2243480508","https://openalex.org/W2259406371","https://openalex.org/W2273757890","https://openalex.org/W2323869711","https://openalex.org/W2402003540","https://openalex.org/W2413399078","https://openalex.org/W2414181153","https://openalex.org/W2432127637","https://openalex.org/W2483744482","https://openalex.org/W2739532201","https://openalex.org/W4300794036"],"related_works":["https://openalex.org/W74149202","https://openalex.org/W1980818239","https://openalex.org/W1520169101","https://openalex.org/W1524572279","https://openalex.org/W1963689012","https://openalex.org/W2059580764","https://openalex.org/W2071979064","https://openalex.org/W2025219416","https://openalex.org/W2061314122","https://openalex.org/W2029993645"],"abstract_inverted_index":{"Traumatic":[0],"brain":[1,282],"injury":[2,73,175,301],"(TBI)":[3],"is":[4,31,51],"a":[5,141,177,191,212,247,269,307,330,334],"major":[6],"cause":[7],"of":[8,17,28,43,59,75,93,106,130,168,284],"mortality":[9],"and":[10,23,69,89,117,132,190,203,218,228,273,320,323],"disability.":[11],"As":[12],"common":[13],"sequelae":[14],"in":[15,56,77,108,156,183,187,193,215,238,250,258,299,337],"survivors":[16],"TBI":[18,29,76],"are":[19],"disabling":[20],"functional,":[21],"emotional":[22],"cognitive":[24,118,152],"disturbances,":[25],"improved":[26,115,146,151,321],"treatment":[27,39,327],"patients":[30],"urgently":[32],"needed.":[33],"At":[34,209],"present,":[35],"no":[36,280],"neuroprotective":[37,335],"pharmacological":[38],"exists.":[40],"The":[41,244],"formation":[42,252,278],"oxygen-centered":[44],"free":[45],"radicals,":[46],"reactive":[47],"oxygen":[48],"species":[49],"(ROS),":[50],"considered":[52],"an":[53,184,256,296],"important":[54,297],"event":[55],"the":[57,62,65,90,104,157,166,259,300],"pathophysiology":[58],"TBI.":[60,109,304,338],"In":[61,268,292],"present":[63],"thesis,":[64],"fluid":[66],"percussion":[67],"(FPI)":[68],"controlled":[70,122],"cortical":[71,123],"contusion":[72,124],"models":[74],"rats":[78],"were":[79,98,224],"used.":[80],"Two":[81],"nitrone":[82,87,96],"radical":[83],"scavengers,":[84],"\u03b1-Phenyl-N-tert":[85],"-butyl":[86],"(PBN)":[88],"sulfonated":[91],"analogue":[92],"PBN,":[94],"2-sulfophenyl-N-tert-butyl":[95],"(S-PBN),":[97],"used":[99],"as":[100,154,253,333],"tools":[101],"to":[102],"study":[103],"role":[105,298],"ROS":[107,234,251,294,310,318],"Pre-treatment":[110],"with":[111,127,163,240,312],"PBN":[112,131,164,227,272],"(30":[113],"mg/kg)":[114],"morphological":[116,147,324],"outcome":[119,153],"after":[120,137,174,266,303],"severe":[121],"injury.":[125,267],"Treatment":[126],"equimolar":[128],"doses":[129],"S-PBN":[133,150,229,274,285],"administered":[134],"30":[135,287],"min":[136,265,290],"FPI":[138,181],"followed":[139],"by":[140,200,226,255],"24":[142,172],"h":[143],"intravenous":[144],"infusion":[145],"outcome.":[148,325],"Only":[149],"assessed":[155,199,254],"Morris":[158],"Water":[159],"Maze.":[160],"Surprisingly,":[161],"pre-treatment":[162],"increased":[165,317],"number":[167],"apoptotic":[169],"neurons":[170],"at":[171,286],"hours":[173],"despite":[176,279],"reduced":[178,276],"lesion":[179],"volume.":[180],"resulted":[182],"early":[185],"increase":[186,249,257],"glucose":[188,216],"uptake":[189,217],"reduction":[192,214],"regional":[194],"cerebral":[195],"blood":[196],"flow":[197],"(rCBF)":[198],"fluoro-2-deoxyglucose":[201],"(FDG)":[202],"hexamethylpropylene":[204],"amine":[205],"oxime":[206],"(HMPAO)":[207],"autoradiography.":[208],"12":[210],"h,":[211],"marked":[213,248],"rCBF":[219],"ensued.":[220],"These":[221],"TBI-induced":[222],"changes":[223],"attenuated":[225],"pre-treatment.":[230],"A":[231],"method":[232,308],"for":[233,309],"detection":[235,311],"using":[236],"4-hydroxybenzoate":[237],"conjunction":[239],"microdialysis":[241],"was":[242],"evaluated.":[243],"results":[245],"showed":[246],"single":[260],"adduct":[261],"3,4-DHBA,":[262],"lasting":[263],"90":[264],"separate":[270],"study,":[271],"equally":[275],"3,4-DHBA":[277],"detectable":[281],"concentrations":[283],"or":[288],"60":[289],"post-injury.":[291],"conclusion,":[293],"play":[295],"process":[302],"We":[305],"report":[306],"potential":[313,332],"clinical":[314,331],"utility.":[315],"Nitrones":[316],"elimination":[319],"functional":[322],"Nitrone":[326],"may":[328],"have":[329],"concept":[336]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
