{"id":"https://openalex.org/W2425221220","doi":null,"title":"[Cytokines in vaccines and interferon preparations].","display_name":"[Cytokines in vaccines and interferon preparations].","publication_year":1996,"publication_date":"1996-11-01","ids":{"openalex":"https://openalex.org/W2425221220","mag":"2425221220","pmid":"https://pubmed.ncbi.nlm.nih.gov/9103075"},"language":"ru","primary_location":{"id":"pmid:9103075","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9103075","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhurnal mikrobiologii, epidemiologii i immunobiologii","raw_type":"English Abstract"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038140772","display_name":"S E Akol'zina","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S E Akol'zina","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040970290","display_name":"\u0416. \u0418. \u0410\u0432\u0434\u0435\u0435\u0432\u0430","orcid":"https://orcid.org/0000-0002-9377-1378","observed_orcids":["https://orcid.org/0000-0002-9377-1378"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zh I Avdeeva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082230917","display_name":"Potapnev Mp","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M P Potapnev","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029143155","display_name":"Vozniuk Av","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A V Vozniuk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009623732","display_name":"Nevskaia Lv","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L V Nevskaia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084010298","display_name":"Alpatova Na","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N A Alpatova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035124285","display_name":"Ter-Gabri\u00e9l'iants Gg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G G Ter-Gabri\u00e9l'iants","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5030555780","display_name":"Medunitsyn Nv","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N V Medunitsyn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.20841919,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"6","first_page":"36","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.28049999475479126,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.28049999475479126,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.25589999556541443,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.05889999866485596,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.9419999718666077},{"id":"https://openalex.org/keywords/vaccine-adjuvants","display_name":"vaccine adjuvants","score":0.5759999752044678},{"id":"https://openalex.org/keywords/interferon-preparations","display_name":"interferon preparations","score":0.9539999961853027},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9509999752044678},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8970000147819519},{"id":"https://openalex.org/keywords/rabies-vaccine","display_name":"rabies vaccine","score":0.6690000295639038},{"id":"https://openalex.org/keywords/polio-vaccine","display_name":"polio vaccine","score":0.9800000190734863},{"id":"https://openalex.org/keywords/measles-vaccine","display_name":"measles vaccine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hepatitis-a-vaccine","display_name":"hepatitis A vaccine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cell-lines","display_name":"cell lines","score":0.6669999957084656}],"concepts":[{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7142953276634216},{"id":"https://openalex.org/C89138240","wikidata":"https://www.wikidata.org/wiki/Q3066564","display_name":"Vero cell","level":3,"score":0.6148186922073364},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.6000867486000061},{"id":"https://openalex.org/C2779631682","wikidata":"https://www.wikidata.org/wiki/Q12438936","display_name":"Poliovirus","level":3,"score":0.5659791827201843},{"id":"https://openalex.org/C2776438120","wikidata":"https://www.wikidata.org/wiki/Q79793","display_name":"Measles","level":3,"score":0.5644065737724304},{"id":"https://openalex.org/C2780657872","wikidata":"https://www.wikidata.org/wiki/Q6804161","display_name":"Measles vaccine","level":4,"score":0.45610079169273376},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.43346452713012695},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40702056884765625},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.39933666586875916},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.39395207166671753},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.3267615735530853},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006507","descriptor_name":"Hepatovirus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007372","descriptor_name":"Interferons","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008458","descriptor_name":"Measles Vaccine","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011054","descriptor_name":"Poliovirus Vaccine, Inactivated","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011819","descriptor_name":"Rabies Vaccines","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014761","descriptor_name":"Viral Hepatitis Vaccines","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:9103075","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9103075","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhurnal mikrobiologii, epidemiologii i immunobiologii","raw_type":"English Abstract"},{"id":"mag:2425221220","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9103075","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1969260521","https://openalex.org/W2007478425","https://openalex.org/W1592388192","https://openalex.org/W2059558137","https://openalex.org/W2142975203","https://openalex.org/W2000527283","https://openalex.org/W1797943713","https://openalex.org/W2158827509","https://openalex.org/W2171669982","https://openalex.org/W1975302315"],"abstract_inverted_index":{"Virus":[0],"vaccines":[1],"prepared":[2],"on":[3,26],"the":[4,27,30,42,55,63,72,84,94,102,106],"basis":[5],"of":[6,8,29,44,54,65,71,75,82,86,96,105],"cells":[7],"mammals":[9],"(rabies,":[10],"poliomyelitis,":[11],"measles":[12,67],"and":[13,46,79,89],"hepatitis":[14],"A":[15],"vaccines)":[16],"contain":[17],"cytokines":[18,98],"(IL-1":[19],"beta,":[20],"IL-6,":[21],"TNF-alpha),":[22],"whose":[23],"concentration":[24],"depends":[25],"kind":[28],"vaccine.":[31],"Cell":[32,58],"lines":[33],"(green":[34],"monkey":[35],"kidney":[36],"cells,":[37],"VERO,":[38],"4647),":[39],"used":[40,61,108],"for":[41,62],"preparation":[43],"commercial":[45],"experimental":[47,66],"vaccines,":[48],"do":[49],"not":[50],"produce":[51],"spontaneously":[52],"any":[53],"above":[56],"cytokines.":[57],"line":[59],"L-68,":[60],"manufacture":[64],"vaccine,":[68],"is":[69,99],"capable":[70],"spontaneous":[73],"synthesis":[74],"IL-6.":[76],"In":[77],"Russian":[78],"foreign":[80],"preparations":[81],"interferon":[83],"presence":[85],"IL-1":[87],"beta":[88],"TNF-alpha":[90],"has":[91],"been":[92],"detected;":[93],"content":[95],"these":[97,110],"determined":[100],"by":[101],"specific":[103],"features":[104],"methods":[107],"manufacturing":[109],"preparations.":[111]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}