{"id":"https://openalex.org/W2414976155","doi":null,"title":"[Free radicals and antioxidant mechanisms. A general outline and its application in clinical practice].","display_name":"[Free radicals and antioxidant mechanisms. A general outline and its application in clinical practice].","publication_year":1997,"publication_date":"1997-06-01","ids":{"openalex":"https://openalex.org/W2414976155","mag":"2414976155","pmid":"https://pubmed.ncbi.nlm.nih.gov/9304136"},"language":"es","primary_location":{"id":"pmid:9304136","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9304136","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista clinica espanola","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103687347","display_name":"A. De La Pena Fernandez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135003","display_name":"Clinica Universidad de Navarra","ror":"https://ror.org/03phm3r45","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210135003"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"A de la Pe\u00f1a Fern\u00e1ndez","raw_affiliation_strings":["Departamento de Medicina Interna, Cl\u00ednica Universitaria de Navarra, Pamplona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Medicina Interna, Cl\u00ednica Universitaria de Navarra, Pamplona","institution_ids":["https://openalex.org/I4210135003"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083436014","display_name":"Pedro Redondo Bell\u00f3n","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Redondo Bell\u00f3n","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.29854491,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"197","issue":"6","first_page":"434","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.9990000128746033},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9459999799728394},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.8360000252723694},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7559999823570251},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.9679999947547913}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.7180643081665039},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4060986042022705},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.23492804169654846}],"mesh":[{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005609","descriptor_name":"Free Radicals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:9304136","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9304136","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista clinica espanola","raw_type":"Journal Article"},{"id":"mag:2414976155","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9304136","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":128,"referenced_works":["https://openalex.org/W1798914","https://openalex.org/W21748295","https://openalex.org/W45520920","https://openalex.org/W99129618","https://openalex.org/W183985724","https://openalex.org/W278448434","https://openalex.org/W347388223","https://openalex.org/W1417497770","https://openalex.org/W1486575542","https://openalex.org/W1492846117","https://openalex.org/W1505511924","https://openalex.org/W1507082667","https://openalex.org/W1511674898","https://openalex.org/W1533084749","https://openalex.org/W1546629881","https://openalex.org/W1555351550","https://openalex.org/W1562095964","https://openalex.org/W1568529372","https://openalex.org/W1579911951","https://openalex.org/W1583870157","https://openalex.org/W1603383904","https://openalex.org/W1652495895","https://openalex.org/W1744753206","https://openalex.org/W1753158170","https://openalex.org/W1801129364","https://openalex.org/W1824045762","https://openalex.org/W1904710053","https://openalex.org/W1938806070","https://openalex.org/W1945689998","https://openalex.org/W1964170890","https://openalex.org/W1964840641","https://openalex.org/W1966989659","https://openalex.org/W1967225346","https://openalex.org/W1967315269","https://openalex.org/W1969164936","https://openalex.org/W1970212660","https://openalex.org/W1970821720","https://openalex.org/W1971313166","https://openalex.org/W1972433360","https://openalex.org/W1975577170","https://openalex.org/W1975980695","https://openalex.org/W1976976477","https://openalex.org/W1979201641","https://openalex.org/W1980307860","https://openalex.org/W1983080992","https://openalex.org/W1983795887","https://openalex.org/W1984661639","https://openalex.org/W1985634870","https://openalex.org/W1986773920","https://openalex.org/W1987093267","https://openalex.org/W1991034099","https://openalex.org/W1991209323","https://openalex.org/W1993151115","https://openalex.org/W1996851774","https://openalex.org/W1997208169","https://openalex.org/W1997723949","https://openalex.org/W1998478734","https://openalex.org/W1999300802","https://openalex.org/W2002769318","https://openalex.org/W2006162058","https://openalex.org/W2007000551","https://openalex.org/W2011817158","https://openalex.org/W2012053348","https://openalex.org/W2012744796","https://openalex.org/W2014608270","https://openalex.org/W2017395526","https://openalex.org/W2023518603","https://openalex.org/W2024052818","https://openalex.org/W2025453958","https://openalex.org/W2026304182","https://openalex.org/W2029302648","https://openalex.org/W2034683799","https://openalex.org/W2037473273","https://openalex.org/W2039092770","https://openalex.org/W2039284286","https://openalex.org/W2039633440","https://openalex.org/W2040692157","https://openalex.org/W2041568449","https://openalex.org/W2045475267","https://openalex.org/W2046254472","https://openalex.org/W2046832043","https://openalex.org/W2047586061","https://openalex.org/W2048988239","https://openalex.org/W2049775789","https://openalex.org/W2053640261","https://openalex.org/W2057257609","https://openalex.org/W2058135945","https://openalex.org/W2058137293","https://openalex.org/W2061052410","https://openalex.org/W2061142443","https://openalex.org/W2061337771","https://openalex.org/W2071095297","https://openalex.org/W2071527810","https://openalex.org/W2071772324","https://openalex.org/W2071929952","https://openalex.org/W2073533590","https://openalex.org/W2079695747","https://openalex.org/W2083843735","https://openalex.org/W2085115437","https://openalex.org/W2085762122","https://openalex.org/W2086536837","https://openalex.org/W2087075582","https://openalex.org/W2096842762","https://openalex.org/W2106170234","https://openalex.org/W2109407065","https://openalex.org/W2113807212","https://openalex.org/W2118822654","https://openalex.org/W2133724802","https://openalex.org/W2135749989","https://openalex.org/W2149855017","https://openalex.org/W2150097377","https://openalex.org/W2154502315","https://openalex.org/W2160339148","https://openalex.org/W2167008900","https://openalex.org/W2174896325","https://openalex.org/W2241449258","https://openalex.org/W2261841113","https://openalex.org/W2323674418","https://openalex.org/W2329711941","https://openalex.org/W2334903440","https://openalex.org/W2339913251","https://openalex.org/W2395615009","https://openalex.org/W2397654580","https://openalex.org/W2422926610","https://openalex.org/W2424194008","https://openalex.org/W2472547351","https://openalex.org/W2495184839","https://openalex.org/W4235303954"],"related_works":["https://openalex.org/W1676949324","https://openalex.org/W7217615696","https://openalex.org/W1565534410","https://openalex.org/W609344067","https://openalex.org/W2782185457","https://openalex.org/W7214698892","https://openalex.org/W7005255877","https://openalex.org/W1975651450","https://openalex.org/W2771052815","https://openalex.org/W2612938744"],"abstract_inverted_index":{"Cada":[0],"vez":[1],"es":[2],"mas":[3],"frecuente":[4],"encontrar":[5],"terminos":[6],"en":[7,35,103],"la":[8,104],"literatura":[9],"medica":[10,106],"y":[11,25,39,50,87,99],"cientifica":[12],"que":[13,57,78,94],"hacen":[14],"referencia":[15],"a":[16,26,71,101],"reacciones":[17,59],"mediadas":[18],"por":[19,48],"radicales":[20],"libres,":[21],"al":[22],"estres":[23,85],"oxidativo":[24,86],"mecanismos":[27,37,83],"de":[28,62,74,81,84],"defensa":[29],"antioxidante.":[30],"Dichos":[31],"fenomenos":[32],"aparecen":[33],"involucrados":[34],"multiples":[36],"fisiopatologicos":[38],"clinicos,":[40],"tales":[41],"como":[42,67],"procesos":[43],"inflamatorios,":[44],"carcinogenesis,":[45],"envejecimiento,":[46],"dano":[47,75],"isquemia-reperfusion":[49],"otros":[51],"1":[52],".":[53],"El":[54],"papel":[55],"lesivo":[56],"estas":[58],"pueden":[60],"producir":[61],"forma":[63],"directa":[64],"o":[65],"bien":[66],"respuesta":[68],"desencadenada":[69],"frente":[70],"otras":[72],"formas":[73],"biologico":[76],"hace":[77],"el":[79,95],"conocimiento":[80],"los":[82],"control":[88],"antioxidante":[89],"sea":[90],"una":[91],"herramienta":[92],"terapeutica":[93],"clinico":[96],"debe":[97],"conocer":[98],"aprender":[100],"manejar":[102],"practica":[105],"diaria.":[107]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
