{"id":"https://openalex.org/W2415415035","doi":null,"title":"Obesity and gonadal function of women.","display_name":"Obesity and gonadal function of women.","publication_year":2004,"publication_date":"2004-08-01","ids":{"openalex":"https://openalex.org/W2415415035","mag":"2415415035","pmid":"https://pubmed.ncbi.nlm.nih.gov/16444176"},"language":"en","primary_location":{"id":"pmid:16444176","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16444176","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric endocrinology reviews : PER","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086973330","display_name":"Evanthia Diamanti\u2010Kandarakis","orcid":"https://orcid.org/0000-0003-2063-7319","observed_orcids":["https://orcid.org/0000-0003-2063-7319"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Evanthia Diamanti-Kandarakis","raw_affiliation_strings":["First Dept. of Medical School in the University of Athens, Greece. akandara@otenet.gr","First Dept. of Medical School in the University of Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Dept. of Medical School in the University of Athens, Greece. akandara@otenet.gr","institution_ids":["https://openalex.org/I200777214"]},{"raw_affiliation_string":"First Dept. of Medical School in the University of Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073650594","display_name":"HELEN A. KANDARAKIS","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Helen A Kandarakis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4227,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65172155,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1 Suppl 3","issue":null,"first_page":"465","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9760000109672546},{"id":"https://openalex.org/keywords/female-reproduction","display_name":"female reproduction","score":0.9089999794960022},{"id":"https://openalex.org/keywords/gonadal-dysfunction","display_name":"gonadal dysfunction","score":0.8169999718666077},{"id":"https://openalex.org/keywords/visceral-fat","display_name":"visceral fat","score":0.9139999747276306},{"id":"https://openalex.org/keywords/adipose-tissue-endocrine-function","display_name":"adipose tissue endocrine function","score":0.8309999704360962},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9710000157356262},{"id":"https://openalex.org/keywords/hyperinsulinemia","display_name":"hyperinsulinemia","score":0.9940000176429749},{"id":"https://openalex.org/keywords/ovarian-androgen-production","display_name":"ovarian androgen production","score":0.9369999766349792},{"id":"https://openalex.org/keywords/hyperandrogenemia","display_name":"hyperandrogenemia","score":0.9890000224113464},{"id":"https://openalex.org/keywords/aromatization","display_name":"aromatization","score":0.7799999713897705},{"id":"https://openalex.org/keywords/gonadotropin-secretion","display_name":"gonadotropin secretion","score":0.8569999933242798},{"id":"https://openalex.org/keywords/sex-hormone-binding-globulin","display_name":"sex hormone-binding globulin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/growth-hormone","display_name":"growth hormone","score":0.7110000252723694},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-binding-proteins","display_name":"IGF binding proteins","score":0.8619999885559082},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":1.0},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-gonadal-axis","display_name":"hypothalamic-pituitary-gonadal axis","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8639129400253296},{"id":"https://openalex.org/C2780988686","wikidata":"https://www.wikidata.org/wiki/Q14375936","display_name":"Hyperinsulinemia","level":4,"score":0.8538556098937988},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8508276343345642},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.6451709866523743},{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.6217878460884094},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5451712608337402},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5418724417686462},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.5341153740882874},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.5290987491607666},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48736459016799927},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.46207502484321594},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3601263761520386}],"mesh":[{"descriptor_ui":"D000728","descriptor_name":"Androgens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006058","descriptor_name":"Gonadal Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006058","descriptor_name":"Gonadal Disorders","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:16444176","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16444176","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric endocrinology reviews : PER","raw_type":"Journal Article"},{"id":"mag:2415415035","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16444176","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2017282357","https://openalex.org/W4401993288","https://openalex.org/W4416233963","https://openalex.org/W3216822429","https://openalex.org/W2898612726","https://openalex.org/W4407081760","https://openalex.org/W2413560600","https://openalex.org/W2899249719","https://openalex.org/W4404995857","https://openalex.org/W4404957699"],"abstract_inverted_index":{"Excessive":[0],"visceral":[1],"adiposity":[2],"is":[3,12,66],"associated":[4],"with":[5,36],"metabolic":[6],"and":[7,17,59,88,93,107],"reproductive":[8,24,39,112],"abnormalities.":[9],"Adipose":[10],"tissue":[11],"an":[13],"active":[14],"endocrine":[15],"gland":[16],"participates":[18],"in":[19,22,49,69,104,116],"multiple":[20],"mechanisms":[21,106],"the":[23,31,37,50,97],"function":[25,40,113],"of":[26,30,34,53,74,96,102],"women.":[27],"The":[28,100],"nature":[29],"complex":[32],"interaction":[33],"obesity":[35,103],"female":[38,111],"remains":[41],"a":[42],"challenge.":[43],"Several":[44],"links":[45],"have":[46],"been":[47],"implicated":[48],"gonadal":[51],"dysfunction":[52],"obese":[54],"women,":[55],"like":[56],"insulin":[57],"resistance":[58],"hyperinsulinemia,":[60],"via":[61],"which":[62],"ovarian":[63],"androgen":[64],"production":[65],"stimulated":[67],"resulting":[68],"hyperandrogenemia,":[70],"increased":[71,90],"peripheral":[72],"aromatization":[73],"androgens":[75],"to":[76],"estrogens,":[77],"altered":[78,94],"gonadotrophin":[79],"secretion,":[80],"decreased":[81,86],"sex":[82],"hormone":[83],"binding":[84],"globulin,":[85],"GH":[87],"IGFBPs,":[89],"leptin":[91],"levels":[92],"neuroregulation":[95],"hypothalamic-pituitary-gonadal":[98],"axis.":[99],"impact":[101],"these":[105],"their":[108],"influence":[109],"on":[110],"are":[114],"discussed":[115],"this":[117],"article.":[118]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}