{"id":"https://openalex.org/W2409655596","doi":null,"title":"The use of G-CSF in normal neutrophil donors.","display_name":"The use of G-CSF in normal neutrophil donors.","publication_year":2000,"publication_date":"2000-03-01","ids":{"openalex":"https://openalex.org/W2409655596","mag":"2409655596","pmid":"https://pubmed.ncbi.nlm.nih.gov/10855364"},"language":"en","primary_location":{"id":"pmid:10855364","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10855364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales de medecine interne","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113697653","display_name":"Thomas H. Price","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799735646","display_name":"Bloodworks Northwest","ror":"https://ror.org/00ek9j693","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2799735646"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"T H Price","raw_affiliation_strings":["Puget Sound Blood Center and Program, Seattle, WA 98104-1256, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Puget Sound Blood Center and Program, Seattle, WA 98104-1256, USA","institution_ids":["https://openalex.org/I2799735646"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113697653"],"corresponding_institution_ids":["https://openalex.org/I2799735646"],"apc_list":null,"apc_paid":null,"fwci":0.6932,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.7229058,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"151","issue":"2","first_page":"115","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections","score":0.7886000275611877,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections","score":0.7886000275611877,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12919","display_name":"Blood disorders and treatments","score":0.16019999980926514,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.03539999946951866,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/granulocyte-colony-stimulating-factor","display_name":"granulocyte colony-stimulating factor","score":0.9589999914169312},{"id":"https://openalex.org/keywords/neutrophil-transfusion","display_name":"neutrophil transfusion","score":0.7940000295639038},{"id":"https://openalex.org/keywords/leukapheresis","display_name":"leukapheresis","score":0.9120000004768372},{"id":"https://openalex.org/keywords/corticosteroids","display_name":"corticosteroids","score":0.8669999837875366},{"id":"https://openalex.org/keywords/neutrophil-migration","display_name":"neutrophil migration","score":0.7870000004768372},{"id":"https://openalex.org/keywords/neutropenic-patients","display_name":"neutropenic patients","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9713132381439209},{"id":"https://openalex.org/C2777802486","wikidata":"https://www.wikidata.org/wiki/Q491741","display_name":"Neutrophilia","level":2,"score":0.9381300210952759},{"id":"https://openalex.org/C2777371436","wikidata":"https://www.wikidata.org/wiki/Q3237071","display_name":"Leukapheresis","level":4,"score":0.8038276433944702},{"id":"https://openalex.org/C2777063308","wikidata":"https://www.wikidata.org/wiki/Q1435822","display_name":"Neutropenia","level":3,"score":0.7843585014343262},{"id":"https://openalex.org/C74133956","wikidata":"https://www.wikidata.org/wiki/Q4669824","display_name":"Absolute neutrophil count","level":4,"score":0.6018056273460388},{"id":"https://openalex.org/C2777983669","wikidata":"https://www.wikidata.org/wiki/Q223143","display_name":"Granulocyte","level":2,"score":0.5525962710380554},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5348609089851379},{"id":"https://openalex.org/C2779817106","wikidata":"https://www.wikidata.org/wiki/Q7834210","display_name":"Transfusion therapy","level":3,"score":0.48086029291152954},{"id":"https://openalex.org/C2777767877","wikidata":"https://www.wikidata.org/wiki/Q419327","display_name":"Granulocyte colony-stimulating factor","level":3,"score":0.45812663435935974},{"id":"https://openalex.org/C198677920","wikidata":"https://www.wikidata.org/wiki/Q3299937","display_name":"Neutrophile","level":3,"score":0.44425466656684875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36726564168930054},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.3325542211532593},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.2812509834766388},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.1567370891571045},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.07669761776924133},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C10205521","wikidata":"https://www.wikidata.org/wiki/Q4035578","display_name":"CD34","level":3,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":true},{"descriptor_ui":"D014019","descriptor_name":"Tissue Donors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014021","descriptor_name":"Tissue Preservation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016179","descriptor_name":"Granulocyte Colony-Stimulating Factor","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:10855364","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10855364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales de medecine interne","raw_type":"Journal Article"},{"id":"mag:2409655596","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10855364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2088989497","https://openalex.org/W2106803404","https://openalex.org/W2015816925","https://openalex.org/W2078288268","https://openalex.org/W1983037083","https://openalex.org/W1593763878","https://openalex.org/W2093230583","https://openalex.org/W1978324603","https://openalex.org/W2001385260","https://openalex.org/W1603430948"],"abstract_inverted_index":{"The":[0],"efficacy":[1,120],"of":[2,9,19,23,41,47,74,106,111,118,125],"neutrophil":[3,24,61],"transfusion":[4,80],"therapy":[5,102],"in":[6,55,58,83],"the":[7,17,39,59,104,116,123],"treatment":[8],"neutropenia-associated":[10],"infection":[11],"is":[12],"most":[13],"likely":[14],"dependent":[15],"on":[16,103],"dose":[18],"neutrophils":[20,42],"provided.":[21],"Stimulation":[22],"donors":[25],"with":[26,28],"G-CSF,":[27],"or":[29],"without":[30],"corticosteroids,":[31],"causes":[32],"marked":[33,84],"donor":[34],"neutrophilia":[35],"and":[36,94],"greatly":[37],"increases":[38,57],"number":[40],"collected":[43],"by":[44],"leukapheresis.":[45],"Transfusion":[46],"these":[48,112],"cells":[49,71,91],"into":[50],"severely":[51],"neutropenic":[52],"patients":[53],"results":[54,81,124],"substantial":[56],"patient's":[60],"count,":[62],"levels":[63],"which":[64],"are":[65,72,82,92],"sustained":[66],"for":[67,100],"24":[68],"hours.":[69],"These":[70,79],"capable":[73],"migrating":[75],"to":[76,86,97],"extravascular":[77],"sites.":[78],"contrast":[85],"those":[87],"observed":[88],"when":[89],"fewer":[90],"administered":[93],"have":[95],"led":[96],"great":[98],"enthusiasm":[99],"this":[101],"part":[105],"many":[107],"investigators.":[108],"In":[109],"spite":[110],"preliminary":[113],"encouraging":[114],"results,":[115],"determination":[117],"clinical":[119,127],"must":[121],"await":[122],"large":[126],"trials.":[128]},"counts_by_year":[{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}