{"id":"https://openalex.org/W2415102473","doi":null,"title":"The effects of selected antimicrobials on glucose transport in the rat intestine.","display_name":"The effects of selected antimicrobials on glucose transport in the rat intestine.","publication_year":1979,"publication_date":"1979-02-01","ids":{"openalex":"https://openalex.org/W2415102473","mag":"2415102473","pmid":"https://pubmed.ncbi.nlm.nih.gov/374863"},"language":"en","primary_location":{"id":"pmid:374863","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/374863","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Laboratory animal science","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086113147","display_name":"Hankinson Gj","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G J Hankinson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007021113","display_name":"White Wj","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W J White","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113766922","display_name":"Lang Cm","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C M Lang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.19191429,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"29","issue":"1","first_page":"35","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.3716000020503998,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.3716000020503998,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.1680999994277954,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.08969999849796295,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antimicrobial-agents","display_name":"antimicrobial agents","score":0.656000018119812},{"id":"https://openalex.org/keywords/glucose-transport","display_name":"glucose transport","score":0.7760000228881836},{"id":"https://openalex.org/keywords/intestinal-absorption","display_name":"intestinal absorption","score":0.8899999856948853},{"id":"https://openalex.org/keywords/oxytetracycline","display_name":"oxytetracycline","score":0.9869999885559082},{"id":"https://openalex.org/keywords/ampicillin","display_name":"ampicillin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sucrase","display_name":"sucrase","score":0.8899999856948853},{"id":"https://openalex.org/keywords/maltase","display_name":"maltase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.34599998593330383}],"concepts":[{"id":"https://openalex.org/C2776671240","wikidata":"https://www.wikidata.org/wiki/Q411646","display_name":"Oxytetracycline","level":3,"score":0.9088481664657593},{"id":"https://openalex.org/C2778649499","wikidata":"https://www.wikidata.org/wiki/Q416589","display_name":"Maltase","level":3,"score":0.8165172338485718},{"id":"https://openalex.org/C2776039999","wikidata":"https://www.wikidata.org/wiki/Q2138267","display_name":"Sucrase","level":3,"score":0.7803095579147339},{"id":"https://openalex.org/C2776021129","wikidata":"https://www.wikidata.org/wiki/Q244150","display_name":"Ampicillin","level":3,"score":0.6050739288330078},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.5683919191360474},{"id":"https://openalex.org/C2777882243","wikidata":"https://www.wikidata.org/wiki/Q11090","display_name":"Small intestine","level":2,"score":0.5233254432678223},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46850115060806274},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4576737582683563},{"id":"https://openalex.org/C146201443","wikidata":"https://www.wikidata.org/wiki/Q3544712","display_name":"Disaccharidase","level":3,"score":0.42225056886672974},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.3803340792655945},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.37883514165878296},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35490739345550537},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3429262638092041},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.29177817702293396},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2808164358139038},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.2764972448348999},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2115827202796936}],"mesh":[{"descriptor_ui":"D000520","descriptor_name":"alpha-Glucosidases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000667","descriptor_name":"Ampicillin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007421","descriptor_name":"Intestine, Small","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D007421","descriptor_name":"Intestine, Small","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010118","descriptor_name":"Oxytetracycline","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013393","descriptor_name":"Sucrase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:374863","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/374863","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Laboratory animal science","raw_type":"Journal Article"},{"id":"mag:2415102473","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/374863","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2401679040","https://openalex.org/W2405164602","https://openalex.org/W2397568901","https://openalex.org/W2405027844","https://openalex.org/W2071077450","https://openalex.org/W2038248463","https://openalex.org/W3157238208","https://openalex.org/W3141298613","https://openalex.org/W2405877947","https://openalex.org/W2118185510"],"abstract_inverted_index":{"To":[0],"determine":[1],"whether":[2],"oxytetracycline":[3,72],"hydrochloride":[4],"and":[5,22,44,71,87],"the":[6,16,54,63,69,95,106,111],"sodium":[7],"salt":[8],"of":[9,35,85,94,108],"ampicillin":[10,70],"have":[11],"any":[12,93],"adverse":[13],"effects":[14],"on":[15],"rat":[17],"intestine,":[18],"enteric":[19,83],"enzyme":[20],"levels":[21,84],"glucose":[23,36],"transport":[24,34,55],"rates":[25,56],"were":[26,57,90],"measured":[27],"in":[28,30,82,115,119],"vitro":[29],"rats.":[31],"The":[32,66,97],"intestinal":[33],"did":[37],"not":[38,76],"differ":[39],"significantly":[40,58],"between":[41,68,92],"control":[42,64],"animals":[43,50],"those":[45,61],"pretreated":[46,51],"with":[47,52,105],"ampicillin.":[48],"For":[49],"oxytetracycline,":[53],"lower":[59],"than":[60],"for":[62,113],"group.":[65],"difference":[67],"groups,":[73],"however,":[74],"was":[75],"statistically":[77],"significant.":[78],"No":[79],"significant":[80],"differences":[81],"sucrase":[86],"maltase":[88],"activity":[89],"found":[91],"groups.":[96],"possibility":[98],"that":[99],"some":[100],"antimicrobial":[101],"agents":[102],"may":[103],"interfere":[104],"absorption":[107],"nutrients":[109],"suggested":[110],"need":[112],"caution":[114],"using":[116],"these":[117],"drugs":[118],"experimental":[120],"animals.":[121]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}