{"id":"https://openalex.org/W2422001908","doi":"https://doi.org/10.1080/13102818.2016.1190945","title":"Comparative evaluation of the Brucella Coombs gel test in laboratory diagnosis of human brucellosis","display_name":"Comparative evaluation of the Brucella Coombs gel test in laboratory diagnosis of human brucellosis","publication_year":2016,"publication_date":"2016-06-16","ids":{"openalex":"https://openalex.org/W2422001908","doi":"https://doi.org/10.1080/13102818.2016.1190945","mag":"2422001908"},"language":"en","primary_location":{"id":"doi:10.1080/13102818.2016.1190945","doi":"https://doi.org/10.1080/13102818.2016.1190945","is_oa":true,"landing_page_url":"https://doi.org/10.1080/13102818.2016.1190945","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/13102818.2016.1190945?needAccess=true","source":{"id":"https://openalex.org/S121023886","display_name":"Biotechnology & Biotechnological Equipment","issn_l":"1310-2818","issn":["1310-2818","1314-3530"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology &amp; Biotechnological Equipment","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/13102818.2016.1190945?needAccess=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100745194","display_name":"Mehmet K\u00f6ro\u011flu","orcid":"https://orcid.org/0000-0001-8101-1104","observed_orcids":["https://orcid.org/0000-0001-8101-1104","https://orcid.org/0000-0001-5069-9479"]},"institutions":[{"id":"https://openalex.org/I103703290","display_name":"Sakarya University","ror":"https://ror.org/04ttnw109","country_code":"TR","type":"education","lineage":["https://openalex.org/I103703290"]},{"id":"https://openalex.org/I4210116985","display_name":"Sakarya E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/02h67ht97","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mehmet Koroglu","raw_affiliation_strings":["Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey","Department of Medical Microbiology, School of Medicine, Sakarya University, Sakarya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]},{"raw_affiliation_string":"Department of Medical Microbiology, School of Medicine, Sakarya University, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035114768","display_name":"\u00d6zlem Aydemir","orcid":"https://orcid.org/0000-0003-4533-6934","observed_orcids":["https://orcid.org/0000-0003-4533-6934"]},"institutions":[{"id":"https://openalex.org/I103703290","display_name":"Sakarya University","ror":"https://ror.org/04ttnw109","country_code":"TR","type":"education","lineage":["https://openalex.org/I103703290"]},{"id":"https://openalex.org/I4210116985","display_name":"Sakarya E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/02h67ht97","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ozlem Akkaya Aydemir","raw_affiliation_strings":["Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002250809","display_name":"Tayfur Demiray","orcid":"https://orcid.org/0000-0003-1161-4684","observed_orcids":["https://orcid.org/0000-0003-1161-4684"]},"institutions":[{"id":"https://openalex.org/I103703290","display_name":"Sakarya University","ror":"https://ror.org/04ttnw109","country_code":"TR","type":"education","lineage":["https://openalex.org/I103703290"]},{"id":"https://openalex.org/I4210116985","display_name":"Sakarya E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/02h67ht97","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Tayfur Demiray","raw_affiliation_strings":["Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085028093","display_name":"\u00dcnal Erkorkmaz","orcid":"https://orcid.org/0000-0002-8497-4704","observed_orcids":["https://orcid.org/0000-0002-8497-4704"]},"institutions":[{"id":"https://openalex.org/I103703290","display_name":"Sakarya University","ror":"https://ror.org/04ttnw109","country_code":"TR","type":"education","lineage":["https://openalex.org/I103703290"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Unal Erkorkmaz","raw_affiliation_strings":["Department of Biostatistics, School of Medicine, Sakarya University, Sakarya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, School of Medicine, Sakarya University, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101909952","display_name":"Ahmet \u00d6zbek","orcid":"https://orcid.org/0000-0001-8938-6533","observed_orcids":["https://orcid.org/0000-0001-8938-6533"]},"institutions":[{"id":"https://openalex.org/I103703290","display_name":"Sakarya University","ror":"https://ror.org/04ttnw109","country_code":"TR","type":"education","lineage":["https://openalex.org/I103703290"]},{"id":"https://openalex.org/I4210116985","display_name":"Sakarya E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/02h67ht97","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ahmet Ozbek","raw_affiliation_strings":["Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey","Department of Medical Microbiology, School of Medicine, Sakarya University, Sakarya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]},{"raw_affiliation_string":"Department of Medical Microbiology, School of Medicine, Sakarya University, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054680172","display_name":"Mustafa Alt\u0131ndi\u015f","orcid":"https://orcid.org/0000-0003-0411-9669","observed_orcids":["https://orcid.org/0000-0003-0411-9669"]},"institutions":[{"id":"https://openalex.org/I103703290","display_name":"Sakarya University","ror":"https://ror.org/04ttnw109","country_code":"TR","type":"education","lineage":["https://openalex.org/I103703290"]},{"id":"https://openalex.org/I4210116985","display_name":"Sakarya E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/02h67ht97","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Mustafa Altindis","raw_affiliation_strings":["Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey","Department of Medical Microbiology, School of Medicine, Sakarya University, Sakarya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Microbiology Laboratory, Sakarya University Research and Education Hospital, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]},{"raw_affiliation_string":"Department of Medical Microbiology, School of Medicine, Sakarya University, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5054680172"],"corresponding_institution_ids":["https://openalex.org/I103703290","https://openalex.org/I4210116985"],"apc_list":{"value":1250,"currency":"GBP","value_usd":1533},"apc_paid":{"value":1250,"currency":"GBP","value_usd":1533},"fwci":0.2333,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.53067794,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"30","issue":"5","first_page":"970","last_page":"975"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11899","display_name":"Brucella: diagnosis, epidemiology, treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11899","display_name":"Brucella: diagnosis, epidemiology, treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-brucellosis","display_name":"human brucellosis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.9350000023841858},{"id":"https://openalex.org/keywords/agglutination-inhibition","display_name":"agglutination inhibition","score":0.746999979019165},{"id":"https://openalex.org/keywords/blocking-antibodies","display_name":"blocking antibodies","score":0.5789999961853027},{"id":"https://openalex.org/keywords/diagnostic-test-comparison","display_name":"diagnostic test comparison","score":0.5329999923706055},{"id":"https://openalex.org/keywords/diagnostic-agreement","display_name":"diagnostic agreement","score":0.4189999997615814},{"id":"https://openalex.org/keywords/screening-test","display_name":"screening test","score":0.3370000123977661}],"concepts":[{"id":"https://openalex.org/C2778986270","wikidata":"https://www.wikidata.org/wiki/Q740056","display_name":"Coombs test","level":3,"score":0.7873532772064209},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.7842894792556763},{"id":"https://openalex.org/C2781429187","wikidata":"https://www.wikidata.org/wiki/Q156050","display_name":"Brucellosis","level":2,"score":0.741669237613678},{"id":"https://openalex.org/C73878171","wikidata":"https://www.wikidata.org/wiki/Q5280305","display_name":"Direct agglutination test","level":4,"score":0.7196961641311646},{"id":"https://openalex.org/C143508840","wikidata":"https://www.wikidata.org/wiki/Q393294","display_name":"Agglutination (biology)","level":3,"score":0.6611472964286804},{"id":"https://openalex.org/C2780767784","wikidata":"https://www.wikidata.org/wiki/Q313358","display_name":"Brucella","level":3,"score":0.6603018045425415},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.5616292357444763},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5067055821418762},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.47803744673728943},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.37653693556785583}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1080/13102818.2016.1190945","doi":"https://doi.org/10.1080/13102818.2016.1190945","is_oa":true,"landing_page_url":"https://doi.org/10.1080/13102818.2016.1190945","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/13102818.2016.1190945?needAccess=true","source":{"id":"https://openalex.org/S121023886","display_name":"Biotechnology & Biotechnological Equipment","issn_l":"1310-2818","issn":["1310-2818","1314-3530"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology &amp; Biotechnological Equipment","raw_type":"journal-article"},{"id":"pmh:oai:acikerisim.sakarya.edu.tr:20.500.12619/65462","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.1080/13102818.2016.1190945","pdf_url":null,"source":{"id":"https://openalex.org/S7407055276","display_name":"Sakarya \u00dcniversitesi Kurumsal A\u00e7\u0131k Akademik Ar\u015fivi","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:7c5ef9f412b14e6d92b203806f9d890e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7c5ef9f412b14e6d92b203806f9d890e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biotechnology & Biotechnological Equipment, Vol 30, Iss 5, Pp 970-975 (2016)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1080/13102818.2016.1190945","doi":"https://doi.org/10.1080/13102818.2016.1190945","is_oa":true,"landing_page_url":"https://doi.org/10.1080/13102818.2016.1190945","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/13102818.2016.1190945?needAccess=true","source":{"id":"https://openalex.org/S121023886","display_name":"Biotechnology & Biotechnological Equipment","issn_l":"1310-2818","issn":["1310-2818","1314-3530"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology &amp; Biotechnological Equipment","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2422001908.pdf"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W40409475","https://openalex.org/W73831479","https://openalex.org/W1978782500","https://openalex.org/W1992344875","https://openalex.org/W2010539647","https://openalex.org/W2018118048","https://openalex.org/W2027456107","https://openalex.org/W2039099129","https://openalex.org/W2053154970","https://openalex.org/W2087786662","https://openalex.org/W2104724840","https://openalex.org/W2108703084","https://openalex.org/W2145216451","https://openalex.org/W2145265550","https://openalex.org/W2161008197","https://openalex.org/W2411183775","https://openalex.org/W2428794385","https://openalex.org/W4211033510"],"related_works":["https://openalex.org/W3002028232","https://openalex.org/W2411183775","https://openalex.org/W2299397065","https://openalex.org/W3023577945","https://openalex.org/W2577266433","https://openalex.org/W2443725653","https://openalex.org/W3111275881","https://openalex.org/W3130201976","https://openalex.org/W2229930047","https://openalex.org/W7161920425"],"abstract_inverted_index":{"Brucellosis":[0],"is":[1,47,77,176,193],"widespread":[2],"among":[3],"humans":[4],"and":[5,21,60,92,105,128,151,158,160,180,182],"animals.":[6],"Diagnosis":[7],"of":[8,70,74,123],"brucellosis":[9],"mostly":[10],"depends":[11,61],"on":[12,62],"serological":[13,68],"methods.":[14],"Serological":[15],"tests":[16,31],"are":[17,32],"preferred":[18],"over":[19],"time-consuming":[20],"hazardous":[22],"bacterial":[23],"cultures":[24],"in":[25,57,114,187],"routine":[26],"laboratory":[27],"practice.":[28],"However,":[29],"these":[30],"somehow":[33],"challenging":[34],"due":[35],"to":[36,178],"\u2018incomplete/blocking":[37],"antibodies\u2019":[38],"that":[39,51],"prevent":[40],"agglutination.":[41],"Brucella":[42],"Coombs":[43,53,90],"gel":[44,58,63],"test":[45,50,150],"(BCGT)":[46],"newly":[48],"developed":[49],"contains":[52],"antibodies":[54],"(anti-human":[55],"IgG)":[56],"microtubes":[59],"centrifugation":[64],"methods":[65],"for":[66,102,108,133,196],"the":[67,75,109,115,168],"diagnosis":[69],"brucellosis.":[71],"Here,":[72],"performance":[73],"BCGT":[76,149,159,175],"compared":[78],"with":[79,89],"standard":[80,85],"serum":[81,86],"tube":[82,87],"agglutination":[83,88,95],"(STA),":[84],"(C-STA)":[91],"immune":[93],"capture":[94],"(Brucellacapt).":[96],"In":[97],"total,":[98],"78":[99],"positive":[100,132],"samples":[101,107,118],"study":[103],"group":[104,111],"16":[106],"control":[110],"were":[112,119,130,140,146],"enrolled":[113],"study.":[116],"The":[117],"tested":[120],"at":[121,126],"dilutions":[122],"1:40\u20131:5120.":[124],"Titres":[125],"1:160":[127,139],"above":[129],"considered":[131,141],"brucellosis,":[134],"whereas":[135],"those":[136],"lower":[137],"than":[138,189],"negative.":[142],"Excellent":[143],"agreement":[144],"levels":[145],"determined":[147],"between":[148],"C-STA":[152],"(\u03ba,":[153,162],"0.894;":[154],"p":[155,164],"<":[156,165],"0.001),":[157,166],"Brucellacapt":[161],"0.802;":[163],"when":[167],"diagnostic":[169],"titre":[170,185],"was":[171],"accepted":[172],"as":[173],"1:160.":[174],"easy":[177],"apply":[179],"interpret":[181],"provides":[183],"reliable":[184],"results":[186],"less":[188],"2":[190],"h.":[191],"It":[192],"also":[194],"advantageous":[195],"screening.":[197]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}