{"id":"https://openalex.org/W2417310706","doi":"https://doi.org/10.1016/j.biomaterials.2016.06.012","title":"A comprehensive review on droplet-based bioprinting: Past, present and future","display_name":"A comprehensive review on droplet-based bioprinting: Past, present and future","publication_year":2016,"publication_date":"2016-06-07","ids":{"openalex":"https://openalex.org/W2417310706","doi":"https://doi.org/10.1016/j.biomaterials.2016.06.012","mag":"2417310706","pmid":"https://pubmed.ncbi.nlm.nih.gov/27318933"},"language":"en","primary_location":{"id":"doi:10.1016/j.biomaterials.2016.06.012","doi":"https://doi.org/10.1016/j.biomaterials.2016.06.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2016.06.012","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.biomaterials.2016.06.012","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058213775","display_name":"Hemanth Gudapati","orcid":"https://orcid.org/0000-0001-9610-8873","observed_orcids":["https://orcid.org/0000-0001-9610-8873"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hemanth Gudapati","raw_affiliation_strings":["Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA; The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA","Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA","The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA; The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053656544","display_name":"Madhuri Dey","orcid":"https://orcid.org/0000-0002-9523-8083","observed_orcids":["https://orcid.org/0000-0002-9523-8083"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Madhuri Dey","raw_affiliation_strings":["Department of Chemistry, Penn State University, University Park, PA 16802, USA; The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA","Department of Chemistry, Penn State University, University Park, PA 16802, USA","The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Penn State University, University Park, PA 16802, USA; The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Chemistry, Penn State University, University Park, PA 16802, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083046197","display_name":"Ibrahim Tarik Ozbolat","orcid":"https://orcid.org/0000-0001-8328-4528","observed_orcids":["https://orcid.org/0000-0001-8328-4528"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ibrahim Ozbolat","raw_affiliation_strings":["Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA; The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA. Electronic address: ito1@psu.edu","Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA","The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA; The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA. Electronic address: ito1@psu.edu","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"The Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, USA","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5083046197"],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":5.2151,"has_fulltext":false,"cited_by_count":867,"citation_normalized_percentile":{"value":0.97971014,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"102","issue":null,"first_page":"20","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11523","display_name":"Nanomaterials and Printing Technologies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inkjet-bioprinting","display_name":"inkjet bioprinting","score":0.9390000104904175},{"id":"https://openalex.org/keywords/bioinks","display_name":"bioinks","score":0.8870000243186951},{"id":"https://openalex.org/keywords/bioprinters","display_name":"bioprinters","score":0.8830000162124634},{"id":"https://openalex.org/keywords/tissue-engineering","display_name":"tissue engineering","score":0.7620000243186951},{"id":"https://openalex.org/keywords/regenerative-medicine","display_name":"regenerative medicine","score":0.9909999966621399},{"id":"https://openalex.org/keywords/vascularization","display_name":"vascularization","score":0.8610000014305115},{"id":"https://openalex.org/keywords/porosity","display_name":"porosity","score":0.8050000071525574},{"id":"https://openalex.org/keywords/high-throughput-screening","display_name":"high-throughput screening","score":0.7919999957084656},{"id":"https://openalex.org/keywords/cancer-research","display_name":"cancer research","score":0.6370000243186951},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C2779718196","wikidata":"https://www.wikidata.org/wiki/Q17018741","display_name":"3D bioprinting","level":3,"score":0.762432336807251},{"id":"https://openalex.org/C2780609957","wikidata":"https://www.wikidata.org/wiki/Q108887885","display_name":"Biofabrication","level":3,"score":0.6479224562644958},{"id":"https://openalex.org/C10854531","wikidata":"https://www.wikidata.org/wiki/Q1061415","display_name":"Regenerative medicine","level":3,"score":0.6466153860092163},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.513235330581665},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.4115293025970459},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3872869908809662},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.36840611696243286},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.35692307353019714},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33164462447166443},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.257854163646698},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.2558724284172058},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.12286853790283203},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044968","descriptor_name":"Regenerative Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062028","descriptor_name":"Bioprinting","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D062028","descriptor_name":"Bioprinting","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.biomaterials.2016.06.012","doi":"https://doi.org/10.1016/j.biomaterials.2016.06.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2016.06.012","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials","raw_type":"journal-article"},{"id":"pmid:27318933","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27318933","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.biomaterials.2016.06.012","doi":"https://doi.org/10.1016/j.biomaterials.2016.06.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2016.06.012","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2879860839","display_name":"CAREER: Hybrid Bioprinting of Engineered Vascularized Endocrine Tissues","funder_award_id":"1349716","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7709473466","display_name":"Bioprinting of Bone Tissue into Defect Sites on Animal Models in Surgery Settings","funder_award_id":"1462232","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":170,"referenced_works":["https://openalex.org/W33869457","https://openalex.org/W1481145212","https://openalex.org/W1517550653","https://openalex.org/W1554084968","https://openalex.org/W1739944755","https://openalex.org/W1881445774","https://openalex.org/W1963613524","https://openalex.org/W1964276588","https://openalex.org/W1967696528","https://openalex.org/W1968013773","https://openalex.org/W1969936574","https://openalex.org/W1972047296","https://openalex.org/W1972822322","https://openalex.org/W1973622948","https://openalex.org/W1975245619","https://openalex.org/W1976091266","https://openalex.org/W1976411029","https://openalex.org/W1976842528","https://openalex.org/W1977564234","https://openalex.org/W1979079389","https://openalex.org/W1979891646","https://openalex.org/W1980730283","https://openalex.org/W1981317628","https://openalex.org/W1981779415","https://openalex.org/W1982043414","https://openalex.org/W1982397697","https://openalex.org/W1985133253","https://openalex.org/W1990424776","https://openalex.org/W1990613538","https://openalex.org/W1990629503","https://openalex.org/W1991073285","https://openalex.org/W1991914157","https://openalex.org/W1993347357","https://openalex.org/W1994903148","https://openalex.org/W1995745186","https://openalex.org/W1996897600","https://openalex.org/W2001662737","https://openalex.org/W2002174197","https://openalex.org/W2003576847","https://openalex.org/W2003728131","https://openalex.org/W2004669045","https://openalex.org/W2005242898","https://openalex.org/W2007003459","https://openalex.org/W2010294852","https://openalex.org/W2011808587","https://openalex.org/W2011976306","https://openalex.org/W2014063246","https://openalex.org/W2014482422","https://openalex.org/W2019492166","https://openalex.org/W2020921921","https://openalex.org/W2021482259","https://openalex.org/W2021765524","https://openalex.org/W2023913887","https://openalex.org/W2023968193","https://openalex.org/W2026864439","https://openalex.org/W2027197191","https://openalex.org/W2027885271","https://openalex.org/W2028699424","https://openalex.org/W2029319007","https://openalex.org/W2029489857","https://openalex.org/W2030932194","https://openalex.org/W2031596741","https://openalex.org/W2039710683","https://openalex.org/W2040984241","https://openalex.org/W2041920957","https://openalex.org/W2044855501","https://openalex.org/W2045037817","https://openalex.org/W2045047041","https://openalex.org/W2045852090","https://openalex.org/W2047961352","https://openalex.org/W2048071051","https://openalex.org/W2048320223","https://openalex.org/W2048644480","https://openalex.org/W2050076318","https://openalex.org/W2054995347","https://openalex.org/W2056177992","https://openalex.org/W2056416320","https://openalex.org/W2057375560","https://openalex.org/W2057966022","https://openalex.org/W2060204215","https://openalex.org/W2061796957","https://openalex.org/W2062521268","https://openalex.org/W2064256800","https://openalex.org/W2064307011","https://openalex.org/W2066612010","https://openalex.org/W2067021065","https://openalex.org/W2067424338","https://openalex.org/W2067497888","https://openalex.org/W2069520190","https://openalex.org/W2071033251","https://openalex.org/W2072607005","https://openalex.org/W2072834332","https://openalex.org/W2073088169","https://openalex.org/W2075814690","https://openalex.org/W2076364875","https://openalex.org/W2078420114","https://openalex.org/W2080034453","https://openalex.org/W2080500213","https://openalex.org/W2081517502","https://openalex.org/W2081851726","https://openalex.org/W2082955796","https://openalex.org/W2083396861","https://openalex.org/W2084261722","https://openalex.org/W2085667630","https://openalex.org/W2086762695","https://openalex.org/W2088200469","https://openalex.org/W2088990945","https://openalex.org/W2092882355","https://openalex.org/W2092884676","https://openalex.org/W2096261947","https://openalex.org/W2097154761","https://openalex.org/W2098594636","https://openalex.org/W2102327115","https://openalex.org/W2102954558","https://openalex.org/W2104480579","https://openalex.org/W2105559315","https://openalex.org/W2106130060","https://openalex.org/W2110507992","https://openalex.org/W2111061702","https://openalex.org/W2112226869","https://openalex.org/W2114416030","https://openalex.org/W2115609745","https://openalex.org/W2115728174","https://openalex.org/W2118614307","https://openalex.org/W2121907621","https://openalex.org/W2124838743","https://openalex.org/W2125370350","https://openalex.org/W2125795420","https://openalex.org/W2129322399","https://openalex.org/W2130119039","https://openalex.org/W2130171570","https://openalex.org/W2130475692","https://openalex.org/W2133683725","https://openalex.org/W2134208433","https://openalex.org/W2135529495","https://openalex.org/W2137802443","https://openalex.org/W2139421372","https://openalex.org/W2144156830","https://openalex.org/W2145378298","https://openalex.org/W2145630658","https://openalex.org/W2147303742","https://openalex.org/W2152319185","https://openalex.org/W2153885566","https://openalex.org/W2153927649","https://openalex.org/W2154330397","https://openalex.org/W2157329190","https://openalex.org/W2166568270","https://openalex.org/W2167434988","https://openalex.org/W2168272503","https://openalex.org/W2168290744","https://openalex.org/W2169004133","https://openalex.org/W2169265379","https://openalex.org/W2169376093","https://openalex.org/W2173417615","https://openalex.org/W2197557991","https://openalex.org/W2206726567","https://openalex.org/W2231439883","https://openalex.org/W2285365370","https://openalex.org/W2312491239","https://openalex.org/W2340849929","https://openalex.org/W2410614660","https://openalex.org/W2411101077","https://openalex.org/W2487187460","https://openalex.org/W3023878974","https://openalex.org/W4251077493","https://openalex.org/W4383825359","https://openalex.org/W6633031811","https://openalex.org/W6667341254","https://openalex.org/W6681777022","https://openalex.org/W6703924643"],"related_works":["https://openalex.org/W2550877522","https://openalex.org/W4409776038","https://openalex.org/W4387131669","https://openalex.org/W2588705450","https://openalex.org/W7154913987","https://openalex.org/W4413804318","https://openalex.org/W4402725582","https://openalex.org/W7213561704","https://openalex.org/W2568275076","https://openalex.org/W4388532140"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":68},{"year":2025,"cited_by_count":80},{"year":2024,"cited_by_count":100},{"year":2023,"cited_by_count":118},{"year":2022,"cited_by_count":116},{"year":2021,"cited_by_count":82},{"year":2020,"cited_by_count":85},{"year":2019,"cited_by_count":80},{"year":2018,"cited_by_count":70},{"year":2017,"cited_by_count":53},{"year":2016,"cited_by_count":13}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}