{"id":"https://openalex.org/W2412824595","doi":null,"title":"Influence of the adrenal medulla on cardiac rhythm disturbances following acute coronary artery occlusions.","display_name":"Influence of the adrenal medulla on cardiac rhythm disturbances following acute coronary artery occlusions.","publication_year":1975,"publication_date":"1975-01-01","ids":{"openalex":"https://openalex.org/W2412824595","mag":"2412824595","pmid":"https://pubmed.ncbi.nlm.nih.gov/1208991"},"language":"en","primary_location":{"id":"pmid:1208991","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1208991","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Recent advances in studies on cardiac structure and metabolism","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017678015","display_name":"Gerald J. Kelliher","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G J Kelliher","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"C Widmer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Widmer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"J Roberts","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Roberts","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9356,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.74701121,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":null,"first_page":"387","last_page":"400"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.6571999788284302,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.6571999788284302,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.24539999663829803,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.055799998342990875,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adrenal-medulla","display_name":"adrenal medulla","score":0.9409999847412109},{"id":"https://openalex.org/keywords/epinephrine","display_name":"epinephrine","score":0.9810000061988831},{"id":"https://openalex.org/keywords/ventricular-fibrillation","display_name":"ventricular fibrillation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/cardiac-arrhythmia","display_name":"cardiac arrhythmias","score":0.9160000085830688},{"id":"https://openalex.org/keywords/left-anterior-descending-coronary-artery-occlusion","display_name":"left anterior descending artery occlusion","score":0.8560000061988831},{"id":"https://openalex.org/keywords/myocardial-ischemia","display_name":"myocardial ischemia","score":0.9139999747276306},{"id":"https://openalex.org/keywords/adrenal-venous-blood","display_name":"adrenal venous blood","score":0.8379999995231628},{"id":"https://openalex.org/keywords/adrenal-vein-ligation","display_name":"adrenal vein ligation","score":0.8230000138282776},{"id":"https://openalex.org/keywords/beta-adrenergic-blockade","display_name":"beta-adrenergic blockade","score":0.9079999923706055},{"id":"https://openalex.org/keywords/sotalol","display_name":"sotalol","score":0.8429999947547913},{"id":"https://openalex.org/keywords/practolol","display_name":"practolol","score":0.8859999775886536},{"id":"https://openalex.org/keywords/cats","display_name":"cats","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C2775859304","wikidata":"https://www.wikidata.org/wiki/Q132621","display_name":"Epinephrine","level":2,"score":0.8327627182006836},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7908800840377808},{"id":"https://openalex.org/C2781005686","wikidata":"https://www.wikidata.org/wiki/Q848662","display_name":"Ventricular fibrillation","level":2,"score":0.6722596287727356},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6565638780593872},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6462975740432739},{"id":"https://openalex.org/C2776268601","wikidata":"https://www.wikidata.org/wiki/Q968808","display_name":"Occlusion","level":2,"score":0.5299927592277527},{"id":"https://openalex.org/C2777597313","wikidata":"https://www.wikidata.org/wiki/Q934888","display_name":"Adrenal medulla","level":3,"score":0.48038655519485474},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4763874411582947},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.4512370228767395},{"id":"https://openalex.org/C2780393670","wikidata":"https://www.wikidata.org/wiki/Q5172192","display_name":"Coronary occlusion","level":3,"score":0.42738550901412964},{"id":"https://openalex.org/C2775894120","wikidata":"https://www.wikidata.org/wiki/Q271663","display_name":"Catecholamine","level":2,"score":0.3795654773712158}],"mesh":[{"descriptor_ui":"D000313","descriptor_name":"Adrenal Medulla","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D000313","descriptor_name":"Adrenal Medulla","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000313","descriptor_name":"Adrenal Medulla","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004837","descriptor_name":"Epinephrine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004837","descriptor_name":"Epinephrine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008012","descriptor_name":"Lidocaine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008026","descriptor_name":"Ligation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011217","descriptor_name":"Practolol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013015","descriptor_name":"Sotalol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014680","descriptor_name":"Veins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014693","descriptor_name":"Ventricular Fibrillation","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1208991","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1208991","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Recent advances in studies on cardiac structure and metabolism","raw_type":"Journal Article"},{"id":"mag:2412824595","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1208991","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2008899056","https://openalex.org/W2341630159","https://openalex.org/W783009413","https://openalex.org/W2132028277","https://openalex.org/W2129327132","https://openalex.org/W2154635613","https://openalex.org/W2110027045","https://openalex.org/W2043840420","https://openalex.org/W2408646069","https://openalex.org/W1993030754"],"abstract_inverted_index":{"The":[0,70,158],"present":[1],"study":[2],"was":[3,61],"designed":[4],"to":[5,108,140,193,196],"examine":[6],"the":[7,13,20,32,40,51,64,80,93,102,111,117,125,148,154,165,176,201],"relationship":[8],"between":[9],"epinephrine":[10,73,94,174,181],"secreted":[11],"from":[12,175],"adrenal":[14,52,71,103,177],"medulla":[15,178],"and":[16,60,68,179],"acute":[17,162],"occlusion":[18,59,78,109,143,163],"of":[19,31,39,66,101,110,119,121,127,130,150,156,164,203],"left":[21],"anterior":[22],"descending":[23],"(LAD)":[24],"coronary":[25,167],"artery":[26,34,113,142,168],"in":[27,37,50,79,86,173,186,200],"alpha-chloralone-anesthetized":[28],"cats.":[29],"Occlusion":[30],"LAD":[33,112,141,166],"produced":[35],"arrhythmia":[36,67,122,151],"all":[38],"animals,":[41],"with":[42,63,132],"39%":[43],"developing":[44],"ventricular":[45,206],"fibrillation":[46],"(VF).":[47],"Epinephrine":[48],"content":[49],"venous":[53,72],"blood":[54],"increased":[55,75,96],"5-fold":[56],"immediately":[57],"after":[58,77],"associated":[62],"development":[65,120],"VF.":[69,128,157],"levels":[74,95],"8-fold":[76],"animals":[81,131],"that":[82,88,161,180],"developed":[83],"VF":[84,188],"while,":[85],"those":[87],"did":[89,114,145],"not":[90,115,146,191],"develop":[91],"VF,":[92],"only":[97],"1.5-fold.":[98],"Bilateral":[99],"ligation":[100],"veins":[104],"1":[105],"hour":[106],"prior":[107,139],"alter":[116],"pattern":[118],"but":[123,152,189],"prevented":[124,153],"occurrence":[126,149],"Pretreatment":[129],"either":[133],"practolol":[134],"or":[135],"sotalol":[136],"15":[137],"min":[138],"also":[144],"affect":[147],"incidence":[155],"data":[159],"indicate":[160],"produces":[169],"a":[170,183],"sharp":[171],"rise":[172],"is":[182],"major":[184],"factor":[185],"producing":[187],"does":[190],"seem":[192],"be":[194],"involved":[195],"any":[197],"great":[198],"extent":[199],"production":[202],"less":[204],"ominous":[205],"arrhythmias.":[207]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}