{"id":"https://openalex.org/W2409705343","doi":"https://doi.org/10.1055/s-2008-1035738","title":"Immunhistochemischer und serologischer Nachweis des CA-125 bei Patientinnen mit Peritonealtuberkulose und Aszites","display_name":"Immunhistochemischer und serologischer Nachweis des CA-125 bei Patientinnen mit Peritonealtuberkulose und Aszites","publication_year":1989,"publication_date":"1989-01-01","ids":{"openalex":"https://openalex.org/W2409705343","doi":"https://doi.org/10.1055/s-2008-1035738","mag":"2409705343","pmid":"https://pubmed.ncbi.nlm.nih.gov/2917708"},"language":"de","primary_location":{"id":"doi:10.1055/s-2008-1035738","doi":"https://doi.org/10.1055/s-2008-1035738","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2008-1035738","pdf_url":null,"source":{"id":"https://openalex.org/S146294059","display_name":"Geburtshilfe und Frauenheilkunde","issn_l":"0016-5751","issn":["0016-5751","1438-8804","2199-6989"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Geburtshilfe und Frauenheilkunde","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090596715","display_name":"G R\u00f3nay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G. Ronay","raw_affiliation_strings":["Frauenklinik mit Poliklinik der Universit\u00e4t Erlangen-N\u00fcrnberg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Frauenklinik mit Poliklinik der Universit\u00e4t Erlangen-N\u00fcrnberg","institution_ids":["https://openalex.org/I181369854","https://openalex.org/I4210088053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112162596","display_name":"W. J\u00e4ger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. J\u00e4ger","raw_affiliation_strings":["Frauenklinik mit Poliklinik der Universit\u00e4t Erlangen-N\u00fcrnberg (Dir.: Prof. Dr. med. N. Lang)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Frauenklinik mit Poliklinik der Universit\u00e4t Erlangen-N\u00fcrnberg (Dir.: Prof. Dr. med. N. Lang)","institution_ids":["https://openalex.org/I4210088053"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108431656","display_name":"A. H. Tulusan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A. Tulusan","raw_affiliation_strings":["Frauenklinik mit Poliklinik der Universit\u00e4t Erlangen-N\u00fcrnberg (Dir.: Prof. Dr. med. N. Lang)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Frauenklinik mit Poliklinik der Universit\u00e4t Erlangen-N\u00fcrnberg (Dir.: Prof. Dr. med. N. Lang)","institution_ids":["https://openalex.org/I4210088053"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3578,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.60524747,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"49","issue":"01","first_page":"61","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12578","display_name":"Diagnosis and treatment of tuberculosis","score":0.9208999872207642,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12578","display_name":"Diagnosis and treatment of tuberculosis","score":0.9208999872207642,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.06199999898672104,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ca125","display_name":"CA125","score":0.9980000257492065},{"id":"https://openalex.org/keywords/tuberculous-peritonitis","display_name":"tuberculous peritonitis","score":0.9509999752044678},{"id":"https://openalex.org/keywords/tuberculous-ascites","display_name":"tuberculous ascites","score":0.8140000104904175},{"id":"https://openalex.org/keywords/miliary-tuberculosis","display_name":"miliary tuberculosis","score":0.8949999809265137},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.6510000228881836},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.47699999809265137},{"id":"https://openalex.org/keywords/granulomatous-inflammation","display_name":"granulomatous inflammation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.8149999976158142},{"id":"https://openalex.org/keywords/ruptured-ovarian-cyst","display_name":"ovarian cyst rupture","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C2780496750","wikidata":"https://www.wikidata.org/wiki/Q193889","display_name":"Ascites","level":2,"score":0.6561487317085266},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.5782390832901001},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5720911026000977},{"id":"https://openalex.org/C3019054536","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian carcinoma","level":4,"score":0.5539454817771912},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5219911336898804},{"id":"https://openalex.org/C2780778865","wikidata":"https://www.wikidata.org/wiki/Q1130374","display_name":"Laparotomy","level":2,"score":0.5154791474342346},{"id":"https://openalex.org/C2778329809","wikidata":"https://www.wikidata.org/wiki/Q17583","display_name":"Miliary tuberculosis","level":3,"score":0.5143340826034546},{"id":"https://openalex.org/C2780140890","wikidata":"https://www.wikidata.org/wiki/Q1129338","display_name":"Granuloma","level":2,"score":0.4221540093421936},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.23837321996688843},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.17757046222686768},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1749216914176941},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.13571211695671082},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.0934583842754364}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001201","descriptor_name":"Ascites","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010537","descriptor_name":"Peritoneum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014395","descriptor_name":"Peritonitis, Tuberculous","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D014395","descriptor_name":"Peritonitis, Tuberculous","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015295","descriptor_name":"Antigens, Tumor-Associated, Carbohydrate","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1055/s-2008-1035738","doi":"https://doi.org/10.1055/s-2008-1035738","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2008-1035738","pdf_url":null,"source":{"id":"https://openalex.org/S146294059","display_name":"Geburtshilfe und Frauenheilkunde","issn_l":"0016-5751","issn":["0016-5751","1438-8804","2199-6989"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Geburtshilfe und Frauenheilkunde","raw_type":"journal-article"},{"id":"pmid:2917708","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2917708","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Geburtshilfe und Frauenheilkunde","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2104669534","https://openalex.org/W2438739278","https://openalex.org/W2310478800","https://openalex.org/W2472066220","https://openalex.org/W2216277017","https://openalex.org/W83876167","https://openalex.org/W2095516325","https://openalex.org/W4311522019","https://openalex.org/W2144255653","https://openalex.org/W1569327141"],"abstract_inverted_index":{"We":[0],"report":[1],"on":[2],"two":[3],"young":[4],"patients":[5],"with":[6,55],"massively":[7],"elevated":[8],"CA-125":[9,58,91,96],"serum":[10],"level":[11],"of":[12,26,84,87,104],"290":[13],"and":[14,50,90],"264":[15],"U/ml":[16],"respectively,":[17],"who":[18],"clinically":[19],"exhibited":[20],"suddenly":[21],"occurring":[22],"ascites.":[23],"The":[24],"diagnosis":[25],"ovarian":[27,31],"carcinoma":[28],"or":[29],"ruptured":[30],"cystoma":[32],"led":[33],"to":[34],"a":[35,40,108],"laparotomy.":[36],"During":[37],"the":[38,65,75,102,105,111],"operation,":[39],"disseminating":[41],"granulomatous":[42],"inflammation":[43],"was":[44,47,59],"evident,":[45],"which":[46],"identified":[48],"histologically":[49],"microbiologically":[51],"as":[52],"miliary":[53],"tuberculosis":[54,89,106],"peritoneal":[56],"invasion.":[57],"immunohistochemically":[60],"localised,":[61],"sharply":[62],"demarcated":[63],"around":[64],"tuberculous":[66],"granuloma.":[67],"A":[68,79],"possible":[69],"explanation":[70],"for":[71],"this":[72],"finding":[73],"is":[74],"inflammatory":[76],"mesothelial":[77],"proliferation.":[78],"similarity":[80],"in":[81],"antigenic":[82],"structures":[83],"membrane":[85],"components":[86],"M.":[88],"cannot":[92],"be":[93],"excluded.":[94],"Serum":[95],"levels":[97],"tested":[98],"6":[99],"months":[100],"after":[101],"treatment":[103],"showed":[107],"value":[109],"within":[110],"normal":[112],"range":[113],"(less":[114],"than":[115],"35":[116],"U/ml).":[117]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}