{"id":"https://openalex.org/W2410241986","doi":null,"title":"[Significance of CEA in gastric and colorectal cancer].","display_name":"[Significance of CEA in gastric and colorectal cancer].","publication_year":1985,"publication_date":"1985-04-01","ids":{"openalex":"https://openalex.org/W2410241986","mag":"2410241986","pmid":"https://pubmed.ncbi.nlm.nih.gov/3889583"},"language":"ja","primary_location":{"id":"pmid:3889583","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3889583","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Geka Gakkai zasshi","raw_type":"English Abstract"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082747438","display_name":"Koichiro Uehara","orcid":"https://orcid.org/0009-0006-2302-711X","observed_orcids":["https://orcid.org/0009-0006-2302-711X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Uehara","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101573751","display_name":"Yosuke Miyamoto","orcid":"https://orcid.org/0000-0002-1647-6535","observed_orcids":["https://orcid.org/0000-0002-1647-6535"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Miyamoto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078253665","display_name":"Masaru Izuo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Izuo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026637925","display_name":"Hiroshi Shiozaki","orcid":"https://orcid.org/0000-0002-7175-0824","observed_orcids":["https://orcid.org/0000-0002-7175-0824"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Shiozaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109285939","display_name":"S Aiba","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Aiba","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5022569261","display_name":"Hiroko Matsumoto","orcid":"https://orcid.org/0000-0002-2270-7651","observed_orcids":["https://orcid.org/0000-0002-2270-7651"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Matsumoto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2142,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.81373335,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"86","issue":"4","first_page":"435","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.5396000146865845,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.5396000146865845,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12379","display_name":"Cancer Diagnosis and Treatment","score":0.27390000224113464,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.06669999659061432,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carcinoembryonic-antigen","display_name":"carcinoembryonic antigen","score":0.9980000257492065},{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.8939999938011169},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/serum-cea","display_name":"serum CEA","score":0.8019999861717224},{"id":"https://openalex.org/keywords/immunohistochemical-staining","display_name":"immunohistochemical staining","score":0.781000018119812},{"id":"https://openalex.org/keywords/postoperative-monitoring","display_name":"postoperative monitoring","score":0.597000002861023},{"id":"https://openalex.org/keywords/tumor-resectability","display_name":"tumor resectability","score":0.7670000195503235},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/tumor-differentiation","display_name":"tumor differentiation","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.875198483467102},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.7207373380661011},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.7174578905105591},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.6502261161804199},{"id":"https://openalex.org/C2777387746","wikidata":"https://www.wikidata.org/wiki/Q769706","display_name":"Carcinoembryonic antigen","level":3,"score":0.5540475249290466},{"id":"https://openalex.org/C2993216161","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colonic cancer","level":4,"score":0.5264894366264343},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.47331106662750244},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.46793171763420105},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.455240935087204},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.4411855638027191},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.41824644804000854},{"id":"https://openalex.org/C2992571226","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node metastasis","level":4,"score":0.4123965799808502},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.40414777398109436},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.327613890171051}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002272","descriptor_name":"Carcinoembryonic Antigen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3889583","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3889583","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Geka Gakkai zasshi","raw_type":"English Abstract"},{"id":"mag:2410241986","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3889583","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W147047715","https://openalex.org/W1998751826","https://openalex.org/W2013550204","https://openalex.org/W2133653181","https://openalex.org/W2352925272","https://openalex.org/W2083253173","https://openalex.org/W2411956124","https://openalex.org/W2061264791","https://openalex.org/W2274140883","https://openalex.org/W2413971592"],"abstract_inverted_index":{"The":[0,91],"determination":[1],"of":[2,12,28,59,84,89,95,118,123,129,132,168,176],"serum":[3,36,51,75,119,158],"CEA":[4,8,37,49,52,72,76,92,98,115,130,172],"(Sandwich":[5],"method)":[6,11],"and":[7,24,31,61,74,86,109,144,186],"staining":[9,99,131,170,178],"(PAP":[10],"excised":[13],"specimens":[14],"were":[15,38,110,192],"performed":[16],"in":[17,81,102,106,120,141,147,183,189,194],"patients":[18],"with":[19,40,97,171],"gastric":[20,103,142,184],"or":[21,180],"colorectal":[22],"cancer,":[23,60,104,108,143],"the":[25,32,41,57,65,82,87,114,121,127,151,166,174],"biological":[26],"characteristics":[27],"each":[29],"cancer":[30,46,69,85,185,191],"factors":[33],"to":[34,113],"increase":[35],"studied":[39],"following":[42],"results:":[43],"As":[44],"colonic":[45,107,148,190],"has":[47,70],"strong":[48],"productivity,":[50,73],"can":[53],"be":[54],"useful":[55,80],"for":[56,64],"detection":[58,83],"especially":[62],"effective":[63],"postoperative":[66],"observation.":[67],"Gastric":[68],"weak":[71],"is":[77],"not":[78],"so":[79],"judgement":[88],"resectability.":[90],"positive":[93,116],"rate":[94,117],"tissue":[96,169],"was":[100,137],"80%":[101],"100%":[105],"nearly":[111],"equal":[112],"group":[122],"terminal":[124],"stage.":[125],"In":[126],"mode":[128,175],"cancerous":[133],"cells,":[134],"IV":[135],"type":[136,146,182,188],"observed":[138,193],"most":[139],"frequently":[140],"I":[145,181,187],"cancer.":[149],"Among":[150],"resected":[152],"cases":[153],"showing":[154],"more":[155],"than":[156],"7ng/ml":[157],"CEA,":[159],"differentiated":[160],"type,":[161],"lymph":[162],"node":[163],"metastasis":[164],"(+),":[165],"degree":[167],"staining,":[173],"cell":[177],"O":[179],"common.":[195]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}