{"id":"https://openalex.org/W2411208485","doi":null,"title":"[Histomorphometric analysis of the bone tissue in patients with non-insulin-dependent diabetes (DMNID)].","display_name":"[Histomorphometric analysis of the bone tissue in patients with non-insulin-dependent diabetes (DMNID)].","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W2411208485","mag":"2411208485","pmid":"https://pubmed.ncbi.nlm.nih.gov/8762647"},"language":"pt","primary_location":{"id":"pmid:8762647","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8762647","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista do Hospital das Clinicas","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009316602","display_name":"Leite Duarte Me","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161127581","display_name":"Universidade Federal Fluminense","ror":"https://ror.org/02rjhbb08","country_code":"BR","type":"education","lineage":["https://openalex.org/I161127581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"M E Leite Duarte","raw_affiliation_strings":["Departamento de Patologia, Universidade Federal Fluminense"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Patologia, Universidade Federal Fluminense","institution_ids":["https://openalex.org/I161127581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113548150","display_name":"da Silva","orcid":"https://orcid.org/0000-0002-8125-6010","observed_orcids":["https://orcid.org/0000-0002-8125-6010"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R D da Silva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5189,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.73875729,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"51","issue":"1","first_page":"7","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.020500000566244125,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9520000219345093},{"id":"https://openalex.org/keywords/diabetic-osteopenia","display_name":"diabetic osteopenia","score":0.8209999799728394},{"id":"https://openalex.org/keywords/bone-histomorphometry","display_name":"bone histomorphometry","score":0.9309999942779541},{"id":"https://openalex.org/keywords/bone-volume","display_name":"bone volume","score":0.675000011920929},{"id":"https://openalex.org/keywords/osteoid-volume","display_name":"osteoid volume","score":0.921999990940094},{"id":"https://openalex.org/keywords/osteoid-thickness","display_name":"osteoid thickness","score":0.902999997138977},{"id":"https://openalex.org/keywords/cortical-thickness","display_name":"cortical thickness","score":0.8830000162124634},{"id":"https://openalex.org/keywords/osteoblast-surface","display_name":"osteoblast surface","score":0.9879999756813049},{"id":"https://openalex.org/keywords/bone-turnover","display_name":"bone turnover","score":0.9330000281333923},{"id":"https://openalex.org/keywords/iliac-crest-bone","display_name":"iliac crest bone","score":0.8519999980926514},{"id":"https://openalex.org/keywords/mineral-and-bone-metabolism","display_name":"bone mineral metabolism","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C81880429","wikidata":"https://www.wikidata.org/wiki/Q2035067","display_name":"Osteoid","level":2,"score":0.8840047121047974},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7875828146934509},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.780369222164154},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7269148826599121},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6804893016815186},{"id":"https://openalex.org/C2779079599","wikidata":"https://www.wikidata.org/wiki/Q3774464","display_name":"Iliac crest","level":2,"score":0.5476821660995483},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.4958079755306244},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.48660027980804443},{"id":"https://openalex.org/C2781451080","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cortical bone","level":2,"score":0.4804655909538269},{"id":"https://openalex.org/C2777083390","wikidata":"https://www.wikidata.org/wiki/Q1367706","display_name":"Osteopenia","level":4,"score":0.4420660138130188},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.388155460357666},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.30412766337394714},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.20008239150047302},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.16556373238563538}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001851","descriptor_name":"Bone Diseases, Metabolic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001851","descriptor_name":"Bone Diseases, Metabolic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8762647","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8762647","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista do Hospital das Clinicas","raw_type":"English Abstract"},{"id":"mag:2411208485","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8762647","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1986306131","https://openalex.org/W4240345606","https://openalex.org/W1996558448","https://openalex.org/W1963619357","https://openalex.org/W2147802933","https://openalex.org/W2029243279","https://openalex.org/W2402785144","https://openalex.org/W2084332919","https://openalex.org/W2029204013","https://openalex.org/W2002036528"],"abstract_inverted_index":{"The":[0,78],"effects":[1],"of":[2,33,111,170,201,206],"long-term":[3],"diabetes":[4,23,35,65],"mellitus":[5,24,36,66],"on":[6,38],"mineral":[7],"metabolism":[8],"and":[9,60,68,104,157,176,203],"bone":[10,28,39,52,94,137,194],"integrity":[11],"remain":[12],"ill":[13],"defined.":[14],"Several":[15],"studies":[16],"have":[17,26],"shown":[18],"that":[19,120,185],"patients":[20,57],"with":[21,63,107,173],"insulin-dependent":[22],"(IDDM)":[25],"reduced":[27],"mass.":[29],"However,":[30],"the":[31,90,93,133,186,216],"effect":[32],"non-insulin-dependent":[34,64],"(NIDDM)":[37,67],"mass":[40],"has":[41],"been":[42],"controversial.":[43],"Quantitative":[44],"histologic":[45],"assessments":[46],"were":[47,96,130],"completed":[48],"in":[49,132,179,198,215],"iliac":[50],"crest":[51],"samples":[53,95],"obtained":[54],"from":[55,98],"26":[56],"(13":[58],"male":[59,103],"13":[61],"female)":[62,106],"normal":[69],"renal":[70],"function":[71],"(serum":[72],"creatinine":[73],"1.00":[74],"+/-":[75,83,113],"0.04":[76],"mg/dl).":[77],"mean":[79,109],"age":[80,110],"was":[81,212],"67.42":[82],"2.74":[84],"yrs,":[85,115,118],"range":[86,116],"50-89":[87],"yrs.":[88],"For":[89],"control":[91],"group":[92,135],"taken":[97],"20":[99],"non-diabetic":[100],"subjects":[101],"(11":[102],"9":[105],"a":[108,199,213],"57.95":[112],"3.96":[114],"33-91":[117],"n.s,":[119],"had":[121],"suffered":[122],"sudden":[123],"or":[124],"violent":[125],"death.":[126],"Significant":[127],"lower":[128],"values":[129],"present":[131],"diabetic":[134,189],"for":[136],"volume":[138,143,172],"(p":[139,144,149,154,160],"<":[140,145,150,155,161],"0.0001),":[141,151],"osteoid":[142,147,171,174,177],"0.005),":[146],"thickness":[148,153,175],"cortical":[152,217],"0.05)":[156],"osteoblast":[158],"surface":[159,178],"0.05).":[162],"Linear":[163],"regression":[164],"analysis":[165],"revealed":[166],"significant":[167],"positive":[168],"correlations":[169],"both":[180],"groups.":[181],"Our":[182],"results":[183],"suggest":[184],"mechanism(s)":[187],"underlying":[188],"osteopenia":[190],"may":[191],"involve":[192],"decreased":[193],"turnover":[195],"as":[196],"reflected":[197],"paucity":[200],"osteoblasts":[202],"diminished":[204],"quantities":[205],"osteoid.":[207],"A":[208],"proeminent":[209],"additional":[210],"feature":[211],"reduction":[214],"thickness.":[218]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}