{"id":"https://openalex.org/W2410091045","doi":"https://doi.org/10.1097/00007611-197706000-00016","title":"Frequency of HLA Antigens in Chronic Myelocytic Leukemia","display_name":"Frequency of HLA Antigens in Chronic Myelocytic Leukemia","publication_year":1977,"publication_date":"1977-06-01","ids":{"openalex":"https://openalex.org/W2410091045","doi":"https://doi.org/10.1097/00007611-197706000-00016","mag":"2410091045","pmid":"https://pubmed.ncbi.nlm.nih.gov/69321"},"language":"en","primary_location":{"id":"doi:10.1097/00007611-197706000-00016","doi":"https://doi.org/10.1097/00007611-197706000-00016","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007611-197706000-00016","pdf_url":null,"source":{"id":"https://openalex.org/S89143414","display_name":"Southern Medical Journal","issn_l":"0038-4348","issn":["0038-4348","1541-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111817244","display_name":"Jeane P. Hester","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JEANE P. HESTER","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046816748","display_name":"Roger D. Rossen","orcid":"https://orcid.org/0000-0002-0897-0867","observed_orcids":["https://orcid.org/0000-0002-0897-0867"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ROGER ROSSEN","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100688040","display_name":"Jos\u00e9 Manuel Trujillo","orcid":"https://orcid.org/0000-0003-1772-0285","observed_orcids":["https://orcid.org/0000-0003-1772-0285"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JOSE TRUJILLO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111673665","display_name":"Kenneth B. McCredie","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"KENNETH B. McCREDIE","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111473566","display_name":"Emil J. Freireich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"EMIL J. FREIREICH","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.28733736,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"70","issue":"6","first_page":"691","last_page":"693"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11215","display_name":"Chronic Myeloid Leukemia Treatments","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11215","display_name":"Chronic Myeloid Leukemia Treatments","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-myeloid-leukemia","display_name":"chronic myeloid leukemia","score":0.8859999775886536},{"id":"https://openalex.org/keywords/hla-antigens","display_name":"HLA antigens","score":0.9750000238418579},{"id":"https://openalex.org/keywords/hla-b7","display_name":"HLA-B7","score":0.7620000243186951},{"id":"https://openalex.org/keywords/hla-b12","display_name":"HLA-B12","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hla-a3","display_name":"HLA-A3","score":0.8700000047683716},{"id":"https://openalex.org/keywords/hla-b5","display_name":"HLA-B5","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hla-b8","display_name":"HLA-B8","score":0.9760000109672546},{"id":"https://openalex.org/keywords/hla-typing","display_name":"HLA typing","score":0.5220000147819519},{"id":"https://openalex.org/keywords/microcytotoxicity-test","display_name":"microcytotoxicity test","score":0.703000009059906},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.35600000619888306},{"id":"https://openalex.org/keywords/platelet-donors","display_name":"platelet donors","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8030986785888672},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.7859563231468201},{"id":"https://openalex.org/C202965653","wikidata":"https://www.wikidata.org/wiki/Q2664028","display_name":"Histocompatibility","level":4,"score":0.7278785705566406},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.7210491299629211},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.632285475730896},{"id":"https://openalex.org/C2776960273","wikidata":"https://www.wikidata.org/wiki/Q729735","display_name":"Chronic myelogenous leukemia","level":3,"score":0.6176876425743103},{"id":"https://openalex.org/C2909478873","wikidata":"https://www.wikidata.org/wiki/Q3991680","display_name":"Histocompatibility Testing","level":4,"score":0.5370883345603943},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.5189875960350037},{"id":"https://openalex.org/C2781209916","wikidata":"https://www.wikidata.org/wiki/Q3215756","display_name":"Typing","level":2,"score":0.4636934995651245},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11050683259963989},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06179729104042053}],"mesh":[{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002869","descriptor_name":"Chromosome Aberrations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002904","descriptor_name":"Chromosomes, Human, 21-22 and Y","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006649","descriptor_name":"Histocompatibility Antigens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007951","descriptor_name":"Leukemia, Myeloid","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007951","descriptor_name":"Leukemia, Myeloid","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007951","descriptor_name":"Leukemia, Myeloid","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013781","descriptor_name":"Texas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00007611-197706000-00016","doi":"https://doi.org/10.1097/00007611-197706000-00016","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007611-197706000-00016","pdf_url":null,"source":{"id":"https://openalex.org/S89143414","display_name":"Southern Medical Journal","issn_l":"0038-4348","issn":["0038-4348","1541-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern Medical Journal","raw_type":"journal-article"},{"id":"pmid:69321","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/69321","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern medical journal","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7699999809265137}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2752826208","https://openalex.org/W2143098637","https://openalex.org/W2170548861","https://openalex.org/W1974036792","https://openalex.org/W2363359376","https://openalex.org/W96043173","https://openalex.org/W2011829178","https://openalex.org/W1965448482","https://openalex.org/W1976408680","https://openalex.org/W2995452520"],"abstract_inverted_index":{"Histocompatibility":[0],"antigen":[1],"(HLA)":[2],"phenotypes":[3],"of":[4,38,80,122,148,156],"34":[5],"patients":[6,68,83,94,104,131],"with":[7,17,132],"Ph1+":[8],"chronic":[9],"myelogenous":[10],"leukemia":[11],"(CML)":[12],"were":[13,23,64,127],"evaluated":[14],"for":[15,49],"association":[16],"HLA":[18,41],"antigens.":[19],"Two":[20],"control":[21,138],"populations":[22],"compared":[24,69,86,134],"to":[25,70,87,135],"the":[26],"CML":[27,67,133],"patients:":[28],"142":[29],"normal":[30,36,137],"volunteer":[31],"platelet":[32,72],"donors,":[33],"and":[34,55,62,73,90,99,101,110,120,125,150],"160":[35],"donors":[37],"granulocyte":[39,74],"transfusions.":[40],"typing":[42],"was":[43,77,117,144,152],"done":[44],"by":[45],"lymphocyte":[46],"microcytotoxicity":[47],"tests":[48],"nine":[50],"antigens":[51,57],"on":[52,58],"sublocus":[53,59],"A":[54],"15":[56],"B.":[60],"HLA-B7":[61,149],"HLA-B12":[63],"decreased":[65],"in":[66,82,130,142],"both":[71],"donors.":[75],"There":[76],"increased":[78,129],"frequency":[79,147],"HLA-A3":[81],"(41%)":[84],"as":[85],"controls":[88,97,107],"(25%":[89],"33%);":[91],"HLA-B5":[92,124],"-":[93,103],"=":[95,105,108,113],"20%;":[96],"8%":[98],"6%;":[100],"HLA-BW17":[102,126],"17%;":[106],"6%":[109],"3%":[111],"(P":[112],"0.01).":[114],"Median":[115],"survival":[116],"24+":[118],"months":[119],"independent":[121],"HLA.":[123],"significantly":[128],"two":[136],"populations.":[139],"No":[140],"increase":[141],"HLA-B8":[143],"seen.":[145],"Decreased":[146],"B12":[151],"noted.":[153],"The":[154],"significance":[155],"these":[157],"differences":[158],"is":[159],"being":[160],"evaluated.":[161]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}