{"id":"https://openalex.org/W2416559983","doi":null,"title":"[Use of transcription-based amplification and enzyme immunoassay methods to investigate possible Chlamydia trachomatis infections in women with genital complaints].","display_name":"[Use of transcription-based amplification and enzyme immunoassay methods to investigate possible Chlamydia trachomatis infections in women with genital complaints].","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2416559983","mag":"2416559983","pmid":"https://pubmed.ncbi.nlm.nih.gov/12476764"},"language":"tr","primary_location":{"id":"pmid:12476764","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12476764","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mikrobiyoloji bulteni","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071166855","display_name":"Yunus Bulut","orcid":"https://orcid.org/0000-0003-1501-2525","observed_orcids":["https://orcid.org/0000-0003-1501-2525","https://orcid.org/0000-0002-0582-8240"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Yunus Bulut","raw_affiliation_strings":["In\u00f6n\u00fc Universitesi Tip Fak\u00fcltesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Malatya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"In\u00f6n\u00fc Universitesi Tip Fak\u00fcltesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Malatya","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079812558","display_name":"Beng\u00fcl Durmaz","orcid":"https://orcid.org/0000-0002-9093-7440","observed_orcids":["https://orcid.org/0000-0002-9093-7440"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Beng\u00fcl Durmaz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013592415","display_name":"R\u0131za Durmaz","orcid":"https://orcid.org/0000-0001-6561-778X","observed_orcids":["https://orcid.org/0000-0001-6561-778X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Riza Durmaz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5044174523","display_name":"Bar\u0131\u015f Otlu","orcid":"https://orcid.org/0000-0002-6220-0521","observed_orcids":["https://orcid.org/0000-0002-6220-0521"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bari\u015f Otlu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"36","issue":"1","first_page":"31","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chlamydia-trachomatis","display_name":"Chlamydia trachomatis","score":0.996999979019165},{"id":"https://openalex.org/keywords/genital-chlamydial-infection","display_name":"genital chlamydial infection","score":0.7919999957084656},{"id":"https://openalex.org/keywords/transcription-mediated-amplification","display_name":"transcription-mediated amplification","score":0.9200000166893005},{"id":"https://openalex.org/keywords/enzyme-immunoassay","display_name":"enzyme immunoassay","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.6990000009536743},{"id":"https://openalex.org/keywords/endocervical-swabs","display_name":"endocervical swabs","score":0.7950000166893005},{"id":"https://openalex.org/keywords/igg-and-igm-antibodies","display_name":"IgM and IgG antibodies","score":0.75}],"concepts":[{"id":"https://openalex.org/C2777391075","wikidata":"https://www.wikidata.org/wiki/Q131065","display_name":"Chlamydia trachomatis","level":2,"score":0.9350231885910034},{"id":"https://openalex.org/C2780420688","wikidata":"https://www.wikidata.org/wiki/Q759183","display_name":"Immunoassay","level":3,"score":0.8295261263847351},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.653716504573822},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.542614758014679},{"id":"https://openalex.org/C2777038808","wikidata":"https://www.wikidata.org/wiki/Q13474598","display_name":"Chlamydiaceae","level":3,"score":0.5161103010177612},{"id":"https://openalex.org/C2778651837","wikidata":"https://www.wikidata.org/wiki/Q5102716","display_name":"Chlamydiales","level":3,"score":0.501835823059082},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44740819931030273},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3914150595664978},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.37511032819747925},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2962490916252136}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002584","descriptor_name":"Cervix Uteri","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005831","descriptor_name":"Genital Diseases, Female","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D005831","descriptor_name":"Genital Diseases, Female","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005831","descriptor_name":"Genital Diseases, Female","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007075","descriptor_name":"Immunoglobulin M","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012329","descriptor_name":"RNA, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012335","descriptor_name":"RNA, Ribosomal","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014421","descriptor_name":"Turkey","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:12476764","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12476764","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mikrobiyoloji bulteni","raw_type":"Comparative Study"},{"id":"pmh:649b8ae8-4756-498c-af82-f87ae9470010","doi":null,"is_oa":false,"landing_page_url":"https://avesis.aybu.edu.tr/publication/details/649b8ae8-4756-498c-af82-f87ae9470010/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055213","display_name":"AYBU AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2416559983","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12476764","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7018101689","https://openalex.org/W2502783298","https://openalex.org/W2085185417","https://openalex.org/W2469918386","https://openalex.org/W2017559404","https://openalex.org/W2268048502","https://openalex.org/W2072161999","https://openalex.org/W1538776929","https://openalex.org/W2425970944","https://openalex.org/W2421637492"],"abstract_inverted_index":{"This":[0],"study":[1],"was":[2,151],"performed":[3],"to":[4,20,91,131],"determine":[5],"the":[6,13,22,32,59,76,117,132,135,166,175,183],"prevalence":[7],"of":[8,34,63,78,139,160,177],"Chlamydia":[9],"trachomatis":[10,37,40,67,180],"infections":[11],"in":[12,58,75],"female":[14],"patients":[15,118],"with":[16,170],"genital":[17,35,178],"complaints,":[18],"and":[19,27,43,52,69,108,114,127,137,147,158],"compare":[21],"transcription":[23],"mediated":[24],"amplification":[25,54],"assay":[26],"enzyme":[28,49],"immunoassay":[29,50],"methods":[30],"for":[31,94,98,102,106,111,124,174],"diagnosis":[33,176],"C.":[36,39,66,179],"infections.":[38],"(Ct)":[41],"antigens":[42],"ribosomal":[44],"RNAs":[45],"were":[46,72,89,121,143],"researched":[47],"by":[48,81,189],"(EIA)":[51],"transcription-mediated":[53],"(TMA)":[55],"assay,":[56],"respectively":[57],"endocervical":[60],"swab":[61],"samples":[62],"90":[64,85],"patients.":[65],"IgG":[68,113],"IgM":[70,107],"antibodies":[71],"also":[73],"screened":[74],"sera":[77],"these":[79],"subjects,":[80],"EIA":[82,162,171],"method.":[83],"Of":[84],"patients,":[86],"18":[87],"(20%)":[88],"found":[90,122],"be":[92,187],"positive":[93,123,167],"Ct-rRNA,":[95],"12":[96,104],"(13%)":[97,105],"Ct-antigen,":[99,125],"20":[100],"(22%)":[101],"IgG,":[103],"14":[109],"(16%)":[110],"both":[112],"IgM.":[115],"Among":[116],"11":[119],"(12%)":[120],"Ct-rRNA":[126],"Ct-IgM":[128],"antibodies.":[129],"According":[130],"TMA":[133,156],"results,":[134],"sensitivity":[136],"specificity":[138],"EIA-Ct":[140],"antigen":[141],"method":[142],"estimated":[144],"as":[145],"67%":[146],"100%,":[148],"respectively.":[149],"There":[150],"statistically":[152],"significant":[153],"difference":[154],"between":[155],"positivity":[157],"those":[159],"two":[161],"methods.":[163],"In":[164],"conclusion,":[165],"results":[168,185],"obtained":[169],"are":[172],"reliable":[173],"infections,":[181],"however":[182],"negative":[184],"should":[186],"confirmed":[188],"TMA.":[190]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}