{"id":"https://openalex.org/W2424964465","doi":null,"title":"[Man and the diversity of his genome. An extraordinary phase in the history of population genetics].","display_name":"[Man and the diversity of his genome. An extraordinary phase in the history of population genetics].","publication_year":1998,"publication_date":"1998-02-01","ids":{"openalex":"https://openalex.org/W2424964465","mag":"2424964465","pmid":"https://pubmed.ncbi.nlm.nih.gov/9769919"},"language":"fr","primary_location":{"id":"pmid:9769919","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9769919","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathologie-biologie","raw_type":"English Abstract"},"volume":null,"type":"other","is_traditional":false,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111679384","display_name":"Luigi Luca Cavalli-Sforza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"L Cavalli-Sforza","raw_affiliation_strings":["Department of Genetics, Stanford University, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Stanford University, California, USA","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111679384"],"corresponding_institution_ids":["https://openalex.org/I97018004"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":"2","first_page":"98","last_page":"102"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-genome-diversity","display_name":"human genome diversity","score":0.6809999942779541},{"id":"https://openalex.org/keywords/dna-markers","display_name":"DNA markers","score":0.9129999876022339},{"id":"https://openalex.org/keywords/microsatellite-markers","display_name":"microsatellite markers","score":0.9940000176429749},{"id":"https://openalex.org/keywords/human-migration-out-of-africa","display_name":"human migration out of Africa","score":0.8109999895095825},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9629999995231628},{"id":"https://openalex.org/keywords/denaturing-high-performance-liquid-chromatography","display_name":"denaturing high-performance liquid chromatography","score":0.7839999794960022},{"id":"https://openalex.org/keywords/human-genome-diversity-project","display_name":"Human Genome Diversity Project","score":0.8980000019073486}],"concepts":[{"id":"https://openalex.org/C61320498","wikidata":"https://www.wikidata.org/wiki/Q265193","display_name":"Microsatellite","level":4,"score":0.6516172885894775},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.600960910320282},{"id":"https://openalex.org/C85721925","wikidata":"https://www.wikidata.org/wiki/Q31151","display_name":"Population genetics","level":3,"score":0.5933630466461182},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5761821866035461},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.5656675696372986},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5620452761650085},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5214078426361084},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4880341589450836},{"id":"https://openalex.org/C81977670","wikidata":"https://www.wikidata.org/wiki/Q585259","display_name":"Genetic diversity","level":3,"score":0.46767908334732056},{"id":"https://openalex.org/C53553401","wikidata":"https://www.wikidata.org/wiki/Q47307","display_name":"Genealogy","level":1,"score":0.35828161239624023},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20839360356330872},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.1659334897994995},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.13305306434631348},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.132938414812088},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.07902973890304565}],"mesh":[{"descriptor_ui":"D000349","descriptor_name":"Africa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005828","descriptor_name":"Genetics, Population","qualifier_ui":"Q000266","qualifier_name":"history","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049673","descriptor_name":"History, 20th Century","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:9769919","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9769919","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathologie-biologie","raw_type":"English Abstract"},{"id":"mag:2424964465","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9769919","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4388325108","https://openalex.org/W2128468605","https://openalex.org/W1588378115","https://openalex.org/W2078947652","https://openalex.org/W2019249381","https://openalex.org/W7096532189","https://openalex.org/W7097423905","https://openalex.org/W7216694193","https://openalex.org/W2144821573","https://openalex.org/W2170445274"],"abstract_inverted_index":{"Population":[0],"genetics":[1],"is":[2,86,137],"almost":[3,67,150],"eighty":[4],"years":[5],"old,":[6],"but":[7,53],"benefited":[8],"only":[9],"very":[10,88],"recently":[11],"from":[12],"the":[13,30,38,61,73,83,96,107,119,153,187,190,195,210],"advantages":[14],"of":[15,32,37,60,65,69,75,81,100,102,122,128,167,173,179,189,197,201],"direct":[16],"DNA":[17,33],"analysis.":[18],"Nevertheless,":[19],"much":[20],"knowledge":[21],"had":[22],"already":[23],"accumulated":[24],"and":[25,124,142,156,182,193],"was":[26,112],"completely":[27,164],"confirmed":[28],"by":[29,209],"study":[31],"markers.":[34],"Major":[35],"benefits":[36],"latter":[39],"came":[40],"with":[41,50,57],"microsatellites.":[42],"It":[43],"allowed":[44],"to":[45,152,176],"discover":[46],"an":[47],"error":[48],"made":[49,207],"classical":[51,180],"markers":[52,127,181,184],"even":[54],"more":[55],"seriously":[56],"RFLPs,":[58],"because":[59],"practically":[62],"involuntary":[63],"sampling":[64],"individuals":[66],"exclusively":[68,151],"European":[70],"origin":[71],"for":[72,91,139],"detection":[74,141],"polymorphisms.":[76],"Among":[77],"other":[78],"evolutionary":[79],"application":[80],"microsatellites,":[82],"most":[84],"attractive":[85],"their":[87,140],"recent":[89,97],"use":[90],"dating":[92],"population":[93,202],"separations":[94],"during":[95],"migration":[98],"out":[99],"Africa":[101],"modern":[103],"humans.":[104],"They":[105],"confirm":[106],"theory":[108],"that":[109],"this":[110,129],"expansion":[111],"quite":[113],"recent.":[114],"Single":[115],"nucleotide":[116],"substitutions":[117],"are":[118],"major":[120],"material":[121],"evolution,":[123],"so":[125],"far":[126],"kind":[130],"were":[131],"rare.":[132],"A":[133],"new":[134,165],"method,":[135],"DHPLC,":[136],"excellent":[138],"testing.":[143],"In":[144],"humans":[145],"it":[146,160],"has":[147,161],"been":[148],"applied":[149],"Y":[154,168],"chromosome,":[155],"in":[157],"a":[158,163,198],"year":[159],"given":[162],"picture":[166],"chromosome":[169],"genetics.":[170],"Some":[171],"applications":[172],"statistical":[174],"methods":[175],"genetic":[177],"geography":[178],"ADN":[183],"will":[185,205],"show":[186],"power":[188],"geographical":[191],"approach,":[192],"therefore":[194],"need":[196],"wide":[199],"collection":[200],"samples,":[203],"as":[204],"be":[206],"possible":[208],"HGDP":[211],"(Human":[212],"Genome":[213],"Diversity":[214],"Project).":[215]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}