{"id":"https://openalex.org/W2409360738","doi":null,"title":"Review Article Emerging Trends in Novel Drug Delivery System: Intra Nasal Drug Delivery","display_name":"Review Article Emerging Trends in Novel Drug Delivery System: Intra Nasal Drug Delivery","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2409360738","mag":"2409360738"},"language":"en","primary_location":{"id":"mag:2409360738","doi":null,"is_oa":false,"landing_page_url":"http://www.ijpcsonline.com/files/08-02-16/12-1052.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023690616","display_name":"G. Buvaneswari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"G. Buvaneswari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5023690616"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10984","display_name":"Sinusitis and nasal conditions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intranasal-drug-delivery","display_name":"intranasal drug delivery","score":0.9890000224113464},{"id":"https://openalex.org/keywords/nasal-mucosa","display_name":"nasal mucosa","score":0.8970000147819519},{"id":"https://openalex.org/keywords/nasal-absorption","display_name":"nasal absorption","score":0.9549999833106995},{"id":"https://openalex.org/keywords/first-pass-metabolism-avoidance","display_name":"first-pass metabolism avoidance","score":0.7070000171661377},{"id":"https://openalex.org/keywords/systemic-drug-delivery","display_name":"systemic drug delivery","score":0.7039999961853027},{"id":"https://openalex.org/keywords/drug-delivery-to-the-brain","display_name":"brain drug delivery","score":0.7570000290870667},{"id":"https://openalex.org/keywords/nasal-vaccine","display_name":"nasal vaccine","score":0.3610000014305115},{"id":"https://openalex.org/keywords/ayurveda","display_name":"Ayurveda","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C85663871","wikidata":"https://www.wikidata.org/wiki/Q6966562","display_name":"Nasal administration","level":2,"score":0.8586234450340271},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.7545642256736755},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7297829389572144},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.6687302589416504},{"id":"https://openalex.org/C2778801703","wikidata":"https://www.wikidata.org/wiki/Q156104","display_name":"Nasal cavity","level":2,"score":0.5891520977020264},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.5877025723457336},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5813418626785278},{"id":"https://openalex.org/C59377437","wikidata":"https://www.wikidata.org/wiki/Q515471","display_name":"Mucous membrane of nose","level":2,"score":0.4854479432106018},{"id":"https://openalex.org/C201253974","wikidata":"https://www.wikidata.org/wiki/Q1330121","display_name":"First pass effect","level":3,"score":0.43798312544822693},{"id":"https://openalex.org/C2776093070","wikidata":"https://www.wikidata.org/wiki/Q621636","display_name":"Route of administration","level":2,"score":0.43603426218032837},{"id":"https://openalex.org/C77281830","wikidata":"https://www.wikidata.org/wiki/Q718608","display_name":"Dosage form","level":2,"score":0.4177163243293762},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.15438884496688843},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.1402735412120819},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13529810309410095},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2409360738","doi":null,"is_oa":false,"landing_page_url":"http://www.ijpcsonline.com/files/08-02-16/12-1052.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":163,"referenced_works":["https://openalex.org/W113982171","https://openalex.org/W154395965","https://openalex.org/W184901588","https://openalex.org/W279227806","https://openalex.org/W657174950","https://openalex.org/W980027166","https://openalex.org/W1486133996","https://openalex.org/W1498528676","https://openalex.org/W1498725963","https://openalex.org/W1500605233","https://openalex.org/W1507292278","https://openalex.org/W1574797192","https://openalex.org/W1587951740","https://openalex.org/W1593106624","https://openalex.org/W1604852196","https://openalex.org/W1606400306","https://openalex.org/W1785448569","https://openalex.org/W1839771938","https://openalex.org/W1964882037","https://openalex.org/W1965721813","https://openalex.org/W1965944527","https://openalex.org/W1966433192","https://openalex.org/W1967239261","https://openalex.org/W1967503504","https://openalex.org/W1968220379","https://openalex.org/W1968632820","https://openalex.org/W1970149768","https://openalex.org/W1970421104","https://openalex.org/W1971449863","https://openalex.org/W1972788278","https://openalex.org/W1972979256","https://openalex.org/W1973551521","https://openalex.org/W1973587361","https://openalex.org/W1977311048","https://openalex.org/W1978985018","https://openalex.org/W1979276920","https://openalex.org/W1980380624","https://openalex.org/W1981095257","https://openalex.org/W1983445934","https://openalex.org/W1983634850","https://openalex.org/W1984335257","https://openalex.org/W1985346406","https://openalex.org/W1986144905","https://openalex.org/W1989268341","https://openalex.org/W1991260622","https://openalex.org/W1993552592","https://openalex.org/W1997090996","https://openalex.org/W1997209318","https://openalex.org/W1999617488","https://openalex.org/W2000640173","https://openalex.org/W2002613974","https://openalex.org/W2002877587","https://openalex.org/W2005417070","https://openalex.org/W2009808875","https://openalex.org/W2010929111","https://openalex.org/W2015263964","https://openalex.org/W2015782388","https://openalex.org/W2018340655","https://openalex.org/W2018963982","https://openalex.org/W2019267098","https://openalex.org/W2020965737","https://openalex.org/W2022369464","https://openalex.org/W2023353270","https://openalex.org/W2025100772","https://openalex.org/W2029093615","https://openalex.org/W2032569772","https://openalex.org/W2033348952","https://openalex.org/W2033404670","https://openalex.org/W2035224718","https://openalex.org/W2035704069","https://openalex.org/W2035802031","https://openalex.org/W2035961485","https://openalex.org/W2036607456","https://openalex.org/W2036794860","https://openalex.org/W2037002669","https://openalex.org/W2038622171","https://openalex.org/W2042336186","https://openalex.org/W2042896447","https://openalex.org/W2045670750","https://openalex.org/W2046906032","https://openalex.org/W2047603891","https://openalex.org/W2048939836","https://openalex.org/W2049458824","https://openalex.org/W2050946834","https://openalex.org/W2052363584","https://openalex.org/W2052526822","https://openalex.org/W2053511302","https://openalex.org/W2053944183","https://openalex.org/W2054753313","https://openalex.org/W2056589068","https://openalex.org/W2058322471","https://openalex.org/W2058457951","https://openalex.org/W2059582382","https://openalex.org/W2062825755","https://openalex.org/W2066311937","https://openalex.org/W2066703723","https://openalex.org/W2067309612","https://openalex.org/W2073700585","https://openalex.org/W2073771274","https://openalex.org/W2074568185","https://openalex.org/W2074971761","https://openalex.org/W2076052500","https://openalex.org/W2077969287","https://openalex.org/W2078218165","https://openalex.org/W2078930672","https://openalex.org/W2079946510","https://openalex.org/W2080195723","https://openalex.org/W2081695520","https://openalex.org/W2082641947","https://openalex.org/W2083120125","https://openalex.org/W2084310200","https://openalex.org/W2085264307","https://openalex.org/W2086776758","https://openalex.org/W2087247100","https://openalex.org/W2088730974","https://openalex.org/W2089895093","https://openalex.org/W2089978730","https://openalex.org/W2090063729","https://openalex.org/W2093239104","https://openalex.org/W2094687363","https://openalex.org/W2099366654","https://openalex.org/W2100217583","https://openalex.org/W2100300954","https://openalex.org/W2100333303","https://openalex.org/W2100837325","https://openalex.org/W2101445492","https://openalex.org/W2116835281","https://openalex.org/W2123415498","https://openalex.org/W2126446846","https://openalex.org/W2130300976","https://openalex.org/W2135309893","https://openalex.org/W2163287967","https://openalex.org/W2163771644","https://openalex.org/W2169845201","https://openalex.org/W2181877845","https://openalex.org/W2184547078","https://openalex.org/W2185391380","https://openalex.org/W2186474562","https://openalex.org/W2186848877","https://openalex.org/W2186921694","https://openalex.org/W2187548393","https://openalex.org/W2187694640","https://openalex.org/W2188365720","https://openalex.org/W2189452761","https://openalex.org/W2189499781","https://openalex.org/W2261218573","https://openalex.org/W2279251696","https://openalex.org/W2313247510","https://openalex.org/W2318656528","https://openalex.org/W2319365542","https://openalex.org/W2333598317","https://openalex.org/W2395378785","https://openalex.org/W2396531593","https://openalex.org/W2402639495","https://openalex.org/W2404501552","https://openalex.org/W2412185540","https://openalex.org/W2419283568","https://openalex.org/W2478522723","https://openalex.org/W2493441696","https://openalex.org/W2493472155","https://openalex.org/W2560500588","https://openalex.org/W2603919945","https://openalex.org/W4243476978"],"related_works":["https://openalex.org/W2185391380","https://openalex.org/W2898510755","https://openalex.org/W4390516205","https://openalex.org/W7099302092","https://openalex.org/W6968304680","https://openalex.org/W2259756160","https://openalex.org/W7098787888","https://openalex.org/W2318656528","https://openalex.org/W2955832244","https://openalex.org/W754894681"],"abstract_inverted_index":{"Delivery":[0],"of":[1,16,36,42,48,58,66,73,76,89,94,105,123,158,166,184],"drugs":[2,139],"through":[3],"nasal":[4,90,111,143,159,167,173,180,185],"route":[5,13],"has":[6,32],"been":[7,33],"potentially":[8],"explored":[9],"as":[10,22,147],"an":[11],"alternative":[12],"for":[14,102,116,130],"administration":[15,60],"vaccines,":[17],"hormones":[18],"and":[19,25,55,61,92,133,163,182],"biomolecules":[20],"such":[21,146],"proteins,":[23],"peptides":[24],"non":[26],"-":[27],"peptide":[28],"drugs.":[29,78],"Intranasal":[30],"therapy":[31],"accepted":[34],"form":[35],"treatment":[37],"in":[38,64,191],"the":[39,45,71,81],"ayurvedic":[40],"system":[41,136,188],"medicines.":[43],"Considering":[44],"large":[46],"number":[47],"problems":[49],"associated":[50],"with":[51],"oral,":[52],"parenteral,":[53],"rectal":[54],"other":[56],"routes":[57],"drug":[59,106,118,168,186],"gradual":[62],"increase":[63],"interest":[65],"pharmaceutical":[67],"scientists":[68],"towards":[69],"exploring":[70],"possibilities":[72],"intranasal":[74],"delivery":[75,104,144,169,187],"various":[77],"Due":[79],"to":[80,178],"high":[82,84],"permeability,":[83],"vasculature,":[85],"low":[86],"enzymatic":[87],"environment":[88],"cavity":[91],"avoidance":[93],"hepatic":[95],"first":[96],"pass":[97],"metabolism":[98],"are":[99,140,189],"well":[100],"suitable":[101],"systemic":[103,132],"molecule":[107],"via":[108],"nose.":[109],"Since":[110],"mucosa":[112],"offer":[113],"several":[114],"benefits":[115],"target":[117],"delivery,":[119],"a":[120],"wide":[121],"variety":[122],"therapeutic":[124],"compounds":[125],"may":[126],"be":[127],"administered":[128,141],"intranasally":[129],"topical,":[131],"central":[134],"nervous":[135],"action.":[137],"The":[138,155],"by":[142],"devices":[145,153],"powder":[148],"devices,":[149,151],"liquid":[150],"semisolid":[152],"etc.":[154],"different":[156],"aspects":[157],"anatomy,":[160],"advantages,":[161],"disadvantages":[162],"ideal":[164],"properties":[165],"system,":[170],"factors":[171],"affecting":[172],"absorption,":[174],"bioavailability":[175],"barriers,":[176],"strategies":[177],"improve":[179],"absorption":[181],"applications":[183],"discussed":[190],"this":[192],"article.":[193]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}