{"id":"https://openalex.org/W2417499198","doi":"https://doi.org/10.2310/7290.2007.00011","title":"Forebrain Ischemia-Reperfusion Simulating Cardiac Arrest in Mice Induces Edema and DNA Fragmentation in the Brain","display_name":"Forebrain Ischemia-Reperfusion Simulating Cardiac Arrest in Mice Induces Edema and DNA Fragmentation in the Brain","publication_year":2007,"publication_date":"2007-05-01","ids":{"openalex":"https://openalex.org/W2417499198","doi":"https://doi.org/10.2310/7290.2007.00011","mag":"2417499198","pmid":"https://pubmed.ncbi.nlm.nih.gov/17532882","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2644455"},"language":"en","primary_location":{"id":"doi:10.2310/7290.2007.00011","doi":"https://doi.org/10.2310/7290.2007.00011","is_oa":true,"landing_page_url":"https://doi.org/10.2310/7290.2007.00011","pdf_url":null,"source":{"id":"https://openalex.org/S55147621","display_name":"Molecular Imaging","issn_l":"1535-3508","issn":["1535-3508","1536-0121"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Imaging","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.2310/7290.2007.00011","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009098155","display_name":"Christina H. Liu","orcid":"https://orcid.org/0000-0002-5723-177X","observed_orcids":["https://orcid.org/0000-0002-5723-177X"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christina H. Liu","raw_affiliation_strings":["From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210092658","https://openalex.org/I4210127055","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108574099","display_name":"Shuning Huang","orcid":"https://orcid.org/0000-0002-5827-2960","observed_orcids":["https://orcid.org/0000-0002-5827-2960"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shuning Huang","raw_affiliation_strings":["From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210092658","https://openalex.org/I4210127055","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027821781","display_name":"Young Ro Kim","orcid":"https://orcid.org/0000-0002-2924-5621","observed_orcids":["https://orcid.org/0000-0002-2924-5621"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Young R. Kim","raw_affiliation_strings":["From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210092658","https://openalex.org/I4210127055","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004268054","display_name":"Bruce Robert Rosen","orcid":"https://orcid.org/0000-0002-8576-0839","observed_orcids":["https://orcid.org/0000-0002-8576-0839"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce R. Rosen","raw_affiliation_strings":["From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210092658","https://openalex.org/I4210127055","https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079146491","display_name":"Philip K. Liu","orcid":"https://orcid.org/0000-0003-2149-3564","observed_orcids":["https://orcid.org/0000-0003-2149-3564"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Philip K. Liu","raw_affiliation_strings":["From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA","From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA","Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA; the Transcript Imaging and NeuroRepair Laboratory, Department of Radiology, Massachusetts General Hospital Charlestown, MA; and Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210092658","https://openalex.org/I4210127055","https://openalex.org/I63966007"]},{"raw_affiliation_string":"From the A.A. Martinos Center for Biomedical Imaging Charlestown, MA","institution_ids":["https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA","institution_ids":["https://openalex.org/I4210092658"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5079146491"],"corresponding_institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210092658","https://openalex.org/I4210127055","https://openalex.org/I63966007"],"apc_list":{"value":2175,"currency":"USD","value_usd":2175},"apc_paid":{"value":2175,"currency":"USD","value_usd":2175},"fwci":2.1314,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.86500331,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":"3","first_page":"156","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.6395999789237976,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.6395999789237976,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10645","display_name":"Cardiac Arrest and Resuscitation","score":0.19429999589920044,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.055399999022483826,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiac-arrest","display_name":"cardiac arrest","score":0.9269999861717224},{"id":"https://openalex.org/keywords/cerebral-edema","display_name":"cerebral edema","score":0.7409999966621399},{"id":"https://openalex.org/keywords/dna-fragmentation","display_name":"DNA fragmentation","score":0.9599999785423279},{"id":"https://openalex.org/keywords/bilateral-common-carotid-artery-occlusion","display_name":"bilateral common carotid artery occlusion","score":0.8050000071525574},{"id":"https://openalex.org/keywords/superparamagnetic-iron-oxide-nanoparticles","display_name":"superparamagnetic iron oxide nanoparticles","score":0.7950000166893005},{"id":"https://openalex.org/keywords/t2-weighted-mri","display_name":"T2-weighted MRI","score":0.7829999923706055},{"id":"https://openalex.org/keywords/in-vivo-neuroimaging","display_name":"in vivo brain imaging","score":0.5789999961853027},{"id":"https://openalex.org/keywords/hippocampal-neuronal-death","display_name":"hippocampal neuronal death","score":0.8429999947547913},{"id":"https://openalex.org/keywords/diffusion-weighted-imaging","display_name":"diffusion-weighted imaging","score":0.781000018119812},{"id":"https://openalex.org/keywords/c-fos-mrna","display_name":"c-fos mRNA","score":0.4410000145435333},{"id":"https://openalex.org/keywords/brain-injury-detection","display_name":"brain injury detection","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.6619277596473694},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5072764754295349},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5059501528739929},{"id":"https://openalex.org/C2779246727","wikidata":"https://www.wikidata.org/wiki/Q184215","display_name":"Thalamus","level":2,"score":0.488471657037735},{"id":"https://openalex.org/C2780114680","wikidata":"https://www.wikidata.org/wiki/Q1413991","display_name":"Reperfusion injury","level":3,"score":0.46452105045318604},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.4608874022960663},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.4430285096168518},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4316723942756653},{"id":"https://openalex.org/C2780886150","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Edema","level":2,"score":0.4280863106250763},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3813619911670685},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.33876293897628784},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2469424307346344},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.15731489658355713},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D001929","descriptor_name":"Brain Edema","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001929","descriptor_name":"Brain Edema","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D006323","descriptor_name":"Heart Arrest","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010087","descriptor_name":"Oxides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015427","descriptor_name":"Reperfusion Injury","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D016548","descriptor_name":"Prosencephalon","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D016760","descriptor_name":"Proto-Oncogene Proteins c-fos","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053758","descriptor_name":"Nanoparticles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053938","descriptor_name":"DNA Fragmentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.2310/7290.2007.00011","doi":"https://doi.org/10.2310/7290.2007.00011","is_oa":true,"landing_page_url":"https://doi.org/10.2310/7290.2007.00011","pdf_url":null,"source":{"id":"https://openalex.org/S55147621","display_name":"Molecular Imaging","issn_l":"1535-3508","issn":["1535-3508","1536-0121"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Imaging","raw_type":"journal-article"},{"id":"pmid:17532882","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17532882","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular imaging","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2644455","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2644455","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Mol Imaging","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:2d1dd6486c6f4632aaaf067de6cd52cf","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/2d1dd6486c6f4632aaaf067de6cd52cf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Imaging, Vol 6 (2007)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.2310/7290.2007.00011","doi":"https://doi.org/10.2310/7290.2007.00011","is_oa":true,"landing_page_url":"https://doi.org/10.2310/7290.2007.00011","pdf_url":null,"source":{"id":"https://openalex.org/S55147621","display_name":"Molecular Imaging","issn_l":"1535-3508","issn":["1535-3508","1536-0121"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1815946096","display_name":null,"funder_award_id":"T32-EB001680","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G3068945569","display_name":"Neurovascular Mechanisns of Brain Function and Disease","funder_award_id":"R21NS057556","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5615517985","display_name":"Center for Functional Imaging Technologies","funder_award_id":"P41RR014075","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G7280599525","display_name":"Gene Repair in signal Transduction after CNS Injury","funder_award_id":"R01NS045845","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000863871","display_name":"Neuroimaging Training Program","funder_award_id":"2t32eb001680-21","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W337913160","https://openalex.org/W1541118450","https://openalex.org/W1572374534","https://openalex.org/W1584693150","https://openalex.org/W1670264433","https://openalex.org/W1790510139","https://openalex.org/W1963898168","https://openalex.org/W1969974084","https://openalex.org/W1970101659","https://openalex.org/W1971686124","https://openalex.org/W1973775059","https://openalex.org/W1976943872","https://openalex.org/W1981808235","https://openalex.org/W1984055074","https://openalex.org/W1995432809","https://openalex.org/W1998005675","https://openalex.org/W2002412570","https://openalex.org/W2007036953","https://openalex.org/W2009057645","https://openalex.org/W2009505064","https://openalex.org/W2012218937","https://openalex.org/W2012783173","https://openalex.org/W2020980253","https://openalex.org/W2021467812","https://openalex.org/W2024868951","https://openalex.org/W2033557120","https://openalex.org/W2038473458","https://openalex.org/W2038958259","https://openalex.org/W2039867462","https://openalex.org/W2041486005","https://openalex.org/W2043351461","https://openalex.org/W2055796980","https://openalex.org/W2063679775","https://openalex.org/W2067193940","https://openalex.org/W2074566560","https://openalex.org/W2074916428","https://openalex.org/W2080278967","https://openalex.org/W2084627999","https://openalex.org/W2086337334","https://openalex.org/W2086535395","https://openalex.org/W2093718909","https://openalex.org/W2094316306","https://openalex.org/W2094814297","https://openalex.org/W2100380391","https://openalex.org/W2102238490","https://openalex.org/W2114798577","https://openalex.org/W2122836762","https://openalex.org/W2127428391","https://openalex.org/W2132799139","https://openalex.org/W2136848562","https://openalex.org/W2137837999","https://openalex.org/W2143780659","https://openalex.org/W2144918294","https://openalex.org/W2155885439","https://openalex.org/W2156117604","https://openalex.org/W2156253520","https://openalex.org/W2158354886","https://openalex.org/W2163109099","https://openalex.org/W2164324123","https://openalex.org/W2166615294","https://openalex.org/W2410350671"],"related_works":["https://openalex.org/W2991164770","https://openalex.org/W2109106699","https://openalex.org/W158106257","https://openalex.org/W3186976539","https://openalex.org/W2035882067","https://openalex.org/W7203826080","https://openalex.org/W1981775620","https://openalex.org/W2389013825","https://openalex.org/W2991433680","https://openalex.org/W4398179967"],"abstract_inverted_index":{"Brain":[0],"injury":[1,23,194],"affects":[2],"one-third":[3],"of":[4,14,40,65,70,76],"persons":[5],"who":[6],"survive":[7],"after":[8,67],"heart":[9,36],"attack,":[10],"even":[11],"with":[12,170],"restoration":[13,39],"spontaneous":[15],"circulation":[16],"by":[17,34,196],"cardiopulmonary":[18],"resuscitation.":[19],"We":[20,61,165],"studied":[21],"brain":[22,193],"resulting":[24],"from":[25],"transient":[26,68],"bilateral":[27],"carotid":[28],"artery":[29],"occlusion":[30],"(BCAO)":[31],"and":[32,38,59,73,91,173,184],"reperfusion":[33,175],"simulating":[35],"attack":[37],"circulation,":[41],"respectively,":[42],"in":[43,55,79,87,95,108,134,144,181,202],"live":[44,109,203],"C57Black6":[45],"mice.":[46],"This":[47],"model":[48],"is":[49],"known":[50],"to":[51,102,128,136],"induce":[52],"neuronal":[53],"death":[54],"the":[56,63,88,96,103,182],"hippocampus,":[57],"striatum,":[58,89],"cortex.":[60],"report":[62],"appearance":[64],"edema":[66],"BCAO":[69,172],"60":[71],"minutes":[72],"1":[74],"day":[75],"reperfusion.":[77],"Hyperintensity":[78],"diffusion-weighted":[80],"magnetic":[81,116],"resonance":[82,117],"imaging":[83],"(MRI)":[84],"was":[85,126,153],"detectable":[86],"thalamus,":[90],"cortex":[92,185],"but":[93],"not":[94],"hippocampus.":[97],"To":[98],"determine":[99],"whether":[100],"damage":[101],"hippocampus":[104,183],"can":[105,199],"be":[106,200],"detected":[107,201],"animals,":[110],"we":[111,142],"infused":[112],"a":[113],"T(2)":[114],"susceptibility":[115],"contrast":[118],"agent":[119],"(superparamagnetic":[120],"iron":[121],"oxide":[122],"nanoparticles":[123],"[SPIONs])":[124],"that":[125,167,192],"linked":[127],"single-stranded":[129],"deoxyribonucleic":[130],"acid":[131,140],"(DNA)":[132],"complementary":[133],"sequence":[135],"c-fos":[137],"messenger":[138],"ribonucleic":[139],"(SPION-cfos);":[141],"acquired":[143],"vivo":[145],"T(2)*-weighted":[146],"MRI":[147],"3":[148],"days":[149],"later.":[150],"SPION":[151,179],"retention":[152,180],"measured":[154],"as":[155],"T(2)*":[156],"(milliseconds)":[157],"signal":[158],"reduction":[159],"or":[160],"R(2)*":[161],"value":[162],"(s(-1))":[163],"elevation.":[164],"found":[166],"animals":[168],"treated":[169],"60-minute":[171],"7-day":[174],"exhibited":[176],"significantly":[177],"less":[178],"than":[186],"sham-operated":[187],"animals.":[188,204],"These":[189],"findings":[190],"suggest":[191],"induced":[195],"cardiac":[197],"arrest":[198]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}
