{"id":"https://openalex.org/W2410313145","doi":null,"title":"Comparative effects of calcitriol and parathyroid hormone on serum aluminum in vitamin D-depleted rabbits fed an aluminum-supplemented diet.","display_name":"Comparative effects of calcitriol and parathyroid hormone on serum aluminum in vitamin D-depleted rabbits fed an aluminum-supplemented diet.","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W2410313145","mag":"2410313145","pmid":"https://pubmed.ncbi.nlm.nih.gov/8165367"},"language":"en","primary_location":{"id":"pmid:8165367","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8165367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research communications in chemical pathology and pharmacology","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"J F Long","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J F Long","raw_affiliation_strings":["Department of Veterinary Pathobiology, Ohio State University, Columbus 43210"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathobiology, Ohio State University, Columbus 43210","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007141260","display_name":"Larry Allen Nagode","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L A Nagode","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111633605","display_name":"C.L. Steinmeyer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C L Steinmeyer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5010061915","display_name":"G Renkes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Renkes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0156,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.75896161,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"83","issue":"1","first_page":"3","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12211","display_name":"Aluminum toxicity and tolerance in plants and animals","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12211","display_name":"Aluminum toxicity and tolerance in plants and animals","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.2069000005722046,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/1-25-dihydroxyvitamin-d3","display_name":"1,25-dihydroxyvitamin D3","score":0.8450000286102295},{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.9959999918937683},{"id":"https://openalex.org/keywords/serum-aluminum","display_name":"serum aluminum","score":0.8579999804496765},{"id":"https://openalex.org/keywords/aluminum-absorption","display_name":"aluminum absorption","score":0.781000018119812},{"id":"https://openalex.org/keywords/aluminum-lactate","display_name":"aluminum lactate","score":0.5889999866485596},{"id":"https://openalex.org/keywords/secondary-hyperparathyroidism","display_name":"secondary hyperparathyroidism","score":0.9959999918937683},{"id":"https://openalex.org/keywords/aluminum-toxicity","display_name":"aluminum toxicity","score":0.5379999876022339},{"id":"https://openalex.org/keywords/osmotic-pump-infusion","display_name":"osmotic pump infusion","score":0.7689999938011169},{"id":"https://openalex.org/keywords/rabbits","display_name":"rabbits","score":0.31200000643730164}],"concepts":[{"id":"https://openalex.org/C2776079296","wikidata":"https://www.wikidata.org/wiki/Q139195","display_name":"Calcitriol","level":3,"score":0.9764852523803711},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.8205775618553162},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7732694149017334},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7241341471672058},{"id":"https://openalex.org/C2775945674","wikidata":"https://www.wikidata.org/wiki/Q1344835","display_name":"Hyperparathyroidism","level":2,"score":0.5866692066192627},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.5525804758071899},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.5051527619361877},{"id":"https://openalex.org/C2778838027","wikidata":"https://www.wikidata.org/wiki/Q3622611","display_name":"Secondary hyperparathyroidism","level":4,"score":0.4954947233200073},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4806062877178192},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.43394118547439575},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.3876885175704956},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3257785439491272}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000535","descriptor_name":"Aluminum","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000535","descriptor_name":"Aluminum","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000535","descriptor_name":"Aluminum","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002117","descriptor_name":"Calcitriol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002117","descriptor_name":"Calcitriol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006961","descriptor_name":"Hyperparathyroidism","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007260","descriptor_name":"Infusion Pumps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007408","descriptor_name":"Intestinal Absorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014808","descriptor_name":"Vitamin D Deficiency","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014808","descriptor_name":"Vitamin D Deficiency","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:8165367","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8165367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research communications in chemical pathology and pharmacology","raw_type":"Comparative Study"},{"id":"mag:2410313145","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8165367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"},{"display_name":"Zero hunger","score":0.40450000762939453,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7932719266","display_name":"DIETARY INDUCED ALUMINUM ENCEPHALOPATHY","funder_award_id":"R01AG005700","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2463347230","https://openalex.org/W2074577288","https://openalex.org/W2095298795","https://openalex.org/W2019210530","https://openalex.org/W1994785914","https://openalex.org/W2408863817","https://openalex.org/W2012306041","https://openalex.org/W2401610906","https://openalex.org/W2034423611","https://openalex.org/W2461726541"],"abstract_inverted_index":{"Under":[0],"normal":[1],"circumstances,":[2],"the":[3,8,46,69,87,102,117,138,171,193,206,212,221,226,241,275,302,306,309,322,372,376],"body":[4],"barriers":[5],"effectively":[6],"limit":[7],"entry":[9],"and":[10,20,75,106,144,187,264,338],"retention":[11],"of":[12,26,35,48,52,72,104,120,127,141,149,155,173,225,252,261,279,308,316,324,351,359,383],"dietary":[13],"aluminum.":[14],"However,":[15],"both":[16,73,184],"parathyroid":[17],"hormone":[18],"(PTH)":[19],"calcitriol":[21,49,76,105,113,160,189,209,253],"(physiologically":[22],"active":[23],"hormonal":[24],"form":[25],"vitamin":[27,97,352],"D3)":[28],"have":[29,288],"been":[30,349],"reported":[31],"to":[32,56,60,109,134,249,301],"produce":[33],"elevation":[34],"serum":[36,70,142,150,185,188,199,208,230,246,262,265,296,319,377],"aluminum":[37,62,175,200,231,263,297,320,342,378],"in":[38,124,211,240,295,321,356],"animals":[39],"fed":[40,95,285],"an":[41,64,174,341],"aluminum-supplemented":[42,286],"ration.":[43],"To":[44,85,152,311],"compare":[45],"effects":[47],"with":[50,54,116,157,170,205,330],"those":[51],"PTH":[53,74,143,156,186,247,255,266,317,334,369],"reference":[55],"their":[57,366],"putative":[58],"effect":[59,315],"enhance":[61],"absorption,":[63],"experiment":[65],"was":[66,132,164,202],"designed":[67],"wherein":[68],"levels":[71,232],"would":[77],"be":[78,135],"changing":[79],"markedly":[80],"during":[81,192,220,274],"a":[82,96,125,145,258,291,357,381],"short":[83],"time-frame.":[84],"condition":[86],"rabbits":[88,213,282,327],"used":[89],"for":[90,183,313],"this":[91],"comparison,":[92],"they":[93],"were":[94,181,328,354],"D-free":[98],"diet,":[99],"which":[100,299],"caused":[101],"level":[103,140,148,201,210,298,304],"its":[107],"precursors":[108],"decline":[110],"rapidly.":[111],"The":[112,228],"deficit":[114],"together":[115],"ensuing":[118],"lack":[119],"calcium":[121],"absorption":[122],"resulted":[123],"state":[126,358],"secondary":[128,361],"hyperparathyroidism.":[129],"Vitamin":[130],"D-depletion":[131],"shown":[133,289,364],"complete":[136],"by":[137,166,305,365],"high":[139],"low":[146],"(unmeasurable)":[147],"calcitriol.":[151],"enable":[153],"comparison":[154],"calcitriol,":[158,325],"exogenous":[159],"infusion":[161],"(60":[162],"IU/day)":[163],"started":[165,339],"osmotic":[167,331],"pump":[168],"simultaneously":[169],"beginning":[172],"(aluminum":[176],"lactate)":[177],"supplemented":[178,343],"diet.":[179,344],"Aliquots":[180],"collected":[182],"at":[190],"intervals":[191],"7":[194,242,373],"day":[195,243,374],"study.":[196],"A":[197],"rising":[198,207],"highly":[203],"correlated":[204],"(r":[214,267],"=":[215,218,268,271],"0.903,":[216],"p":[217,270],"0.036)":[219],"first":[222,276],"4":[223,277],"days":[224,278],"infusion.":[227,280],"mean":[229,382],"rose":[233,379],"nearly":[234],"13":[235],"parts":[236],"per":[237,387],"billion":[238,388],"(ppb)":[239],"period.":[244],"Declining":[245],"(due":[248],"feedback":[250],"mechanisms":[251],"suppressing":[254],"synthesis)":[256],"showed":[257],"negative":[259],"correlation":[260],"-0.959,":[269],"<":[272],"0.01)":[273],"Control":[281],"(vitamin-D":[283],"depleted)":[284],"rations":[287],"only":[290,380],"minimal":[292],"transient":[293],"rise":[294],"returned":[300],"pre-test":[303],"end":[307],"week.":[310],"test":[312],"any":[314],"on":[318,340],"absence":[323],"five":[326],"implanted":[329],"pumps":[332],"infusing":[333],"(mean":[335],"6.0":[336],"U/hr)":[337],"These":[345],"rabbits,":[346],"having":[347],"previously":[348],"depleted":[350],"D":[353],"already":[355],"nutritional":[360],"hyperparathyroidism":[362],"as":[363],"elevated":[367],"pretest":[368],"levels.":[370],"During":[371],"infusion,":[375],"approximately":[384],"1":[385],"part":[386],"(ppb).(ABSTRACT":[389],"TRUNCATED":[390],"AT":[391],"400":[392],"WORDS)":[393]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}