{"id":"https://openalex.org/W2419047331","doi":"https://doi.org/10.11150/kansenshogakuzasshi1970.58.1289","title":"A Double-Blind Clinical Evaluation of Flurbiprofen on Acute Upper Respiratory Tract Inflammation","display_name":"A Double-Blind Clinical Evaluation of Flurbiprofen on Acute Upper Respiratory Tract Inflammation","publication_year":1984,"publication_date":"1984-01-01","ids":{"openalex":"https://openalex.org/W2419047331","doi":"https://doi.org/10.11150/kansenshogakuzasshi1970.58.1289","mag":"2419047331","pmid":"https://pubmed.ncbi.nlm.nih.gov/6442724"},"language":"ja","primary_location":{"id":"doi:10.11150/kansenshogakuzasshi1970.58.1289","doi":"https://doi.org/10.11150/kansenshogakuzasshi1970.58.1289","is_oa":true,"landing_page_url":"https://doi.org/10.11150/kansenshogakuzasshi1970.58.1289","pdf_url":"https://www.jstage.jst.go.jp/article/kansenshogakuzasshi1970/58/12/58_12_1289/_pdf","source":{"id":"https://openalex.org/S4210176383","display_name":"Kansenshogaku zasshi","issn_l":"0387-5911","issn":["0387-5911","1884-569X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Japanese Association for Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/kansenshogakuzasshi1970/58/12/58_12_1289/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110331314","display_name":"Masao Tamura","orcid":"https://orcid.org/0000-0002-1560-7441","observed_orcids":["https://orcid.org/0000-0002-1560-7441"]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masao TAMURA","raw_affiliation_strings":["\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I180680657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100714786","display_name":"Takashi Ito","orcid":"https://orcid.org/0000-0003-1740-3992","observed_orcids":["https://orcid.org/0000-0003-1740-3992"]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi ITO","raw_affiliation_strings":["\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I180680657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109858433","display_name":"Morio SUDO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Morio SUDO","raw_affiliation_strings":["\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I180680657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060327109","display_name":"Minoru Tazawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Minoru TAZAWA","raw_affiliation_strings":["\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I180680657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035531411","display_name":"Tsuneo Sayama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tsuneo SAYAMA","raw_affiliation_strings":["\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I180680657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004747141","display_name":"Masami Yoshida","orcid":"https://orcid.org/0000-0002-1099-8367","observed_orcids":["https://orcid.org/0000-0002-1099-8367"]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masami YOSHIDA","raw_affiliation_strings":["\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I180680657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108105246","display_name":"Ayako Suzuki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405284722","display_name":"Akita Rosai Hospital","ror":"https://ror.org/043mcyg59","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210135681","https://openalex.org/I4405284722"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ayako SUZUKI","raw_affiliation_strings":["\u79cb\u7530\u52b4\u707d\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u79cb\u7530\u52b4\u707d\u75c5\u9662\u5185\u79d1","institution_ids":["https://openalex.org/I4405284722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022303121","display_name":"Masao Sato","orcid":"https://orcid.org/0000-0003-1690-9000","observed_orcids":["https://orcid.org/0000-0003-1690-9000"]},"institutions":[{"id":"https://openalex.org/I4405255307","display_name":"Iwate Prefectural Ofunato Hospital","ror":"https://ror.org/02vje2a46","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405255307"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masao SATO","raw_affiliation_strings":["\u5ca9\u624b\u770c\u7acb\u5927\u8239\u6e21\u75c5\u9662\u7b2c2\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u770c\u7acb\u5927\u8239\u6e21\u75c5\u9662\u7b2c2\u5185\u79d1","institution_ids":["https://openalex.org/I4405255307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110336446","display_name":"Takehisa MURAKAMI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210096923","display_name":"Fukuoka Hospital","ror":"https://ror.org/00vv7qz60","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096923","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takehisa MURAKAMI","raw_affiliation_strings":["\u5ca9\u624b\u770c\u7acb\u798f\u5ca1\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u770c\u7acb\u798f\u5ca1\u75c5\u9662\u5185\u79d1","institution_ids":["https://openalex.org/I4210096923"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108595132","display_name":"Shinya MIYAMOTO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210096923","display_name":"Fukuoka Hospital","ror":"https://ror.org/00vv7qz60","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096923","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinya MIYAMOTO","raw_affiliation_strings":["\u5ca9\u624b\u770c\u7acb\u798f\u5ca1\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5ca9\u624b\u770c\u7acb\u798f\u5ca1\u75c5\u9662\u5185\u79d1","institution_ids":["https://openalex.org/I4210096923"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075233035","display_name":"Hiroshi End\u00f4","orcid":"https://orcid.org/0000-0003-1940-4171","observed_orcids":["https://orcid.org/0000-0003-1940-4171"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroshi ENDO","raw_affiliation_strings":["\u9060\u85e4\u5185\u79d1\u80c3\u8178\u79d1\u533b\u9662"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u9060\u85e4\u5185\u79d1\u80c3\u8178\u79d1\u533b\u9662","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057897528","display_name":"Nobuhisa SATO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nobuhisa SATO","raw_affiliation_strings":["\u6cb3\u5357\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6cb3\u5357\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071238972","display_name":"Hiroshi KURAMITSU","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroshi KURAMITSU","raw_affiliation_strings":["\u5317\u4e0a\u6e08\u751f\u4f1a\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5317\u4e0a\u6e08\u751f\u4f1a\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016091762","display_name":"Katsuyoshi MORIYA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katsuyoshi MORIYA","raw_affiliation_strings":["\u5317\u4e0a\u6e08\u751f\u4f1a\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5317\u4e0a\u6e08\u751f\u4f1a\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057486147","display_name":"Kazutoshi GOMI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazutoshi GOMI","raw_affiliation_strings":["\u5317\u4e0a\u6e08\u751f\u4f1a\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5317\u4e0a\u6e08\u751f\u4f1a\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111582977","display_name":"Ikuo Sato","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ikuo SATO","raw_affiliation_strings":["\u753a\u7acb\u845b\u5dfb\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u753a\u7acb\u845b\u5dfb\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080981474","display_name":"Kazumichi MIYA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazumichi MIYA","raw_affiliation_strings":["\u753a\u7acb\u845b\u5dfb\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u753a\u7acb\u845b\u5dfb\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113663916","display_name":"Hisaaki HOSOKAWA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hisaaki HOSOKAWA","raw_affiliation_strings":["\u4e09\u611b\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u4e09\u611b\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110410996","display_name":"Hidemitsu MORI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hidemitsu MORI","raw_affiliation_strings":["\u4e09\u611b\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u4e09\u611b\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067035983","display_name":"S Mitsui","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shotaro MITSUI","raw_affiliation_strings":["\u6edd\u6ca2\u4e2d\u592e\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6edd\u6ca2\u4e2d\u592e\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110769186","display_name":"Kenichi Takeuchi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kenichi TAKEUCHI","raw_affiliation_strings":["\u6edd\u6ca2\u4e2d\u592e\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6edd\u6ca2\u4e2d\u592e\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112169458","display_name":"Kazuji MIKAMI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazuji MIKAMI","raw_affiliation_strings":["\u6edd\u6ca2\u4e2d\u592e\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6edd\u6ca2\u4e2d\u592e\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097726720","display_name":"Hisashi TOGASAWA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hisashi TOGASAWA","raw_affiliation_strings":["\u6597\u30b1\u6ca2\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6597\u30b1\u6ca2\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kunio SUZUKI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210102350","display_name":"Jyoban Hospital of Tokiwa Foundation","ror":"https://ror.org/00njwz164","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210102350"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kunio SUZUKI","raw_affiliation_strings":["\u5e38\u78d0\u533b\u9662"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5e38\u78d0\u533b\u9662","institution_ids":["https://openalex.org/I4210102350"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yasuyuki NISHIJIMA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuyuki NISHIJIMA","raw_affiliation_strings":["\u897f\u5cf6\u533b\u9662"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u897f\u5cf6\u533b\u9662","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102232324","display_name":"Syunichi KITAZAWA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285328","display_name":"Hachinohe Red Cross Hospital","ror":"https://ror.org/057dfef86","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4405285328"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Syunichi KITAZAWA","raw_affiliation_strings":["\u516b\u6238\u8d64\u5341\u5b57\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u516b\u6238\u8d64\u5341\u5b57\u75c5\u9662\u5185\u79d1","institution_ids":["https://openalex.org/I4405285328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033539324","display_name":"Kazuo TANIFUJI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285328","display_name":"Hachinohe Red Cross Hospital","ror":"https://ror.org/057dfef86","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4405285328"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuo TANIFUJI","raw_affiliation_strings":["\u516b\u6238\u8d64\u5341\u5b57\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u516b\u6238\u8d64\u5341\u5b57\u75c5\u9662\u5185\u79d1","institution_ids":["https://openalex.org/I4405285328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110410997","display_name":"Takeshi BANDO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285204","display_name":"Morioka Red Cross Hospital","ror":"https://ror.org/04zxfy670","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4405285204"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeshi BANDO","raw_affiliation_strings":["\u76db\u5ca1\u8d64\u5341\u5b57\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u76db\u5ca1\u8d64\u5341\u5b57\u75c5\u9662\u5185\u79d1","institution_ids":["https://openalex.org/I4405285204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102232325","display_name":"Kiichi YAMAZAKI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kiichi YAMAZAKI","raw_affiliation_strings":["\u5c71\u5d0e\u5185\u79d1\u533b\u9662"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5c71\u5d0e\u5185\u79d1\u533b\u9662","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040485100","display_name":"T Shimoda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Terukazu SHIMODA","raw_affiliation_strings":["\u516c\u7acb\u6a2a\u624b\u75c5\u9662\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u516c\u7acb\u6a2a\u624b\u75c5\u9662\u5185\u79d1","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026194201","display_name":"Toru Yoshida","orcid":"https://orcid.org/0000-0002-1384-2210","observed_orcids":["https://orcid.org/0000-0002-1384-2210"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toru YOSHIDA","raw_affiliation_strings":["\u5409\u7530\u5185\u79d1\u533b\u9662"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5409\u7530\u5185\u79d1\u533b\u9662","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051239054","display_name":"Eiji Wakayama","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eiji WAKAYAMA","raw_affiliation_strings":["\u82e5\u5c71\u5185\u79d1\u533b\u9662"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u82e5\u5c71\u5185\u79d1\u533b\u9662","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110331014","display_name":"Kazunobu Sugawara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I112524849","display_name":"Yamagata University","ror":"https://ror.org/00xy44n04","country_code":"JP","type":"education","lineage":["https://openalex.org/I112524849"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazunobu SUGAWARA","raw_affiliation_strings":["\u5c71\u5f62\u5927\u5b66\u533b\u5b66\u90e8\u4ed8\u5c5e\u75c5\u9662\u85ac\u5264\u90e8"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u5c71\u5f62\u5927\u5b66\u533b\u5b66\u90e8\u4ed8\u5c5e\u75c5\u9662\u85ac\u5264\u90e8","institution_ids":["https://openalex.org/I112524849"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.29643869,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"58","issue":"12","first_page":"1289","last_page":"1304"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.295199990272522,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.295199990272522,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13770","display_name":"Pediatric health and respiratory diseases","score":0.13940000534057617,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.05040000006556511,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flurbiprofen","display_name":"flurbiprofen","score":1.0},{"id":"https://openalex.org/keywords/ibuprofen","display_name":"ibuprofen","score":1.0},{"id":"https://openalex.org/keywords/nonsteroidal-anti-inflammatory-drugs","display_name":"nonsteroidal anti-inflammatory drugs","score":0.9300000071525574},{"id":"https://openalex.org/keywords/analgesic-efficacy","display_name":"analgesic efficacy","score":0.7929999828338623},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.7170000076293945},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.6769999861717224},{"id":"https://openalex.org/keywords/symptom-improvement","display_name":"symptom improvement","score":0.41499999165534973},{"id":"https://openalex.org/keywords/hoarseness","display_name":"hoarseness","score":0.7039999961853027},{"id":"https://openalex.org/keywords/muscle-and-joint-pain","display_name":"muscle and joint pain","score":0.7519999742507935}],"concepts":[{"id":"https://openalex.org/C2781000538","wikidata":"https://www.wikidata.org/wiki/Q419890","display_name":"Flurbiprofen","level":2,"score":0.9951027035713196},{"id":"https://openalex.org/C2779944601","wikidata":"https://www.wikidata.org/wiki/Q186969","display_name":"Ibuprofen","level":2,"score":0.9062407612800598},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7131316661834717},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5881556272506714},{"id":"https://openalex.org/C2779644171","wikidata":"https://www.wikidata.org/wiki/Q13400765","display_name":"Respiratory tract","level":3,"score":0.5666221380233765},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.4838949143886566},{"id":"https://openalex.org/C2780820201","wikidata":"https://www.wikidata.org/wiki/Q173235","display_name":"Analgesic","level":2,"score":0.44308382272720337},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.38237521052360535},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3147665560245514},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.277743399143219}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005480","descriptor_name":"Flurbiprofen","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007052","descriptor_name":"Ibuprofen","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011422","descriptor_name":"Propionates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012141","descriptor_name":"Respiratory Tract Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.11150/kansenshogakuzasshi1970.58.1289","doi":"https://doi.org/10.11150/kansenshogakuzasshi1970.58.1289","is_oa":true,"landing_page_url":"https://doi.org/10.11150/kansenshogakuzasshi1970.58.1289","pdf_url":"https://www.jstage.jst.go.jp/article/kansenshogakuzasshi1970/58/12/58_12_1289/_pdf","source":{"id":"https://openalex.org/S4210176383","display_name":"Kansenshogaku zasshi","issn_l":"0387-5911","issn":["0387-5911","1884-569X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Japanese Association for Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:6442724","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6442724","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","raw_type":"Clinical Trial"}],"best_oa_location":{"id":"doi:10.11150/kansenshogakuzasshi1970.58.1289","doi":"https://doi.org/10.11150/kansenshogakuzasshi1970.58.1289","is_oa":true,"landing_page_url":"https://doi.org/10.11150/kansenshogakuzasshi1970.58.1289","pdf_url":"https://www.jstage.jst.go.jp/article/kansenshogakuzasshi1970/58/12/58_12_1289/_pdf","source":{"id":"https://openalex.org/S4210176383","display_name":"Kansenshogaku zasshi","issn_l":"0387-5911","issn":["0387-5911","1884-569X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Japanese Association for Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2419047331.pdf","grobid_xml":"https://content.openalex.org/works/W2419047331.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2129007006","https://openalex.org/W2406461632","https://openalex.org/W2467418143","https://openalex.org/W2334243291","https://openalex.org/W2339703965","https://openalex.org/W2329373242","https://openalex.org/W2411796835","https://openalex.org/W1981616944","https://openalex.org/W4407845937","https://openalex.org/W2411890127"],"abstract_inverted_index":{"The":[0,27,75,105],"efficacy":[1,191],"and":[2,44,102,114,120,140,187,192],"safety":[3,193],"of":[4,12,62,77,84,97,107,156,194],"non-steroidal":[5],"analgesic/anti-inflammatory":[6],"agent,":[7],"Flurbiprofen":[8,38,68,111,138,162,173,195],"were":[9,29,65,159,196],"compared":[10],"those":[11],"Ibuprofen":[13,48,72,91,118,144,165],"in":[14,36,46,67,87,94,110,116,136,142,161],"patients":[15],"with":[16],"acute":[17,182],"upper":[18,183],"respiratory":[19,184],"tract":[20,185],"inflammation":[21,186],"by":[22],"a":[23,175],"double":[24],"blind":[25],"method.":[26],"result":[28],"as":[30],"follows:1.":[31],"Final":[32],"glocal":[33],"improvement":[34,64],"rate":[35],"the":[37,47,60,78,85,95,117,137,143,154,179,189],"group":[39,49,69,73,89,139,163],"(120":[40],"mg/day)":[41],"was":[42,80,112,122,134],"59.2%":[43],"59.3%":[45],"(600":[50],"mg/day),":[51],"showing":[52,146],"no":[53,123,147],"significant":[54,148],"difference":[55,125,149],"between":[56,126,150],"two":[57,127,151],"groups.":[58,152],"However,":[59,153],"cases":[61],"excellent":[63,157],"more":[66,160],"(18.4%)":[70],"than":[71,90,164,199],"(14.8%).2.":[74],"development":[76],"effect":[79],"early":[81],"after":[82],"administration":[83],"drug":[86,177],"flurbiprofen":[88],"group,":[92,119,145],"especially":[93],"symptoms":[96],"muscle":[98],"pain,":[99],"joint":[100],"pain":[101],"hoaseness":[103],"(p<0.05).3.":[104],"incidence":[106],"side":[108],"effects":[109],"5.1%":[113],"2.4%":[115],"there":[121],"signicant":[124],"groups.4.":[128],"In":[129],"global":[130],"utility":[131],"rate,":[132],"usefulness":[133,158],"60.0%":[135],"61.2%":[141],"case":[155],"group.From":[166],"these":[167],"result,":[168],"it":[169],"is":[170,174],"concluded":[171],"that":[172,188],"useful":[176],"for":[178],"treatment":[180],"on":[181],"clinical":[190],"slightly":[197],"better":[198],"Ibuprofen.":[200]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}